Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

Rbp2 (P06768) - Overview - Molecular Target Synopsis

Protein


Rbp2, Retinol-binding protein 2
UniProt P06768

Also Known as RET2_RAT, Rbp2, Crbpii

Intracellular transport of retinol.

1EII
NMR STRUCTURE OF HOLO CELLULAR RETINOL-BINDING PROTEIN II
RCSB/PDB
Inspect Structure
See all 3D Structures for Rbp2

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
134P06768-1

Sub-cellular localization


UniProt: Rbp2 is active in the following subcellular-locations: cytoplasm.
GO terms: Rbp2 is active in the following subcellular-locations: cytosol.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project Rbp2 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For Rbp2 there are:
4 structures (8 chains) solved
2 are solved in complex with at least one small molecule ligand
1 are solved with an approved drug

Rbp2 is solved in complex with the approved drug(s):

RTL/RETINOL (1EII_A).

(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


Rbp2 has been screened with compounds ( bioactivities). (see details)