Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
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Ligand Efficiency Plot
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ASL (P04424) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJW_C 71.62 0 2Å AS1 2004-09-07
Lyase (98%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1DCN_B 71.53 0 2.3Å - 1999-04-27
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P11447) - 1TJ7_B 45.82 7.0E-103 2.44Å - 2004-10-26
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_G 43.23 6.0E-89 2.2Å - 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJW_B 71.62 0 2Å AS1 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1U15_B 71.93 0 2.5Å - 2004-10-05
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P04424) - HUMAN 1AOS_B 100 0 4Å - 1998-01-14
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1HY1_C 71.83 0 2.3Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P04424) - HUMAN 1K62_A 100 0 2.65Å - 2002-02-01
Lyase (98%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1DCN_D 71.53 0 2.3Å AS1 1999-04-27
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1U16_A 71.93 0 2.2Å MES 2004-10-05
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1AUW_A 71.62 0 2.5Å - 1998-03-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (Q7SIE0) - TURKEY 1I0A_B 65.79 0 2.5Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1K7W_A 71.83 0 1.96Å AS1 2002-03-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (Q7SIE0) - TURKEY 1I0A_D 65.79 0 2.5Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1U15_A 71.93 0 2.5Å - 2004-10-05
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1HY0_A 69.74 0 2.2Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1HY0_B 69.74 0 2.2Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IGA_C 43.23 6.0E-89 2.776Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJW_D 71.62 0 2Å AS1 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1K7W_C 71.83 0 1.96Å AS1 2002-03-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJU_C 71.62 0 2.1Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IG5_B 43.23 6.0E-89 2.078Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1U15_C 71.93 0 2.5Å - 2004-10-05
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_C 43.23 6.0E-89 2.2Å - 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P11447) - 1TJ7_A 45.82 7.0E-103 2.44Å - 2004-10-26
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_A 43.23 6.0E-89 2.2Å - 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IG5_A 43.23 6.0E-89 2.078Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (P24057) - 1U15_D 71.93 0 2.5Å - 2004-10-05
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJU_D 71.62 0 2.1Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_E 43.23 6.0E-89 2.2Å 2PE 2019-02-20
Lyase (98%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1DCN_C 71.53 0 2.3Å - 1999-04-27
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IGA_B 43.23 6.0E-89 2.776Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJW_A 71.62 0 2Å AS1 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEN_B 43.23 6.0E-89 2.7Å AS1 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IGA_D 43.23 6.0E-89 2.776Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_F 43.23 6.0E-89 2.2Å PGE 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJU_A 71.62 0 2.1Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEN_A 43.23 6.0E-89 2.7Å FUM AS1 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJU_B 71.62 0 2.1Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEN_C 43.23 6.0E-89 2.7Å ARG 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (Q5SLL0) - 2E9F_C 45.92 5.0E-106 2.8Å - 2007-07-31
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P04424) - HUMAN 1AOS_A 100 0 4Å - 1998-01-14
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEN_D 43.23 6.0E-89 2.7Å AS1 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1K7W_D 71.83 0 1.96Å AS1 2002-03-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1AUW_B 71.62 0 2.5Å - 1998-03-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P33110) - WESTERN GRAYLAG GOOSE 1XWO_A 69.45 0 2.8Å - 2005-10-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (Q7SIE0) - TURKEY 1I0A_A 65.79 0 2.5Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJV_A 71.62 0 2Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (Q5SLL0) - 2E9F_D 45.92 5.0E-106 2.8Å - 2007-07-31
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IG5_C 43.23 6.0E-89 2.078Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IG5_D 43.23 6.0E-89 2.078Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_H 43.23 6.0E-89 2.2Å - 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1K7W_B 71.83 0 1.96Å AS1 2002-03-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJV_B 71.62 0 2Å - 2004-09-07
Lyase (98%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1DCN_A 71.53 0 2.3Å - 1999-04-27
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1HY1_A 71.83 0 2.3Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_B 43.23 6.0E-89 2.2Å - 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1HY1_D 71.83 0 2.3Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJV_D 71.62 0 2Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1TJV_C 71.62 0 2Å - 2004-09-07
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IGA_A 43.23 6.0E-89 2.776Å - 2019-02-06
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (P9WPY7) - 6IEM_D 43.23 6.0E-89 2.2Å P3G 2019-02-20
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (Q5SLL0) - 2E9F_A 45.92 5.0E-106 2.8Å - 2007-07-31
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1HY1_B 71.83 0 2.3Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL1 (Q7SIE0) - TURKEY 1I0A_C 65.79 0 2.5Å - 2001-04-21
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P04424) - HUMAN 1K62_B 100 0 2.65Å - 2002-02-01
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1AUW_C 71.62 0 2.5Å - 1998-03-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P33110) - WESTERN GRAYLAG GOOSE 1XWO_C 69.45 0 2.8Å - 2005-10-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) argH (Q5SLL0) - 2E9F_B 45.92 5.0E-106 2.8Å ARG 2007-07-31
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P33110) - WESTERN GRAYLAG GOOSE 1XWO_B 69.45 0 2.8Å - 2005-10-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL (P33110) - WESTERN GRAYLAG GOOSE 1XWO_D 69.45 0 2.8Å - 2005-10-18
Lyase (100%), Argininosuccinate lyase C-terminal (100%) (view alignment) ASL2 (P24058) - 1AUW_D 71.62 0 2.5Å - 1998-03-18