Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

corC (P0AE78) - Overview - Molecular Target Synopsis

Protein


corC, Magnesium and cobalt efflux protein CorC
UniProt P0AE78

Also Known as CORC_ECOLI, corC, ybeX

Plays a role in the transport of magnesium and cobalt ions.

5YZ2
THE CYSTATHIONINE-BETA-SYNTHASE (CBS) DOMAIN OF MAGNESIUM AND COBALT EFFLUX PROTEIN CORC IN COMPLEX WITH BOTH C2'- AND C3'-ENDO AMP
RCSB/PDB
Inspect Structure
See all 3D Structures for corC

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


GO terms: corC is active in the following subcellular-locations: plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project corC has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For corC there are:
2 structures (3 chains) solved
2 are solved in complex with at least one small molecule ligand
2 are solved with an approved drug

corC is solved in complex with the approved drug(s):

AMP/ADENOSINE PHOSPHATE (4HG0_A, 5YZ2_A, 5YZ2_B).

(see details)
Molecular Target 3D Synopsis