Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpl21e (P12734) - Overview - Molecular Target Synopsis

Protein


rpl21e, 50S ribosomal protein L21e
UniProt P12734

Also Known as RL21_HALMA, rpl21e

This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Part of the 50S ribosomal subunit. Interacts with protein L18 and binds the 5S rRNA. Has been cross-linked to L18.

3OW2
CRYSTAL STRUCTURE OF ENHANCED MACROLIDE BOUND TO 50S RIBOSOMAL SUBUNIT
RCSB/PDB
Inspect Structure
See all 3D Structures for rpl21e

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
96P12734-1

Sub-cellular localization


GO terms: rpl21e is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpl21e has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpl21e there are:
67 structures (67 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis