Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pilA (P02973) - Overview - Molecular Target Synopsis

Protein


pilA, Fimbrial protein
UniProt P02973

Also Known as FMPA_PSEAI, pilA, fimA

The pili are polar flexible filaments of about 5.4 nanometers diameter and 2.5 micrometers average length; they consist of only a single polypeptide chain arranged in a helical configuration of five subunits per turn in the assembled pilus.

5VXY
CRYO-EM RECONSTRUCTION OF PAK PILUS FROM PSEUDOMONAS AERUGINOSA
RCSB/PDB
Inspect Structure
See all 3D Structures for pilA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
150P02973-1

Sub-cellular localization


UniProt: pilA is active in the following subcellular-locations: fimbrium.
GO terms: pilA is active in the following subcellular-locations: pilus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project pilA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pilA there are:
14 structures (35 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis