Molecular Target Synopsis
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ITGAV (P06756) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), TGFB1 (P01137) HUMAN 5FFO_A 100 0 3.49Å NAG BMA MAN 2017-01-25
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 1L5G_A 100 0 3.2Å NAG NDG 2002-04-17
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4CAK_A 38.29 0 20.5Å NAG 2013-10-30
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 4WK0_A 53.64 0 1.78Å NAG BMA MAN 2014-12-03
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3NIF_A 42.74 2.0E-88 2.4Å NIF 2010-12-22
FG-GAP repeat (100%), Integrin alpha (40%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 3VI3_A 50.88 0 2.9Å NAG BMA MAN 2012-02-22
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 5HDB_C 43.01 2.0E-88 2.7Å - 2016-02-03
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4Z7Q_A 43.01 2.0E-88 2.7Å - 2015-12-16
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3T3M_A 42.74 2.0E-88 2.6Å RC2 2012-03-28
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 2VDM_A 42.98 2.0E-87 2.9Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4Z7Q_C 43.01 2.0E-88 2.7Å MAN 2015-12-16
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), (Q6PMW3), (D1H101) HUMAN 5NET_A 100 0 8.6Å NAG MAN 2017-06-21
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3NID_C 42.74 2.0E-88 2.3Å - 2010-12-22
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3NID_A 42.74 2.0E-88 2.3Å - 2010-12-22
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), TGFB3 (P10600) HUMAN 4UM9_A 100 0 2.5Å NAG BMA MAN 2014-11-12
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZE0_C 42.74 2.0E-88 2.95Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3NIF_C 42.74 2.0E-88 2.4Å NIF 2010-12-22
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZE2_A 42.74 2.0E-88 2.35Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3NIG_A 42.74 2.0E-88 2.25Å - 2010-12-22
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) FGG (P02679), ITGB3 (P05106) HUMAN 2VDP_A 42.98 2.0E-87 2.7Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 4WK4_A 53.66 0 2.5Å NAG BMA MAN 2014-12-03
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 5HDB_A 43.01 2.0E-88 2.7Å - 2016-02-03
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 4G1E_A 100 0 3Å NAG BMA MAN 2012-12-12
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) FGG (P02679), ITGB3 (P05106) HUMAN 2VDQ_A 42.98 2.0E-87 2.59Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 3IJE_A 100 0 2.9Å NAG BMA MAN 2009-09-29
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 1TYE_A 42.76 6.0E-87 2.9Å - 2004-10-12
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), (Q98W00), (Q6ZZ87), (A6Y878) HUMAN 5NER_A 100 0 11.5Å NAG MAN 2017-06-21
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 1M1X_A 100 0 3.3Å NAG NDG 2002-08-14
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZDY_A 42.74 2.0E-88 2.45Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3FCS_A 38.29 0 2.55Å NAG 2009-01-20
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 4O02_A 100 0 3.6Å NAG BMA MAN 2014-04-02
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), (Q98W00), (Q6ZZ87), (A6Y878) HUMAN 5NEM_A 100 0 10.8Å NAG MAN 2017-06-21
FG-GAP repeat (100%), Integrin alpha (40%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 3VI3_C 50.88 0 2.9Å NAG BMA MAN 2012-02-22
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 6AVU_A 100 0 35Å - 2017-11-01
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4Z7N_C 43.01 2.0E-88 2.599Å - 2015-12-16
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564) HUMAN 5FFG_A 100 0 2.25Å NAG BMA MES MAN 2017-01-25
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZE0_A 42.74 2.0E-88 2.95Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3T3M_C 42.74 2.0E-88 2.6Å RC2 2012-03-28
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZDX_A 42.74 2.0E-88 2.45Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4Z7O_C 43.01 2.0E-88 2.85Å - 2016-01-27
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 1JV2_A 100 0 3.1Å NAG NDG 2001-10-17
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564) HUMAN 4UM8_C 100 0 2.85Å NAG BMA MAN 2014-11-12
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), TGFB3 (P10600) HUMAN 4UM9_C 100 0 2.5Å NAG BMA MAN 2014-11-12
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 6AVQ_A 100 0 35Å - 2017-11-01
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3FCU_C 42.74 2.0E-88 2.9Å NAG 2009-01-20
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 2VC2_A 42.98 2.0E-87 3.1Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 2VDN_A 42.98 2.0E-87 2.9Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 6AVR_A 100 0 35Å - 2017-11-01
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), (Q6PMW3), (D1H101) HUMAN 5NEU_A 100 0 12.3Å - 2017-06-21
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3NIG_C 42.74 2.0E-88 2.25Å - 2010-12-22
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB8 (P26012) HUMAN 6DJP_A 100 0 4.8Å NAG BMA MAN 2018-07-25
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564) HUMAN 4UM8_A 100 0 2.85Å NAG BMA MAN 2014-11-12
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZDZ_C 42.74 2.0E-88 2.75Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106), FN1 (P02751) HUMAN 4MMY_A 100 0 3.18Å NAG BMA MAN 2014-03-26
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) FGG (P02679), ITGB3 (P05106) HUMAN 2VDO_A 42.98 2.0E-87 2.51Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 1TYE_C 42.76 6.0E-87 2.9Å - 2004-10-12
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZE2_C 42.74 2.0E-88 2.35Å NAG 2013-06-05
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 1TYE_E 42.76 6.0E-87 2.9Å NAG 2004-10-12
FG-GAP repeat (100%), Integrin alpha (40%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 3VI4_C 50.88 0 2.9Å NAG BMA MAN 2012-02-22
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZDZ_A 42.74 2.0E-88 2.75Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 2VDL_A 42.98 2.0E-87 2.75Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZE1_A 42.74 2.0E-88 3Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (36%) (view alignment) ITGAV (P06756) ITGB6 (P18564), TGFB1 (P01137) HUMAN 5FFO_E 100 0 3.49Å NAG BMA MAN 2017-01-25
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106), FN1 (P02751) HUMAN 4MMX_A 100 0 3.32Å NAG BMA MAN 2014-03-26
FG-GAP repeat (100%), Integrin alpha (40%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 3VI4_A 50.88 0 2.9Å NAG BMA MAN 2012-02-22
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZE1_C 42.74 2.0E-88 3Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) FGG (P02679), ITGB3 (P05106) HUMAN 2VDR_A 42.98 2.0E-87 2.4Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 4G1M_A 100 0 2.9Å NAG BMA MAN 2012-12-12
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3FCU_A 42.74 2.0E-88 2.9Å NAG 2009-01-20
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4Z7N_A 43.01 2.0E-88 2.599Å - 2015-12-16
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 4Z7O_A 43.01 2.0E-88 2.85Å - 2016-01-27
FG-GAP repeat (100%), Integrin alpha (1%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 2VDK_A 42.98 2.0E-87 2.8Å NAG 2008-09-02
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3FCU_E 42.74 2.0E-88 2.9Å NAG 2009-01-20
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 4WJK_A 53.64 0 1.85Å NAG BMA MAN 2014-12-03
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA5 (P08648) ITGB1 (P05556) HUMAN 4WK2_A 53.64 0 2.5Å NAG BMA MAN 2014-12-03
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3T3P_A 42.74 2.0E-88 2.2Å - 2012-03-28
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3T3P_C 42.74 2.0E-88 2.2Å - 2012-03-28
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3FCS_C 38.29 0 2.55Å NAG 2009-01-20
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZDY_C 42.74 2.0E-88 2.45Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (2%) (view alignment) ITGA2B (P08514) ITGB3 (P05106) HUMAN 3ZDX_C 42.74 2.0E-88 2.45Å - 2013-06-05
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106) HUMAN 1U8C_A 100 0 3.1Å NAG NDG 2004-12-28
FG-GAP repeat (100%), Integrin alpha (100%) (view alignment) ITGAV (P06756) ITGB3 (P05106), FN1 (P02751) HUMAN 4MMZ_A 100 0 3.1Å NAG BMA MAN 2014-03-26