Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

CPB1 (P09955) - Overview - Molecular Target Synopsis

Protein


CPB1, Carboxypeptidase B
Enzyme Classification 3.4.17.2
UniProt P09955

Also Known as CBPB1_PIG, CPB1, CPB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
416P09955-1

Sub-cellular localization


UniProt: CPB1 is active in the following subcellular-locations: secreted.
GO terms: CPB1 is active in the following subcellular-locations: extracellular space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project CPB1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For CPB1 there are:
40 structures (79 chains) solved
32 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


CPB1 has been screened with 31 compounds (48 bioactivities), 16 compounds have bioactivities that show binding affinity of <= 500nM (20 bioactivities). (see details)