Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpl19e (P14119) - Overview - Molecular Target Synopsis

Protein


rpl19e, 50S ribosomal protein L19e
UniProt P14119

Also Known as RL19E_HALMA, rpl19e

Binds to the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit. Part of the 50S ribosomal subunit.

3OW2
CRYSTAL STRUCTURE OF ENHANCED MACROLIDE BOUND TO 50S RIBOSOMAL SUBUNIT
RCSB/PDB
Inspect Structure
See all 3D Structures for rpl19e

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
149P14119-1

Sub-cellular localization


GO terms: rpl19e is active in the following subcellular-locations: cytosolic large ribosomal subunit.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpl19e has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpl19e there are:
67 structures (67 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


rpl19e has been screened with compounds ( bioactivities). (see details)