Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpsB (P0A7V0) - Overview - Molecular Target Synopsis

Protein


rpsB, 30S ribosomal protein S2
UniProt P0A7V0

Also Known as RS2_ECOLI, rpsB

Required for ribosomal protein S1 to bind to the 30S subunit. Part of the 30S ribosomal subunit, contacts S1 (PubMed:12068815). Some nascent polypeptide chains are able to cross-link to this protein in situ (PubMed:9716382).

5NO3
RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE WITHOUT US3)
RCSB/PDB
Inspect Structure
See all 3D Structures for rpsB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


GO terms: rpsB is active in the following subcellular-locations: cytosolic small ribosomal subunit.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpsB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpsB there are:
12 structures (23 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


rpsB has been screened with compounds ( bioactivities). (see details)