Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
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Chemistry
Ligand Efficiency Plot
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Gene Expression
Gene Copy Number Variation
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fadL (P10384) - Overview - Molecular Target Synopsis

Protein


fadL, Long-chain fatty acid transport protein
UniProt P10384

Also Known as FADL_ECOLI, fadL, ttr

Involved in translocation of long-chain fatty acids across the outer membrane. It is a receptor for the bacteriophage T2. FadL may form a specific channel. Has been isolated from outer membrane preparation as a homodimer.

3PGS
PHE3GLY MUTANT OF ECFADL
RCSB/PDB
Inspect Structure
See all 3D Structures for fadL

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
446P10384-1

Sub-cellular localization


UniProt: fadL is active in the following subcellular-locations: cell outer membrane.
GO terms: fadL is active in the following subcellular-locations: cell outer membrane, integral component of membrane, intrinsic component of cell outer membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project fadL has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For fadL there are:
14 structures (27 chains) solved
12 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis