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kcsA (P0A334) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/07/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 23/07/2019)


Chains assessed89
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria36


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
3HPL_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.23 54.1 14 No No
2 empty 1.09 64.4 16.1 No No
3 empty .91 66.6 16.9 No No
4 empty 1.87 70.2 8.8 No No
5 empty .8 70 10.9 No No
6 empty .51 63.5 9.5 No No
7 empty 2.2 46.7 8.1 No No
8 empty 2.69 73.9 9.7 No No
9 empty 1.93 61.8 7.1 No No
10 empty 2.49 62.7 6.6 No No
4UUJ_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 59.3 20.1 No No
2 bound .89 61.2 16.1 No No
3 empty .96 59.9 11 No No
4 empty 1.99 54.6 13.4 No No
5 empty 1.98 69 12.2 No No
6 empty 1.33 58 12.6 No No
7 empty 1.24 65.1 10.2 No No
8 empty .98 63.5 8.7 No No
9 empty .36 70.7 9.4 No No
10 empty 2.02 50.8 8.3 No No
3OGC_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 56.6 16.9 No No
2 empty 1.87 71.4 10.1 No No
3 empty 1.8 67.9 12.8 No No
4 empty 1.16 64.9 10.2 No No
5 empty 2.32 58.2 14 No No
6 empty .44 65.5 12.5 No No
7 empty 1.99 52.5 10.6 No No
8 empty .81 68.9 8 No No
9 empty .83 72.2 7.8 No No
10 empty 2.59 75.3 8.6 No No
3PJS_M pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .97 77.1 13.3 Yes No
2 empty 1.11 73.1 14.6 Yes No
3 empty 2.11 69.1 10.6 No No
4 empty 1.66 60 18.6 No No
5 empty 2.38 53.5 14.1 No No
6 empty 1.5 69.9 11.3 No No
7 empty 2.49 53.7 13.7 No No
8 empty 2.12 49.5 9 No No
9 empty .42 68.9 9.8 No No
10 empty 2.55 68.3 8 No No
2H8P_D pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.69 53 15.3 No No
2 empty 2.37 59.3 11.8 No No
3 empty 1.34 60 5.5 No No
4 empty .22 65.3 5.6 No No
5 empty 2.16 50 7.7 No No
6 empty .51 55.6 5.5 No No
7 empty 3.07 57.7 6.4 No No
8 empty .51 47.8 5.4 No No
2BOB_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 73.2 15 Yes No
2 empty 2.12 54.8 12.3 No No
3 empty 1.06 67.5 11.5 No No
4 empty 2.29 58.9 11.2 No No
5 empty .95 75.8 9.2 No No
6 empty 1.1 66.5 8.6 No No
7 empty .96 71.9 8.3 No No
8 empty 1.72 57.6 11.2 No No
9 bound 1.62 59.2 10.5 No No
10 empty 1.82 61 7.4 No No
3STL_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 69 10.6 No No
2 empty 1.76 53.6 10 No No
3 empty 1.05 60.7 12.8 No No
4 empty .85 68.2 13.4 No No
5 empty 1.47 58.2 10.3 No No
6 empty .89 75.9 7.5 No No
7 empty 1.93 53.3 9 No No
8 empty 1.98 50.6 8.3 No No
9 empty .7 67.3 7.1 No No
10 empty .38 79.8 6.5 No No
5J9P_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 72.3 10.3 Yes No
2 empty 1.15 68.8 12.4 No No
3 empty 2.25 50.2 11.1 No No
4 empty 1.45 54.2 8.9 No No
5 empty 1.86 57.9 8.4 No No
6 empty 1.98 52.7 9.2 No No
7 empty .97 67.6 8.6 No No
8 empty .93 68.1 6.8 No No
9 empty 2.76 70.7 8.8 No No
10 empty .34 72.8 7.2 No No
2HVK_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.21 55.4 15.4 No No
2 empty 2.16 71.5 10.7 No No
3 empty 2.03 52.6 11.5 No No
4 empty 1.24 66.3 10.2 No No
5 empty .62 59.6 8.6 No No
6 empty .9 70.8 9.8 No No
7 bound 1.49 57.5 8 No No
8 empty 1.1 66 8.1 No No
9 empty 1.92 55.8 8 No No
10 empty 2.11 53.9 8.2 No No
2BOC_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.32 58.2 15.4 No No
2 empty 2.12 70.1 12.2 No No
3 empty 1.22 66.3 10.2 No No
4 empty .84 77.5 11.4 No No
5 empty 1.28 52.7 11.1 No No
6 empty .79 73.8 7 No No
7 empty 1.38 53.2 10 No No
8 empty .55 66.1 9.4 No No
9 empty 2.65 68.9 9.8 No No
10 empty 1.99 47.7 7.4 No No
3FB5_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 68 11.9 No No
2 empty 1.19 72.5 10.9 Yes No
3 empty .56 62.4 8.4 No No
4 empty 1.68 68.2 6.7 No No
5 empty 1.32 52.6 10.4 No No
6 empty 1.94 60.7 9 No No
7 empty .35 69.9 8.3 No No
8 empty 2.87 75.3 9.2 No No
9 empty 2.71 61.1 6.3 No No
10 empty .62 72.7 6.5 No No
1R3J_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 54.9 13.6 No No
2 empty 2.12 70.9 13.3 No No
3 empty 1.89 50.4 10.9 No No
4 empty 1.21 69.6 10.3 No No
5 empty .61 62.8 9.8 No No
6 empty .83 76.1 10 No No
7 empty 1.83 61.6 8.2 No No
8 empty 1.52 53.5 8.5 No No
9 empty 1.13 57.8 9.4 No No
10 empty .35 72.2 7.5 No No
5EBL_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 67.2 13 No No
2 empty 1.96 51.7 11.1 No No
3 empty 1.08 64.4 13.4 No No
4 empty 2.05 52.2 10.6 No No
5 empty 1.8 56.8 10.4 No No
6 empty .7 67.3 6.4 No No
7 empty 1.96 61.1 8.2 No No
8 empty 1.12 66.8 9.8 No No
9 empty .87 69.6 6.7 No No
10 empty 1.45 57 11.3 No No
3PJS_L pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 52.8 16.7 No No
2 empty 1.91 68.7 11.5 No No
3 empty .37 65.9 12.7 No No
4 empty .97 69.8 7.9 No No
5 empty 2.46 55 13.7 No No
6 empty 2.39 67.1 10.7 No No
7 empty .77 73.8 10.2 No No
8 empty 1.15 65.2 8.3 No No
9 empty 1.2 60.8 10 No No
10 empty 2.41 47.1 10.1 No No
3FB7_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 72.3 13.3 Yes No
2 empty 1.6 51.4 14.2 No No
3 empty 1.13 59.4 13.6 No No
4 empty 1.08 59.4 9.8 No No
5 empty .86 61.4 11.6 No No
6 empty 2.65 74.9 8.2 No No
7 empty 1.97 54.5 8.5 No No
8 empty .3 72.7 7.7 No No
9 empty 2.51 67.4 7.2 No No
10 empty .26 67.6 6.9 No No
5VKE_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.39 59.5 16 No No
2 empty 1.98 73.5 9.8 No No
3 bound 1.19 66 10.4 No No
4 empty 2.38 56.2 9 No No
5 empty .65 57.9 13.8 No No
6 empty 1.5 62.6 10.2 No No
7 empty .34 73.8 8 No No
8 empty 1.97 55 7.8 No No
9 empty 2.82 60.4 8.2 No No
10 empty 2.83 72.6 6.4 No No
2A9H_A pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 69.8 18.8 No No
2 empty 1.32 76.5 9.8 Yes No
3 empty 1.94 51.8 9.9 No No
4 empty 1.88 64.2 8.6 No No
5 empty 1.12 70.6 6.6 No No
6 empty 2.61 57.1 7.4 No No
7 empty .63 72.9 6 No No
8 empty .43 78.9 0 No No
9 empty 1.75 56.6 7.1 No No
10 empty .3 44.9 7.3 No No
1ZWI_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 75.8 16.4 Yes No
2 empty 1.96 54.8 10.6 No No
3 empty 1.2 65.8 10.3 No No
4 empty 1.84 46.4 9 No No
5 empty 1.08 64 9.7 No No
6 empty .81 67.9 10.4 No No
7 empty .26 69.5 7.5 No No
8 empty 1.54 56.4 8.5 No No
9 empty 1.93 54.8 8 No No
10 empty .91 64.3 8.5 No No
1R3I_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 71.5 10.3 Yes No
2 empty 2.01 49.8 12.4 No No
3 empty 1.65 57.8 12.2 No No
4 empty 1.23 65.3 10 No No
5 empty .9 70.3 10.1 No No
6 empty .63 62 7.2 No No
7 empty .85 74.4 8.3 No No
8 empty 1.49 57.9 10.4 No No
9 empty 2.11 57.3 6.3 No No
10 empty 1.24 66.8 9.5 No No
2NLJ_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 71.6 13.4 Yes No
2 empty 1.04 68 14.5 No No
3 empty 1.69 54.8 11.3 No No
4 empty 1.79 55.8 12.1 No No
5 empty .99 65.6 7.3 No No
6 empty .95 68.3 8.8 No No
7 empty 1.85 46.7 10.1 No No
8 empty 1.65 55.7 8.6 No No
9 empty 1.11 63.5 10.6 No No
10 empty 2.07 58.5 7.5 No No
3EFF_N pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.08 66.1 30.7 Yes No
2 empty 2.03 72.1 9.2 No No
3 empty 1.45 55.8 16.4 No No
4 empty 2.43 60 11.9 No No
5 empty .64 75.9 8 No No
6 empty 3.06 60.3 10.6 No No
7 empty 1.66 63 7.9 No No
8 empty 1.35 55.3 8 No No
9 empty 2.01 43.3 9.8 No No
10 empty 1.61 51.9 7.6 No No
2ATK_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 58.5 14.6 No No
2 empty 1.92 76.1 14.2 No No
3 empty 2.13 65.1 12.2 No No
4 empty 1.21 56.1 12.4 No No
5 bound 1.24 63.3 10.1 No No
6 empty .38 69.3 7 No No
7 empty .82 72.6 9.7 No No
8 empty 2.66 62 10.6 No No
9 empty 1.45 53.1 10.9 No No
10 empty 1.93 48.7 9.7 No No
1K4C_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 71.7 12.6 Yes No
2 empty 1.67 54.3 11.9 No No
3 empty 1.79 52.7 12.8 No No
4 empty 1.27 69.1 10.9 No No
5 empty .86 78.3 6.2 No No
6 empty .63 60 9 No No
7 empty 1.47 54.2 8.5 No No
8 empty 1.13 63.2 8 No No
9 empty 1.99 47 8.3 No No
10 empty .94 68.5 7.7 No No
3F7Y_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 67.4 15.2 No No
2 empty .55 75.7 7.9 Yes No
3 empty 1.08 67.5 10.6 No No
4 empty .52 61.5 14.6 No No
5 empty 1.89 60.8 8 No No
6 empty 2.77 74.7 10.2 No No
7 empty 1.22 72.4 11.4 No No
8 empty .3 79.1 5.9 No No
9 empty 2.57 64.2 6.7 No No
10 empty 1.33 60.5 7.4 No No
3F7V_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.51 60.3 14.6 No No
2 empty 1.9 71.6 11.5 No No
3 empty 1.96 59.2 13.1 No No
4 empty .75 67.7 8.9 No No
5 empty 1.44 69.5 9.4 No No
6 empty .6 69 6.3 No No
7 empty 2.56 67.8 6.1 No No
8 empty .14 59.8 6.1 No No
9 empty .35 61.5 7.2 No No
10 empty 2.89 67.3 7.2 No No
1BL8_A pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 75.4 16 Yes No
2 empty 2.03 48.1 13.5 No No
3 empty 1.66 58.4 11.9 No No
4 empty 1.04 67.6 8.7 No No
5 empty 1.63 61.8 7.5 No No
6 empty 1.63 72.9 6.1 No No
7 empty .99 69.2 6.8 No No
8 empty 2.61 66.2 8.8 No No
9 empty .81 73.8 7 No No
10 empty 1.1 63.3 7.4 No No
3STZ_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.24 72.1 10.8 Yes No
2 empty 1.95 54.1 10.3 No No
3 empty 1.79 53.6 11.4 No No
4 empty 1.12 66.2 13.1 No No
5 empty .86 64.4 13 No No
6 empty .9 76.5 9.1 No No
7 empty .62 64.5 7.9 No No
8 empty 1.42 54.2 11.2 No No
9 empty 2.03 51.8 8.5 No No
10 empty 1.88 53.9 8.3 No No
1BL8_D pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 73.1 16.6 Yes No
2 empty 2.01 49.3 14.4 No No
3 empty 1.7 64.8 8.5 No No
4 empty 1.11 68.7 8.9 No No
5 empty 1.86 58.1 9.5 No No
6 empty 1.02 72 11.2 No No
7 empty .68 70.5 7.6 No No
8 empty 1.67 72.3 5.6 No No
9 empty .81 71.1 7.6 No No
10 empty 2.64 64.8 9 No No
1JVM_D pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.99 68 11.8 No No
2 empty .86 75.6 7.4 Yes No
3 empty 1.97 53.2 9.8 No No
4 empty .79 62.1 11.2 No No
5 empty 1.43 62.4 10.1 No No
6 empty 2.15 54.7 10.3 No No
7 empty 1.52 67.1 6.9 No No
8 empty 2.31 61.4 7.3 No No
9 empty .19 74 6.2 No No
10 empty .44 78.4 6.6 No No
2DWD_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.48 62.2 17.1 No No
2 empty 1.97 52.7 10.9 No No
3 empty 2.12 70.8 12.9 No No
4 empty 1.76 53.3 12.2 No No
5 empty 1.01 64.3 8.9 No No
6 empty .92 79.2 7.1 No No
7 empty .95 71.4 9.2 No No
8 bound 1.49 54.7 8.6 No No
9 empty 1.05 61.3 10.9 No No
10 empty 2 49.7 6.9 No No
3PJS_K pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.36 56.3 15.2 No No
2 empty 2.09 69 16.3 No No
3 empty 2.54 56.9 11.5 No No
4 empty .99 72.3 9.4 No No
5 empty .97 71 7.2 No No
6 empty 2.21 55.9 7.9 No No
7 empty .29 69.3 7.5 No No
8 empty 2.6 69.3 9.9 No No
9 empty 1.17 58.2 9.4 No No
10 empty 1.59 67.4 10.6 No No
3FB8_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 67.6 12.7 No No
2 empty .56 63.5 10.9 No No
3 empty 1.16 67.4 10.4 No No
4 empty 2.22 52.7 9.8 No No
5 empty 2.55 73.6 8.9 No No
6 empty 1.79 59.8 8.7 No No
7 empty 1.4 60.5 8 No No
8 empty 1.15 76.2 6.9 No No
9 empty .12 73.6 7.3 No No
10 empty 1.58 59.4 7.3 No No
1S5H_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 56.6 11.7 No No
2 empty 2.09 71.9 12.1 No No
3 empty 1.92 53.5 10.2 No No
4 empty 1.09 67.4 10.3 No No
5 empty .89 71.7 9.1 No No
6 empty .84 78.1 7.1 No No
7 empty 1.05 62.8 6.5 No No
8 empty 1.76 56 9.3 No No
9 empty 1.03 63.9 8.4 No No
10 empty 1.32 57 8 No No
3IFX_D pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 74.3 15.3 Yes No
2 empty .9 71.3 10.8 Yes No
3 empty .69 67.1 8.7 No No
4 empty 2.08 56.3 10 No No
5 empty 1.44 70 7.8 No No
6 empty 1.35 56.6 8.6 No No
7 empty 1.05 72.5 6.5 No No
8 empty 1.61 63.9 7.8 No No
9 empty .25 72.1 7 No No
10 empty .64 73.1 6.4 No No
2H8P_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 59.3 14.6 No No
2 empty 2.14 50 11.6 No No
3 empty 1.07 69.3 9.1 No No
4 empty .66 69.7 5.6 No No
5 empty 2.74 67 5.6 No No
6 empty 1.51 48.5 6.5 No No
7 empty 1.38 60.6 7.8 No No
8 empty 1.39 52.8 5.8 No No
9 empty .59 48.4 5.4 No No
10 empty .5 57.8 6.3 No No
1J95_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 72.6 10.3 Yes No
2 empty 1.8 56 14.2 No No
3 empty .81 74.2 9.3 No No
4 empty .8 69.3 8.5 No No
5 empty 1.43 67.3 7.9 No No
6 empty 1.01 65.6 9.7 No No
7 empty .83 74.5 5.1 No No
8 empty 1.91 64.2 5.6 No No
9 empty 2.57 69.3 8.3 No No
10 empty 1.76 59.3 6.2 No No
2QTO_A pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 69.5 14.2 No No
2 empty 2.35 51.6 11.9 No No
3 empty .92 71 9.9 No No
4 empty 1.65 56.4 11.8 No No
5 empty 1.31 65.4 8.3 No No
6 empty .83 65.9 9.1 No No
7 empty .77 75.5 6.7 No No
8 empty .48 71 6.4 No No
9 empty 1.49 67.2 5.9 No No
10 empty 2.08 60.6 6.6 No No
1K4D_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 73.1 13.5 Yes No
2 empty 2.14 57.5 12.2 No No
3 empty 2.12 54.1 14.2 No No
4 bound 1.14 65.5 14.2 No No
5 empty .84 67.1 10.5 No No
6 empty .61 63.4 7.5 No No
7 empty 1.66 57.6 8.7 No No
8 empty 2.7 68.8 9.7 No No
9 empty 1.24 63.5 9.7 No No
10 empty 1.97 63 8.6 No No
1JVM_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 73.1 9 Yes No
2 empty 1.82 60.9 17.8 No No
3 empty .84 74.3 10.2 No No
4 empty .81 68.8 10.3 No No
5 empty 1.51 59.7 7.6 No No
6 empty 2.08 52 10.9 No No
7 empty .27 61.4 7 No No
8 empty 2.26 65.3 6.7 No No
9 empty .7 70.5 6.2 No No
10 empty .43 76.6 5.8 No No
3IFX_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 74 18.3 Yes No
2 empty 2.28 59.8 9.1 No No
3 empty .72 72.4 6.5 No No
4 empty 1 69.2 8.4 No No
5 empty 1.98 71.6 9.1 No No
6 empty 1.34 53.8 9 No No
7 empty .74 66.7 7.5 No No
8 empty 1.77 68.5 5.3 No No
9 empty 2.36 60 5.6 No No
10 empty .38 74.4 5.5 No No
5EBW_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 70.7 11.3 No No
2 empty 1.96 50.8 11.1 No No
3 empty 1.07 62.6 13.7 No No
4 empty 1.76 46.8 10.2 No No
5 empty 1.96 57.1 9.8 No No
6 empty 1.5 61.4 8 No No
7 empty .72 66.4 9 No No
8 empty 1.9 51.7 7.9 No No
9 empty .34 73.9 9.3 No No
10 empty .89 69.7 10.8 No No
2A9H_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 63.3 11.1 No No
2 empty 1.35 61.6 10.1 No No
3 empty 1.99 50 8.4 No No
4 empty 1.84 67 7.8 No No
5 empty 2.34 60.4 8.7 No No
6 empty .81 72.3 7.1 No No
7 empty 1.55 54.1 6.5 No No
8 empty .41 76.1 0 No No
9 empty 2.36 100 0 Yes No
10 empty .59 46.2 7.3 No No
2A9H_B pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 66.4 11.3 No No
2 empty 1.36 68.6 8.8 No No
3 empty 1.99 56.7 8.4 No No
4 empty 1.29 67.8 8 No No
5 empty .74 71.9 5.9 No No
6 empty 1.9 61.7 7.7 No No
7 empty .59 53.6 7.5 No No
8 empty 2.24 64.2 6.3 No No
9 empty 2.42 100 0 Yes No
10 empty .63 76.2 0 No No
3GB7_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 72.6 12.3 Yes No
2 empty 2.2 56.5 10.4 No No
3 empty 1.16 67 9.6 No No
4 empty 1.84 50.5 9.6 No No
5 empty .56 62.9 12 No No
6 empty .35 69.2 8.8 No No
7 empty .77 72.5 6.5 No No
8 empty 1.14 62.6 10.5 No No
9 empty 1.55 60.6 10.1 No No
10 empty .88 70.1 8.4 No No
2HJF_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.32 59.4 14.1 No No
2 empty 1.95 55 9.5 No No
3 empty 1.85 73.8 9.8 No No
4 empty 1.14 69.9 10.5 No No
5 empty 1.06 63.7 10.1 No No
6 empty .9 77 6.8 No No
7 empty 2.56 68.3 10.2 No No
8 empty .89 65.9 10.5 No No
9 empty 1.92 53 6.5 No No
10 bound 1.46 53.6 9.1 No No
2P7T_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 56.3 12 No No
2 empty 2.28 54.8 14.6 No No
3 empty 2.23 76.3 15.4 No No
4 empty 1.06 67.9 13.3 No No
5 empty .55 63.4 9.6 No No
6 empty .88 79.1 6.4 No No
7 empty 1.48 55 10.3 No No
8 empty 2.11 49.2 8.2 No No
9 empty .95 71.3 6.6 No No
10 empty 1.22 67.1 8.5 No No
3OR6_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 73 12.1 Yes No
2 empty 1.76 53.4 9.2 No No
3 empty 1.12 63.3 13.3 No No
4 empty .57 62.8 7.8 No No
5 empty .82 67.4 14.6 No No
6 empty 2.01 50.6 8.3 No No
7 empty .89 77 6.3 No No
8 empty 1.47 58.9 7.9 No No
9 empty 1.96 57.9 9.3 No No
10 empty 2.86 72.3 9.7 No No
5EC2_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.38 62.7 17.2 No No
2 empty 2.15 58.2 10.6 No No
3 empty 2.25 72.3 9.6 No No
4 empty 1.41 53.3 9.4 No No
5 empty .76 63.5 9.2 No No
6 empty .32 72 8.1 No No
7 empty 1.56 57.6 7.7 No No
8 empty 1.12 71.6 6.5 No No
9 empty 2.45 69.1 6.8 No No
10 empty 1.04 75.8 6.7 No No
3PJS_N pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty .76 70.7 19.6 No No
2 empty 2.04 73.2 12.4 No No
3 empty 2.19 52.6 16 No No
4 empty 1.61 70.6 10.3 No No
5 empty 1.01 72.3 15.6 No No
6 empty 1.25 72.5 8.7 No No
7 empty 1.11 53.7 10.7 No No
8 empty 2.63 45.7 10.2 No No
9 empty 2.15 64.3 10.4 No No
10 empty 1.08 57.2 9 No No
3IGA_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 56.5 11.4 No No
2 empty 1.65 70.7 10.6 No No
3 empty 2.09 54 12.4 No No
4 empty 1.18 68.9 10.8 No No
5 empty .86 70.8 10.1 No No
6 empty .97 77.7 8.8 No No
7 empty 1.43 53.2 12.5 No No
8 empty 1.01 63.8 9.1 No No
9 empty .92 67.1 8.5 No No
10 empty 2.78 68.8 8.5 No No
2JK5_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 57.6 18.7 No No
2 empty 2.13 71.3 11.8 No No
3 empty 2.04 53.4 13.2 No No
4 bound 1.16 62.4 10.1 No No
5 empty .62 61.6 8.5 No No
6 empty 2.06 49 7.9 No No
7 empty 1.15 68.9 9.9 No No
8 bound .36 76.7 6 No No
9 bound 1.63 56.4 10.3 No No
10 empty 2.03 65.2 6.5 No No
1JVM_A pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 68.9 13.7 No No
2 empty .83 71.6 8.4 Yes No
3 empty 1.37 64.3 9.4 No No
4 empty .78 64.9 10.1 No No
5 bound 1.57 59.3 10.1 No No
6 empty 1.97 50.3 8.6 No No
7 empty 2.19 54.3 8.3 No No
8 empty 1.65 64.2 6.5 No No
9 empty .75 66.2 5.1 No No
10 empty .17 74.5 6.9 No No
5EBM_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.61 61.4 17 No No
2 empty 1.78 73.5 11.5 No No
3 bound .98 70 15.7 No No
4 empty 1.89 52.5 11.5 No No
5 empty .75 64.2 8.7 No No
6 empty .72 65.2 8 No No
7 empty 1.91 65.4 6.7 No No
8 empty 1.59 59.6 10.9 No No
9 empty 2.82 74.8 7.8 No No
10 empty 1.15 75.2 6.1 No No
2IH1_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.2 64.9 15.4 No No
2 empty 1.74 57.7 12.8 No No
3 empty 2.13 70 11.4 No No
4 empty 1.12 69.1 13.1 No No
5 empty 1.05 61.4 11.7 No No
6 empty .81 71.8 8.1 No No
7 empty 2.48 50 7.8 No No
8 empty 2.04 52.2 6.6 No No
9 empty 2.74 72.7 9.3 No No
10 empty 1.33 65 9 No No
2DWE_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 57.3 12.4 No No
2 empty 2.13 69 13.1 No No
3 bound 1.19 69 10.2 No No
4 empty .86 80.5 6.1 No No
5 empty 3.21 60.4 13 No No
6 empty 1.03 69 7.9 No No
7 bound 1.51 56 9.3 No No
8 empty .66 69.5 6.2 No No
9 empty 1.95 58.6 7.9 No No
10 empty 1.21 58.9 8.6 No No
2HVJ_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 71.2 12.6 No No
2 empty 2.2 53.5 15.6 No No
3 empty 2.2 61.9 12.8 No No
4 empty .91 67.1 14.4 No No
5 empty 1.25 66.9 10.3 No No
6 empty .98 70.1 8.4 No No
7 empty 1.98 47.7 9.7 No No
8 empty 1.05 60.6 8.1 No No
9 bound 1.65 58.3 9.4 No No
10 empty 1.11 64.6 10.5 No No
4MSW_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.5 56.5 13.9 No No
2 empty 2.12 71.1 12.9 No No
3 empty 1.78 53.4 10.6 No No
4 empty 1.1 65.5 13.4 No No
5 empty .77 77.5 9.2 No No
6 empty 1.03 62.8 11.5 No No
7 empty 1.49 55.1 9.5 No No
8 empty .95 66.2 9.3 No No
9 empty .69 70.8 6.1 No No
10 empty 1.96 59.4 8.7 No No
2HG5_D pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.4 50.9 16.5 No No
2 empty 2.35 56.5 11.2 No No
3 empty .44 57.3 5.2 No No
4 empty .2 61.5 5.3 No No
5 empty 2.98 58.5 5.6 No No
6 empty 1.58 56.4 5 No No
2QTO_D pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 70.5 12.5 No No
2 empty 2.35 55.2 12.7 No No
3 empty 1.61 56.5 9.7 No No
4 empty 1 69.8 9.7 No No
5 empty 1.48 68.2 9.8 No No
6 empty .77 62.1 10.2 No No
7 empty .67 67.9 6.7 No No
8 empty .51 71.7 7.7 No No
9 empty 1.52 68.9 5.9 No No
10 empty 2.17 60.2 5.9 No No
2ITC_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 72 14 Yes No
2 empty 1.97 53.2 11.1 No No
3 empty 2.19 62.6 11.7 No No
4 empty 1.23 64.1 10.6 No No
5 empty .78 76 7.6 No No
6 empty .6 63.3 9.4 No No
7 empty .93 72.4 10.3 No No
8 empty 2.13 53.1 8.2 No No
9 empty 2.77 75.6 8.8 No No
10 empty 1.63 59.8 9.3 No No
5VKH_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.21 61.5 16.3 No No
2 empty 1.69 54.4 9.1 No No
3 empty 2.25 69 12.1 No No
4 empty 2.03 54.3 10.6 No No
5 empty 1.17 70.7 10.5 No No
6 empty .77 70.6 9.7 No No
7 empty .61 65.4 12.3 No No
8 empty .38 69.5 9.3 No No
9 empty 1.86 59.1 7.2 No No
10 empty 1.21 65.9 9 No No
3EFF_L pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 59.1 18.4 No No
2 empty 2.1 70.8 12.6 No No
3 empty 1.5 59.1 17.9 No No
4 empty 2.24 52.2 9.7 No No
5 empty 1.19 65.6 11 No No
6 empty 2.48 73 10 No No
7 empty .86 76.5 7.4 No No
8 empty 1.55 58.3 10 No No
9 empty 2.92 65.4 6.2 No No
10 empty 1.35 53.5 7.7 No No
1J95_A pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.97 69.9 13.1 No No
2 empty 1.86 54.9 13.2 No No
3 empty .82 74.9 11.2 No No
4 empty .78 71 10.9 No No
5 bound 1.47 62.1 8.7 No No
6 empty 1.03 67.7 7.6 No No
7 empty .81 70.2 8 No No
8 empty .69 73.8 6.1 No No
9 empty 1.45 51 6.7 No No
10 empty .97 81.6 4.9 No No
5E1A_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 51.1 13.4 No No
2 empty 2.18 72.8 10.2 No No
3 empty 1.13 64.8 9.9 No No
4 empty 1.41 58.1 9.2 No No
5 empty 1.88 63.2 8.5 No No
6 empty 1.02 61.4 9.9 No No
7 empty 1.26 67.6 8.5 No No
8 empty .75 72.9 10.4 No No
9 empty 2.01 48.9 10.1 No No
10 empty 2.68 76.2 8.9 No No
4LCU_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 56.6 13.2 No No
2 empty 2.09 70.8 16.1 No No
3 empty 2.55 56 11.6 No No
4 empty 1.12 61.9 13.3 No No
5 empty .94 60.6 12.6 No No
6 empty 1.93 50.9 8.4 No No
7 empty .76 77.3 8.6 No No
8 empty 1.46 57.8 8 No No
9 empty 1.07 59.4 11.6 No No
10 empty .92 71.4 9.8 No No
1JVM_B pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.93 67.9 11.6 No No
2 empty 1.98 50.8 14.2 No No
3 empty .87 74.3 11.3 No No
4 empty .81 66.7 6.2 No No
5 empty 1.37 66.1 9.4 No No
6 empty 1.53 59 8.1 No No
7 empty 1.9 61 5.5 No No
8 empty 1.65 68 6.9 No No
9 empty .65 73.3 6.2 No No
10 empty .18 73.6 6.8 No No
2QTO_B pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.99 69.4 12.3 No No
2 empty 2.53 55.3 12.4 No No
3 empty 1.03 68.8 7.6 No No
4 empty 1.65 56.4 10.9 No No
5 empty 1.4 64.7 8.9 No No
6 empty .63 66.1 8.8 No No
7 empty .5 72.4 8.1 No No
8 empty .71 68.8 7.7 No No
9 empty 1.45 64.7 7.1 No No
10 empty 2.21 66.4 6.2 No No
4LBE_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 73.3 10.3 Yes No
2 empty 2.11 55 12.7 No No
3 empty 1.98 53.9 11 No No
4 empty 1.2 64.8 10.5 No No
5 empty .63 62.9 6.9 No No
6 empty 1.44 55.1 11.4 No No
7 empty 1.12 63.8 9.4 No No
8 empty .34 67.3 9.3 No No
9 empty 2.84 71.7 10.1 No No
10 empty 2.08 55.2 7.3 No No
5EC1_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 54 12.5 No No
2 bound 1.33 60.5 18.3 No No
3 empty 2.17 73.4 7.5 No No
4 empty 1.98 62.3 8.1 No No
5 empty 1.43 65.2 7.8 No No
6 empty .66 58.2 12 No No
7 empty .97 64.2 9.8 No No
8 empty .29 70.9 8.5 No No
9 empty 1.04 66.2 8.9 No No
10 empty 2.43 71.5 6.4 No No
2IH3_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.13 67.9 16.5 No No
2 empty 2.37 56.8 11.6 No No
3 empty 2.17 70.5 9.5 No No
4 empty 1.1 63.4 13.5 No No
5 empty .99 60.7 14.9 No No
6 empty 2.27 58.5 10.5 No No
7 empty 1.96 58.7 8.8 No No
8 empty .36 76.4 8.5 No No
9 empty 1.48 63.1 10.6 No No
10 empty 2.85 72.9 8.3 No No
2ITD_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 70.6 12.8 No No
2 empty 2.14 56.6 13.9 No No
3 empty 1.95 54.8 12.2 No No
4 empty 1.2 68 11 No No
5 empty 2.12 45.7 9.4 No No
6 empty .55 60.5 8.8 No No
7 empty 1.55 53.6 10.4 No No
8 empty .9 69.1 7.2 No No
9 empty 1.9 59.7 8.6 No No
10 empty .34 74 7.3 No No
1R3L_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.76 53.6 13 No No
2 empty 1.86 71.3 10.4 No No
3 empty 2.05 52.9 11.5 No No
4 empty 1.16 68.5 10.4 No No
5 empty .99 62.1 9.5 No No
6 empty 1.49 55.8 8.8 No No
7 empty .9 76.9 6.6 No No
8 empty .33 70.8 7.9 No No
9 empty 1.89 57.9 7.8 No No
10 empty 2.78 76.3 9.3 No No
3IFX_A pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.93 74.8 13.1 Yes No
2 empty 1.85 52.5 15.2 No No
3 empty 1.32 63.5 7.8 No No
4 empty 1.14 72.5 7.1 No No
5 empty .61 72 8.4 No No
6 empty 1.5 69 8.8 No No
7 empty .65 75.3 5.8 No No
8 empty .41 74.5 7 No No
9 empty 1.67 58.9 7.8 No No
10 empty 1.64 54.6 7.1 No No
3EFF_K pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.19 64.3 23.9 No No
2 empty 2.05 71.4 14.2 No No
3 empty 1.53 56.6 15.5 No No
4 empty 2.8 55.3 16.5 No No
5 empty 2.36 56.6 8.1 No No
6 empty 2.48 69.5 11.4 No No
7 empty .88 73.9 8.9 No No
8 empty 2.51 48.7 9.9 No No
9 empty 1.67 59.8 8.8 No No
10 empty 1.3 53.1 8.3 No No
3IFX_B pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 76.8 10.9 Yes No
2 empty .65 75 10.9 Yes No
3 empty 2.01 48.3 12.4 No No
4 empty 1.36 70.5 7.3 No No
5 empty 1.54 60.7 10.8 No No
6 empty .69 70.7 9 No No
7 bound 1.38 54.1 8.7 No No
8 empty 2.28 68.4 8.9 No No
9 bound 2.32 63 8.9 No No
10 empty 1.02 68.8 6.3 No No
5VK6_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.34 63 15.6 No No
2 bound 1.4 58.8 17.1 No No
3 empty 2.2 75.1 15.7 No No
4 empty .7 64.2 10.5 No No
5 empty .35 75.3 9.1 No No
6 empty 2.88 77.9 9.5 No No
7 empty .25 66.9 7.8 No No
8 empty 2.29 70.5 5.8 No No
9 empty 1.37 64.4 6.9 No No
10 empty 2.49 55.3 6.1 No No
1R3K_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 73.1 12.5 Yes No
2 empty 1.8 56.5 12 No No
3 empty 1.6 53.8 11.7 No No
4 empty 1.14 68.8 10.4 No No
5 empty .67 60.8 9.3 No No
6 empty 1.51 54.2 9.4 No No
7 empty 1.26 60.3 10.2 No No
8 empty 1.96 59.9 9.4 No No
9 empty 2.54 65.7 6.3 No No
10 empty .34 74.8 7.8 No No
1J95_B pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 70 12.2 No No
2 empty 1.84 55.5 13.9 No No
3 empty .8 75.8 11 No No
4 empty .76 72.7 7.9 No No
5 empty 1.03 66.9 9.2 No No
6 empty 1.5 62.9 8.1 No No
7 empty .83 76.8 6.4 No No
8 empty .9 75 6.2 No No
9 empty 2.75 69.2 5.7 No No
10 empty 1.48 57 5 No No
1J95_D pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 69.7 11.3 No No
2 empty 1.84 56.6 14 No No
3 empty .82 77.2 8.1 No No
4 empty .78 66.7 11.8 No No
5 empty 1.05 67.6 7.2 No No
6 empty 1.4 65.1 7.2 No No
7 empty .82 72.2 7.7 No No
8 empty 2.39 67.7 6.3 No No
9 empty .72 75.2 5.9 No No
10 empty 1.68 52.6 6.7 No No
3OR7_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 70.4 12 No No
2 empty 2.03 53.7 10.3 No No
3 empty .84 69 15.7 No No
4 empty 1.13 66.7 13.9 No No
5 empty .59 65.4 14.1 No No
6 empty .96 63.5 11.5 No No
7 empty 1.51 54.5 9.2 No No
8 empty 2.06 57.9 8.6 No No
9 empty .32 73 7.5 No No
10 empty 1.98 61.7 7.8 No No
1BL8_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 76 14.2 Yes No
2 empty 2.01 50 12.8 No No
3 empty 1.67 54.3 8 No No
4 empty 1.1 73.2 7.4 No No
5 empty .95 69.8 11.6 No No
6 empty 1.57 62.4 7.1 No No
7 empty 1.61 67.5 7.3 No No
8 empty .76 78.8 6.5 No No
9 empty 2.51 62.8 8.5 No No
10 empty .72 70.2 6 No No
2W0F_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.2 59 16.4 No No
2 empty 1.86 73.7 9.6 No No
3 empty 2.29 57.2 13.9 No No
4 bound 1.14 65.6 12.8 No No
5 empty 2.08 52.3 11.4 No No
6 empty .84 75 8.8 No No
7 empty 1.86 65.5 6.2 No No
8 empty 1.18 64.3 8.2 No No
9 empty 1.03 75.6 6.9 No No
10 empty .41 81.3 5.1 No No
2A9H_D pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 73.9 15.8 Yes No
2 empty 1.34 71.9 10 Yes No
3 empty 1.91 54.1 8.3 No No
4 empty 1.81 64.5 10.4 No No
5 empty 1.11 71.2 6.6 No No
6 empty 2.68 55.6 7.6 No No
7 empty .56 59.4 7.5 No No
8 empty .63 75.3 0 No No
9 empty .39 79.5 5.8 No No
10 empty 1.77 55.8 6.4 No No
1BL8_B pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 72.5 14.5 Yes No
2 empty 2.26 53.5 12.3 No No
3 empty 1.7 53.1 10.5 No No
4 empty 1.1 69 7.6 No No
5 empty 1.55 63.5 8.4 No No
6 empty .94 66.2 9.7 No No
7 empty 1.61 69.3 6.2 No No
8 empty .41 72.1 6.5 No No
9 empty 2.51 70.1 8.2 No No
10 empty .84 80.5 0 No No
2QTO_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 71.1 11.3 No No
2 empty 2.56 54.3 12.5 No No
3 empty 1.66 56.9 9.1 No No
4 empty 1.37 65.6 9.8 No No
5 empty .96 71.4 9.6 No No
6 empty .88 68.1 7.7 No No
7 empty .82 74.2 6.6 No No
8 empty .49 72.7 6.7 No No
9 empty 2.09 63.9 8.2 No No
10 empty 1.54 70.9 6.6 No No
2HG5_C pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 59.2 15.9 No No
2 empty .56 59.1 12.1 No No
3 empty 2.33 51.9 12.2 No No
4 empty 1.38 54.1 12.8 No No
5 empty 1.32 69.1 9.7 No No
6 empty 2.53 66.1 5.6 No No
7 empty 1.49 56.4 6.1 No No
8 empty .39 56.9 7.8 No No
9 empty 3.01 63.3 5.3 No No
3EFF_M pH-gated potassium channel KcsA No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.31 63 21.6 No No
2 empty 2.13 72.7 10.5 No No
3 empty 1.68 56.5 17.4 No No
4 empty 2.31 55.3 15.7 No No
5 empty 2.82 55.9 17.6 No No
6 empty .88 73.6 8.4 No No
7 empty 2.34 46 9.4 No No
8 empty 2.13 47.2 10.7 No No
9 empty 1.41 64.4 8 No No
10 empty 1.34 51.4 8.1 No No
3FB6_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 72 13 Yes No
2 empty 1.2 66.1 10.3 No No
3 empty .47 60.6 7.8 No No
4 empty .74 78.7 7.1 No No
5 empty 2.79 76.8 9.2 No No
6 empty 1.67 66.7 7 No No
7 empty 1.99 60.2 8 No No
8 empty 1.29 55 7.2 No No
9 empty 2.76 63.6 6.3 No No
10 empty .35 72.2 5.3 No No
3F5W_C pH-gated potassium channel KcsA Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 73.9 14.7 Yes No
2 empty 1.37 60.7 16.8 No No
3 empty 1.7 59.3 7.9 No No
4 empty .73 66.1 10.5 No No
5 empty 2.75 77.4 9.4 No No
6 empty 2.5 66.4 6.6 No No
7 empty .3 75.2 8.5 No No
8 empty 1.46 63.4 9.1 No No
9 empty .26 72.4 6.3 No No
10 empty 2.89 54.8 6.1 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed68
Domains assessed as druggable using the strict criteria3
Domains assessed as druggable using the relaxed criteria30

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1BL8_C (4134655) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes No
1BL8_D (4134655) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes No
1BL8_B (4134655) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes No
1BL8_D (43655) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å Yes No
1BL8_C (43654) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å Yes No
1BL8_B (43653) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å Yes No
1BL8_A (43652) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å Yes No
1BL8_A (4134655) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes No
1J95_D (4243788) pH-gated potassium channel KcsA UNMATCHED, UNMATCHED, UNMATCHED 1J95 HOMO 2.8Å Yes No
1J95_C (4243788) pH-gated potassium channel KcsA UNMATCHED, UNMATCHED, UNMATCHED 1J95 HOMO 2.8Å Yes No
1J95_A (4243788) pH-gated potassium channel KcsA UNMATCHED, UNMATCHED, UNMATCHED 1J95 HOMO 2.8Å Yes No
1J95_B (4243788) pH-gated potassium channel KcsA UNMATCHED, UNMATCHED, UNMATCHED 1J95 HOMO 2.8Å Yes No
1J95_C (62751) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.8Å Yes No
1J95_B (62750) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.8Å No No
1J95_A (62749) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.8Å No No
1J95_D (62752) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.8Å No No
1JVM_D (67354) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.7Å Yes No
1JVM_C (67353) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.7Å Yes No
1JVM_B (67352) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.7Å No No
1JVM_A (67351) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.7Å Yes No
1JVM_A (4078926) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_C (4078926) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_D (4078926) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_B (4078926) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_A (4064362) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_C (4064362) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_D (4064362) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1JVM_B (4064362) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 2.7Å Yes No
1K4C_C (68130) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2Å Yes No
1K4D_C (68135) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.3Å Yes No
1R3I_C (96923) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.4Å Yes No
1R3J_C (96932) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 1.9Å No No
1R3K_C (96937) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.8Å Yes No
1R3L_C (96942) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.4Å No No
1ZWI_C (125740) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.5Å No No
2A9H_B (144790) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels No No
2A9H_C (144791) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels No No
2A9H_A (144789) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels Yes No
2A9H_D (144792) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels Yes No
2ATK_C (127295) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.48Å No No
2BOB_C (128907) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.75Å Yes No
2BOC_C (128908) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3Å No No
2DWD_C (131849) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.6Å No No
2DWE_C (131850) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.5Å No No
2HG5_D (136393) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.75Å No No
2HG5_C (145295) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.75Å No No
2HJF_C (136540) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.9Å No No
2HVJ_C (136812) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.75Å No No
2HVK_C (136813) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 1.9Å No No
2IH1_C (3120269) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.4Å No No
2IH3_C (3120274) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 1.72Å No No
2ITC_C (137638) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.1Å Yes No
2ITD_C (137639) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.7Å No No
2JK5_C (3130674) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.4Å No No
2NLJ_C (3150462) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.5Å Yes No
2P7T_C (149291) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 2.05Å No No
2QTO_D (151353) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å No No
2QTO_C (151352) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å No No
2QTO_B (151351) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å No No
2QTO_A (151350) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels 3.2Å No No
2QTO_A (4105598) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes Yes
2QTO_C (4105598) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes Yes
2QTO_D (4105598) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes Yes
2QTO_B (4105598) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.2Å Yes Yes
2W0F_C (3230128) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.4Å No No
3EFF_K (3380355) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.8Å No No
3F5W_C (3400274) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.23Å Yes No
3F7V_C (3400419) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.2Å No No
3F7Y_C (3400426) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.4Å No No
3FB5_C (3400612) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.8Å No No
3FB6_C (3400617) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3Å Yes No
3FB7_C (3400622) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.3Å Yes No
3FB8_C (3400627) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.4Å No No
3GB7_C (3430171) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.85Å Yes No
3HPL_C (3460420) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.2Å No No
3IFX_A (3470882) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.56Å Yes No
3IFX_A (4055341) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_C (4055341) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_D (4055341) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_B (4055341) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_D (4006450) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_B (4006450) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_C (4006450) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IFX_A (4006450) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, Voltage-gated potassium channels (Homo Multimer) 3.56Å Yes Yes
3IGA_C (3470898) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.75Å No No
3OGC_C (3650413) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.8Å No No
3OR6_C (3650761) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.7Å Yes No
3OR7_C (3650766) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 2.3Å No No
3PJS_K (3670238) pH-gated potassium channel KcsA Voltage-gated potassium channels, Voltage-gated potassium channels, UNMATCHED 3.8Å No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score