Molecular Target Synopsis
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Domains and Structures
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Ligand Efficiency Plot
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ALOX5 (P09917) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (Q2N410) - 3VF1_A 36.72 8.0E-119 2.47Å SUC 2012-05-16
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG1_C 38.99 0 1.85Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3O8Y_A 100 0 2.389Å - 2011-01-19
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG4_D 38.85 0 2.3Å ACD 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3DY5_A 39.42 0 3.5Å HEM 2008-10-07
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V99_B 100 0 2.25Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - 2FNQ_B 39.28 0 3.2Å - 2006-02-28
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG4_C 38.85 0 2.3Å ACD 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V92_A 100 0 2.74Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V99_A 100 0 2.25Å ACD 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 4QWT_A 38.99 0 2Å - 2014-09-24
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V98_B 100 0 2.07Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG4_A 38.85 0 2.3Å ACD 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG4_B 38.85 0 2.3Å ACD 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15 (P12530) - RABBIT 1LOX_A 38.67 3.0E-130 2.4Å RS7 1998-11-04
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_A 41.74 8.0E-120 1.89Å OYP 2012-04-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - 2FNQ_A 39.28 0 3.2Å - 2006-02-28
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 4QWT_D 38.99 0 2Å - 2014-09-24
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 4QWT_B 38.99 0 2Å - 2014-09-24
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V98_A 100 0 2.07Å - 2012-05-02
Lipoxygenase (100%) (view alignment) ALOX12 (P18054) - 3D3L_A 42.32 3.0E-106 2.6Å - 2008-09-09
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15 (P12530) - RABBIT 2P0M_B 38.67 4.0E-130 2.4Å RS7 2007-10-09
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_D 41.74 8.0E-120 1.89Å OYP 2012-04-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG3_D 38.85 0 1.9Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG3_A 38.85 0 1.9Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG1_A 38.99 0 1.85Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3O8Y_B 100 0 2.389Å - 2011-01-19
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG3_C 38.85 0 1.9Å - 2009-08-18
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_B 41.74 8.0E-120 1.89Å OYP 2012-04-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3DY5_C 39.42 0 3.5Å HEM 2008-10-07
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG3_B 38.85 0 1.9Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG1_D 38.99 0 1.85Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15B (O15296) - HUMAN 4NRE_A 42.23 0 2.63Å C8E 2014-02-12
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 4QWT_C 38.99 0 2Å ACD 2014-09-24
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (O16025) - BLACK SEA ROD 3FG1_B 38.99 0 1.85Å - 2009-08-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15 (P12530) - RABBIT 2P0M_A 38.67 4.0E-130 2.4Å - 2007-10-09
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V92_B 100 0 2.74Å - 2012-05-02
Lipoxygenase (100%) (view alignment) ALOX12 (P18054) - 3D3L_B 42.32 3.0E-106 2.6Å - 2008-09-09
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_C 41.74 8.0E-120 1.89Å OYP 2012-04-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) (Q2N410) - 3VF1_B 36.72 8.0E-119 2.47Å SUC 2012-05-16