Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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Germline Genetics

petC (P13627) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 07/05/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 07/05/2019)


Chains assessed2
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria2


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
2YIU_E Cytochrome c1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 61.6 36.9 Yes No
2 empty 1.8 65.4 14 No No
3 empty 2.21 56.1 13.7 No No
4 empty 2.62 65.9 17.2 No No
5 empty 2.16 61.4 14.3 No No
6 empty 1.07 61.5 15.1 No No
7 empty 2.59 62.2 14.9 No No
8 empty 2.03 66.9 11.5 No No
9 empty 1.91 82.3 7.8 No No
10 empty 2.27 64.4 11.2 No No
2YIU_B Cytochrome c1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 62.4 36 Yes No
2 empty 2.06 67.5 17.3 No No
3 empty 2.68 66.2 19.5 No No
4 empty 2.25 56.6 13.2 No No
5 empty 2.23 64.5 15.1 No No
6 empty 1.06 61.5 16.2 No No
7 empty 1.98 68.8 11.1 No No
8 empty 1.91 79.2 9.6 No No
9 empty 2.45 52.2 11.7 No No
10 empty 1.59 58.3 9.6 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed2
Domains assessed as druggable using the strict criteria0
Domains assessed as druggable using the relaxed criteria2

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
2YIU_B (4203142) Cytochrome c1 Cytochrome c, Cytochrome c, Cytochrome bc1 domain 2.7Å Yes No
2YIU_E (4203141) Cytochrome c1 Cytochrome c, Cytochrome c, Cytochrome bc1 domain 2.7Å Yes No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score