Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

gcl (P0AEP7) - Overview - Molecular Target Synopsis

Protein


gcl, Glyoxylate carboligase
Enzyme Classification 4.1.1.47
UniProt P0AEP7

Also Known as GCL_ECOLI, gcl

Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde). Homotetramer.

2PAN
CRYSTAL STRUCTURE OF E. COLI GLYOXYLATE CARBOLIGASE
RCSB/PDB
Inspect Structure
See all 3D Structures for gcl

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Gene Copy Number Variation


In COSMIC - Cell Lines Project gcl has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For gcl there are:
1 structures (6 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis