Molecular Target Synopsis
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GSTA1 (P08263) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 08/10/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 08/10/2019)


Chains assessed91
Chains with at least one site assessed as druggable using the strict criteria82
Chains with at least one site assessed as druggable using the relaxed criteria91


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
1GUH_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 74.9 33.4 Yes Yes
2 empty 2.23 65 24.1 No No
3 empty 2.53 66.2 28.6 No No
4 empty 2.05 63.5 23.1 No No
5 empty 1.59 61.5 11.8 No No
6 empty 2.07 66.7 14.3 No No
7 empty 2.37 68.5 7.3 No No
8 empty 1.83 55.7 14.6 No No
9 empty 2.37 65.2 8.4 No No
10 empty 2.01 58.5 11 No No
1PL2_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.6 66.5 25.1 Yes Yes
2 bound 1.89 76.6 17.4 No No
3 empty 2.05 64.7 20.8 No No
4 empty 1.94 98.6 0 Yes No
5 empty 1.87 58.6 18.4 No No
6 bound 2.3 69.1 13.2 No No
7 empty 2.01 61.8 14.5 No No
8 empty 1.98 66.9 10.3 No No
9 empty 1.72 60.2 10.8 No No
10 empty 2.25 67.4 11.2 No No
1GSE_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 76.7 38.9 Yes Yes
2 empty 2.25 64 24.3 No No
3 empty 1.99 60.9 31.7 No No
4 empty 2.67 70.2 10.7 No No
5 empty 2.55 68 9.7 No No
6 empty 2.17 66.1 12.5 No No
7 empty 2.22 68.3 12.8 No No
8 empty 2.24 74.3 9.8 No No
9 empty 1.75 61.4 11.7 No No
10 empty 1.44 58.9 10.1 No No
3I69_H Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 81.6 21.4 Yes Yes
2 empty 2.15 65.3 24.2 No No
3 empty 2.04 60.9 31.3 No No
4 empty 2 71.4 22.3 No No
5 empty 2.05 78.3 15.1 No No
6 empty 2.7 65 15.1 No No
7 empty 2.28 73.9 11.4 No No
8 empty 2.47 65 12.2 No No
9 empty 1.54 63.5 10.9 No No
10 empty 1.56 62.7 12.3 No No
3I69_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 82.6 30.8 Yes Yes
2 empty 2.11 67.8 25.5 No No
3 empty 2.02 63.5 27.8 No No
4 empty 2.13 55.6 16 No No
5 empty 2.17 71.6 16.1 No No
6 empty 2.67 68.8 12.1 No No
7 empty 1.73 63.5 13 No No
8 empty 2.27 61.9 11.3 No No
9 empty 2.65 69.4 12.2 No No
10 empty 2.24 63.7 11.3 No No
3IK9_F Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 85.3 25 Yes Yes
2 empty 2.04 65.1 33 No No
3 empty 1.94 66.8 22.6 No No
4 empty 2.13 66.3 22.8 No No
5 empty 2.24 70.2 14.1 No No
6 empty 1.76 71.5 16.9 No No
7 empty 1.63 61.4 13 No No
8 empty 2.24 62.3 16.3 No No
9 empty 1.66 55.2 10.2 No No
10 empty 2.25 62.9 11.2 No No
3IK9_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 86.8 26.3 Yes Yes
2 empty 2.14 67.3 22.4 No No
3 empty 1.61 66.7 22.7 No No
4 empty 2.51 64 21 No No
5 empty 1.98 62.8 27.8 No No
6 empty 1.74 75.5 13.4 No No
7 empty 2.21 73.6 12.8 No No
8 empty 2.42 66 13.7 No No
9 empty 1.93 63.7 12.6 No No
10 empty 1.46 57 9.1 No No
3I6A_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 76.2 34.3 Yes Yes
2 empty 2.15 65.6 23.6 No No
3 empty 1.99 61.7 28.9 No No
4 empty 1.69 70.1 14 No No
5 empty 2.69 67.4 14.2 No No
6 empty 2.57 61.6 11.8 No No
7 empty 2 61 12.5 No No
8 empty 2.53 61.4 15.3 No No
9 empty 2.28 62.8 9.2 No No
10 empty 2.1 65.1 9.1 No No
3ZFB_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 73.7 33.3 Yes Yes
2 empty 2.19 67.3 23.3 No No
3 empty 2.04 62 30.2 No No
4 empty 1.75 60.7 12.8 No No
5 empty 2.44 80.9 10.9 No No
6 empty 2.18 68.4 9.1 No No
7 empty 1.74 73.3 12.4 No No
8 empty 1.4 55.2 10.6 No No
9 empty 2.09 74.4 12.1 No No
10 empty 2.61 69.7 7.7 No No
6ATO_B Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 74.9 18.1 Yes No
2 bound 1.7 76.8 15.4 Yes No
3 bound 1.83 92.7 14.2 Yes No
4 empty 1.86 59.8 22.4 No No
5 empty 1.92 53.8 17.1 No No
6 empty 1.87 61.4 18 No No
7 empty 1.93 59.8 12.6 No No
8 empty 1.9 71 8 No No
9 empty 2.2 64.4 9.3 No No
10 empty 1.24 56.3 11.4 No No
1GSF_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.62 68.4 23.1 Yes Yes
2 bound 2.05 76.7 20.3 No No
3 empty 2.1 65 23.8 No No
4 empty 1.93 92.7 15.3 Yes No
5 empty 1.86 61 21.6 No No
6 empty 2.27 57.9 14.8 No No
7 empty 1.97 56.9 16 No No
8 empty 2.05 65.1 11.9 No No
9 empty 1.93 63.2 12.8 No No
10 empty 2.1 60.7 9.5 No No
1YDK_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 76.1 32.2 Yes Yes
2 empty 2.23 69.2 21.6 No No
3 empty 2.06 62.5 31 No No
4 empty 2.05 80.3 10.1 No No
5 empty 2.29 65.6 10.6 No No
6 empty 2.77 69.9 10.6 No No
7 empty 1.83 61.3 12.5 No No
8 empty 1.41 58.9 10.4 No No
9 empty 1.59 58.7 13.5 No No
10 empty 2.21 65.3 9.7 No No
3I69_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 86.6 25.9 Yes Yes
2 empty 2.43 63 23 No No
3 empty 2.06 63.5 34 No No
4 empty 2.1 62.9 20.5 No No
5 empty 2.16 70.1 14.7 No No
6 empty 1.99 71.1 16.8 No No
7 empty 1.73 56.8 16.4 No No
8 empty 1.82 71 10.6 No No
9 empty 2.17 57.6 17.3 No No
10 empty 2.6 65.4 18.8 No No
2R3X_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 76.2 36.1 Yes Yes
2 empty 2.21 66.7 21.2 No No
3 empty 2.15 63.7 30.6 No No
4 empty 2.5 66.5 20.8 No No
5 empty 1.89 68.3 14.6 No No
6 empty 1.49 70.2 10 No No
7 empty 2.48 65.2 15.9 No No
8 empty 2.04 57.1 13.6 No No
9 empty 1.81 70.6 10.1 No No
10 empty 1.81 61.7 9.9 No No
1K3Y_A Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 65.9 25 Yes No
2 bound 1.96 73 18.5 No No
3 bound 1.76 99 0 Yes No
4 empty 2.02 63.6 22.7 No No
5 empty 1.87 59.7 23.1 No No
6 empty 2.38 62.3 12.2 No No
7 empty 1.82 58.3 14.3 No No
8 empty 1.9 64.8 10.9 No No
9 empty 2.45 60.3 9 No No
10 empty 2.07 58.2 10.3 No No
1PKW_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 75.2 37.2 Yes Yes
2 empty 2.31 64.4 23.2 No No
3 empty 2.04 64 21 No No
4 empty 2.11 70.2 16 No No
5 empty 2.31 72.5 18.5 No No
6 empty 2.25 72.9 13.3 No No
7 empty 2.37 64.5 9.5 No No
8 empty 1.63 67 10.5 No No
9 empty 1.31 60.4 9.2 No No
10 empty 2.18 61.4 10.8 No No
3U6V_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 73.8 35.7 Yes Yes
2 empty 2.23 64.5 23.1 No No
3 empty 2.08 64.6 34.4 No No
4 empty 2.23 61.6 14.1 No No
5 empty 1.8 63.1 10.7 No No
6 empty 2.75 65 22.1 No No
7 empty 1.33 58.9 11.4 No No
8 empty 1.71 66.3 10.8 No No
9 empty 2.35 63.3 8.6 No No
10 empty 2.48 71.8 7.6 No No
6ATP_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 76.3 37 Yes Yes
2 empty 2.2 63.7 23.5 No No
3 empty 2.09 64.1 21 No No
4 bound 2.23 73.1 17.3 No No
5 empty 2.32 65.6 11.8 No No
6 bound 1.62 60.2 10.2 No No
7 empty 2.29 61.8 16.6 No No
8 empty 1.43 61.2 9.3 No No
9 empty 2.1 62 10.6 No No
10 empty 1.46 62.1 10 No No
3I6A_F Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 79.1 38.2 Yes Yes
2 empty 2.23 63.6 24.2 No No
3 empty 2.08 62.5 29.5 No No
4 empty 2.31 65.8 22.2 No No
5 empty 1.83 71.9 13.8 No No
6 empty 2.03 63.1 12.8 No No
7 empty 2.49 76.6 10 No No
8 empty 2.14 64 12.6 No No
9 empty 2.61 65.5 11.2 No No
10 empty 1.57 57.5 10.4 No No
1K3O_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 74 36.3 Yes Yes
2 empty 2.19 65.9 22.5 No No
3 empty 2.03 63 19.1 No No
4 empty 2.21 60.8 14.7 No No
5 empty 2.61 66.4 11 No No
6 empty 1.86 68.3 11.4 No No
7 empty 2.46 74.9 13.4 No No
8 empty 1.33 60.1 10.7 No No
9 empty 2.04 66.5 10.9 No No
10 empty 1.85 64.5 9.5 No No
1USB_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 75.8 34.6 Yes Yes
2 empty 2.2 66.5 23.4 No No
3 empty 1.96 71.7 17.4 No No
4 empty 1.97 64.2 22.7 No No
5 empty 2.39 66.5 11.9 No No
6 empty 1.67 65.3 11.5 No No
7 empty 2.34 65.8 14.9 No No
8 empty 2.46 67.9 13.4 No No
9 empty 1.99 55.5 9.3 No No
10 empty 2.11 57.1 8.5 No No
1GSD_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 72.3 35.4 Yes Yes
2 empty 2.1 64 20.7 No No
3 empty 2.06 64.5 30 No No
4 empty 2.53 63.1 20.8 No No
5 empty 2.16 70.8 10.9 No No
6 empty 1.78 65.4 10.7 No No
7 empty 2.26 66.8 7.9 No No
8 empty 1.55 74.1 8.5 No No
9 empty 2.1 56.7 12.4 No No
10 empty 2.1 74.4 6.1 No No
1GSD_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.05 72.3 35.5 Yes Yes
2 empty 2.11 63.1 21.6 No No
3 empty 2.08 60.6 30.2 No No
4 empty 2.55 65.6 20 No No
5 empty 2.24 69.6 10.2 No No
6 empty 1.7 55.6 17.5 No No
7 empty 1.86 61.6 14.3 No No
8 empty 2.31 65 17.4 No No
9 empty 2.08 68.2 7.1 No No
10 empty 1.42 73.1 9.2 No No
3L0H_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 78.3 37.2 Yes Yes
2 empty 2.25 66.3 23.1 No No
3 empty 2.19 62.7 33.6 No No
4 empty 1.69 63.6 14.4 No No
5 empty 2.23 68.5 11.4 No No
6 empty 2.32 75.2 10 No No
7 empty 1.87 62.5 14 No No
8 empty 1.64 99.6 0 Yes No
9 empty 2.21 65.3 8.9 No No
10 empty 1.4 56.6 11.3 No No
3I6A_G Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 78.4 36.6 Yes Yes
2 empty 2.19 65.6 23.4 No No
3 empty 2.21 59.2 24.8 No No
4 empty 1.82 69.5 13 No No
5 empty 2.4 70 18.9 No No
6 empty 2.61 68.1 14.9 No No
7 empty 2.2 73.5 11.3 No No
8 empty 1.86 60.9 11.8 No No
9 empty 2.57 61.9 12.2 No No
10 empty 2.18 69.4 12.4 No No
1GUH_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 76.3 34.2 Yes Yes
2 empty 2.23 65.6 23.4 No No
3 empty 2.5 64.1 33.2 No No
4 empty 2.05 63.1 20.2 No No
5 empty 1.5 67.3 13 No No
6 empty 1.87 66.9 13.3 No No
7 empty 2.41 68.8 10.4 No No
8 empty 1.79 60.3 13.3 No No
9 empty 2.37 62.2 11.3 No No
10 empty 2.15 55.4 10.7 No No
1GSF_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 66.4 23.6 Yes Yes
2 bound 2 76.2 17.1 No No
3 empty 1.98 64.2 22 No No
4 empty 1.93 94.5 13.6 Yes No
5 empty 1.81 60.1 17.2 No No
6 empty 2.29 53.3 16 No No
7 empty 2 58.2 16.3 No No
8 empty 2.04 68.4 11.7 No No
9 empty 1.94 66.2 10 No No
10 empty 1.75 63.1 13.6 No No
3I69_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 77.7 33.3 Yes Yes
2 empty 2.21 65 23.6 No No
3 empty 1.94 61.9 27.8 No No
4 empty 2.6 73 23.8 No No
5 empty 1.64 73.9 13.2 No No
6 empty 1.83 61 14.9 No No
7 empty 2.54 60.7 15.7 No No
8 empty 2.28 62.2 9.7 No No
9 empty 2.43 64.9 11.2 No No
10 empty 1.59 68.4 10.9 No No
6ATQ_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.74 69.8 35.5 Yes Yes
2 empty 1.75 73.9 16 No No
3 empty 1.95 62.8 21.8 No No
4 empty 1.76 96.4 0 Yes No
5 empty 1.82 61.4 19.5 No No
6 bound 2.13 70.5 13.8 No No
7 empty 1.87 65.3 11 No No
8 empty 2.39 57.2 12.1 No No
9 bound 1.3 53.5 11.2 No No
10 empty 2.23 62.6 9.9 No No
1GSD_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 72.8 32.2 Yes Yes
2 empty 2.07 63.7 22.8 No No
3 empty 2.54 66.7 28.7 No No
4 empty 2.05 62.5 30.3 No No
5 empty 1.98 62.8 11.5 No No
6 empty 2.37 66.1 12.7 No No
7 empty 2.06 64 11.5 No No
8 empty 1.56 74.3 8.3 No No
9 empty 1.4 61.4 9.4 No No
10 empty 1.77 52.8 7.5 No No
1PKZ_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 80.9 33.8 Yes Yes
2 empty 2.34 68.2 21.8 No No
3 empty 2.06 63.5 25.1 No No
4 empty 2.58 66.5 21.1 No No
5 empty 1.86 73.2 11.4 No No
6 empty 2.3 69.3 12.9 No No
7 empty 2.17 65.4 15.2 No No
8 empty 2.05 59.5 14.7 No No
9 empty 1.54 64.3 14.1 No No
10 empty 1.91 55.9 15.4 No No
3I6A_E Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 82.5 24.2 Yes Yes
2 empty 1.78 71.6 22.6 No No
3 empty 2.22 66.5 23.6 No No
4 empty 2.06 62.7 20.9 No No
5 empty 2.59 72.5 19.8 No No
6 empty 1.71 70.4 15.1 No No
7 empty 2.27 65.7 12.4 No No
8 empty 2.47 62.3 15.7 No No
9 empty 1.6 64.2 12.3 No No
10 empty 2.37 64.4 10.8 No No
3IK9_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 75.8 36.9 Yes Yes
2 empty 1.95 62.8 30 No No
3 empty 2.23 67.7 17.5 No No
4 empty 1.94 59.4 22.3 No No
5 empty 2.13 72.6 17.8 No No
6 empty 2.63 68.8 12.5 No No
7 empty 1.63 59.9 13.7 No No
8 empty 2 61.4 13.9 No No
9 empty 2.55 65.6 12.9 No No
10 empty 2.29 64.8 15.1 No No
6ATP_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 74.7 33.1 Yes Yes
2 empty 2.22 65.1 23.8 No No
3 empty 1.99 62.2 32.3 No No
4 empty 2.72 66.1 22 No No
5 empty 2.29 66.7 22.7 No No
6 empty 2.22 67.1 8.4 No No
7 empty 1.9 62.7 13.7 No No
8 empty 1.31 56.4 11.3 No No
9 empty 1.65 65.4 13.1 No No
10 empty 2.26 66.7 9.4 No No
2R6K_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 76.5 33.7 Yes Yes
2 empty 2.27 65.5 21.5 No No
3 empty 2.57 65.3 21.9 No No
4 empty 2.12 62.7 31.2 No No
5 empty 1.94 64 21.6 No No
6 empty 1.64 70.4 8.9 No No
7 empty 1.81 64.4 11.1 No No
8 empty 1.42 60.9 10.2 No No
9 empty 2.28 64.8 9.3 No No
10 empty 2.31 65.7 11.8 No No
2R6K_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 77.3 31.9 Yes Yes
2 empty 2.24 65.3 24.2 No No
3 empty 2.12 65.5 29.3 No No
4 empty 1.82 72.1 15.8 No No
5 empty 1.72 61.9 13.3 No No
6 empty 2.64 69.9 10.1 No No
7 empty 2.21 65.5 9.4 No No
8 empty 1.48 57.2 10.5 No No
9 empty 2.35 60.3 14.6 No No
10 empty 1.76 57.5 8.5 No No
3ZFL_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 71.6 32.1 Yes Yes
2 empty 2.27 67.8 22.8 No No
3 empty 2.06 65.7 29.4 No No
4 empty 2.6 69 12.5 No No
5 empty 2.13 62.5 11.7 No No
6 empty 2.11 75.8 12.7 No No
7 empty 2.08 61.1 14.3 No No
8 empty 2.25 68.6 10 No No
9 empty 1.84 58 9.7 No No
10 empty 2.19 62.8 11.4 No No
5JCU_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 75.8 37.2 Yes Yes
2 empty 2.13 64.9 22.5 No No
3 empty 2.11 61.4 30.3 No No
4 empty 2.24 69.9 16.9 No No
5 empty 2.52 67.3 21.8 No No
6 empty 2.42 66.8 19.2 No No
7 empty 2.09 64 16.8 No No
8 empty 2.1 61.5 13.6 No No
9 bound 2.34 64 12.8 No No
10 empty 1.4 55.9 10.8 No No
3KTL_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 78.5 34.2 Yes Yes
2 empty 2.1 62.3 24.2 No No
3 empty 2.08 62.8 32.2 No No
4 empty 2.13 61.5 15.6 No No
5 empty 2.02 59.9 12.3 No No
6 empty 2.37 78.1 7.6 No No
7 empty 2.3 63.7 16 No No
8 empty 2.51 62.8 14.2 No No
9 empty 1.35 62.6 10.9 No No
10 empty 2.3 64 10.3 No No
3Q74_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 74.5 34.5 Yes Yes
2 empty 2.2 66.1 23.4 No No
3 empty 1.98 65.8 17.3 No No
4 empty 2.61 67.5 18.2 No No
5 empty 2.44 72.6 9.5 No No
6 empty 2.67 68 15.2 No No
7 empty 1.56 64 10.9 No No
8 empty 2.7 70 9.7 No No
9 empty 2.28 63 9.9 No No
10 empty 1.71 70.4 9.8 No No
3I6A_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 78.5 38.5 Yes Yes
2 empty 2.15 65.4 23 No No
3 empty 2.01 65.3 18.3 No No
4 empty 1.72 71.4 15.6 No No
5 empty 2.6 74.2 9.2 No No
6 empty 1.96 61.3 11.1 No No
7 empty 2.41 63.6 15.4 No No
8 empty 2.4 72.8 11.2 No No
9 empty 2.57 67.6 7.9 No No
10 empty 2.14 63.9 13.2 No No
1GUH_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 76.6 33.8 Yes Yes
2 empty 2.21 64.5 23.5 No No
3 empty 2.52 65.5 28.8 No No
4 empty 2.02 60.9 23.4 No No
5 empty 1.75 64.3 10.4 No No
6 empty 2.21 64.5 14.1 No No
7 empty 2.38 68.4 8.4 No No
8 empty 2.36 60.1 11.1 No No
9 empty 2.17 54.2 10.9 No No
10 empty 1.76 67.2 10.8 No No
3I69_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 78.5 39.1 Yes Yes
2 empty 2.14 67.4 23.3 No No
3 empty 2.09 64.3 27.6 No No
4 empty 2.57 77.2 10.6 No No
5 empty 1.72 72.2 14.1 No No
6 empty 1.93 63.2 10.7 No No
7 empty 2.5 74.4 10.2 No No
8 empty 2.46 67.4 11.6 No No
9 empty 2.31 66.8 11.8 No No
10 empty 2.57 62.3 11.1 No No
1K3Y_B Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 72.6 19.3 Yes No
2 empty 1.62 73.2 17.3 Yes No
3 empty 1.8 96.2 0 Yes No
4 empty 1.79 60.8 23.1 No No
5 empty 1.96 66.4 14.4 No No
6 empty 1.91 59 20.3 No No
7 empty 2.33 55.7 13.6 No No
8 empty 1.76 56.5 15.9 No No
9 empty 1.31 57.3 10.2 No No
10 empty 2.17 59.7 12 No No
5LCZ_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.42 68.9 29.8 Yes Yes
2 empty 2.34 65 35.7 No No
3 empty 2.42 72 15.8 No No
4 empty 2.19 61.5 16.5 No No
5 empty 2.54 64 14.9 No No
6 empty 2.75 63.2 14.2 No No
7 empty 2.17 64.1 9.8 No No
8 empty 1.75 64.9 10.9 No No
9 empty 2.05 58.9 10.3 No No
10 empty 2.18 72.1 9.1 No No
1XWG_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.2 76.1 37.6 Yes Yes
2 empty 2.26 66.9 22.4 No No
3 empty 1.86 63.4 31.1 No No
4 empty 1.99 70.9 14 No No
5 empty 2.77 69.2 9.9 No No
6 empty 2.32 69 10.8 No No
7 empty 2.25 64.9 8.7 No No
8 empty 2 60.6 12.4 No No
9 empty 1.53 63.3 11.9 No No
10 empty 2.28 66.4 8.3 No No
1K3L_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 76.3 33.4 Yes Yes
2 empty 2.19 67.9 23.1 No No
3 empty 2.52 64.4 23.5 No No
4 empty 2.02 62.6 27.4 No No
5 empty 1.96 68.7 14.3 No No
6 empty 1.44 69.6 10.2 No No
7 empty 2.34 68.9 11.2 No No
8 empty 2.04 65.1 11.3 No No
9 empty 1.41 56.9 10.4 No No
10 empty 2.29 61.9 12.8 No No
3ZFB_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 72.9 30.6 Yes Yes
2 empty 2.4 64.4 34.8 No No
3 empty 2.32 69 22.2 No No
4 empty 2.13 67.2 10.9 No No
5 empty 1.72 70.5 8.8 No No
6 empty 1.64 64.4 10.7 No No
7 empty 2.4 69.3 11.8 No No
8 empty 1.39 59.6 10.4 No No
9 empty 2.32 62.6 12.4 No No
10 empty 1.6 55.8 8.5 No No
3I69_F Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 83.6 24.9 Yes Yes
2 empty 1.9 65 22.5 No No
3 empty 2.38 62.3 25.3 No No
4 empty 1.94 60.3 16.6 No No
5 empty 2.06 60.5 23.3 No No
6 empty 1.86 77.2 12.3 No No
7 empty 2.24 73.3 12.6 No No
8 empty 1.9 63.6 12.2 No No
9 empty 2.9 67.4 14.2 No No
10 empty 2.14 62 12.4 No No
1YDK_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 72.5 34.2 Yes Yes
2 empty 2.16 63.4 24.1 No No
3 empty 2.24 66.1 31.6 No No
4 empty 2.6 64.5 19.2 No No
5 empty 1.99 64.3 11.7 No No
6 empty 1.43 63.4 11.7 No No
7 empty 1.77 67.2 9.2 No No
8 empty 2.31 71.9 13.4 No No
9 empty 1.46 57.4 9.3 No No
10 empty 2.08 53.4 8.6 No No
1GSD_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 72.7 31.5 Yes Yes
2 empty 2.04 65.3 22.1 No No
3 empty 2.01 64.4 30.2 No No
4 empty 2.6 64.6 18.9 No No
5 empty 2.18 71.4 10.4 No No
6 empty 1.93 59 12.9 No No
7 empty 2.46 65.6 7.6 No No
8 empty 1.42 73.9 9.6 No No
9 empty 1.73 48.3 8.4 No No
10 empty 2.01 66.7 5.9 No No
5LD0_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 74.5 29.7 Yes Yes
2 empty 2.07 64.9 23.6 No No
3 empty 2.15 60.8 22.8 No No
4 empty 2.83 68.5 21.4 No No
5 empty 2.3 73.1 14.3 No No
6 empty 2.36 60.8 18.5 No No
7 empty 1.78 62.7 10.9 No No
8 empty 1.34 58.4 11 No No
9 empty 2.4 74.3 9 No No
10 empty 2.03 49.4 8.2 No No
1K3O_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 73.9 34.3 Yes Yes
2 empty 2.06 65.9 30.3 No No
3 empty 2.13 68.2 17.5 No No
4 empty 2.58 67.8 18 No No
5 empty 2.12 61.1 15.9 No No
6 empty 2.3 62.3 11.5 No No
7 empty 2.17 65.5 9.5 No No
8 empty 1.64 63.8 12.8 No No
9 empty 2.21 68.6 10 No No
10 empty 2.23 57.3 12.5 No No
1PL2_B Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 65 25 Yes No
2 bound 2.04 74.3 19.3 No No
3 empty 1.95 97.8 0 Yes No
4 empty 1.94 62 21.3 No No
5 empty 2.06 55.5 14.9 No No
6 empty 2.52 65.4 11.4 No No
7 empty 1.92 61.6 10.9 No No
8 empty 2.12 62.6 10.7 No No
9 empty 1.45 53.3 12.5 No No
10 empty 2.13 83.2 9.5 No No
1USB_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 79.6 33.4 Yes Yes
2 empty 2.24 67.4 22.2 No No
3 empty 1.92 62 20.9 No No
4 empty 1.99 67.6 18.4 No No
5 empty 2.39 67.4 12.7 No No
6 empty 2.1 61.6 12.5 No No
7 empty 2.25 66.1 9.3 No No
8 empty 1.48 65.4 13.3 No No
9 empty 2.56 71.8 9.8 No No
10 empty 2.08 59.5 16.6 No No
4HJ2_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 78.1 36.4 Yes Yes
2 empty 2.14 68.2 21.2 No No
3 empty 2.17 62.6 31.3 No No
4 empty 2.02 63.4 15.1 No No
5 empty 1.91 61.5 13.2 No No
6 empty 2.39 64.7 9.1 No No
7 empty 2.45 70 10.1 No No
8 empty 2.33 65.9 15.5 No No
9 empty 1.5 69.2 8.6 No No
10 empty 2.03 74 8.2 No No
6ATO_A Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.77 64.1 25.1 Yes No
2 empty 2.18 62.5 24.2 No No
3 bound 1.86 76.4 16.7 No No
4 empty 1.77 98.6 0 Yes No
5 empty 1.76 59.6 18.4 No No
6 empty 2.01 63.4 17.3 No No
7 bound 2.49 71.3 10.1 No No
8 empty 2.2 56.6 12.6 No No
9 bound 2.17 66 11.3 No No
10 bound 1.42 55.8 11.6 No No
3U6V_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 75.3 33.4 Yes Yes
2 empty 2.22 67.4 22.5 No No
3 empty 2 61.1 32.9 No No
4 empty 2.79 67.5 13.2 No No
5 empty 2.26 59.3 13.1 No No
6 empty 1.82 60.8 14.8 No No
7 empty 2.41 65.9 12.8 No No
8 empty 2.13 70.3 9.2 No No
9 empty 1.41 55.3 9 No No
10 empty 1.88 58.7 8.3 No No
1GUH_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 74.7 34 Yes Yes
2 empty 2.26 64.5 23.8 No No
3 empty 2.48 67.8 27 No No
4 empty 2.1 61.2 28.4 No No
5 empty 1.91 63.7 15.2 No No
6 empty 2.4 68.9 13.6 No No
7 empty 2.41 68.8 7.8 No No
8 empty 2.49 68.4 10.1 No No
9 empty 1.81 56.5 15.5 No No
10 empty 2.01 54.5 11 No No
1PKW_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 76.8 37.1 Yes Yes
2 empty 2.2 67.6 22.6 No No
3 empty 2.16 63.5 31.8 No No
4 empty 2.72 74.6 16.5 No No
5 empty 2.02 68.8 11.9 No No
6 empty 2.09 67.3 11.4 No No
7 empty 1.64 65 12.2 No No
8 empty 2.22 70.9 10.5 No No
9 empty 1.48 60.3 9.8 No No
10 empty 2.25 66.5 9.9 No No
5JCU_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 76.9 34 Yes Yes
2 empty 2.2 67.5 21.7 No No
3 empty 2.13 64.3 21.7 No No
4 empty 2.48 65.4 21.1 No No
5 empty 2.09 66.2 16.3 No No
6 empty 2.36 76.1 13.3 No No
7 empty 1.65 64.3 10.7 No No
8 empty 2.29 64.9 13.1 No No
9 empty 1.35 57.9 8.6 No No
10 empty 2.03 71 7.4 No No
6ATR_B Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 74 19.6 Yes No
2 bound 1.85 74.7 15.6 No No
3 bound 1.82 97.4 0 Yes No
4 empty 1.89 60.8 22.6 No No
5 empty 2.06 69 13.5 No No
6 empty 1.84 54 16.2 No No
7 empty 1.9 58.8 13.4 No No
8 empty 1.99 64.9 10.3 No No
9 empty 1.86 57.9 12.5 No No
10 empty 1.77 53 12.1 No No
2R3X_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 79.5 30.6 Yes Yes
2 empty 1.92 65.9 14 No No
3 empty 1.78 60.2 19.5 No No
4 empty 2.13 60.9 12.9 No No
5 empty 1.93 63 10.9 No No
6 empty 1.73 56.6 11.3 No No
7 empty 1.85 60.4 12.3 No No
8 empty 2.12 66 9 No No
9 empty 2.62 62.3 8.3 No No
10 empty 2.08 61.7 9.9 No No
1PL1_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.66 67.3 24.5 Yes Yes
2 bound 1.98 73.3 17 No No
3 empty 2.11 62 21.9 No No
4 empty 1.83 98.6 0 Yes No
5 empty 1.8 59.2 14.3 No No
6 empty 2.04 60.7 16.1 No No
7 empty 1.96 64.6 10.6 No No
8 empty 2.42 61.6 10.5 No No
9 empty 2.19 64.9 10.4 No No
10 empty 1.72 51.6 11.5 No No
1GSE_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 75.9 38.2 Yes Yes
2 empty 2.29 66.8 22.7 No No
3 empty 2.54 67.2 22.3 No No
4 empty 2.08 63.1 22.5 No No
5 empty 2.01 65.1 18.2 No No
6 empty 2.41 68.4 9 No No
7 empty 1.79 64.6 13.2 No No
8 empty 2.22 67.6 10 No No
9 empty 1.75 57.8 10.8 No No
10 empty 1.92 77 10.5 No No
3L0H_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 76.5 36.7 Yes Yes
2 empty 2.11 61.7 31.8 No No
3 empty 2.24 68.3 21.3 No No
4 empty 2.56 64.8 20.3 No No
5 empty 1.96 61 16.2 No No
6 empty 1.76 72.4 9.5 No No
7 empty 2.38 61.2 15.3 No No
8 empty 2.24 61.3 11.4 No No
9 empty 2.19 65.8 11.4 No No
10 empty 1.73 98.7 0 Yes No
3IK9_G Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 78.9 32.9 Yes Yes
2 empty 1.89 62.7 31.7 No No
3 empty 1.98 61.5 19.5 No No
4 empty 2.21 76.3 13 No No
5 empty 2.83 75.2 11 No No
6 empty 1.89 76.9 11.3 No No
7 empty 1.94 59.2 12.4 No No
8 empty 2.23 70.3 9.3 No No
9 empty 2.49 68.2 11.5 No No
10 empty 1.6 52.7 9.3 No No
1GSF_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.65 67.8 23.4 Yes Yes
2 bound 1.86 79.9 17.9 Yes Yes
3 empty 2.04 65.3 22 No No
4 empty 2.06 96.3 13.2 Yes No
5 empty 1.98 58.2 26.6 No No
6 empty 1.99 57.1 16.5 No No
7 empty 1.99 63.2 11.8 No No
8 empty 2.34 68 11.8 No No
9 empty 2.21 52 13.5 No No
10 empty 1.93 63.6 11.1 No No
3I6A_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 77.4 37.9 Yes Yes
2 empty 2.09 60.8 28.8 No No
3 empty 2.11 63.8 21.8 No No
4 empty 2.23 69.8 14.2 No No
5 empty 2.73 68.4 12.5 No No
6 empty 2.67 70.8 14.6 No No
7 empty 1.95 73.2 12.3 No No
8 empty 2.52 61.1 13.8 No No
9 empty 2.61 60.9 11.5 No No
10 empty 1.82 64.8 10.8 No No
3IK9_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 78.4 33.7 Yes Yes
2 empty 2.12 66.6 21.5 No No
3 empty 2.03 66.1 27.7 No No
4 empty 2.69 72.5 9.1 No No
5 empty 1.84 79.4 10.4 No No
6 empty 1.75 63.9 11.9 No No
7 empty 2.27 78.3 9.6 No No
8 empty 2.35 64.4 15.5 No No
9 empty 2.22 61.1 13.4 No No
10 empty 2.37 67.6 12.2 No No
3IK9_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 79.6 34 Yes Yes
2 empty 2.14 65 24.8 No No
3 empty 2.08 61.4 30.7 No No
4 empty 1.71 76.5 13.5 No No
5 empty 2.27 74.1 10.8 No No
6 empty 2.69 68 12.3 No No
7 empty 2.51 63.3 12.6 No No
8 empty 1.59 61.8 15.8 No No
9 empty 2.55 66.7 14.6 No No
10 empty 2.17 68.2 11.4 No No
5JCU_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 74.7 35.4 Yes Yes
2 empty 2.1 63.3 22.6 No No
3 empty 2.57 66.9 28.5 No No
4 empty 2.1 64.8 24 No No
5 empty 2.18 70.5 16.4 No No
6 empty 1.81 64.4 10.6 No No
7 empty 2.33 66.8 13.5 No No
8 empty 2.35 61.8 12.1 No No
9 empty 1.31 58.3 9.7 No No
10 empty 2.08 61.6 9.4 No No
3IK9_H Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 86 24.9 Yes Yes
2 empty 2.58 64.4 21.7 No No
3 empty 2.03 64.7 30.3 No No
4 empty 1.91 60.9 19.4 No No
5 empty 2.14 68.8 14.5 No No
6 empty 1.77 73.2 13.4 No No
7 empty 1.73 72.8 9.2 No No
8 empty 2.25 64.7 19.1 No No
9 empty 1.96 52.7 18.8 No No
10 empty 2.19 60.2 9.9 No No
3I6A_D Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 79.9 33.2 Yes Yes
2 empty 2.57 68.4 29.2 No No
3 empty 2.03 62.4 21.4 No No
4 empty 2.2 69.3 15.5 No No
5 empty 2.01 63.6 17.9 No No
6 empty 1.69 74.8 13.7 No No
7 empty 2.47 62.3 15.7 No No
8 empty 1.65 59.9 13.9 No No
9 empty 2.31 46.1 10 No No
10 empty 1.43 63.6 8.8 No No
3KTL_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 77.6 36.8 Yes Yes
2 empty 2.35 67.5 22.6 No No
3 empty 2 60.6 31.7 No No
4 empty 2.72 65.7 21.3 No No
5 empty 2.07 65.8 15.7 No No
6 empty 2.22 67.5 14.6 No No
7 empty 1.69 69.7 13.3 No No
8 empty 1.64 60.8 12.3 No No
9 empty 1.38 59.3 11 No No
10 empty 2.17 67 10.8 No No
3I69_G Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 75.6 34.2 Yes Yes
2 empty 2.2 67.8 21.6 No No
3 empty 2.02 61.7 24.8 No No
4 empty 1.71 75.5 12.5 No No
5 empty 2.69 68.4 13.7 No No
6 empty 1.89 61 15.6 No No
7 empty 2.49 66.4 16.1 No No
8 empty 2.39 64.5 11.9 No No
9 empty 2.37 71.8 9.9 No No
10 empty 1.89 52.5 11.6 No No
5JCU_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 74.5 36.8 Yes Yes
2 empty 2.16 65.1 23 No No
3 empty 2.04 62.6 31.1 No No
4 empty 2.76 71.7 19.6 No No
5 empty 2.15 68.9 15.8 No No
6 empty 2.27 62 16.7 No No
7 empty 1.4 61.8 10.8 No No
8 empty 1.62 61.3 10.3 No No
9 empty 2.3 65.2 7.3 No No
10 empty 1.36 56.7 9 No No
1PKZ_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 73.1 38.4 Yes Yes
2 empty 2.3 65.8 22.4 No No
3 empty 2.09 64.7 18.7 No No
4 empty 2.51 69.4 14.3 No No
5 empty 2.35 72.6 18.1 No No
6 empty 2.4 69.4 11.2 No No
7 empty 1.81 63.3 10.7 No No
8 empty 2.26 67.7 11.6 No No
9 empty 1.94 59.6 9.6 No No
10 empty 1.44 57.4 8.9 No No
1XWG_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.2 74.6 38.2 Yes Yes
2 empty 2.23 62.9 23.7 No No
3 empty 2.09 62.9 26.1 No No
4 empty 2.56 69.8 22.3 No No
5 empty 2.5 73 19 No No
6 empty 1.92 62.9 13.7 No No
7 empty 1.61 65.1 10.4 No No
8 empty 1.72 65.4 13.5 No No
9 empty 1.64 56.5 9.9 No No
10 empty 2.3 60.2 11.7 No No
3I69_E Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 83.6 29.2 Yes Yes
2 empty 2.2 66.2 23.8 No No
3 empty 2.08 60.3 31.4 No No
4 empty 2.5 68.6 24.2 No No
5 empty 2.37 73 17.3 No No
6 empty 1.8 62.8 14.9 No No
7 empty 1.45 60.3 12.8 No No
8 empty 2.45 65 14.3 No No
9 empty 1.6 59.6 11.7 No No
10 empty 1.62 55.8 9.9 No No
3I6A_H Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 78.9 38.1 Yes Yes
2 empty 2.09 65.6 24.1 No No
3 empty 2.05 62.5 34.5 No No
4 empty 2.05 68.3 17.5 No No
5 empty 2.77 67.2 12.3 No No
6 empty 2.7 65.8 12.5 No No
7 empty 1.76 66.8 10.7 No No
8 empty 1.62 61.4 13.4 No No
9 empty 2.29 66.9 12.5 No No
10 empty 2.44 64.9 14.1 No No
3IK9_E Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 77.6 37.8 Yes Yes
2 empty 2.15 66 24.4 No No
3 empty 2.04 59.8 26.8 No No
4 empty 1.78 73.3 13.3 No No
5 empty 2.4 67.1 11.6 No No
6 empty 1.96 60.9 13.6 No No
7 empty 2.48 66.1 16 No No
8 empty 2.18 70.6 9.8 No No
9 empty 1.9 59 10 No No
10 empty 2.76 68.6 8.3 No No
3ZFL_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 70.7 35.5 Yes Yes
2 empty 2.21 65.9 22.4 No No
3 empty 2.01 62.7 27.6 No No
4 empty 2.68 74.7 11.4 No No
5 empty 2.1 66.6 11.1 No No
6 empty 2.04 61.3 12.7 No No
7 empty 2.17 73.8 10.5 No No
8 empty 2.75 67.2 11.8 No No
9 empty 1.71 70.3 11.4 No No
10 empty 1.46 54 11.4 No No
3Q74_A Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 70.9 35.2 Yes Yes
2 empty 2.19 66.8 22.6 No No
3 empty 2 61.5 30.1 No No
4 empty 2.41 62.5 11.4 No No
5 empty 2.24 79.8 10.9 No No
6 empty 2.23 62.2 13.5 No No
7 empty 2.71 76.7 10.8 No No
8 empty 1.83 65.6 12.3 No No
9 empty 1.42 55.4 9.8 No No
10 empty 1.51 69.5 9.2 No No
4HJ2_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 78.6 33.3 Yes Yes
2 empty 2.29 67.6 23.4 No No
3 empty 2.08 61.6 30.8 No No
4 empty 1.85 59.1 15 No No
5 empty 1.84 68.4 11 No No
6 empty 2.69 64.8 15.7 No No
7 empty 2.32 67.1 10.7 No No
8 empty 2.12 69.8 13 No No
9 empty 2.08 67 10.4 No No
10 empty 2.33 68.9 10 No No
6ATR_A Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 73.2 17.6 Yes No
2 bound 2.02 62.1 22.7 No No
3 bound 1.74 77 15.8 No No
4 bound 1.79 96.2 0 Yes No
5 empty 1.82 59.1 20.2 No No
6 empty 2.01 63.2 21.9 No No
7 empty 1.71 52.3 16.3 No No
8 bound 2.26 59.2 13 No No
9 empty 2 66 10.6 No No
10 empty 2.49 58.8 12.9 No No
1GSF_C Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 83.3 27.2 Yes Yes
2 empty 1.61 66.1 22.8 No No
3 empty 1.82 60.2 20.5 No No
4 empty 1.93 69.8 15.8 No No
5 empty 1.91 58.9 18.9 No No
6 empty 2.26 55 14.5 No No
7 empty 1.98 60.6 15.9 No No
8 empty 2.1 64.4 12.6 No No
9 empty 2.58 61.2 9.1 No No
10 empty 1.4 56.4 12.2 No No
1PL1_B Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 64.9 25 Yes No
2 bound 2.03 75.6 18.9 No No
3 empty 1.89 97.9 0 Yes No
4 empty 1.93 59.9 21.8 No No
5 empty 2.64 60.3 16.3 No No
6 empty 2.02 69.4 16.1 No No
7 empty 1.9 58.8 17.4 No No
8 empty 2.02 61.8 12.9 No No
9 empty 1.97 58.6 10.4 No No
10 empty 1.81 49.2 11.8 No No
5LCZ_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 72.2 30.8 Yes Yes
2 empty 2.28 65 35.5 No No
3 empty 2.23 72.3 14.4 No No
4 empty 2.17 61.7 17.7 No No
5 empty 2.42 70.2 11.8 No No
6 empty 2.43 66.6 9.7 No No
7 empty 2.29 75.6 12.4 No No
8 empty 1.92 61.5 17.7 No No
9 empty 1.54 60.9 11.9 No No
10 empty 2.13 70.6 8.5 No No
6ATQ_B Glutathione S-transferase A1 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 77.1 19.6 Yes No
2 empty 1.71 74.4 17 Yes No
3 empty 1.94 64.5 18.9 No No
4 empty 2.03 59.5 24.5 No No
5 empty 1.75 97.8 0 Yes No
6 empty 1.75 53.1 16.4 No No
7 empty 1.73 56.8 17.1 No No
8 empty 2.56 57.9 12 No No
9 empty 2 61.3 10.1 No No
10 empty 1.76 60.2 13 No No
1K3L_B Glutathione S-transferase A1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 75.7 37 Yes Yes
2 empty 2.15 65.1 25.3 No No
3 empty 2.07 63 31.1 No No
4 empty 2.02 63.8 24.1 No No
5 empty 2.21 66.9 9.9 No No
6 empty 2.34 71.9 6.8 No No
7 empty 2.05 60.6 13.5 No No
8 empty 1.42 58.6 10.2 No No
9 empty 2.3 65.3 9.1 No No
10 empty 2.51 63.5 7.4 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed119
Domains assessed as druggable using the strict criteria47
Domains assessed as druggable using the relaxed criteria95

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1GSD_B (4021033) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSD_A (17669) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes No
1GSD_C (118475) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å No No
1GSD_D (118476) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes Yes
1GSD_C (4072374) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSD_D (4072374) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSD_B (17670) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes Yes
1GSD_A (32963) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å No No
1GSD_B (32964) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å No No
1GSD_A (4021033) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSD_C (118474) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes Yes
1GSD_D (118477) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å Yes Yes
1GSE_A (4256296) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2Å Yes Yes
1GSE_B (4256296) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2Å Yes Yes
1GSE_B (17668) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2Å Yes No
1GSE_B (32962) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2Å No No
1GSE_A (17667) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2Å Yes No
1GSE_A (32961) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2Å No No
1GSF_B (17674) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes No
1GSF_C (4255639) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSF_D (4255639) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSF_A (4206894) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSF_B (4206894) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.5Å Yes Yes
1GSF_A (17673) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes No
1GSF_D (118481) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å Yes No
1GSF_D (118480) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes No
1GSF_C (118479) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å Yes No
1GSF_C (118478) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.5Å Yes No
1GSF_B (32968) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å Yes No
1GSF_A (32967) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.5Å Yes No
1GUH_A (4206569) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.6Å Yes Yes
1GUH_B (4206569) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.6Å Yes Yes
1GUH_C (4259223) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.6Å Yes Yes
1GUH_D (4259223) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.6Å Yes Yes
1GUH_D (118484) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.6Å Yes No
1GUH_D (118485) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.6Å Yes No
1GUH_C (118482) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.6Å Yes No
1GUH_B (32966) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.6Å Yes No
1GUH_A (32965) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.6Å Yes No
1GUH_A (17671) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.6Å Yes No
1GUH_B (17672) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.6Å Yes Yes
1GUH_C (118483) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.6Å Yes No
1K3L_B (4186074) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.5Å Yes Yes
1K3L_B (77231) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.5Å Yes No
1K3L_A (77230) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.5Å No No
1K3L_A (77229) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.5Å Yes No
1K3L_B (77232) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.5Å Yes No
1K3L_A (4186074) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.5Å Yes Yes
1K3O_A (77233) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.8Å Yes Yes
1K3O_A (77234) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.8Å No No
1K3O_B (77235) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.8Å Yes Yes
1K3O_B (77236) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.8Å No No
1K3O_B (4255685) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.8Å Yes Yes
1K3O_A (4255685) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.8Å Yes Yes
1K3Y_B (77247) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.3Å Yes No
1K3Y_A (77246) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.3Å No No
1K3Y_A (77245) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.3Å Yes No
1K3Y_B (77248) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.3Å Yes No
1K3Y_B (4143068) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.3Å Yes Yes
1K3Y_A (4143068) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.3Å Yes Yes
1PKW_A (4064815) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2Å Yes Yes
1PKW_A (104171) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2Å Yes No
1PKW_A (104170) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2Å Yes No
1PKW_B (104173) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2Å Yes No
1PKW_B (104172) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2Å Yes No
1PKW_B (4064815) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2Å Yes Yes
1PKZ_B (104176) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.1Å Yes Yes
1PKZ_B (104177) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.1Å No No
1PKZ_A (104175) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.1Å No No
1PKZ_A (104174) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.1Å Yes No
1PKZ_A (4086956) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
1PKZ_B (4086956) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
1PL1_A (104179) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.75Å Yes No
1PL1_B (104181) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.75Å Yes No
1PL1_B (104180) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.75Å Yes No
1PL1_A (4200988) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.75Å Yes Yes
1PL1_B (4200988) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.75Å Yes Yes
1PL1_A (104178) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.75Å Yes No
1PL2_B (104184) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.8Å Yes No
1PL2_A (104183) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.8Å Yes No
1PL2_A (104182) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.8Å Yes No
1PL2_B (104185) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.8Å Yes No
1PL2_B (4216554) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.8Å Yes Yes
1PL2_A (4216554) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.8Å Yes Yes
1USB_B (4139703) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.07Å Yes Yes
1USB_A (4139703) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.07Å Yes Yes
1USB_A (108002) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.07Å No No
1USB_B (108004) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.07Å No No
1USB_A (108001) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.07Å Yes No
1USB_B (108003) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.07Å Yes Yes
1XWG_B (4233496) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.85Å Yes Yes
1XWG_A (4233496) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.85Å Yes Yes
1XWG_B (122402) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.85Å Yes Yes
1XWG_B (122403) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.85Å No No
1XWG_A (122400) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.85Å Yes No
1XWG_A (122401) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.85Å No No
1YDK_B (122999) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.95Å Yes No
1YDK_B (123000) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.95Å No No
1YDK_A (4103171) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.95Å Yes Yes
1YDK_A (122998) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.95Å No No
1YDK_B (4103171) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.95Å Yes Yes
1YDK_A (122997) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.95Å No No
2R3X_B (4131890) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.8Å Yes Yes
2R3X_B (151564) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.8Å Yes No
2R3X_B (151563) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.8Å Yes No
2R3X_A (151562) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 1.8Å No No
2R3X_A (151561) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 1.8Å Yes No
2R3X_A (4131890) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.8Å Yes Yes
2R6K_A (4106341) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.51Å Yes Yes
2R6K_B (4106341) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.51Å Yes Yes
2R6K_A (151615) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.51Å No No
2R6K_A (151614) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.51Å Yes Yes
2R6K_B (151616) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain 2.51Å Yes No
2R6K_B (151617) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, Glutathione S-transferase (GST) N-terminal domain 2.51Å No No
3I69_E (4015150) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_F (4015150) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_D (4153646) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_C (4153646) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_B (4239303) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_A (4239303) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_H (4265773) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I69_G (4265773) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.3Å Yes Yes
3I6A_H (4073799) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_E (4238231) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_C (4020384) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_G (4073799) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_D (4020384) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_B (4080701) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_F (4238231) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3I6A_A (4080701) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.98Å Yes Yes
3IK9_F (4211528) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_E (4211528) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_C (4130474) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_D (4130474) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_A (4106513) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_B (4106513) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_H (4015292) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3IK9_A (3480044) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, UNMATCHED 2.1Å Yes Yes
3IK9_A (3480043) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, UNMATCHED 2.1Å No No
3IK9_G (4015292) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.1Å Yes Yes
3KTL_A (3510821) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, UNMATCHED 1.746Å No No
3KTL_B (4038031) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.746Å Yes Yes
3KTL_A (4038031) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.746Å Yes Yes
3KTL_A (3510822) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, UNMATCHED 1.746Å Yes No
3L0H_A (4138903) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.79Å Yes Yes
3L0H_B (4138903) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.79Å Yes Yes
3L0H_A (3520273) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, UNMATCHED 1.79Å Yes No
3L0H_A (3520272) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, UNMATCHED 1.79Å Yes No
3Q74_A (4176190) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.79Å Yes Yes
3Q74_B (4176190) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 1.79Å Yes Yes
3Q74_A (3680631) Glutathione S-transferase A1 Thioredoxin fold, Thioredoxin-like, UNMATCHED 1.79Å No No
3Q74_A (3680632) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, UNMATCHED 1.79Å Yes No
3U6V_A (4222228) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.19Å Yes Yes
3U6V_B (4222228) Glutathione S-transferase A1 GST C-terminal domain-like, GST C-terminal domain-like, Glutathione S-transferase (GST) C-terminal domain (Homo Multimer) 2.19Å Yes Yes
Ligand-based Druggability Score: 0.95
Ligand-based Druggability Score Percentile: 90%
Ligand-based Druggability Help: Help




		
Number of proteins in the network : 13346


GSTA1 is involved in 7 interactions in the network.


Druggability
Overall Druggability Percentile: 88.43
Druggability for Cancer Therapeutics: 69.79
Druggability for Other Therapeutics: 89.95
Cancer-Associated
Cancer-associated percentile : 43.27
Network Articulation Point
Is GSTA1 critical for communication in the network?


Detailed Graph Legend:Help