Molecular Target Synopsis
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PIM1 (P11309) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 03/09/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 03/09/2019)


Chains assessed162
Chains with at least one site assessed as druggable using the strict criteria145
Chains with at least one site assessed as druggable using the relaxed criteria161


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
5V82_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 74.6 40.2 Yes Yes
2 empty 2.49 69.7 32.9 No No
3 empty 2.4 64.8 27.9 No No
4 empty 2.24 62.2 16.1 No No
5 empty 2.32 57.8 15.9 No No
6 empty 1.62 68.9 10.9 No No
7 empty 2.41 62.9 12.5 No No
8 empty 2.71 62.3 13.7 No No
9 empty 2.15 70.6 9.3 No No
10 empty 1.84 57.5 18.3 No No
4N70_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 76.6 38.7 Yes Yes
2 empty 2.53 65.7 37.7 No No
3 empty 2.13 62.9 15 No No
4 empty 1.98 73.8 16.1 No No
5 empty 1.66 69.9 12.4 No No
6 empty 2.36 61.9 10.7 No No
7 empty 2.2 60.1 11.8 No No
8 empty 2.57 65.2 15.1 No No
9 empty 1.88 59.2 16.9 No No
10 empty 1.95 69.7 7.5 No No
5N4Z_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 71.9 40.1 Yes Yes
2 empty 2.18 66.7 28.6 No No
3 empty 2.51 66.3 33.2 No No
4 empty 1.94 61.3 17.5 No No
5 empty 1.93 69.8 14.3 No No
6 empty 2.53 59.4 15.6 No No
7 empty 2.28 69.7 13.9 No No
8 empty 2.18 82.8 9.4 No No
9 empty 2.33 60.7 11.4 No No
10 empty 2.23 58.5 11.1 No No
3R00_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.29 72.9 38.8 Yes Yes
2 empty 2.42 64.4 33.1 No No
3 empty 2.35 65.3 15.5 No No
4 empty 2.06 55.4 20.6 No No
5 empty 2.54 63 19.5 No No
6 bound 1.94 68.8 16.6 No No
7 empty 1.62 72.9 11.7 No No
8 empty 2.56 64.4 17.1 No No
9 empty 2.53 60.4 14 No No
10 empty 2.01 57.9 16.7 No No
2BZJ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 75.1 38.4 Yes Yes
2 empty 2.17 65.7 36.8 No No
3 empty 2.46 66.7 32.3 No No
4 empty 2.32 64.6 19 No No
5 empty 2.43 61.7 11.4 No No
6 empty 2.1 69 13.4 No No
7 empty 2.67 66.2 12.9 No No
8 empty 1.86 65.3 11.7 No No
9 empty 2.35 63.1 11.1 No No
10 empty 2.22 67.7 8.8 No No
1XR1_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 71 41.9 Yes Yes
2 empty 2.47 67.8 33.5 No No
3 empty 2.25 65.6 25.2 No No
4 empty 2.3 63.7 19.9 No No
5 empty 2.31 64.5 19.3 No No
6 empty 2.17 57.1 16 No No
7 empty 1.73 70.2 12 No No
8 empty 2.35 62.6 12.7 No No
9 empty 1.88 64.8 10.2 No No
10 empty 2.79 64.1 12.1 No No
3JXW_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 74.1 38.9 Yes Yes
2 empty 2.26 65.1 39.4 No No
3 empty 2.29 66 16.5 No No
4 empty 2.3 64.8 20.7 No No
5 empty 1.78 57.9 16.8 No No
6 empty 2.16 63.5 13.8 No No
7 empty 1.51 69.2 10.3 No No
8 empty 2.61 63.8 13.8 No No
9 empty 2.57 61.5 10.7 No No
10 empty 1.9 67.4 11.7 No No
5O12_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 67.5 30.2 Yes Yes
2 empty 2.2 61.3 18.4 No No
3 empty 2.41 62.5 19.9 No No
4 empty 1.5 67.4 13.4 No No
5 empty 2.26 61.3 11.5 No No
6 empty 2.01 59.2 14.2 No No
7 empty 2.15 57.1 12 No No
8 empty 1.76 74.6 11.7 No No
9 empty 1.96 68.1 11.1 No No
10 empty 1.99 54 11.2 No No
5EOL_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 75.9 38 Yes Yes
2 empty 2.51 64.1 32.8 No No
3 bound 2.37 63.1 18 No No
4 empty 2.22 65.4 19.8 No No
5 empty 1.67 72.8 11.4 No No
6 empty 2.5 65.2 18.1 No No
7 empty 2.51 59.6 13.2 No No
8 empty 2.19 67.7 11.3 No No
9 empty 2.61 65.8 13.4 No No
10 empty 1.83 59.4 15.9 No No
4DTK_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 75.6 39.4 Yes Yes
2 bound 2.37 65.8 34.2 No No
3 bound 2.26 64.7 16.8 No No
4 bound 2.21 65.9 23.3 No No
5 bound 2.51 63.3 21 No No
6 empty 1.54 72 12.4 No No
7 bound 2.6 60.9 10.6 No No
8 empty 2.6 64.2 13.4 No No
9 empty 1.86 59.2 16.9 No No
10 empty 1.79 67.1 11.6 No No
1YXX_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 76.5 37.9 Yes Yes
2 empty 2.4 65.9 34.6 No No
3 empty 2.41 63.9 17 No No
4 empty 1.9 66.6 21.4 No No
5 empty 2.56 68.5 15.2 No No
6 bound 2.18 67.1 15.5 No No
7 empty 1.54 72.8 12.1 No No
8 empty 2.46 59.8 13.1 No No
9 empty 2.45 62.1 13.8 No No
10 empty 2.52 65.7 15.3 No No
5KGK_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 76 38.9 Yes Yes
2 bound 2.45 65.1 34.8 No No
3 empty 2.42 65.1 20.9 No No
4 bound 2.26 64.9 26.1 No No
5 empty 1.54 72.5 11.9 No No
6 empty 2.47 62.2 13.4 No No
7 empty 2.41 66.2 10.8 No No
8 empty 2.16 62.8 14.8 No No
9 empty 1.89 70 10.2 No No
10 empty 1.67 60.4 10.5 No No
1YXU_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 69.8 43.4 Yes Yes
2 empty 2.61 64.4 39.9 No No
3 bound 2.19 68.5 18.2 No No
4 empty 2.41 70.7 17 No No
5 empty 1.62 70.8 14 No No
6 empty 2.55 56.5 14.9 No No
7 empty 2.51 67.9 17.9 No No
8 empty 2.05 60 18.6 No No
9 empty 1.93 59.5 11 No No
10 empty 2.34 61.6 12.8 No No
4XH6_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.27 72.9 40.6 Yes Yes
2 empty 2.36 68.1 27.7 No No
3 empty 2.46 65.1 34.1 No No
4 empty 2.33 63 24.9 No No
5 empty 2.18 68.6 17.1 No No
6 empty 2.66 67.3 12.7 No No
7 empty 2.48 62.8 10.5 No No
8 empty 2.17 55.1 14.9 No No
9 empty 2.35 64.6 9.9 No No
10 empty 2.02 73.9 11.4 No No
1XQZ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 76.1 38.4 Yes Yes
2 empty 2.55 70.8 31.8 No No
3 empty 2.2 65.3 25.6 No No
4 empty 2.3 63.2 20.5 No No
5 empty 2.16 60.1 18.6 No No
6 empty 2.2 55.7 16.5 No No
7 empty 1.5 75.8 11.1 No No
8 empty 2.48 60.2 13.7 No No
9 empty 2.07 68.4 8.7 No No
10 empty 2.27 59.4 12.8 No No
5NDT_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 74 40.7 Yes Yes
2 empty 2.14 67.2 23.9 No No
3 empty 2.4 67.5 34.1 No No
4 empty 2.64 59.2 22.8 No No
5 empty 1.5 59.9 14.6 No No
6 empty 1.97 73.2 16.5 No No
7 bound 1.94 66 10.3 No No
8 empty 2.06 65.9 9.8 No No
9 empty 1.88 78.3 10.5 No No
10 empty 2.3 61.2 11.8 No No
2XIX_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 74.2 33.1 Yes Yes
2 empty 2.53 67.3 34 No No
3 empty 2.25 65.3 17.1 No No
4 empty 2.21 66.5 20.1 No No
5 empty 2.28 62.4 13.7 No No
6 empty 1.66 70.4 10.6 No No
7 empty 2.37 62.3 12.5 No No
8 empty 2.52 66.8 11.6 No No
9 empty 1.88 63.1 12.2 No No
10 empty 1.95 59.2 11.9 No No
5IPJ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 75.1 39.8 Yes Yes
2 empty 2.55 66.6 35.4 No No
3 bound 2.31 65 19.1 No No
4 empty 1.94 66.7 21.8 No No
5 empty 2.47 65.1 13.8 No No
6 empty 1.7 70.8 11.2 No No
7 empty 2.5 60.8 12.4 No No
8 empty 2.65 66 12.9 No No
9 empty 1.99 59.4 15.4 No No
10 bound 2.37 61 19.5 No No
3QF9_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 74.1 31 Yes Yes
2 empty 2.44 67.8 35.5 No No
3 empty 2.33 68.4 27.4 No No
4 empty 2.53 62.6 10.1 No No
5 empty 2 57 15.6 No No
6 empty 2.39 69.8 13.5 No No
7 empty 2.44 63.9 15.7 No No
8 empty 1.46 61 14.9 No No
9 empty 2.01 69.4 9.3 No No
10 empty 1.93 65 11 No No
6PCW_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 73.3 31.1 Yes Yes
2 empty 2.15 67.1 25.1 No No
3 empty 2.49 67.7 33.6 No No
4 empty 2.09 64.5 24.1 No No
5 bound 2.05 55.6 17.8 No No
6 empty 1.93 68.6 14.6 No No
7 empty 1.8 65 9.6 No No
8 bound 2.39 64.1 10.6 No No
9 empty 1.97 66.2 9.5 No No
10 empty 2.45 66.2 11.1 No No
4MED_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.31 66.3 53.5 Yes Yes
2 bound 2.11 75.6 38.3 No No
3 empty 2.26 67.1 25 No No
4 empty 2.12 60.8 30.8 No No
5 empty 2.41 62.5 12.8 No No
6 empty 2.36 61 13 No No
7 empty 1.94 67.2 9.5 No No
8 empty 2.48 67.8 10.7 No No
9 empty 2.23 71.4 8.7 No No
10 empty .94 96.4 0 Yes No
5VUC_B Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.34 65.5 52.6 Yes No
2 bound 1.94 75.4 33.1 No No
3 bound 2.09 65.1 23.3 No No
4 empty 2.32 73 15.4 No No
5 empty 2.06 55.9 19.4 No No
6 empty 2.5 63.2 12.9 No No
7 empty 2.27 65.9 15 No No
8 empty 2.83 67.4 8.2 No No
9 empty 2.36 63.3 9.7 No No
10 empty 2.32 70.5 9 No No
6BSK_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 74 38.6 Yes Yes
2 bound 2.44 66.3 33.1 No No
3 empty 2.27 63.8 22.4 No No
4 empty 2.27 65.7 27.5 No No
5 bound 2.49 64.7 15 No No
6 empty 1.64 68.9 13.7 No No
7 empty 2.58 63.8 17.3 No No
8 empty 1.91 58.7 17.6 No No
9 empty 1.95 64.8 11.3 No No
10 empty 1.85 57.1 10.9 No No
5KGE_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 74.2 41.4 Yes Yes
2 bound 2.54 66.6 33.9 No No
3 empty 2.43 64.3 21.6 No No
4 bound 2.22 65.1 23.6 No No
5 empty 1.6 67.2 14.6 No No
6 empty 2.47 62.3 11.9 No No
7 empty 2.54 62.3 12.3 No No
8 empty 2.12 58.7 14.7 No No
9 bound 1.9 75.7 10 No No
10 empty 2.28 68.2 10 No No
1YXU_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 76.3 36.9 Yes Yes
2 empty 2.54 64.4 37.1 No No
3 empty 2.37 66 19.9 No No
4 bound 2.33 66.2 24.8 No No
5 empty 1.63 70.7 10.7 No No
6 empty 2.45 61.7 13.4 No No
7 empty 2 56.8 14.8 No No
8 empty 2.5 65.6 12.3 No No
9 empty 2.21 76.2 12 No No
10 empty 1.77 62 11.1 No No
2XIY_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.98 74.8 33.1 Yes Yes
2 empty 2.6 66.3 30.1 No No
3 empty 2.36 66.1 15.2 No No
4 bound 2 71.1 16.1 No No
5 empty 2.49 58.8 16 No No
6 empty 2.39 68.1 13.7 No No
7 empty 1.69 70 10 No No
8 empty 2.59 65.9 14 No No
9 empty 2.35 59.4 12.5 No No
10 empty 1.83 65.3 12.6 No No
4RC3_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 74.1 37.6 Yes Yes
2 empty 2.24 66.2 28.8 No No
3 empty 2.46 66.3 31.5 No No
4 empty 2.24 69 25.3 No No
5 empty 2.12 59.6 23.8 No No
6 empty 2.4 66.4 12.4 No No
7 empty 2.46 59 11.7 No No
8 empty 2.34 72.9 10.7 No No
9 empty 1.86 62.5 9.7 No No
10 empty 2.05 58.4 11.2 No No
3BWF_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 73.3 40.3 Yes Yes
2 empty 2.25 66.8 27.7 No No
3 bound 2.62 69 32.4 No No
4 empty 1.98 63.2 15.6 No No
5 empty 2.41 72.9 16.6 No No
6 empty 2.3 64.1 12.7 No No
7 empty 1.83 54.8 15.4 No No
8 empty 2.32 64.6 13.3 No No
9 empty 1.87 79.7 12.6 No No
10 empty 2.27 61.4 9.4 No No
4ALW_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 75.3 37.5 Yes Yes
2 bound 2.35 63.9 35.2 No No
3 empty 2.37 63.1 18.4 No No
4 bound 2.15 71.4 13.4 No No
5 empty 2.59 66.1 18.5 No No
6 empty 1.63 70.7 11.5 No No
7 empty 2.49 63.7 10.9 No No
8 empty 1.93 56.1 17.1 No No
9 empty 2.25 65.7 11.1 No No
10 empty 1.75 70.3 8.7 No No
4LMU_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.31 64.3 53.9 Yes No
2 bound 2.09 74 38.3 No No
3 bound 2.26 64.8 27.7 No No
4 empty 2.13 71.5 12.5 No No
5 empty 2.5 60.8 13.5 No No
6 empty 1.78 66.1 7.8 No No
7 empty 2.29 57.7 18.4 No No
8 empty 1.22 97.7 0 Yes No
9 empty 2.25 68.9 9.9 No No
10 empty 2.45 72.3 7.6 No No
3UMW_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 72.8 41.8 Yes Yes
2 empty 2.11 66.4 51.9 No No
3 bound 1.95 68.2 16.4 No No
4 empty 2.28 69.8 11.9 No No
5 empty 2.48 68 14.7 No No
6 empty 2.33 61.4 13.7 No No
7 empty 2.62 63.6 14.9 No No
8 empty 2.43 59.7 16.6 No No
9 empty 2.18 62.1 10.4 No No
10 empty 1.19 98 0 Yes No
3CXW_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 72.8 40.8 Yes Yes
2 empty 2.45 65.4 32.5 No No
3 empty 2.17 67.5 14.5 No No
4 empty 2.15 61.7 12 No No
5 empty 1.82 69.8 11.7 No No
6 empty 1.94 69.2 15.9 No No
7 empty 2.45 65.8 11.7 No No
8 empty 1.59 58.3 13.2 No No
9 empty 2.03 65.4 14.3 No No
10 empty 2.27 63.2 17.5 No No
4N6Y_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 74 38.1 Yes Yes
2 empty 2.43 65.7 33.7 No No
3 empty 2.33 63.8 19 No No
4 empty 2.29 66.3 21.4 No No
5 empty 1.98 58.8 15.3 No No
6 empty 1.49 68.3 11.2 No No
7 empty 2.33 61.7 12.8 No No
8 empty 2.55 64 11.8 No No
9 empty 2.13 66.8 12.4 No No
10 empty 1.58 56.3 12.3 No No
5KZI_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 72.9 41.8 Yes Yes
2 empty 2.39 69.4 30.1 No No
3 empty 2.6 72.1 19 No No
4 empty 1.94 65.6 16.1 No No
5 empty 1.59 70.1 12 No No
6 empty 2.58 60.8 13.9 No No
7 empty 2.49 66.6 18.4 No No
8 empty 1.92 57 16.6 No No
9 empty 2.46 61.6 13.2 No No
10 empty 1.72 57.8 11.8 No No
1YXT_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 72.1 30.7 Yes Yes
2 empty 2.32 66.1 34.1 No No
3 empty 2.32 65.1 18.3 No No
4 empty 2.06 68.4 16.7 No No
5 empty 2.19 58.2 20.7 No No
6 empty 2.5 67.2 17.5 No No
7 empty 2.41 61 15.6 No No
8 empty 1.56 72.3 11.3 No No
9 empty 2.86 61.4 15.1 No No
10 empty 2.29 70.5 13.7 No No
5KGI_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 74.2 41.4 Yes Yes
2 bound 2.43 66.6 29.8 No No
3 bound 2.35 64 29.3 No No
4 empty 2.28 66.8 18.1 No No
5 bound 2.53 63.2 14.9 No No
6 empty 1.61 72.7 11.7 No No
7 empty 2.02 66.3 12.3 No No
8 empty 2.55 64.1 12.3 No No
9 empty 2.07 57.8 18.6 No No
10 bound 2.1 69.7 9.4 No No
5N4O_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 73 36.4 Yes Yes
2 empty 2.54 65.9 34.8 No No
3 empty 2.12 65.1 29 No No
4 empty 2.19 66 17.8 No No
5 empty 1.51 59.3 17.5 No No
6 empty 1.94 71.9 13.9 No No
7 empty 2.43 62.1 12.2 No No
8 empty 1.78 61.8 10.8 No No
9 empty 2.13 61.3 13.3 No No
10 empty 1.89 58.2 10.1 No No
4MBI_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.33 64.3 52.8 Yes No
2 bound 1.99 74.8 40.9 No No
3 empty 2.28 65 20.5 No No
4 empty 2.23 58.9 19.8 No No
5 empty 2.6 58.9 19.9 No No
6 empty 2.64 65.6 16.8 No No
7 empty 2.11 68.1 13.6 No No
8 empty 1.79 62.3 17.6 No No
9 empty 2.43 71.9 12.8 No No
10 empty 2.21 67.6 9.3 No No
4JX3_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 75.3 37.8 Yes Yes
2 empty 2.61 65.9 32.6 No No
3 empty 2.41 65.9 17 No No
4 empty 2.5 60.4 18.9 No No
5 empty 2.25 60.2 20.6 No No
6 empty 2.12 67.8 15.6 No No
7 empty 2.54 64.5 12.9 No No
8 empty 1.52 73.4 11.2 No No
9 empty 2.45 64.6 10.7 No No
10 empty 1.98 64.5 10.1 No No
2XIZ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 71.8 41.9 Yes Yes
2 empty 2.57 68 35.8 No No
3 empty 2.22 65 14.9 No No
4 empty 2.12 67 18.5 No No
5 empty 2.54 66.3 13.1 No No
6 empty 2.39 62.9 22.1 No No
7 empty 1.65 69.7 10.5 No No
8 empty 2.55 64.8 12.5 No No
9 empty 1.97 51.1 16.2 No No
10 empty 2.45 64.8 10.2 No No
3CY2_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 76.5 34.6 Yes Yes
2 bound 2.41 65.5 38.6 No No
3 empty 2.04 69.7 19.1 No No
4 empty 2.13 69 15.8 No No
5 empty 1.96 71.2 12.9 No No
6 empty 2.35 64.5 9.5 No No
7 empty 1.54 58.7 12.6 No No
8 empty 2.05 66.9 12.7 No No
9 empty 2.32 60.3 13.5 No No
10 empty 2.69 64.1 11.7 No No
4ALV_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.31 67.5 35.4 Yes No
2 bound 1.62 77.1 23.3 Yes No
3 empty 2.43 76.7 18 No No
4 empty 2.27 63.2 15.8 No No
5 bound 2.34 63.8 20.2 No No
6 empty 2.48 66.3 15.7 No No
7 empty 1.65 71.6 10.9 No No
8 empty 2.2 63.9 14.2 No No
9 empty 1.79 60.1 15.1 No No
10 empty 2.51 61.5 13.4 No No
3MA3_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 72.8 38.8 Yes Yes
2 empty 2.21 67.5 28.9 No No
3 empty 2.3 65.3 35.4 No No
4 empty 2.13 63.5 22.3 No No
5 empty 2.26 70.5 11.8 No No
6 empty 1.94 72.1 14.4 No No
7 empty 2.21 61.2 11.2 No No
8 empty 2.19 65.2 14 No No
9 empty 1 98.6 0 Yes No
10 empty 2.48 65 7.7 No No
5VUB_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 74.5 39.7 Yes Yes
2 empty 2.31 65.3 26.2 No No
3 empty 2.35 64.7 34.5 No No
4 empty 2.34 74 13.8 No No
5 empty 2.31 65.3 19.2 No No
6 bound 1.87 66.7 17.6 No No
7 empty 2.6 58.6 14.5 No No
8 empty 2.01 58.4 17.3 No No
9 empty 1.92 70.4 9.2 No No
10 empty 2.47 59.5 15 No No
6PDO_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 73.1 33.2 Yes Yes
2 empty 2.32 65.8 34.4 No No
3 empty 2.19 62.5 17.9 No No
4 empty 2.36 63.1 21.4 No No
5 empty 1.74 71.6 10.6 No No
6 empty 2.25 69.5 14 No No
7 empty 2.5 59.3 13.8 No No
8 empty 2.42 77.1 15.1 No No
9 empty 1.86 67 13.3 No No
10 empty 1.79 66.8 11.4 No No
5DGZ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 76.6 31 Yes Yes
2 empty 2.52 67.5 32.5 No No
3 empty 2.28 63.2 24.7 No No
4 empty 2.23 70 28 No No
5 empty 1.64 69.8 13 No No
6 empty 2.49 63.1 14 No No
7 empty 1.68 61.6 17.8 No No
8 empty 2.26 67.5 11.2 No No
9 empty 2.73 63.2 11.1 No No
10 empty 2.4 63.2 9.8 No No
5TEX_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 73.1 33.6 Yes Yes
2 empty 2.47 67.3 34.1 No No
3 empty 2.23 62.5 19.1 No No
4 bound 2.45 70.2 19.8 No No
5 empty 2.62 65.5 15.5 No No
6 empty 2.39 59.8 13.8 No No
7 empty 1.55 71.6 10.7 No No
8 empty 2.09 69.3 13 No No
9 empty 1.79 61.4 16.2 No No
10 empty 2.11 58.4 16 No No
5TEL_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 76.3 37.3 Yes Yes
2 empty 2.34 64.2 33.6 No No
3 empty 2.22 65.1 16.5 No No
4 bound 2.34 68.1 18.5 No No
5 empty 1.8 67.4 15.7 No No
6 empty 1.6 74.6 11.7 No No
7 empty 2.57 66.8 13.9 No No
8 empty 2.58 61.1 13.5 No No
9 empty 2.26 61.6 11.1 No No
10 empty 2.56 64.8 15.3 No No
1YXV_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 75.1 33.6 Yes Yes
2 empty 2.44 65.7 36.1 No No
3 empty 2.24 64.1 19.8 No No
4 bound 2.23 69.8 15.7 No No
5 empty 2.38 65.2 12.2 No No
6 empty 2.69 59.5 14.2 No No
7 empty 1.61 70 11.5 No No
8 empty 2.33 61.7 14.5 No No
9 empty 2.2 82.5 12.7 No No
10 empty 2.07 58.7 17.6 No No
5N4U_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 72.9 36.1 Yes Yes
2 empty 2.25 67.3 26.7 No No
3 empty 2.5 68.9 33.2 No No
4 empty 2.46 54.9 14.1 No No
5 empty 1.44 57.6 14.7 No No
6 empty 2.48 67.7 12.1 No No
7 empty 2.12 82.1 12.3 No No
8 empty 1.84 67 9.4 No No
9 empty 2.06 72.8 9.3 No No
10 empty 2.18 66.1 10.4 No No
5KGG_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.42 72.2 31.9 Yes Yes
2 bound 2.51 63.5 34.5 No No
3 bound 2.24 60.8 21.2 No No
4 bound 2.2 61.7 16.6 No No
5 empty 1.59 67.2 13.3 No No
6 bound 2.41 59.8 12.1 No No
7 bound 2.16 62.7 14.1 No No
8 empty 2.45 60.7 12.6 No No
9 empty 2.48 65.4 12.1 No No
10 empty 1.93 57 12.1 No No
3R01_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 73.9 39.1 Yes Yes
2 empty 2.47 66.1 33.6 No No
3 empty 2.4 63.1 17.6 No No
4 empty 2.67 57.1 21.4 No No
5 empty 2.01 59.2 17.2 No No
6 bound 2.06 70 12.7 No No
7 empty 2.68 58.2 13.7 No No
8 empty 1.53 71.4 15.7 No No
9 empty 2.58 68 18.7 No No
10 empty 1.87 66.5 7.4 No No
4A7C_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 71.4 38.8 Yes Yes
2 empty 2.27 68.9 25 No No
3 bound 2.49 64.7 33.5 No No
4 bound 2.22 67.1 25.6 No No
5 empty 2.02 54.7 17.4 No No
6 empty 2.37 61.4 11.1 No No
7 empty 1.86 64.9 9.6 No No
8 empty 2.25 62.8 9.3 No No
9 empty 2.3 58.4 11 No No
10 empty 1.27 97.1 0 Yes No
6AYD_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 67.9 34.2 Yes No
2 empty 2.2 66.3 35.6 No No
3 empty 2.23 67.2 34.4 No No
4 bound 1.92 78 24.2 No No
5 empty 2.21 63.9 28.3 No No
6 empty 2.04 65.1 23.1 No No
7 empty 2.28 64 9.8 No No
8 empty .79 99.5 0 Yes No
9 empty 2.21 59.5 9.1 No No
10 empty 2.14 59.4 9.2 No No
3VBT_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.39 70.2 40.1 Yes Yes
2 empty 2.56 64.3 34.9 No No
3 empty 2.2 65.3 16.9 No No
4 empty 1.91 68.2 14.5 No No
5 empty 1.88 65.3 16.9 No No
6 empty 2.12 63.9 14.4 No No
7 empty 2.52 66.4 16.8 No No
8 empty 1.88 73.1 14.5 No No
9 empty 2.44 62.2 11.1 No No
10 empty 2.51 66.7 10.3 No No
2XJ2_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 73.6 38.1 Yes Yes
2 empty 2.48 69.1 33.8 No No
3 empty 2.35 64 20.2 No No
4 empty 1.93 70.5 12.3 No No
5 empty 2.24 59.2 14 No No
6 empty 1.72 68.7 13.1 No No
7 empty 2.49 65.9 10.4 No No
8 empty 2.56 67.9 16.8 No No
9 empty 2.55 62.3 12.4 No No
10 empty 1.89 55.7 17.2 No No
4K18_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 70.5 35.8 Yes No
2 bound 1.77 76.6 22.6 No No
3 empty 2.43 67.3 33.4 No No
4 empty 2.48 64.2 30.6 No No
5 empty 2.32 64.9 25 No No
6 empty 2.26 66.2 17.3 No No
7 empty 2.1 55.4 20.1 No No
8 empty 1.49 68.8 12 No No
9 empty 2.04 62.5 22.4 No No
10 empty 2.3 61.8 12.4 No No
4IAA_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 77.5 32.4 Yes Yes
2 empty 2.37 65.1 40.2 No No
3 empty 2.29 69.7 21.1 No No
4 empty 2.26 65.5 24.9 No No
5 empty 2.22 62.6 20.8 No No
6 empty 2.33 64.1 10.2 No No
7 empty 2.36 63 15.3 No No
8 empty 2.55 68.3 10.3 No No
9 empty 1.99 64.6 9.3 No No
10 empty 2.28 58.6 13.4 No No
3BGP_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 75 32.4 Yes Yes
2 empty 2.42 65.3 35.8 No No
3 empty 2.25 65 27.4 No No
4 empty 2.39 62.4 19.1 No No
5 empty 1.65 71.3 11.8 No No
6 empty 2.15 67.8 14.5 No No
7 empty 2.44 61.9 13.5 No No
8 empty 1.86 60.1 16.1 No No
9 empty 1.93 47.6 16.2 No No
10 empty 1.19 98 0 Yes No
2J2I_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 71 41.3 Yes Yes
2 empty 2.23 67.6 27.4 No No
3 bound 2.46 65.8 34.6 No No
4 empty 2.19 65.5 27 No No
5 empty 1.91 65.8 18.3 No No
6 empty 2.49 58.7 13.6 No No
7 empty 2.12 76.2 11.7 No No
8 empty 1.85 60.8 10.6 No No
9 empty 2.26 61.3 11.2 No No
10 empty 1.96 65 8.8 No No
4RC2_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 74.5 37.3 Yes No
2 empty 2.28 66.7 28 No No
3 empty 2.53 64.7 33.4 No No
4 empty 2.14 68.6 23.6 No No
5 empty 2.26 62.4 23.8 No No
6 empty 2.39 61.7 12.2 No No
7 empty 2.25 62.1 10.8 No No
8 empty 2.06 67.1 8.6 No No
9 empty 2.14 59.5 10.7 No No
10 empty 1.91 64.4 11.6 No No
4WRS_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 73.9 38.3 Yes Yes
2 empty 2.51 67.1 30.6 No No
3 empty 2.31 63.7 28.2 No No
4 bound 2.54 66.1 23.8 No No
5 empty 1.62 71.3 12.1 No No
6 empty 2.38 62.9 21.6 No No
7 empty 2.48 61.7 12 No No
8 empty 2.52 62.2 11.1 No No
9 empty 1.79 57 16.6 No No
10 empty 1.82 65.3 9.6 No No
3VBQ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 72.3 40 Yes Yes
2 empty 2.4 63.3 34 No No
3 empty 2.56 66.5 20.7 No No
4 empty 2.04 67.9 14.8 No No
5 empty 2.41 67.2 13.5 No No
6 empty 2.06 68 16.7 No No
7 empty 1.55 72.6 14.1 No No
8 empty 2.37 61.2 15.8 No No
9 empty 2.5 63.9 10.7 No No
10 empty 1.73 58.4 16.6 No No
4N6Z_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 69 31.8 Yes Yes
2 empty 2.2 63.1 22.6 No No
3 empty 2.14 64.6 15.6 No No
4 empty 2.22 54.6 17.8 No No
5 empty 1.65 64.7 14.1 No No
6 empty 2.47 59.3 11.8 No No
7 empty 1.52 51.6 14.9 No No
8 empty 1.91 68.9 10.2 No No
9 bound 1.71 69 9.6 No No
10 empty 1.85 64.4 9.4 No No
6PDN_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 70.1 38.9 Yes Yes
2 empty 2.44 65.8 33 No No
3 empty 2.37 66.5 16.5 No No
4 empty 1.52 72.7 15.3 No No
5 empty 1.97 68.6 12.4 No No
6 empty 2.17 68.3 15.2 No No
7 empty 1.99 57.6 15.7 No No
8 empty 2.39 62.2 13.2 No No
9 empty 2.24 62.8 14.1 No No
10 empty 1.69 64.3 14 No No
1YWV_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 72.5 40.6 Yes Yes
2 empty 2.43 67.3 31.1 No No
3 empty 2.23 62.1 17.2 No No
4 bound 2.19 63.1 20.6 No No
5 empty 2.47 66.2 18.4 No No
6 empty 1.6 69.9 11.3 No No
7 empty 2.36 63 14.2 No No
8 empty 2.5 60.8 13 No No
9 empty 1.82 58.5 16.8 No No
10 empty 2.26 56.6 17.5 No No
4ENY_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 72.8 40.3 Yes Yes
2 empty 2.35 65.4 35.4 No No
3 empty 2.29 63.5 18.8 No No
4 bound 2.11 69.8 15.5 No No
5 empty 1.65 68.6 10.5 No No
6 empty 2.45 59.1 12.3 No No
7 empty 2.59 66.3 15.4 No No
8 empty 2.12 70 10.2 No No
9 empty 2.82 64.4 9.7 No No
10 empty 1.04 100 0 Yes No
2BZI_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 72.7 37.1 Yes Yes
2 empty 2.24 65.1 38.9 No No
3 empty 2.49 66.8 32.7 No No
4 empty 2.34 63.5 24.2 No No
5 empty 2.39 61.2 11.4 No No
6 empty 2.14 62.2 15.8 No No
7 empty 1.78 52.8 11.5 No No
8 empty 2.14 62.5 10.9 No No
9 empty 2.26 59 11.8 No No
10 empty 2.1 71.7 10 No No
4GW8_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 73 35.6 Yes Yes
2 empty 2.15 65.6 35.5 No No
3 empty 2.57 66.9 32.4 No No
4 empty 2.46 66.8 19.1 No No
5 empty 2.22 70.5 18 No No
6 empty 2.5 60.5 12 No No
7 empty 1.84 64.3 11.7 No No
8 empty .75 97.5 0 Yes No
9 empty 2.69 65.6 9.5 No No
10 empty 2.32 61.9 9.7 No No
5N52_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 70.6 38.6 Yes Yes
2 empty 2.18 68.4 23.6 No No
3 empty 2.43 66.9 32.1 No No
4 empty 2.5 60.6 12.8 No No
5 empty 1.94 69 16.6 No No
6 empty 1.26 52.9 15 No No
7 empty 2.17 71.6 12.1 No No
8 empty 2.01 78.2 11.8 No No
9 empty 1.6 61.5 12.5 No No
10 empty 1.76 51.4 12.3 No No
3DCV_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 75.3 31.5 Yes No
2 empty 2.53 67.5 34.7 No No
3 empty 2.35 69.6 20 No No
4 empty 2.1 67.7 18.1 No No
5 empty 1.62 70.7 13.7 No No
6 empty 2.39 65.1 15.7 No No
7 empty 2.45 65.7 13.1 No No
8 empty 2.46 57.4 14.3 No No
9 empty 2.14 53 17.5 No No
10 empty 2.24 64.5 11.7 No No
5TOE_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 74.1 38.5 Yes Yes
2 empty 2.26 63.5 34.2 No No
3 empty 2.49 63.1 36.2 No No
4 empty 2.47 56.5 17.1 No No
5 empty 2.38 65.3 20.8 No No
6 empty 2.59 64 16.4 No No
7 empty 2.72 68.6 13.3 No No
8 empty 1.98 72.2 15.8 No No
9 empty 2.41 60.1 13.9 No No
10 empty 2.08 58.6 17.9 No No
4AS0_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 74.7 38.5 Yes Yes
2 empty 2.46 65.6 32.7 No No
3 empty 2.38 67.5 16.4 No No
4 empty 2.36 66.5 23.5 No No
5 empty 1.52 73.5 11.4 No No
6 empty 1.95 59.7 18.1 No No
7 empty 2.5 63.6 10.1 No No
8 empty 2.74 64.7 13.8 No No
9 empty 1.98 54.4 14.8 No No
10 empty 1.9 83.8 11.2 No No
2O3P_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 74.4 39.1 Yes Yes
2 empty 2.52 66.2 35.6 No No
3 empty 2.33 64.6 16.3 No No
4 empty 2.13 64.3 19.5 No No
5 bound 1.98 68.4 17.1 No No
6 empty 2.12 58.6 24.7 No No
7 empty 1.48 72.1 11.6 No No
8 empty 2.48 66.7 15.1 No No
9 empty 2.21 60.2 12.8 No No
10 empty 2.47 58.4 13.2 No No
2BZH_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 71.5 41.7 Yes Yes
2 empty 2.25 66.5 37.3 No No
3 empty 2.49 66.7 33.5 No No
4 empty 1.99 65.5 26.6 No No
5 empty 2.23 62.5 12.2 No No
6 empty 1.87 56.3 15.6 No No
7 empty 2.44 64.9 11 No No
8 empty 2.06 77.6 9.9 No No
9 empty 2.19 66.7 10.7 No No
10 empty 1.21 97.6 0 Yes No
5N4R_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 73.4 37.4 Yes Yes
2 empty 2.14 65.7 33.6 No No
3 empty 2.41 65 33.7 No No
4 empty 2.59 59.4 13.7 No No
5 empty 1.69 62 16.2 No No
6 empty 1.93 70.1 16.4 No No
7 bound 2.28 72.8 12.5 No No
8 empty 1.86 71.5 8.1 No No
9 empty 2.21 58.3 19.2 No No
10 empty 1.93 81.4 10.5 No No
4MTA_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 75.3 37.9 Yes Yes
2 empty 2.49 67 32.7 No No
3 empty 2.36 63.3 20.6 No No
4 empty 2.17 65.9 15.1 No No
5 empty 2.5 66.9 16.4 No No
6 empty 1.68 72.3 11.1 No No
7 empty 2.47 62.3 11.8 No No
8 empty 1.79 60.7 14.5 No No
9 empty 2.46 61.5 18.5 No No
10 empty 2.48 61.6 15 No No
5N4Y_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 74.1 39 Yes Yes
2 empty 2.07 66.7 24.5 No No
3 empty 2.46 65.8 33 No No
4 empty 2.61 57.7 15.2 No No
5 empty 1.97 69.2 14.2 No No
6 empty 1.38 58.4 15.5 No No
7 empty 1.79 67.4 9.3 No No
8 empty 2.41 61.5 11.7 No No
9 empty 1.91 66.3 11.9 No No
10 empty 1.91 82.2 10.3 No No
5N4X_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 73.5 37.9 Yes Yes
2 empty 2.19 67.4 30.8 No No
3 empty 2.5 65.5 34.8 No No
4 empty 1.96 71 16.8 No No
5 empty 2.5 60.2 14 No No
6 empty 1.58 55.6 14.1 No No
7 empty 1.62 65.7 9 No No
8 empty 2.03 69 10.4 No No
9 empty 2.42 60.3 11.5 No No
10 empty 2.12 63.4 9.1 No No
3BGZ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 75.8 39.7 Yes Yes
2 empty 2.49 65.5 41 No No
3 empty 2.39 65.7 17.6 No No
4 empty 2.11 66.4 20.2 No No
5 empty 1.61 72.1 11.5 No No
6 empty 2.5 67.5 18.4 No No
7 empty 2.43 61.7 12.8 No No
8 empty 1.84 67.6 10 No No
9 empty 1.91 55.7 10.1 No No
10 empty 2.8 68.4 9.4 No No
6PDP_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 72.4 34.4 Yes Yes
2 bound 2.67 69 34.4 No No
3 empty 2.36 67.8 15.6 No No
4 empty 1.39 70.5 14.1 No No
5 empty 1.63 56.4 17.6 No No
6 empty 2.51 65.3 12.3 No No
7 empty 1.86 71.1 8.2 No No
8 empty 1.93 69.3 10.5 No No
9 empty 1.94 64.7 11.1 No No
10 empty 2.75 68 8.3 No No
5DHJ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 75.2 39.1 Yes Yes
2 empty 2.55 67.7 34.9 No No
3 empty 2.21 63.4 25.4 No No
4 empty 2.61 65.9 18.7 No No
5 empty 2.27 64.5 21.4 No No
6 empty 1.61 68.9 14.9 No No
7 empty 2.46 61.6 13.2 No No
8 empty 1.83 62.5 16.3 No No
9 empty 2.1 69 10.4 No No
10 empty 2.42 61.2 12 No No
3C4E_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 76.1 37.2 Yes Yes
2 empty 2.51 63.9 37.9 No No
3 empty 2.3 65.3 20 No No
4 empty 2.38 61.4 28 No No
5 bound 2.1 70 16.7 No No
6 empty 2.48 65.6 18.6 No No
7 empty 1.59 69.3 11.2 No No
8 empty 2.38 60.6 13.2 No No
9 empty 2.66 65.7 12.9 No No
10 empty 1.98 63.6 14.8 No No
1YXU_D Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 75.1 40.8 Yes Yes
2 empty 2.49 64.5 35 No No
3 empty 2.26 65.5 18.3 No No
4 bound 2.11 68.5 18.1 No No
5 empty 1.65 72.3 13.2 No No
6 empty 2.42 62.7 16.1 No No
7 empty 2.71 64.8 15.2 No No
8 empty 2.54 60.9 11.8 No No
9 empty 2.43 61 12.3 No No
10 empty 1.79 53.8 14.8 No No
3BGQ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 76.7 32.9 Yes Yes
2 empty 2.37 63.2 41.7 No No
3 empty 2.49 64.8 19.1 No No
4 empty 2.3 67.7 19.9 No No
5 empty 2.8 61.2 19.2 No No
6 empty 1.7 72.1 12.1 No No
7 empty 2.45 67.5 17.5 No No
8 empty 1.71 56.7 16.4 No No
9 empty 2.43 67.8 10.7 No No
10 empty 2.26 64.3 17.1 No No
3JYA_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 70.7 40.1 Yes Yes
2 empty 2.35 64.4 31.4 No No
3 empty 2.27 65.3 17.4 No No
4 empty 2.17 57.3 23.5 No No
5 empty 2.51 63 16.4 No No
6 empty 1.95 64.8 16.7 No No
7 empty 1.62 71.8 10.5 No No
8 empty 2.6 57.7 13.8 No No
9 empty 2.38 61.3 12.9 No No
10 empty 2.01 58.1 16.8 No No
5V80_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 73.4 32.4 Yes Yes
2 empty 2.26 64.6 29.7 No No
3 bound 2.54 67.2 33.5 No No
4 empty 2.11 66.4 26.5 No No
5 empty 2.5 59.4 13.7 No No
6 empty 1.72 59.7 14.8 No No
7 empty 1.91 70.7 8 No No
8 empty 2.48 62.9 11.2 No No
9 empty 2.15 68.6 8 No No
10 empty 1.86 59.2 9.4 No No
3R04_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 71.3 35.1 Yes Yes
2 empty 2.33 62.3 27.5 No No
3 empty 2.27 62.2 19.2 No No
4 empty 1.94 63.2 12.1 No No
5 empty 1.57 67.1 12.6 No No
6 empty 2.49 61.2 16 No No
7 empty 2.48 59.4 14.4 No No
8 empty 2.41 58.9 14.2 No No
9 empty 1.65 55.9 14.6 No No
10 empty 2.43 68.8 12 No No
6QXK_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 68.8 39.3 Yes Yes
2 empty 2.16 68.5 25.3 No No
3 empty 2.44 66.1 35.3 No No
4 empty 1.98 60.7 23.9 No No
5 empty 2.39 67.3 17.9 No No
6 empty 1.93 66.6 13 No No
7 empty 2.58 61.6 10.9 No No
8 empty 1.91 74.9 12.3 No No
9 empty 1.84 64.9 10.5 No No
10 empty 2.44 60.3 9.8 No No
2O64_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 76.8 32.7 Yes Yes
2 empty 2.28 66 33.3 No No
3 empty 2.36 63 17.4 No No
4 empty 2.36 69.2 23.1 No No
5 bound 2.15 67.6 14.9 No No
6 empty 2.51 65.4 13.7 No No
7 empty 1.98 55.7 16.9 No No
8 empty 1.5 71.2 11.4 No No
9 empty 2.29 64.3 11.2 No No
10 empty 2.06 60.3 13.7 No No
3UMX_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 64.9 52.8 Yes No
2 bound 2.09 71.8 41.4 No No
3 empty 1.92 66.7 15.8 No No
4 empty 2.53 58.1 15.5 No No
5 empty 2.54 64.5 16.7 No No
6 empty 2.11 72.1 10.1 No No
7 empty 2.59 67.6 10 No No
8 empty 2.43 65.5 13.8 No No
9 empty 2.37 63.7 10 No No
10 empty 2.47 74.6 7.3 No No
5MZL_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 70.8 36.9 Yes Yes
2 empty 2.16 65.3 27.2 No No
3 empty 2.44 66.6 33.8 No No
4 empty 1.93 70.8 14.6 No No
5 empty 2.37 61.7 13.2 No No
6 bound 1.92 65.3 14.7 No No
7 empty 1.66 61.4 12.6 No No
8 empty 2.13 67.4 7.9 No No
9 empty 1.83 56.7 12.4 No No
10 empty 2.13 61.8 13.3 No No
1YI3_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 69.3 43.6 Yes Yes
2 empty 2.51 66.3 32.7 No No
3 empty 2.25 66.9 26.2 No No
4 empty 2.51 59.4 14.2 No No
5 empty 2.71 66.1 13.4 No No
6 empty 2.62 59.8 13.1 No No
7 empty 2.02 54.6 11.4 No No
8 empty 2.24 59.4 15.3 No No
9 empty 2.82 64.4 16.1 No No
10 empty 1.22 99.5 0 Yes No
4ENX_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 72.7 45.1 Yes Yes
2 empty 2.41 66.3 36.4 No No
3 empty 2.34 63.3 22 No No
4 empty 1.96 65.7 17.1 No No
5 empty 2.46 60.4 12.3 No No
6 empty 2.67 65.4 18.8 No No
7 empty 1.69 70.4 10.6 No No
8 empty 2.17 70.4 11.4 No No
9 empty 2.42 62.9 14.4 No No
10 empty .85 96 0 Yes No
3JPV_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 76.9 35.1 Yes Yes
2 empty 2.3 65.5 33.8 No No
3 empty 2.16 69.5 24.7 No No
4 empty 1.94 69.9 16 No No
5 empty 2.31 66.6 13.3 No No
6 empty 2.57 64.9 10.5 No No
7 empty 1.73 61.3 17.7 No No
8 empty 2.73 65.2 16.1 No No
9 empty 1.98 66.1 13 No No
10 empty 2.31 69.7 7.6 No No
4MBL_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 64.9 51.6 Yes No
2 bound 2.01 76.1 31.2 No No
3 empty 2.09 55.5 20.5 No No
4 empty 2.36 66.9 19.5 No No
5 empty 2.57 55.2 18.7 No No
6 empty 2.34 68.1 14.3 No No
7 empty 2.52 59.2 13.6 No No
8 empty 1.75 55.7 16.9 No No
9 empty 2.59 61.4 10.9 No No
10 empty 1.81 66.5 7.6 No No
3VBV_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 73.4 41.5 Yes Yes
2 empty 2.32 64.5 34 No No
3 empty 2.33 61.5 18 No No
4 empty 2.06 67.1 15.2 No No
5 empty 2.41 61.5 16.8 No No
6 empty 1.5 70.9 14.9 No No
7 empty 2.48 62.5 14.7 No No
8 empty 2.52 64.8 15.7 No No
9 empty 2.46 59.4 13.1 No No
10 empty 2.09 67.5 14.9 No No
5N5M_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 73 35.8 Yes Yes
2 empty 2.22 66.5 23.7 No No
3 empty 2.4 65.9 32.3 No No
4 empty 1.41 61.6 16.8 No No
5 empty 1.88 69 14.9 No No
6 empty 2.23 69.1 12 No No
7 empty 2.5 60.6 10.7 No No
8 empty 1.65 67.3 9.6 No No
9 empty 1.92 51.3 11.5 No No
10 empty 1.2 99 0 Yes No
4BZN_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 75.4 33 Yes Yes
2 empty 2.38 66.6 37.2 No No
3 empty 2.29 64.9 26.1 No No
4 empty 2.23 63.8 17.4 No No
5 empty 1.64 68.5 10.4 No No
6 empty 2.59 60.9 14.2 No No
7 empty 2.18 59.2 17.1 No No
8 empty 2.58 65.1 12.7 No No
9 empty 1.78 69.8 8.9 No No
10 empty 1.88 58.8 13.9 No No
6NO9_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 71.2 39 Yes Yes
2 empty 2.29 65.8 32.6 No No
3 bound 2.18 64.2 27.1 No No
4 empty 2.42 61.7 16.3 No No
5 empty 1.54 69.9 12.2 No No
6 empty 2.54 61.4 10.9 No No
7 empty 1.67 62.5 11.3 No No
8 empty 2.37 62.3 14.4 No No
9 empty 1.88 82 10.4 No No
10 empty 2.26 63.9 9.1 No No
6PDI_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 73.9 33 Yes Yes
2 empty 2.19 67.2 27.3 No No
3 empty 2.47 67.6 33.8 No No
4 bound 2.22 59.1 21 No No
5 empty 2.04 63.4 21.3 No No
6 empty 2.39 66.9 12.5 No No
7 empty 1.94 69.7 14.4 No No
8 bound 2.5 57.2 13.8 No No
9 empty 2.19 63.6 13.5 No No
10 bound 1.86 59.8 14 No No
4WT6_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 74.2 38 Yes Yes
2 empty 2.45 68.2 32.3 No No
3 empty 2.36 68.1 15.5 No No
4 empty 1.93 66.3 15.3 No No
5 empty 1.64 71.6 12.5 No No
6 empty 2.56 67.1 16.3 No No
7 empty 2.61 59.1 12.8 No No
8 empty 2.57 62.9 15.3 No No
9 empty 1.92 62.1 16.4 No No
10 empty 1.8 67.4 9.7 No No
5N50_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 74.7 36.2 Yes Yes
2 empty 2.19 66.6 25.6 No No
3 empty 2.52 67.3 30.7 No No
4 empty 1.92 69.1 17.1 No No
5 empty 2.61 61.7 12.5 No No
6 empty 1.4 58.3 17.2 No No
7 empty 2.33 68.4 14.5 No No
8 empty 1.84 65.7 12.8 No No
9 empty 2.27 59.3 10 No No
10 empty 1.81 51.4 11.1 No No
4TY1_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 74.5 30 Yes Yes
2 empty 2.45 69.2 32.6 No No
3 bound 2.06 64.9 15.5 No No
4 empty 2.01 67.1 17.1 No No
5 empty 1.61 70.7 10.6 No No
6 empty 2.34 65.1 12.6 No No
7 empty 2.43 64.9 17 No No
8 empty 2.36 62.8 11.9 No No
9 empty 1.82 62.7 16.8 No No
10 empty 1.93 69.3 12.3 No No
5IIS_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 74.9 33.1 Yes Yes
2 empty 2.35 64.7 34 No No
3 empty 2.35 64.3 16.5 No No
4 empty 2.13 56.2 16.9 No No
5 bound 1.91 68.7 16.2 No No
6 empty 1.66 70.7 11 No No
7 empty 2.61 64.7 15.7 No No
8 empty 2.56 66.6 14.6 No No
9 empty 2.43 62.9 10.5 No No
10 empty 1.84 59.7 18 No No
2XJ0_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 72.5 32.3 Yes Yes
2 empty 2.7 67.7 32.3 No No
3 empty 2.3 66.9 18.7 No No
4 empty 1.88 69 15.3 No No
5 empty 2.2 63.9 13.6 No No
6 empty 2.34 68 16.9 No No
7 empty 1.55 73.9 11.6 No No
8 empty 2.33 62.2 11.2 No No
9 empty 1.88 55.1 13.2 No No
10 empty 2.05 64.8 12.7 No No
2BIL_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 71.9 39.7 Yes Yes
2 empty 2.12 63.9 32.1 No No
3 empty 2.45 63.5 33 No No
4 empty 2.07 65.1 22.8 No No
5 empty 2.26 66.7 15.3 No No
6 empty 2.48 66.7 15.8 No No
7 empty 2.52 65.9 15.9 No No
8 empty 2.2 58.8 19.3 No No
9 empty 2.3 63.5 9.3 No No
10 empty 1.8 52.3 10.9 No No
3VBW_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 72.2 40.2 Yes Yes
2 empty 2.23 64.6 38.1 No No
3 empty 2.39 65.4 33.8 No No
4 empty 2.45 59.3 18.9 No No
5 empty 1.87 69 14.5 No No
6 empty 2.44 67.6 18.7 No No
7 empty 2.55 61.1 14.3 No No
8 empty 2.15 70.9 14.6 No No
9 empty 2.17 68.2 8.8 No No
10 empty 2.11 76.4 8.9 No No
3UIX_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.41 66.2 52.2 Yes No
2 bound 2.23 71.3 41.7 No No
3 empty 2.49 67.8 18.4 No No
4 bound 2.23 66.3 16.1 No No
5 empty 2.57 65.7 18.8 No No
6 empty 2.5 59.1 13.6 No No
7 empty 2.36 69.7 11.8 No No
8 empty 2.34 70.5 8.4 No No
9 empty 1.96 58 14.2 No No
10 empty 1.19 96.3 0 Yes No
4I41_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 74.1 40 Yes Yes
2 empty 2.29 66.3 25.6 No No
3 empty 2.44 66.9 33.6 No No
4 bound 2.13 67.4 21.1 No No
5 empty 2.12 61.8 23 No No
6 empty 2.44 61.5 12.3 No No
7 empty 2.39 66.3 10.2 No No
8 empty 1.85 66.8 8.9 No No
9 empty 2.16 56.4 13.9 No No
10 empty 1.07 98.6 0 Yes No
1XWS_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 71 40.3 Yes Yes
2 empty 2.14 64.9 39 No No
3 empty 2.38 64.2 34.1 No No
4 empty 2.46 65.4 28.5 No No
5 empty 2.46 63.2 10.7 No No
6 empty 1.84 58.3 10.6 No No
7 empty 2.3 61.5 10.8 No No
8 empty 1.21 98.6 0 Yes No
9 empty 2.46 69.9 7.2 No No
10 empty 2.25 70.3 9 No No
4WSY_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 73.8 40.6 Yes Yes
2 empty 2.62 67.2 33.5 No No
3 empty 2.36 64.2 18.5 No No
4 empty 2.27 65.9 21.4 No No
5 empty 2.41 64.2 18.2 No No
6 empty 1.64 72.6 12.1 No No
7 empty 2.4 67.5 14.4 No No
8 empty 2.34 61.3 11.8 No No
9 empty 1.8 59 15.3 No No
10 empty 1.71 62.9 11.8 No No
4BZO_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 74.9 32 Yes Yes
2 empty 2.54 65.4 37.1 No No
3 empty 2.26 63.4 16.8 No No
4 empty 1.93 65.9 21.5 No No
5 empty 1.66 73.7 11.5 No No
6 empty 2.51 61.6 14 No No
7 empty 2.47 65.7 15.8 No No
8 empty 2.11 53.3 16.5 No No
9 empty 1.89 54 12.6 No No
10 empty 2.67 68.6 10 No No
5O13_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 71.4 41 Yes Yes
2 empty 2.43 65.4 33.4 No No
3 empty 2.22 64.7 23.5 No No
4 empty 2.25 64.5 17 No No
5 empty 1.57 72.1 10.8 No No
6 empty 1.84 69.4 15 No No
7 empty 1.92 59.6 17 No No
8 empty 2.37 62.3 9.6 No No
9 empty 1.79 55.2 11.3 No No
10 empty 2.32 64.5 7.1 No No
4JX7_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.42 66.4 52.9 Yes No
2 bound 2.02 75.7 38.2 No No
3 empty 2.53 55.8 18.4 No No
4 empty 2.28 60.7 22.1 No No
5 empty 2.53 64.3 11.3 No No
6 empty 2.23 67.5 16.8 No No
7 empty 2.58 67.9 11.9 No No
8 empty 2.53 65.4 11.9 No No
9 empty 1.89 67.5 9 No No
10 empty 2.02 57.8 16 No No
5DIA_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 75.8 40.6 Yes Yes
2 empty 2.57 67.7 33.9 No No
3 empty 2.25 64.1 25.5 No No
4 empty 2.17 59.7 19.5 No No
5 empty 1.61 73 14.8 No No
6 empty 2.45 63.8 15 No No
7 empty 2.47 62 13.2 No No
8 empty 1.7 60.6 14.7 No No
9 empty 2.22 62.2 10.5 No No
10 empty 1.85 59 10.5 No No
3VBX_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 74.1 40.3 Yes Yes
2 empty 2.68 64.5 33 No No
3 empty 2.32 65.6 17.1 No No
4 empty 2.41 62.2 16.9 No No
5 empty 1.92 67.5 17 No No
6 empty 1.47 71.2 11.3 No No
7 empty 2.53 65.9 18.6 No No
8 empty 2.52 60.9 10.3 No No
9 empty 2.2 54 13.2 No No
10 empty 2.43 66 11.4 No No
4LM5_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 76.7 32.4 Yes Yes
2 empty 2.22 65.5 28 No No
3 bound 2.3 65.6 34.8 No No
4 empty 2.53 61.3 29.2 No No
5 empty 2.52 68.9 24.9 No No
6 bound 2.1 69 16 No No
7 empty 2.45 61.5 12.4 No No
8 empty 2.39 77.4 11.7 No No
9 empty 1.91 69.5 9.1 No No
10 empty 2.16 70.1 7.8 No No
4LL5_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 75.4 40.8 Yes Yes
2 empty 2.32 66.8 25.5 No No
3 empty 2.41 63.8 34.2 No No
4 bound 2.26 66.7 25.9 No No
5 empty 2.34 64 13.3 No No
6 empty 2.51 64.2 12.1 No No
7 empty 2.44 69.8 8.8 No No
8 empty 2.24 64.9 8.4 No No
9 empty 2.36 60.3 9.6 No No
10 empty 1.06 98 0 Yes No
2OI4_X Serine/threonine-protein kinase pim-1 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 65.2 21.7 No No
2 bound 1.83 71 23.8 No No
3 empty 2.27 63.8 25.4 No No
4 bound 2.26 71.4 17.6 No No
5 empty 2.09 55.6 17.1 No No
6 empty 1.93 66.5 17.8 No No
7 bound 2.54 70.8 11.2 No No
8 empty 2.39 57.3 13.1 No No
9 empty 2.25 64.4 14 No No
10 empty 2.37 63.7 10.2 No No
5TUR_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 73.6 38 Yes Yes
2 empty 2.29 65.4 33.9 No No
3 empty 2.37 64.7 15.5 No No
4 empty 2.09 68.1 21.3 No No
5 empty 2.39 58 16.1 No No
6 empty 1.46 72.8 11.6 No No
7 empty 2.43 62.3 11.5 No No
8 empty 2.45 57 16.1 No No
9 empty 1.99 65 14.1 No No
10 empty 2.42 62.8 12.3 No No
3CY3_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 74.7 33.5 Yes Yes
2 empty 2.25 66.5 51.7 No No
3 empty 2.46 62 10.2 No No
4 empty 1.95 74.8 15.5 No No
5 empty 2.31 68 18.7 No No
6 empty 1.93 67.3 11.1 No No
7 empty 1.69 55.9 17 No No
8 empty 1.66 59.1 9.3 No No
9 empty 2.58 57.2 9.9 No No
10 empty 2.68 66.1 11.4 No No
2OBJ_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 75.2 28.9 Yes Yes
2 empty 2.33 63.1 42.8 No No
3 empty 2.02 65.5 21.9 No No
4 empty 2.05 72.2 18.5 No No
5 empty 2.48 69.1 18 No No
6 empty 2.16 70.2 16.5 No No
7 empty 2.28 60.1 10.9 No No
8 empty 1.96 57.2 11.9 No No
9 empty 2.45 67.8 11.6 No No
10 empty 2.29 69.8 10.7 No No
5VUA_B Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.28 65.2 52.3 Yes No
2 bound 1.92 75.3 38.2 No No
3 empty 2.16 69.3 13.1 No No
4 bound 2.27 67.6 21.5 No No
5 empty 2.57 66.2 17 No No
6 empty 1.89 57.6 18.2 No No
7 empty 2.27 57.1 10.6 No No
8 empty 2.05 71 8.3 No No
9 empty 2.53 59 14.9 No No
10 empty 2.58 62.6 10.7 No No
4RC4_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 74.3 39.7 Yes Yes
2 empty 2.25 67.3 29.3 No No
3 empty 2.44 66.6 31.1 No No
4 empty 2.12 63.2 21.3 No No
5 empty 2.58 69.4 15.9 No No
6 empty 2.18 67 14.9 No No
7 empty 2.34 60.5 13.2 No No
8 empty 2.56 64.5 14.5 No No
9 empty 1.73 67.5 8.5 No No
10 empty 1.96 66.2 12.6 No No
3VBY_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 73.1 36.1 Yes Yes
2 empty 2.28 65.4 27.6 No No
3 bound 2.41 64.7 32.9 No No
4 empty 2.18 70.4 13.7 No No
5 empty 2.44 66 15.3 No No
6 bound 2.24 67.1 16.5 No No
7 empty 2.59 65.9 16.6 No No
8 empty 2.56 60.6 13.9 No No
9 empty 1.96 71.8 14.1 No No
10 empty 2.18 58.6 15.4 No No
1YI4_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 72.1 37.6 Yes Yes
2 empty 2.52 65.1 37.9 No No
3 empty 2.25 61.7 18.6 No No
4 empty 2 68.6 17.3 No No
5 empty 2.26 68.8 18.9 No No
6 empty 1.47 71.3 10.9 No No
7 empty 2.25 58.4 12.7 No No
8 empty 2.11 61.9 16.5 No No
9 empty 1.89 54.3 12.4 No No
10 empty 2.34 61.6 9.7 No No
3C4E_D Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 75 38.3 Yes Yes
2 empty 2.45 63.4 37 No No
3 empty 2.3 62.6 22.8 No No
4 bound 1.96 70.7 11.4 No No
5 empty 1.64 72.2 13.8 No No
6 empty 2.4 69.2 17.2 No No
7 empty 2.57 57.5 13.8 No No
8 empty 2.13 61 17.5 No No
9 empty 2.55 65.1 13.1 No No
10 empty 1.84 62.9 12.1 No No
2C3I_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 72.4 41.5 Yes Yes
2 empty 2.17 68.1 26.4 No No
3 empty 2.32 63.5 33.1 No No
4 empty 2.28 65.9 13.5 No No
5 empty 2.22 67.4 13 No No
6 empty 2.59 65.2 12.5 No No
7 empty 2.07 72 9.1 No No
8 empty 2.35 66.5 10.2 No No
9 empty 2.44 67.7 10.2 No No
10 empty 2.39 62.9 7 No No
5KCX_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 73.9 34.2 Yes No
2 empty 2.26 66.1 31 No No
3 bound 2.49 64.5 33.3 No No
4 bound 1.93 69 14 No No
5 empty 2.53 60.1 18.7 No No
6 empty 2.43 64.2 16.9 No No
7 empty 2.36 62.8 13.3 No No
8 empty 2.01 57.1 15.1 No No
9 empty 1.74 64.9 8.1 No No
10 empty 2.51 68.2 9.1 No No
5N4V_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 76.5 35.2 Yes Yes
2 empty 2.54 66.3 34.1 No No
3 empty 1.91 66.1 28 No No
4 empty 2.31 72.7 15.7 No No
5 empty 1.93 72.4 17 No No
6 empty 2.59 56.7 13.8 No No
7 empty 1.53 57.4 14.2 No No
8 empty 2.26 67.5 13.4 No No
9 empty 1.99 67.3 9.4 No No
10 empty 1.91 55.7 8.5 No No
2XJ1_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 74.6 40 Yes Yes
2 empty 2.29 65.2 36.9 No No
3 empty 2.38 63.9 20.3 No No
4 empty 2.36 66 17.7 No No
5 empty 2.32 61.8 15.5 No No
6 empty 1.65 69.9 11.1 No No
7 empty 2.4 61.6 11 No No
8 empty 2.58 68 14.7 No No
9 empty 1.8 62.2 12.1 No No
10 empty 2.66 65.6 13.6 No No
3R02_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 70.2 34.3 Yes Yes
2 empty 2.22 61.3 20 No No
3 empty 2.12 68.9 16.5 No No
4 empty 2.21 59.8 19 No No
5 empty 2.67 61.5 16.7 No No
6 empty 1.59 67.4 12.2 No No
7 empty 1.99 63.7 13.4 No No
8 empty 2.48 58.1 13.7 No No
9 empty 1.75 56.6 15.4 No No
10 empty 2.29 64.1 11.3 No No
3T9I_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 68.8 41.3 Yes Yes
2 empty 2.59 68.9 33.3 No No
3 empty 2.37 63.1 17.2 No No
4 empty 2.58 65 18.7 No No
5 empty 2.33 66.5 20.5 No No
6 empty 1.47 68.3 11.8 No No
7 empty 2.27 57.5 15 No No
8 empty 2.31 60.4 14 No No
9 empty 1.63 63.4 15.7 No No
10 empty 1.17 97.7 0 Yes No
4RBL_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 74.3 42.6 Yes Yes
2 empty 2.25 67.6 29.3 No No
3 empty 2.43 67 32.1 No No
4 empty 2.19 63 17.6 No No
5 empty 2.27 63.5 17.1 No No
6 empty 2.55 70.5 18.7 No No
7 empty 2.2 71 11 No No
8 empty 2.39 63.3 12.4 No No
9 empty 2.66 66.2 10.8 No No
10 empty 2.16 61.2 10.9 No No
1YXU_C Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 73.8 40.5 Yes Yes
2 empty 2.32 64.7 38.1 No No
3 empty 2.35 67.8 17.5 No No
4 bound 2.03 72.7 16.9 No No
5 empty 1.64 72.8 11.5 No No
6 empty 2.39 64.2 15.7 No No
7 empty 2.59 61.5 13.2 No No
8 empty 2.11 63.8 10.7 No No
9 empty 2.26 57.1 10 No No
10 empty 1.97 57.8 11.2 No No
2BIK_B Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 65.7 51.2 Yes No
2 bound 1.99 72.1 41.5 No No
3 empty 2.23 62.7 17.4 No No
4 empty 2.29 70.2 13 No No
5 empty 2.33 68.9 18.6 No No
6 empty 2.41 60.7 10.8 No No
7 empty 1.82 55 11.1 No No
8 empty 2.27 61.8 10.3 No No
9 empty 1.11 96.8 0 Yes No
10 empty 2.59 69.2 7.2 No No
4ALU_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 75.2 38.8 Yes Yes
2 empty 2.36 67.1 33.7 No No
3 empty 2.26 65.3 18.6 No No
4 bound 2.25 68 13.7 No No
5 empty 1.54 71.8 14.3 No No
6 empty 2.41 66.1 14.9 No No
7 empty 2.09 55.6 17.3 No No
8 empty 2.56 62.4 13 No No
9 empty 2.2 62.3 11.9 No No
10 empty 2.56 66.3 12.5 No No
1YHS_A Serine/threonine-protein kinase pim-1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 63.6 53.7 Yes No
2 bound 2.29 73.3 37.6 No No
3 empty 2.56 67.4 23.1 No No
4 empty 2.18 67.1 21.7 No No
5 empty 2.6 60.4 20.7 No No
6 empty 2.44 68.8 15.2 No No
7 empty 2.15 57.1 14.1 No No
8 empty 1.76 64.8 10.8 No No
9 empty 2.31 62.8 10.7 No No
10 empty 2.53 58.1 10.1 No No
5DWR_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 76.6 36.5 Yes Yes
2 empty 2.33 67.6 34.2 No No
3 empty 2.04 66.3 26.3 No No
4 empty 2.37 65.6 14.9 No No
5 empty 1.61 72 12.2 No No
6 empty 2.36 62.1 20.2 No No
7 empty 2.48 58.9 13.4 No No
8 empty 1.84 62.1 17.2 No No
9 empty 2.65 60.8 14.3 No No
10 empty 1.9 65 9.1 No No
3WE8_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 71.5 42.4 Yes Yes
2 empty 2.08 66.6 31.2 No No
3 bound 2.58 68.9 32.4 No No
4 empty 2.1 63.4 25.5 No No
5 empty 2.48 62.4 12.7 No No
6 empty 2.02 64.5 11.2 No No
7 empty 2.32 65 17.4 No No
8 empty 2.08 76.8 12.8 No No
9 empty 1.77 53 12.8 No No
10 empty 2.11 59.9 14.8 No No
3VC4_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 75 40.3 Yes Yes
2 empty 2.37 64.4 33.9 No No
3 empty 2.32 66.6 17.9 No No
4 empty 2.44 56.9 26.9 No No
5 empty 2.42 69.3 20.9 No No
6 empty 2.61 59.2 19.8 No No
7 empty 2.57 62.7 15 No No
8 bound 2.32 66.2 22.1 No No
9 empty 2.57 69.5 13.5 No No
10 empty 1.67 71.4 13.7 No No
5C1Q_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 76.4 36.8 Yes Yes
2 empty 2.26 67.2 28.5 No No
3 empty 2.31 65.1 34.9 No No
4 empty 1.94 72.1 18.2 No No
5 empty 2.24 64.3 18.2 No No
6 empty 2.52 65.8 11.5 No No
7 empty 2.19 72.2 12.7 No No
8 empty 1.45 59.6 16.4 No No
9 empty 2.54 65.7 10.9 No No
10 empty 1.85 60.9 11.2 No No
4XHK_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 77.4 37.8 Yes Yes
2 empty 2.51 64 36.1 No No
3 empty 2.44 65.4 17.3 No No
4 empty 2.09 55.2 17.1 No No
5 empty 2.23 70.1 14.5 No No
6 empty 1.52 72 14.3 No No
7 empty 2.36 65.3 16.1 No No
8 empty 2.45 63.6 10 No No
9 empty 2.35 62.4 11 No No
10 empty 2.04 63.5 9 No No
5N4N_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 72.9 39.7 Yes Yes
2 empty 2.16 66.6 29.1 No No
3 empty 2.41 64.8 34.6 No No
4 empty 1.92 70.3 13.2 No No
5 empty 2.57 64.1 15.4 No No
6 empty 2.56 58.4 15.5 No No
7 empty 2.04 82.1 10.2 No No
8 empty 1.68 63 10.9 No No
9 empty 2.11 57.4 12.1 No No
10 empty 2.2 57.7 15.1 No No
1YXS_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 75 40.8 Yes Yes
2 empty 2.54 65.4 32.7 No No
3 empty 2.17 64.7 29.9 No No
4 empty 2.13 66.2 24.5 No No
5 empty 2.59 66.7 19.3 No No
6 bound 1.99 68.7 16.3 No No
7 empty 2.4 57.9 15.1 No No
8 empty 2.25 61.9 14.7 No No
9 empty 2.04 67.6 12 No No
10 empty 1.11 97.3 0 Yes No
2O65_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 75.1 37.8 Yes Yes
2 empty 2.21 64.2 48 No No
3 empty 2.44 66.8 32.8 No No
4 empty 2.6 67.1 21.7 No No
5 empty 2.19 61.2 14.3 No No
6 bound 2.14 67.7 16.2 No No
7 empty 2.18 56.6 14.6 No No
8 empty 2.16 78 10.5 No No
9 empty 1.2 98 0 Yes No
10 empty 2.44 57.5 11 No No
5O11_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 74.9 31.4 Yes Yes
2 empty 2.42 66.2 32.7 No No
3 bound 2.19 62.4 20.5 No No
4 bound 2.04 67.7 26 No No
5 empty 2.45 61.8 15.8 No No
6 empty 2.16 66.8 16.4 No No
7 empty 1.63 71.6 10.9 No No
8 empty 2.34 62.8 10.8 No No
9 empty 1.56 54.4 15 No No
10 empty 2.15 77.9 9.6 No No
4K1B_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 73.1 40.6 Yes Yes
2 empty 2.5 67 30.3 No No
3 empty 2.3 64.5 26.3 No No
4 empty 2.33 64.9 14.1 No No
5 empty 1.54 72.8 12.8 No No
6 empty 2.36 62.8 11.8 No No
7 empty 2.01 62.7 17.9 No No
8 empty 2.41 64.2 13.2 No No
9 empty 1.88 79.1 11 No No
10 empty 2.16 69.4 9 No No
2BZK_B Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 70.6 36 Yes Yes
2 empty 2.2 65.9 30.4 No No
3 empty 2.45 66.1 32.6 No No
4 empty 2.32 65.9 19.9 No No
5 empty 2.38 59.5 13.8 No No
6 empty 2.01 86.9 10.3 Yes No
7 empty 2.42 65.1 16.1 No No
8 empty 1.89 67.1 12.1 No No
9 empty 2.4 62.8 12.9 No No
10 empty 1.76 59.4 14.6 No No
6MT0_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 72.8 41 Yes Yes
2 bound 2.32 65.2 24.3 No No
3 empty 2.56 68 31.9 No No
4 empty 2.23 65.2 20.7 No No
5 empty 2.51 66.3 15.6 No No
6 empty 2.62 59.1 13.7 No No
7 empty 2.63 62.3 15 No No
8 empty 1.92 58 18.5 No No
9 empty 1.64 55.6 12.7 No No
10 empty 2.62 61.1 11.1 No No
3F2A_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 75.9 38.7 Yes Yes
2 empty 2.42 70.3 33.4 No No
3 empty 2.2 63.9 23.6 No No
4 empty 2.34 62.5 16.8 No No
5 empty 2.19 56 15.6 No No
6 empty 1.68 70.8 12.4 No No
7 empty 2.42 61.2 11.3 No No
8 empty 2.13 67.9 14.3 No No
9 empty 1.96 67 8.1 No No
10 empty 2.36 65.3 14.2 No No
4K0Y_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 74.9 38.4 Yes Yes
2 empty 2.53 63.5 33.9 No No
3 empty 2.35 64.5 27.8 No No
4 empty 2.26 64.6 15.1 No No
5 empty 2.08 63.9 23.4 No No
6 empty 2.33 65.2 14 No No
7 empty 1.61 72.4 12.1 No No
8 empty 2.24 62 12.5 No No
9 empty 2.42 62.7 14.8 No No
10 empty 2.17 60 16.1 No No
3C4E_C Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 76 40.8 Yes Yes
2 empty 2.48 64.1 38.8 No No
3 empty 2.38 68.1 17 No No
4 empty 2.41 69 19.7 No No
5 empty 2.48 65.7 19.1 No No
6 bound 1.94 73 11.8 No No
7 empty 1.56 73 13.2 No No
8 empty 2.57 61.7 13.4 No No
9 empty 1.93 64.2 16.3 No No
10 empty 2.17 57.9 11.4 No No
4RPV_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 74.4 33.8 Yes Yes
2 empty 2.25 67.2 27.3 No No
3 empty 2.51 63.7 35.6 No No
4 empty 2.35 67.2 27.2 No No
5 empty 2.08 63 24.1 No No
6 empty 2.2 66.4 19.4 No No
7 empty 2.4 61.1 12.6 No No
8 empty 2.47 60.6 10.3 No No
9 empty 1.81 56.1 11.1 No No
10 empty 1.25 98.4 0 Yes No
2O63_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 72 34.4 Yes Yes
2 empty 2.27 65.6 28.5 No No
3 bound 2.41 60.5 29 No No
4 empty 1.97 64.3 12.2 No No
5 empty 2.47 54 14.4 No No
6 empty 2.32 64.2 15.1 No No
7 empty 1.95 54.9 16.6 No No
8 bound 2.08 62.7 11.9 No No
9 empty 2.5 68.5 11 No No
10 empty 2.68 59 13.1 No No
3C4E_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 73 42.4 Yes Yes
2 empty 2.54 64.5 34.5 No No
3 empty 2.35 64.4 21.5 No No
4 empty 2.52 65.1 20.4 No No
5 empty 1.51 71.2 12.4 No No
6 bound 2.04 73.9 12.2 No No
7 empty 2.55 60.5 13.3 No No
8 empty 2.09 59.9 15.8 No No
9 empty 2.53 66.2 13.5 No No
10 empty 2.03 57.5 10.7 No No
3A99_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 70.9 33.7 Yes Yes
2 empty 2.17 68 27 No No
3 empty 2.63 65.1 32.2 No No
4 empty 2.28 68.9 19.9 No No
5 empty 2.37 64.3 21.4 No No
6 empty 2.6 59.1 14.5 No No
7 empty 2.47 65.7 11.5 No No
8 empty 1.95 74.3 8.3 No No
9 empty 1.78 50.6 11.1 No No
10 empty 2.51 60 10.4 No No
5N5L_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 76.5 37.4 Yes Yes
2 empty 2.28 66.6 30.8 No No
3 empty 2.48 65.5 30.1 No No
4 empty 2.38 67.4 22.6 No No
5 empty 2.48 57.3 13.3 No No
6 bound 2.27 67.9 12.7 No No
7 empty 1.92 68.4 15.8 No No
8 empty 1.67 62.6 10.5 No No
9 empty 2.48 70.6 10.6 No No
10 empty 2.02 56.5 11.3 No No
3JY0_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 72.2 37.7 Yes Yes
2 empty 2.55 65.4 31.7 No No
3 empty 2.52 65.9 22 No No
4 empty 1.92 58.5 16 No No
5 empty 2.44 61.4 20.7 No No
6 empty 2.08 69.1 18.8 No No
7 empty 1.64 72.5 12 No No
8 empty 2.49 59.9 12.8 No No
9 empty 2.6 70.1 13.8 No No
10 empty 1.99 62.8 9.2 No No
5KGD_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 71 24.1 Yes Yes
2 bound 2.37 74.2 18.6 No No
3 bound 2.35 61.7 32.7 No No
4 empty 2.16 63.4 19.1 No No
5 bound 2.47 66.1 18.3 No No
6 empty 1.59 68.6 12.8 No No
7 empty 2.47 59.1 11.2 No No
8 empty 1.89 65.9 11.6 No No
9 empty 2.4 60.5 11.8 No No
10 bound 1.93 61.7 10.6 No No
5N51_A Serine/threonine-protein kinase pim-1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 71.7 36.7 Yes Yes
2 empty 2.51 67.2 32.9 No No
3 empty 2.25 69.4 30.3 No No
4 empty 2.08 71.5 16.1 No No
5 empty 1.82 59.4 16.5 No No
6 empty 2.49 63.3 13.8 No No
7 empty 2.04 76.6 11 No No
8 empty 1.75 64.8 9.1 No No
9 empty 1.77 68 11.3 No No
10 empty 1.79 50.8 12.3 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed54
Domains assessed as druggable using the strict criteria50
Domains assessed as druggable using the relaxed criteria53

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1XQZ_A (115857) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 1.8Å Yes Yes
1XR1_A (115859) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 1.7Å Yes Yes
1XWS_A (116133) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 1.8Å Yes Yes
1YHS_A (3020910) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.15Å Yes No
1YI3_A (3020916) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.5Å Yes Yes
1YI4_A (3020917) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.4Å Yes Yes
1YWV_A (3030225) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2Å Yes Yes
1YXS_A (3030243) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.2Å Yes Yes
1YXT_A (3030244) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2Å Yes Yes
1YXU_A (3030245) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2Å Yes Yes
1YXV_A (3030246) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2Å Yes Yes
1YXX_A (3030247) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.96Å Yes Yes
2BIK_B (3050184) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.8Å Yes No
2BIL_B (3050186) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.55Å Yes Yes
2BZH_B (3050553) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.9Å Yes Yes
2BZI_B (3050555) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.9Å Yes Yes
2BZJ_A (3050557) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.05Å Yes Yes
2BZK_B (3050559) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.45Å Yes Yes
2C3I_B (3050698) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.9Å Yes Yes
2J2I_B (3120951) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.9Å Yes Yes
2O3P_A (3160065) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.24Å Yes Yes
2O63_A (3160134) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2Å Yes Yes
2O64_A (3160135) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.44Å Yes Yes
2O65_A (3160136) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.85Å Yes Yes
2OBJ_A (139006) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 2.4Å Yes Yes
2OI4_X (3160655) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.2Å No No
2XIX_A (3580565) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.398Å Yes Yes
2XIY_A (3580566) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.2Å Yes Yes
2XIZ_A (3580567) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.2Å Yes Yes
2XJ0_A (3580568) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 3.099Å Yes Yes
2XJ1_A (3580569) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.13Å Yes Yes
2XJ2_A (3580570) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.2Å Yes Yes
3A99_A (3600868) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.6Å Yes Yes
3BGP_A (155250) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 2.8Å Yes Yes
3BGQ_A (155251) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 2Å Yes Yes
3BGZ_A (155254) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 2.4Å Yes Yes
3BWF_A (3320803) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.35Å Yes Yes
3C4E_A (3330274) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.98Å Yes Yes
3CXW_A (3350222) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.1Å Yes Yes
3CY2_A (3350229) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.01Å Yes Yes
3CY3_A (3350231) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.15Å Yes Yes
3DCV_A (157540) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), Protein kinases catalytic subunit 2.7Å Yes No
3F2A_A (3400065) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 1.9Å Yes Yes
3JPV_A (3480900) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.35Å Yes Yes
3JXW_A (3490349) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.8Å Yes Yes
3JY0_A (3490352) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.4Å Yes Yes
3JYA_A (3490357) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.1Å Yes Yes
3MA3_A (3540824) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.3Å Yes Yes
3QF9_A (3680942) Serine/threonine-protein kinase pim-1 Protein kinase-like (PK-like), Protein kinase-like (PK-like), UNMATCHED 2.2Å Yes Yes
3R00_A (4173817) Serine/threonine-protein kinase pim-1 UNMATCHED, UNMATCHED, UNMATCHED 3R00 2.1Å Yes Yes
3R01_A (4175500) Serine/threonine-protein kinase pim-1 UNMATCHED, UNMATCHED, UNMATCHED 3R01 2.6Å Yes Yes
3R02_A (4250678) Serine/threonine-protein kinase pim-1 UNMATCHED, UNMATCHED, UNMATCHED 3R02 1.95Å Yes Yes
3R04_A (4031430) Serine/threonine-protein kinase pim-1 UNMATCHED, UNMATCHED, UNMATCHED 3R04 1.7Å Yes Yes
3T9I_A (4035220) Serine/threonine-protein kinase pim-1 UNMATCHED, UNMATCHED, UNMATCHED 3T9I 2.6Å Yes Yes
Ligand-based Druggability Score: 1.95
Ligand-based Druggability Score Percentile: 97%
Ligand-based Druggability Help: Help




		
Number of proteins in the network : 13346


PIM1 is involved in 42 interactions in the network.


Druggability
Overall Druggability Percentile: 63.21
Druggability for Cancer Therapeutics: 87.19
Druggability for Other Therapeutics: 30.68
Cancer-Associated
Cancer-associated percentile : 97.11
Network Articulation Point
Is PIM1 critical for communication in the network?


Detailed Graph Legend:Help