Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ALB (P14639) - Overview - Molecular Target Synopsis

Protein


ALB, Serum albumin
UniProt P14639

Also Known as ALBU_SHEEP, ALB

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

5ORF
STRUCTURE OF OVINE SERUM ALBUMIN IN P1 SPACE GROUP
RCSB/PDB
Inspect Structure
See all 3D Structures for ALB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
607P14639-1

Sub-cellular localization


UniProt: ALB is active in the following subcellular-locations: secreted.
GO terms: ALB is active in the following subcellular-locations: extracellular space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ALB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For ALB there are:
3 structures (6 chains) solved
3 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


ALB has been screened with compounds ( bioactivities). (see details)