Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

gag (P07567) - Overview - Molecular Target Synopsis

Protein


gag, Gag polyprotein
UniProt P07567

Also Known as GAG_MPMV, gag

Matrix protein p10: Matrix protein., Nucleocapsid protein p14: Nucleocapsid protein., Capsid protein p27: capsid protein. Gag polyprotein: Interacts with host DYNLT1; this interaction probably targets the viral polyproteins to the cytoplasmic assembly site.

5LMY
SOLUTION STRUCTURE OF THE M-PMV MYRISTOYLATED MATRIX PROTEIN
RCSB/PDB
Inspect Structure
See all 3D Structures for gag

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
657P07567-1

Sub-cellular localization


UniProt: gag is active in the following subcellular-locations: virion.
GO terms: gag is active in the following subcellular-locations: host cell cytoplasm, viral nucleocapsid.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project gag has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For gag there are:
10 structures (11 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis