Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpl18e (P12733) - Overview - Molecular Target Synopsis

Protein


rpl18e, 50S ribosomal protein L18e
UniProt P12733

Also Known as RL18E_HALMA, rpl18e

Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain II) to which it binds. Part of the 50S ribosomal subunit. Interacts weakly with proteins L4 and L15. Has been cross-linked to L4.

3OW2
CRYSTAL STRUCTURE OF ENHANCED MACROLIDE BOUND TO 50S RIBOSOMAL SUBUNIT
RCSB/PDB
Inspect Structure
See all 3D Structures for rpl18e

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
116P12733-1

Sub-cellular localization


GO terms: rpl18e is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpl18e has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpl18e there are:
67 structures (67 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis