NMT1, Glycylpeptide N-tetradecanoyltransferase
Enzyme Classification 188.8.131.52
Also Known as
NMT_YEAST, NMT1, CDC72
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Substrate specificity requires an N-terminal glycine in the nascent polypeptide substrates. Uncharged amino acids are preferred at position 2 while neutral residues are favored at positions 3 and 4. Ser is present at position 5 in almost all known N-myristoyl proteins and Lys is commonly encountered at postion 6. Monomer.