Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pgiB (P13376) - Overview - Molecular Target Synopsis

Protein


pgiB, Glucose-6-phosphate isomerase B
Enzyme Classification 5.3.1.9
UniProt P13376

Also Known as G6PIB_GEOSE, pgiB

Homodimer.

1C7Q
THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE/AUTOCRINE MOTILITY FACTOR/NEUROLEUKIN COMPLEXED WITH ITS CARBOHYDRATE PHOSPHATE INHIBITORS AND ITS SUBSTRATE RECOGNITION MECHANISM
RCSB/PDB
Inspect Structure
See all 3D Structures for pgiB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
445P13376-1

Sub-cellular localization


UniProt: pgiB is active in the following subcellular-locations: cytoplasm.
GO terms: pgiB is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project pgiB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pgiB there are:
4 structures (4 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis