Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

bop (P02945) - Overview - Molecular Target Synopsis

Protein


bop, Bacteriorhodopsin
UniProt P02945

Also Known as BACR_HALSA, bop

Light-driven proton pump. Homotrimer.

6RMK
BACTERIORHODOPSIN, DARK STATE, CELL 2, REFINED USING THE SAME PROTOCOL AS SUB-PS TIME DELAYS
RCSB/PDB
Inspect Structure
See all 3D Structures for bop

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
262P02945-1

Sub-cellular localization


UniProt: bop is active in the following subcellular-locations: cell membrane.
GO terms: bop is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project bop has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For bop there are:
149 structures (177 chains) solved
145 are solved in complex with at least one small molecule ligand
2 are solved with an approved drug

bop is solved in complex with the approved drug(s):

BGC/DEXTROSE (1BRR_B, 1KME_B).

(see details)
Molecular Target 3D Synopsis