Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
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Ligand Efficiency Plot
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fabI (P0AEK4) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFH_A 100 0 2.2Å TDB NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1I2Z_A 100 0 2.8Å 654 NAD 2002-02-12
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 5CG2_A 100 0 2.11Å CJ3 NAD 2015-12-09
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QG6_C 100 0 1.9Å TCL NAD 1999-09-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 4JX8_B 100 0 3.2Å AE6 NAD 2014-04-02
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFI_B 100 0 2.08Å NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 5CFZ_B 100 0 1.969Å - 2015-12-09
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1I30_B 100 0 2.3Å 826 NAD 2002-02-12
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1C14_B 100 0 2Å TCL NAD 2000-07-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 3PJE_B 100 0 2.5Å TCL NAD 2011-04-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QG6_D 100 0 1.9Å TCL NAD 1999-09-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1LXC_B 100 0 2.4Å AYM NAD 2002-09-04
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 5CFZ_A 100 0 1.969Å - 2015-12-09
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFG_A 100 0 2.5Å NDT NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_E 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1LXC_A 100 0 2.4Å AYM NAD 2002-09-04
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 5CG1_B 100 0 2.07Å BBN NAD 2015-12-09
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1D8A_A 100 0 2.18Å TCL NAD 1999-10-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_B 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QG6_B 100 0 1.9Å TCL NAD 1999-09-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1D8A_B 100 0 2.18Å TCL NAD 1999-10-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_A 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFG_B 100 0 2.5Å NDT NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1LX6_B 100 0 2.4Å ZAM NAD 2002-09-04
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_F 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 3PJD_B 100 0 2.5Å TCL NAD 2011-04-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_G 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) acpP (P0A6A8) 2FHS_A 100 0 2.7Å - 2006-10-17
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_C 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1I30_A 100 0 2.3Å 826 NAD 2002-02-12
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFI_D 100 0 2.08Å NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_D 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1MFP_B 100 0 2.33Å IDN NAD 2003-05-06
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 4JQC_A 100 0 2.6Å 0WE NAD 2014-03-26
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1I2Z_B 100 0 2.8Å 654 NAD 2002-02-12
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 3PJF_A 100 0 1.9Å TCL NAD 2011-04-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 4JX8_A 100 0 3.2Å AE6 NAD 2014-04-02
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFI_A 100 0 2.08Å NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 3PJE_A 100 0 2.5Å TCL NAD 2011-04-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1MFP_A 100 0 2.33Å IDN NAD 2003-05-06
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFI_C 100 0 2.08Å NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QSG_H 100 0 1.75Å TCL NAD GLC 1999-07-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) acpP (P0A6A8) 2FHS_B 100 0 2.7Å - 2006-10-17
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1QG6_A 100 0 1.9Å TCL NAD 1999-09-21
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 4JQC_B 100 0 2.6Å 0WE NAD 2014-03-26
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 3PJD_A 100 0 2.5Å TCL NAD 2011-04-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1LX6_A 100 0 2.4Å ZAM NAD 2002-09-04
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1DFH_B 100 0 2.2Å TDB NAD 1998-01-28
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 1C14_A 100 0 2Å TCL NAD 2000-07-20
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 5CG1_A 100 0 2.07Å BBN NAD 2015-12-09
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 5CG2_B 100 0 2.11Å CJ3 NAD 2015-12-09
Enoyl-(Acyl carrier protein) reductase (100%) (view alignment) fabI (P0AEK4) - 3PJF_B 100 0 1.9Å TCL NAD 2011-04-20