Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ACYP1 (P07311) - Overview - Molecular Target Synopsis

Protein


ACYP1, Acylphosphatase-1
Enzyme Classification 3.6.1.7
UniProt P07311

Also Known as ACYP1_HUMAN, ACYP1, ACYPE

Its physiological role is not yet clear.

6CBU
CRYSTAL STRUCTURE OF C4S3: A COMPUTATIONALLY DESIGNED IMMUNOGEN TO TARGET CARBOHYDRATE-OCCLUDED EPITOPES ON THE HIV ENVELOPE
RCSB/PDB
Inspect Structure
See all 3D Structures for ACYP1

Isoforms / Transcripts (Protein Coding)


Gene Copy Number Variation


In COSMIC - Cell Lines Project ACYP1 has gain in 4 cell-lines, loss in 0 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: OVCAR_5, KM12, CCRF_CEM

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: COR-L47, COR-L88, NCI-H345

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HeLa-S3, MCF-7

(see details)

3D Structures


For ACYP1 there are:
7 structures (7 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis