Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

FURIN (P09958) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 03/09/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 03/09/2019)


Chains assessed36
Chains with at least one site assessed as druggable using the strict criteria10
Chains with at least one site assessed as druggable using the relaxed criteria36


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
5JXG_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 66.2 44.9 Yes No
2 empty 2.23 62.4 44.1 No No
3 empty 2.17 70.9 22.6 No No
4 empty 2.09 64.9 27.8 No No
5 empty 1.99 70.1 14 No No
6 empty 2.29 65.5 17.4 No No
7 empty 2.05 75.4 16.4 No No
8 empty 2.11 60.7 17.9 No No
9 empty 2.41 67 11.3 No No
10 empty 2.6 59.6 11.2 No No
6HZD_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 64 33.9 Yes No
2 empty 1.98 63.7 20.6 No No
3 empty 1.94 59.1 17.5 No No
4 bound 2.21 63.2 19.4 No No
5 empty 1.71 63.4 16 No No
6 empty 2.3 53.9 19.6 No No
7 empty 1.74 64.8 14.8 No No
8 empty 2.02 59.8 15 No No
9 empty 2.15 84.8 10 Yes No
10 empty 2.1 63.7 10.8 No No
6HZB_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 63.4 33.9 Yes No
2 empty 1.98 63.5 21.4 No No
3 empty 2.04 57.6 17.2 No No
4 bound 2.24 63.3 19.7 No No
5 empty 1.74 63.3 15.2 No No
6 empty 2.32 53.2 19.3 No No
7 empty 1.74 67.1 13.6 No No
8 empty 1.86 59.3 13.9 No No
9 empty 2.09 59.9 11.8 No No
10 empty 2.27 82.3 10 No No
4OMC_B Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.44 70 20.7 Yes Yes
2 bound 2.39 63.8 29.7 No No
3 empty 2.15 64.3 22.9 No No
4 empty 1.83 61.5 23 No No
5 bound 1.6 63.1 15.8 No No
6 empty 2.19 59.1 21.2 No No
7 empty 2.2 61.8 13.8 No No
8 empty 2.06 55.2 14 No No
9 empty 2.13 56.4 10.2 No No
10 empty 2.43 51.6 12.4 No No
4OMD_E Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 69 46.4 Yes No
2 empty 2.31 63.2 41 No No
3 empty 2.14 69 25.1 No No
4 empty 1.93 66.4 23.1 No No
5 empty 2.21 65.7 12.5 No No
6 empty 2.07 63.5 12.8 No No
7 empty 2.04 67 9.2 No No
8 empty 2.11 72.2 11.1 No No
9 empty 2.28 66.4 10.7 No No
10 empty 1.86 58.7 11.2 No No
5JXI_A Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 66.5 47 Yes Yes
2 empty 2.17 63.2 43.8 No No
3 empty 2.01 64.4 26.8 No No
4 empty 2.31 73.3 21.7 No No
5 empty 2.04 71.8 20.6 No No
6 empty 1.95 70.4 11.2 No No
7 empty 2.52 64.9 13.9 No No
8 empty 1.99 69.1 13.8 No No
9 empty 2.2 59.3 12.3 No No
10 empty 2.38 69.4 9 No No
4OMD_C Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 69.2 46.1 Yes No
2 empty 2.31 62.2 43.5 No No
3 empty 2.04 69.9 22.6 No No
4 empty 1.95 65.4 23.7 No No
5 empty 2.18 67 13.8 No No
6 empty 2.08 66.9 12.9 No No
7 empty 2.02 57.7 18.1 No No
8 empty 2.43 59.7 13.2 No No
9 empty 1.96 70.9 8.3 No No
10 empty 1.81 54.1 11.3 No No
6HZC_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 64.9 33.9 Yes No
2 empty 1.98 64 21.4 No No
3 empty 2 58.9 16.9 No No
4 bound 2.2 62.9 19.9 No No
5 empty 1.74 63.1 15.2 No No
6 empty 2.34 54.2 19.6 No No
7 empty 1.86 65.1 15.4 No No
8 empty 2.08 57.5 14.6 No No
9 empty 2.09 61.2 11.9 No No
10 empty 2.07 80.5 10 No No
4OMD_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 69.4 47.2 Yes No
2 empty 2.27 65.4 31.2 No No
3 empty 2.04 67.1 21.3 No No
4 empty 2.1 70.2 21.8 No No
5 empty 2.19 55.8 20.5 No No
6 empty 2.17 66.1 16.8 No No
7 empty 2.07 67.4 10.1 No No
8 empty 2.08 61.4 17.3 No No
9 empty 2.14 67.6 9.7 No No
10 empty 2.56 64.6 13.5 No No
6EQX_A Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 67.1 50.1 Yes Yes
2 empty 2.12 66.4 32.9 No No
3 empty 2 66.9 29.6 No No
4 empty 1.78 68.4 15.1 No No
5 empty 1.97 67.6 12.3 No No
6 empty 2.29 64.3 17.3 No No
7 empty 2.05 74.3 18.1 No No
8 empty 2.18 58.8 12.5 No No
9 empty 2.5 66.9 11.3 No No
10 empty 1.79 69.5 9.1 No No
5JMO_B Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 65.3 44.1 Yes No
2 empty 2.03 64.4 29.7 No No
3 empty 2.29 65.4 31 No No
4 empty 2.29 70.2 22.7 No No
5 empty 2.49 65.8 28.7 No No
6 empty 2.63 60.2 21.9 No No
7 empty 2.01 67.4 17.2 No No
8 empty 2.69 57.9 20.8 No No
9 empty 2.17 63.3 15.8 No No
10 empty 1.98 61.9 12.5 No No
4RYD_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 68.5 47.3 Yes No
2 bound 2.28 68 28.2 No No
3 empty 2.15 68.5 21.9 No No
4 empty 2 69.1 23 No No
5 empty 2.47 57.5 20.6 No No
6 empty 2.18 65.3 16.6 No No
7 empty 2.4 65.1 11.8 No No
8 empty 2.08 60.6 13.3 No No
9 empty 2.41 66.8 7.6 No No
10 empty 2.56 63.6 9.6 No No
6HZA_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 65.4 33.4 Yes No
2 empty 1.98 64.9 21 No No
3 bound 2.21 66.5 19.2 No No
4 empty 1.94 58.4 16.7 No No
5 empty 1.69 63.3 16.7 No No
6 empty 2.33 53.4 20.5 No No
7 empty 1.85 65.6 14.8 No No
8 empty 1.99 64.6 15.8 No No
9 empty 2.14 62.5 10.9 No No
10 empty 2.11 86.3 9 Yes No
4RYD_D Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 69.2 25.6 Yes Yes
2 empty 1.99 62.5 23.7 No No
3 empty 1.86 61.9 23.5 No No
4 empty 1.92 63.2 21.9 No No
5 bound 1.73 61.2 18.9 No No
6 empty 2.19 55.4 20.9 No No
7 empty 2.07 63.8 14.6 No No
8 bound 2.08 60.1 10.9 No No
9 empty 2.28 60.3 11.2 No No
10 empty 2.15 53.5 12.6 No No
4RYD_E Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 70.2 46 Yes No
2 bound 2.28 64.5 42.6 No No
3 empty 1.89 63.1 31 No No
4 empty 2 66.9 24.2 No No
5 empty 2.24 67.8 12.9 No No
6 empty 2.13 65.2 11.1 No No
7 empty 1.86 75 7.6 No No
8 empty 1.8 69.4 8.9 No No
9 empty 2.09 62.3 13.5 No No
10 empty 2.37 62.4 8.6 No No
6HLB_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 65 32.4 Yes No
2 empty 1.99 63.9 22.3 No No
3 empty 1.9 59.5 17.4 No No
4 empty 2.16 70.3 15.1 No No
5 empty 1.72 63.5 16 No No
6 bound 1.85 70.5 13.5 No No
7 empty 2.23 64.1 18.3 No No
8 empty 2.19 51.1 19.8 No No
9 empty 2.08 60.4 16.3 No No
10 empty 2.11 63.1 13.8 No No
4OMC_C Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 68.2 25.8 Yes No
2 bound 2.2 62.9 30.4 No No
3 empty 2.15 62.9 23.1 No No
4 empty 1.96 60.4 23 No No
5 bound 1.6 64.6 14.3 No No
6 empty 2.25 60.1 15.5 No No
7 empty 2.21 59.3 15.6 No No
8 empty 2.09 60.7 11.6 No No
9 empty 2.12 57.9 11.6 No No
10 empty 2.49 57.9 11.7 No No
6HLD_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 67.8 31.5 Yes No
2 empty 1.97 64.4 21.4 No No
3 empty 1.92 55.4 17.2 No No
4 empty 2.14 73.4 14.9 No No
5 empty 1.72 62.9 15.9 No No
6 bound 1.87 71 14.7 No No
7 empty 1.75 65.6 14.4 No No
8 empty 2.08 59.1 16.6 No No
9 empty 1.79 64.7 12.7 No No
10 empty 2.16 59.7 12.6 No No
4OMC_D Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 60.9 42.6 Yes No
2 bound 2.29 72.6 22.3 No No
3 empty 2.07 65 23.6 No No
4 empty 1.86 60.5 21.6 No No
5 bound 1.59 60.4 17 No No
6 empty 2.17 64.6 13.9 No No
7 empty 2.05 61 11.1 No No
8 empty 2.44 61.2 11.1 No No
9 empty 2.34 59.3 13.9 No No
10 empty 2.14 54.1 12.8 No No
5JMO_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 65.4 46.7 Yes No
2 empty 2.17 65.9 31.6 No No
3 empty 1.9 67.4 29.5 No No
4 empty 2.37 67.1 21.8 No No
5 empty 2.46 66.2 25.9 No No
6 empty 2.08 73.4 19.3 No No
7 empty 2 65.3 18.2 No No
8 empty 2.14 63.5 17 No No
9 empty 2.47 63.1 13.9 No No
10 empty 2.56 61.7 11.1 No No
4RYD_F Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 66.2 46.4 Yes Yes
2 empty 2.08 69.6 24.3 No No
3 empty 1.99 64.6 24.6 No No
4 bound 2.51 62.4 24.1 No No
5 empty 2.02 68.9 18.6 No No
6 empty 2.15 65.8 10.9 No No
7 empty 2.44 65.3 10.2 No No
8 empty 1.77 65.4 10.7 No No
9 empty 2.57 63.6 10.3 No No
10 empty 2.11 58.4 17.6 No No
5MIM_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 64.4 29.8 Yes No
2 bound 2.07 63.4 29.7 No No
3 empty 1.97 64.8 20.5 No No
4 empty 1.95 64.2 17.9 No No
5 empty 2.22 64.1 16.6 No No
6 empty 2.07 65.3 16.3 No No
7 empty 2.08 58.6 12.4 No No
8 empty 2.38 59.2 16.2 No No
9 empty 2.16 83.3 10 No No
10 empty 2.27 46.9 13.3 No No
5JXH_A Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.24 67.3 49.3 Yes Yes
2 empty 2.16 66 42.4 No No
3 empty 1.98 65.8 29.6 No No
4 empty 2.14 66.2 20.6 No No
5 empty 1.92 69.5 12.5 No No
6 empty 2.04 75.8 17.9 No No
7 empty 2.6 61.6 13.8 No No
8 empty 2.04 65 16.9 No No
9 empty 2.16 59.8 14.6 No No
10 empty 2.27 68.8 11.4 No No
4OMD_B Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.24 62.4 43 Yes No
2 empty 2.29 68.5 26.5 No No
3 empty 1.95 63.8 31.5 No No
4 empty 2.22 66.5 24 No No
5 bound 1.71 68.8 16.9 No No
6 empty 2.21 71.4 13.3 No No
7 empty 1.98 78.9 10.8 No No
8 empty 2.16 64.9 14.6 No No
9 empty 2.08 61.1 15.2 No No
10 empty 2.56 66.5 10.6 No No
6EQV_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 64 43.6 Yes No
2 empty 2.14 65.9 29.4 No No
3 empty 1.97 65.4 32.6 No No
4 empty 2.18 72.6 21.2 No No
5 empty 1.89 67 14.9 No No
6 empty 1.97 71 14.1 No No
7 empty 2.32 66.3 17.3 No No
8 empty 2 73.3 15.4 No No
9 empty 2.09 60.3 13.2 No No
10 empty 2.73 66.9 9.7 No No
5JXJ_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 65.9 42.3 Yes No
2 empty 2.28 63.3 42.2 No No
3 empty 2.05 64.5 33.8 No No
4 empty 2.2 70.4 23.2 No No
5 empty 1.91 71.7 14.4 No No
6 empty 2.11 73.3 17.9 No No
7 empty 2.27 61.4 12.1 No No
8 empty 2.63 60.9 11.9 No No
9 empty 2.43 71.8 9.9 No No
10 empty 2.62 72.1 9.2 No No
4OMD_D Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 68 46.6 Yes No
2 empty 2.2 63.1 43.2 No No
3 empty 2.08 69.9 22.8 No No
4 empty 1.9 65.6 22.6 No No
5 empty 2.23 68.7 13 No No
6 empty 2.15 64.1 11 No No
7 empty 2.06 60.4 14.6 No No
8 empty 2.24 58.6 16.8 No No
9 empty 2.36 69.7 10.1 No No
10 empty 1.8 57.3 10.4 No No
4Z2A_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.24 64.2 47.2 Yes No
2 bound 2.17 65.2 24.8 No No
3 empty 1.92 61.5 21 No No
4 empty 1.94 71.5 11.4 No No
5 empty 1.85 63 12.7 No No
6 empty 2.3 59 15.6 No No
7 empty 1.97 50.6 13.4 No No
8 empty 2.44 59 14.9 No No
9 empty 2.5 45.7 11 No No
10 empty 2.05 55.2 12.4 No No
4OMC_E Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 67.1 26 Yes Yes
2 bound 2.15 63.3 30.7 No No
3 empty 1.95 64.1 23.2 No No
4 empty 1.95 54.4 20.2 No No
5 bound 1.61 64.8 14.1 No No
6 empty 2.2 62.9 14 No No
7 empty 1.62 74.6 12.7 No No
8 empty 2.28 61.5 14.5 No No
9 empty 1.97 63.7 13 No No
10 empty 2.09 55.6 10.4 No No
4OMC_A Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 70 25.1 Yes Yes
2 empty 2.07 63.8 22.3 No No
3 empty 1.95 60.4 20.8 No No
4 empty 2.09 60.1 20.2 No No
5 bound 1.6 64.9 15.1 No No
6 empty 2.22 55.7 21.5 No No
7 empty 1.81 61.5 14.3 No No
8 empty 2.27 57.3 14.7 No No
9 empty 2.07 58.9 12.2 No No
10 bound 2.1 57.9 11.9 No No
6EQW_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 66.4 39 Yes No
2 empty 2.21 64.1 44 No No
3 empty 2 66.1 35.4 No No
4 empty 2.27 75.8 21.6 No No
5 empty 2 68.1 12.3 No No
6 empty 2.29 66.5 17.2 No No
7 empty 2.17 59.3 13.4 No No
8 empty 2.69 63.9 11.3 No No
9 empty 2.07 66.7 9.4 No No
10 empty 2.69 64.9 11.1 No No
4OMC_F Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 67.3 28.4 Yes Yes
2 empty 2.08 65.1 22.2 No No
3 empty 1.99 65.1 20.1 No No
4 empty 2.01 55.7 20.3 No No
5 bound 1.6 63.4 16.1 No No
6 empty 2.22 58.6 14.3 No No
7 empty 1.58 69.8 11.9 No No
8 empty 2.18 55.3 16.7 No No
9 empty 2.13 64.1 12.2 No No
10 bound 2.15 62.4 11.6 No No
6HLE_A Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 66.3 42.8 Yes No
2 empty 2.21 61.3 42.3 No No
3 empty 2.03 67 29.1 No No
4 bound 2.38 74.9 21.3 No No
5 empty 2 66.6 21.6 No No
6 empty 2.06 62.9 17.7 No No
7 empty 2.33 62.4 12.2 No No
8 empty 2.52 63.7 14.8 No No
9 empty 1.77 70.1 7.7 No No
10 empty 2.65 63.1 11.4 No No
4RYD_C Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 68.1 43.9 Yes No
2 bound 2.21 63.3 41.3 No No
3 empty 1.95 65.1 31.2 No No
4 empty 2.22 69.2 23.2 No No
5 empty 2.16 67 13.1 No No
6 empty 2.33 67.7 16.2 No No
7 empty 2.24 67.7 12 No No
8 empty 2.47 60.6 10.7 No No
9 empty 2.05 60.3 15.7 No No
10 empty 2.38 68.2 7.1 No No
4OMD_F Furin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 67.9 47.1 Yes No
2 empty 2.36 64.2 40.4 No No
3 empty 1.97 67.6 22.3 No No
4 empty 2.29 68 21.7 No No
5 empty 2.24 63.4 16.2 No No
6 empty 1.98 80.5 10.1 No No
7 empty 2.09 65.7 12.3 No No
8 empty 2.23 62.4 15.5 No No
9 empty 2.65 60.9 18.8 No No
10 empty 2.06 57.9 17.8 No No
4RYD_B Furin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 69.3 43.7 Yes Yes
2 bound 2.23 64.8 44.6 No No
3 empty 1.95 65.3 30.3 No No
4 empty 2.1 66 22.2 No No
5 empty 2.24 72.2 14.3 No No
6 empty 2.15 64.9 13 No No
7 empty 1.84 65.5 17.3 No No
8 empty 2.22 70.8 9.4 No No
9 empty 2.56 67.4 9.3 No No
10 empty 2.46 62.3 12.1 No No
Ligand-based Druggability Score: -0.3
Ligand-based Druggability Score Percentile: 76%
Ligand-based Druggability Help: Help




		
Number of proteins in the network : 13346


FURIN is involved in 32 interactions in the network.


Druggability
Overall Druggability Percentile: 95.25
Druggability for Cancer Therapeutics: 88.32
Druggability for Other Therapeutics: 94.16
Cancer-Associated
Cancer-associated percentile : 81.39
Network Articulation Point
Is FURIN critical for communication in the network?


Detailed Graph Legend:Help