Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

EEF1AKMT4 (P0DPD7) - Overview - Molecular Target Synopsis

Protein


EEF1AKMT4, EEF1A lysine methyltransferase 4
Enzyme Classification 2.1.1.-
UniProt P0DPD7

Also Known as EFMT4_HUMAN, EEF1AKMT4

Protein-lysine methyltransferase that efficiently catalyzes three successive methylations on 'Lys-36' in eukaryotic translation elongation factor 1 alpha (EEF1A1 or EEF1A2).

2PXX
HUMAN PUTATIVE METHYLTRANSFERASE MGC2408
RCSB/PDB
Inspect Structure
See all 3D Structures for EEF1AKMT4

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Gene Copy Number Variation


In COSMIC - Cell Lines Project EEF1AKMT4 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are:

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are:

(see details)

3D Structures


For EEF1AKMT4 there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis