Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

tpf1 (P16665) - Overview - Molecular Target Synopsis

Protein


tpf1, Antigen TpF1
UniProt P16665

Also Known as TPF1_TREPA, tpf1

May play an important structural role in the outer membrane. Homodecamer; either linked or stabilized by disulfide bonds.

2FJC
CRYSTAL STRUCTURE OF ANTIGEN TPF1 FROM TREPONEMA PALLIDUM
RCSB/PDB
Inspect Structure
See all 3D Structures for tpf1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
177P16665-1

Sub-cellular localization


GO terms: tpf1 is active in the following subcellular-locations: cell.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project tpf1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For tpf1 there are:
1 structures (16 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis