Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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glgB (P07762) - Overview - Molecular Target Synopsis

Protein


glgB, 1,4-alpha-glucan branching enzyme GlgB
Enzyme Classification 2.4.1.18
UniProt P07762

Also Known as GLGB_ECOLI, glgB

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Monomer.

4LPC
CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEPTAOSE
RCSB/PDB
Inspect Structure
See all 3D Structures for glgB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


GO terms: glgB is active in the following subcellular-locations: cytosol.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project glgB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For glgB there are:
3 structures (12 chains) solved
2 are solved in complex with at least one small molecule ligand
2 are solved with an approved drug

glgB is solved in complex with the approved drug(s):

BGC/DEXTROSE (4LPC_B, 4LPC_D, 4LQ1_A).

(see details)
Molecular Target 3D Synopsis