Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

ACYP2 (P14621) - Overview - Molecular Target Synopsis


ACYP2, Acylphosphatase-2
Enzyme Classification
UniProt P14621

Also Known as ACYP2_HUMAN, ACYP2, ACYP

Its physiological role is not yet clear.

Isoforms / Transcripts (Protein Coding)

Gene Copy Number Variation

In COSMIC - Cell Lines Project ACYP2 has gain in 1 cell-lines, loss in 0 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: SN12C, SR, SNB_19

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC2688, SU-DHL-4, DV-90

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, A549

(see details)

3D Structures

At greater than 90% identity similarity to ACYP2 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand

(see details)
Molecular Target 3D Synopsis