Molecular Target Synopsis
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pdhC (P11961) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 10/09/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 10/09/2019)


Chains assessed24
Chains with at least one site assessed as druggable using the strict criteria6
Chains with at least one site assessed as druggable using the relaxed criteria10


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
1W85_I Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 59.5 13.2 No No
2 empty 2.35 63.3 8.9 No No
3 empty 1.98 66.7 8.7 No No
4 empty 3.39 68.9 5.8 No No
5 empty 1.95 63.2 6.5 No No
3DVA_I Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.61 57.1 15.9 No No
2 empty 2.51 61.3 13.9 No No
3 empty 1.75 62.3 9.7 No No
4 empty 2.12 67.3 7 No No
5 empty 2.59 57.1 7.5 No No
6 empty 3.55 59.1 5.6 No No
7 empty 1.68 59.7 5.7 No No
3DUF_J Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.5 77.4 12.1 Yes No
2 empty 2.49 64.3 11.6 No No
3 empty 2.72 52.4 13 No No
4 empty 2.52 63.5 9.1 No No
5 empty 1.81 55.1 7.4 No No
6 empty 2.66 57 6.6 No No
7 empty 3.33 57.8 6.7 No No
8 empty 2.84 71.8 5 No No
1LAC_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.51 72.7 16.7 Yes No
2 empty 1.89 57.4 14.8 No No
3 empty 1.93 73.7 7.7 No No
4 empty 2.21 59.5 13.3 No No
5 empty 2.15 71.3 8.1 No No
6 empty 2.6 68.4 8.6 No No
7 empty 1.85 57.8 7.4 No No
8 empty 2.53 72.9 6.3 No No
9 empty 2.38 50 5.9 No No
10 empty 2.28 61.9 8.9 No No
1B5S_B Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .9 75.4 47.9 Yes Yes
2 empty 1.61 34.5 16.9 No No
3 empty 1.4 56.2 15.3 No No
4 empty 1.84 71.4 10.3 No No
5 empty 1.88 73.7 7.7 No No
6 empty 2.02 79.9 11.6 No No
7 empty 1.5 59.9 15.2 No No
8 empty 2.12 45.4 9.6 No No
9 empty 1.86 50 7.8 No No
10 empty 1.71 65.6 8.7 No No
1W88_J Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.52 68 9.3 No No
2 empty 2.45 56.5 14.5 No No
3 empty 2.15 59.5 11.4 No No
4 empty 2.74 65.8 0 No No
5 empty 1.54 74.2 0 No No
3DUF_I Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.46 62.1 22 No No
2 empty 2.43 61.2 9.2 No No
3 empty 2.38 61.7 12 No No
4 empty 1.97 57.6 7.9 No No
5 empty 1.81 71.4 0 No No
6 empty 2.15 45.5 6.8 No No
7 empty 1.91 67.5 5.6 No No
8 empty 1.42 96.1 0 Yes No
9 empty 2.87 75.9 5.6 No No
10 empty 3.14 74.2 0 No No
1W3D_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.7 63.2 21.2 No No
2 empty 2.62 65.7 14.1 No No
3 empty 2.72 68.1 8.6 No No
4 empty 2.14 62.9 6.7 No No
5 empty 2.73 45.6 6.8 No No
6 empty 3.24 62.2 8.3 No No
7 empty 1.74 55.2 5.6 No No
8 empty 2.73 69.8 5.6 No No
9 empty 2.93 54.1 4.9 No No
10 empty 2.54 44.4 5.1 No No
3DVA_J Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.69 68.9 15.7 No No
2 empty 2.44 69.6 10.3 No No
3 empty 2.5 69.3 11.8 No No
4 empty 2.4 69 7.3 No No
5 empty 3.08 54.5 6.3 No No
6 empty 1.98 60.9 6.8 No No
7 empty 2.11 64.4 5.3 No No
1W85_J Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 67.1 16.1 No No
2 empty 2.45 79.1 10.3 Yes Yes
3 empty 2.55 62.1 17.7 No No
4 empty 3.38 72 0 No No
5 empty 2.43 68.4 5.7 No No
1LAB_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.25 72.1 27 Yes No
2 empty 2.29 74.4 10 No No
3 empty 2.24 65.8 10.2 No No
4 empty 2 68 11 No No
5 empty 1.81 54.8 12.4 No No
6 empty 2.44 63.3 11 No No
7 empty 2.32 73.4 6.9 No No
8 empty 1.96 47 7.8 No No
9 empty 2.93 61.7 7 No No
10 empty 2.69 70.9 4.5 No No
2PDD_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.47 63.7 19.4 No No
2 empty 2.13 63.2 20.1 No No
3 empty 2.21 55.7 8.4 No No
4 empty 1.44 49.1 9.7 No No
5 empty 2.08 71.9 6.1 No No
6 empty 3 55.8 7.2 No No
7 empty 2.97 53.7 6.6 No No
8 empty 3.26 70.4 5.3 No No
1B5S_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .88 78.2 37.3 Yes Yes
2 empty 1.68 70.8 40.3 No No
3 empty 1.77 62.4 23.9 No No
4 empty 1.63 35 17 No No
5 empty 1.75 73.5 10 No No
6 empty 1.66 77.2 7.5 No No
7 empty 1.7 51.7 8.5 No No
8 empty 1.63 57.9 8 No No
9 empty 1.89 41.4 8.3 No No
10 empty 1.99 99.3 0 Yes No
1EBD_C Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.56 64.3 18.1 No No
2 empty 2.37 61.8 11.5 No No
3 empty 1.79 68.8 8.7 No No
4 empty 2.92 65.9 6.1 No No
5 empty 3.27 68.4 5.9 No No
1B5S_E Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .9 75.3 47 Yes Yes
2 empty 1.62 35.7 16.5 No No
3 empty 1.47 56 18.6 No No
4 empty 1.68 68.7 12.4 No No
5 empty 1.73 78.5 8.5 No No
6 empty 1.92 44.8 9.6 No No
7 empty 1.61 55.9 9.2 No No
8 empty 1.91 99.3 0 Yes No
9 empty 1.88 50.9 8.2 No No
10 empty 2.27 62.7 7.7 No No
1W4E_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.88 62.7 22.3 No No
2 empty 2.22 51.8 14.4 No No
3 empty 2.82 67.4 10.7 No No
4 empty 2.8 51.7 9.4 No No
5 empty 3.05 64.9 7.4 No No
6 empty 2.32 63.7 6.6 No No
7 empty 2.1 50.6 9.1 No No
8 empty 2.52 71 5.9 No No
1B5S_D Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .89 74.9 47.6 Yes Yes
2 empty 1.84 62.3 23.8 No No
3 empty 1.68 35 16.7 No No
4 empty 1.9 79.2 12.2 No No
5 empty 2.05 78.9 9 No No
6 empty 1.95 44.3 8.6 No No
7 empty 1.65 53.3 9.1 No No
8 empty 1.88 46.6 9.1 No No
9 empty 1.75 64.1 8.2 No No
10 empty 1.29 53.2 7.9 No No
2PDE_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.58 61 22 No No
2 empty 1.69 62.1 10.7 No No
3 empty 2.7 66 6.3 No No
4 empty 2.55 66.7 5.6 No No
5 empty 1.07 58 8.2 No No
1B5S_C Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .88 75.3 47.9 Yes Yes
2 empty 1.79 60.5 22.9 No No
3 empty 1.62 34.9 16.5 No No
4 empty 1.61 71 10.1 No No
5 empty 1.73 72.1 11.3 No No
6 empty 1.89 77.4 10.9 No No
7 empty 1.8 77.5 6.6 No No
8 empty 1.93 45.6 8.8 No No
9 empty 1.62 55.1 9.8 No No
10 empty 1.83 48.1 8.7 No No
3DV0_J Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.69 70.2 16.8 No No
2 empty 2.17 65.6 7 No No
3 empty 2.14 69.4 9.1 No No
1W4G_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.66 64.2 16.7 No No
2 empty 2.14 56.7 13.9 No No
3 empty 2.44 63.4 10.8 No No
4 empty 2.57 56.5 11.1 No No
5 empty 3.42 62.4 8.7 No No
6 empty 2.41 64.4 6.4 No No
7 empty 2.26 69.5 6.1 No No
8 empty 1.89 66.7 5 No No
9 empty 2.63 47.4 5.7 No No
10 empty 2.7 67.1 6.4 No No
1W88_I Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.43 57.3 19.3 No No
2 empty 2.33 64.5 11.4 No No
3 empty 2.53 74.4 0 No No
4 empty 2.39 68.8 5.9 No No
3DV0_I Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.41 63.6 10.3 No No
2 empty 2.19 64.6 9.8 No No
3 empty 2.41 64.4 7.1 No No
4 empty 1.81 58.7 8.8 No No
1W4F_A Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.53 61.2 16.6 No No
2 empty 2.87 69.5 12.3 No No
3 empty 2.49 59.5 10.5 No No
4 empty 2.4 63 10.1 No No
5 empty 2.73 59.7 5.8 No No
6 empty 2.32 61.3 9.3 No No
7 empty 2.35 64 5.1 No No
8 empty 3.95 52.1 6.5 No No
9 empty 3.69 48.7 5.1 No No
10 empty 2.85 59.6 5 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed33
Domains assessed as druggable using the strict criteria6
Domains assessed as druggable using the relaxed criteria7

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1B5S_C (32628) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 4.4Å Yes Yes
1B5S_E (32630) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 4.4Å Yes Yes
1B5S_B (32627) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 4.4Å Yes Yes
1B5S_A (32626) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 4.4Å Yes Yes
1B5S_D (32629) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 4.4Å Yes Yes
1EBD_C (16355) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.6Å No No
1LAB_A (28226) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Barrel-sandwich hybrid, Single hybrid motif, Biotinyl/lipoyl-carrier proteins and domains Yes No
1LAC_A (28225) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Barrel-sandwich hybrid, Single hybrid motif, Biotinyl/lipoyl-carrier proteins and domains Yes No
1W3D_A (109151) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex No No
1W4E_A (3010921) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, UNMATCHED No No
1W4F_A (3010922) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, UNMATCHED No No
1W4G_A (3010923) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, UNMATCHED No No
1W85_I (114347) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2Å No No
1W85_J (114348) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2Å No Yes
1W88_I (114361) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.1Å No No
1W88_J (114362) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.1Å No No
2PDD_A (16358) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex No No
2PDE_A (16359) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex No No
3DUF_I (3370158) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Barrel-sandwich hybrid, Single hybrid motif, UNMATCHED 2.5Å No No
3DUF_I (3370160) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, UNMATCHED 2.5Å No No
3DUF_I (3370161) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.5Å No No
3DUF_I (3370159) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.5Å No No
3DUF_I (3370162) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 2.5Å No No
3DV0_I (3370193) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Barrel-sandwich hybrid, Single hybrid motif, UNMATCHED 2.5Å No No
3DV0_I (3370194) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.5Å No No
3DV0_I (3370195) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, UNMATCHED 2.5Å No No
3DV0_I (3370196) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.5Å No No
3DV0_I (3370197) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 2.5Å No No
3DVA_I (3370217) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.35Å No No
3DVA_I (3370216) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, UNMATCHED 2.35Å No No
3DVA_I (3370215) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex, Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 2.35Å No No
3DVA_I (3370214) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Barrel-sandwich hybrid, Single hybrid motif, UNMATCHED 2.35Å No No
3DVA_I (3370218) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex CoA-dependent acyltransferases, CoA-dependent acyltransferases, CAT-like 2.35Å No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score