Molecular Target Synopsis
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rpsT (P0A7U7) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 03/09/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 03/09/2019)


Chains assessed10
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria8


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
2YKR_T 30S ribosomal protein S20 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.35 54.2 22.1 No No
2 empty 2.46 62.1 24 No No
3 empty 2.3 51 12.1 No No
4 empty 2.43 48 14.2 No No
5 empty 2.13 70.5 9.1 No No
6 empty 2.06 65 10.2 No No
7 empty 1.97 58.6 9.3 No No
8 empty 2.34 60.4 8.3 No No
9 empty 3.03 47.1 8.1 No No
10 empty 1.83 50.5 5.8 No No
5NO3_T 30S ribosomal protein S20 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.67 59.4 16.4 No No
2 empty 2.56 74.9 13.2 No No
3 empty 2.12 66 12.3 No No
4 empty 1.88 64.8 7.4 No No
5 empty 2.58 53.1 12.9 No No
6 empty 2.4 82.5 12.6 No No
7 empty 2.62 55.5 7 No No
8 empty 2.23 57.4 6.4 No No
9 empty 1.93 41.6 8.2 No No
10 empty 2.28 71 5.1 No No
5NO4_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.62 59.6 14.9 No No
2 empty 2.12 63.4 13.1 No No
3 empty 2.5 76.3 13.4 No No
4 empty 2.56 50.5 15.2 No No
5 empty 1.82 64.6 9.6 No No
6 empty 2.12 50.4 14.1 No No
7 empty 2.46 66.7 8.6 No No
8 empty 2.69 71.1 7.3 No No
9 empty 2.2 98 0 Yes No
10 empty 2.4 62 6.5 No No
5ME0_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.53 57.9 18.3 No No
2 empty 2.31 63 14.7 No No
3 empty 1.87 71.7 7.5 No No
4 empty 2.3 74.3 11.5 No No
5 empty 2.01 54.8 11 No No
6 empty 2.26 68.3 6.9 No No
7 empty 2.97 57.6 9.1 No No
8 empty 2.89 48.3 8.3 No No
9 empty 2.13 97.8 0 Yes No
10 empty 2.27 69.2 4.7 No No
5UZ4_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 65.6 18.8 No No
2 empty 2.39 54.5 18.2 No No
3 empty 2.88 54.7 9.9 No No
4 empty 2.77 55.6 10.8 No No
5 empty 2.77 50 10.4 No No
6 empty 1.72 74.8 6.4 No No
7 empty 1.71 63.9 7.1 No No
8 empty 1.84 70.2 6.7 No No
9 empty 2.32 59.6 6.9 No No
10 empty .93 98.6 0 Yes No
5MY1_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.44 54.7 21.9 No No
2 empty 1.79 66.4 7.7 No No
3 empty 2.01 66.9 6.2 No No
4 empty 2 62 9 No No
5 empty 2.17 59.6 7.6 No No
6 empty 1.76 61.9 10.6 No No
7 empty 2.24 97.1 0 Yes No
8 empty 2.27 50 9.4 No No
9 empty 2.4 65.3 5.7 No No
10 empty 2.64 55.1 5.7 No No
5NO2_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.65 59 16.5 No No
2 empty 2.6 75.1 13.7 No No
3 empty 2.1 64.1 12.7 No No
4 empty 2.6 54.2 15.3 No No
5 empty 1.99 63.2 11 No No
6 empty 1.93 95.9 0 Yes No
7 empty 2.48 56.8 8 No No
8 empty 2.55 67.8 6.5 No No
9 empty 2.17 58.9 8.7 No No
10 empty 1.92 46.7 8.2 No No
4A2I_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.32 53.4 23.6 No No
2 empty 2 64.9 13.5 No No
3 empty 2.02 64.1 7.3 No No
4 empty 2.19 66.1 9.5 No No
5 empty 2.18 94.9 0 Yes No
6 empty 2.54 58.2 9.8 No No
7 empty 2.47 75.6 0 No No
8 empty 2.81 61.1 7.7 No No
9 empty 2.76 51.8 6.2 No No
10 empty 2.28 65.9 5.4 No No
5ME1_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.71 58.2 18.9 No No
2 empty 2.34 65.8 14.3 No No
3 empty 2.21 72.9 13.8 No No
4 empty 1.92 67.8 8.5 No No
5 empty 1.91 55.4 12.1 No No
6 empty 2.8 58.3 13.1 No No
7 empty 2.22 78.1 0 No No
8 empty 2.21 95.6 0 Yes No
9 empty 2.26 63.9 8.1 No No
10 empty 2.19 47.1 6.7 No No
4ADV_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 54.9 15 No No
2 empty 2.01 66.6 12.5 No No
3 empty 2.1 61.2 9.7 No No
4 empty 2.35 62.3 8.4 No No
5 empty 2.21 97.2 0 Yes No
6 empty 2.75 63.4 6.4 No No
7 empty 3.07 59.8 6.3 No No
8 empty 1.47 58.3 8 No No
9 empty 2.79 61.3 7.1 No No
10 empty 2.43 66.1 6.8 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed47
Domains assessed as druggable using the strict criteria0
Domains assessed as druggable using the relaxed criteria10

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1VS5_T (144454) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.46Å No No
1VS7_T (144495) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.46Å No No
2AVY_T (144861) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.46Å Yes No
2AW7_T (144904) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.46Å No No
2GY9_T (145239) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 15Å No No
2GYB_T (145261) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 .5Å Yes No
2I2P_T (145439) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.2Å Yes No
2I2U_T (145481) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.2Å No No
2QAL_T (150232) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.21Å No No
2QAN_T (150286) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.21Å No No
2QB9_T (150346) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.54Å No No
2QBB_T (150399) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.54Å No No
2QBD_T (150452) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.3Å No No
2QBF_T (150506) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.3Å No No
2QBH_T (150560) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 4Å No No
2QBJ_T (150614) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 4Å No No
2QOU_T (151003) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.93Å No No
2QOW_T (151056) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.93Å No No
2QOY_T (151109) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.5Å No No
2QP0_T (151162) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.5Å No No
2WWL_T (3260094) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 5.8Å No No
2Z4K_T (154070) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 4.45Å No No
2Z4M_T (154124) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 4.45Å No No
3DF1_T (157622) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.5Å No No
3DF3_T (157676) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.5Å No No
3FIH_T (3410181) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 6.7Å No No
3I1M_T (4191316) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3I1M 3.19Å No No
3I1O_T (4118400) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3I1O 3.19Å Yes No
3I1Q_T (4202800) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3I1Q 3.8Å Yes No
3I1S_T (4093895) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3I1S 3.8Å No No
3I1Z_T (4002592) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3I1Z 3.7Å No No
3I21_T (4168538) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3I21 3.7Å No No
3IZV_X (3620491) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 13.2Å No No
3IZW_X (3620519) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 8.25Å Yes No
3KC4_T (3500325) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 9.6Å Yes No
3OAQ_T (3650103) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.25Å Yes No
3OAR_T (3650125) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.25Å No No
3OFA_T (4107309) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OFA 3.19Å No No
3OFB_T (4119980) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OFB 3.19Å No No
3OFO_T (4043266) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OFO 3.1Å No No
3OFP_T (4241444) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OFP 3.1Å No No
3OFX_T (4118818) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OFX 3.289Å No No
3OFY_T (4006348) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OFY 3.289Å Yes No
3OR9_T (4224951) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3OR9 3Å Yes No
3ORA_T (4201798) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3ORA 3Å No No
3R8N_T (4128227) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3R8N 3Å No No
3R8O_T (4109742) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 3R8O 3Å No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score