Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

argT (P02911) - Overview - Molecular Target Synopsis

Protein


argT, Lysine/arginine/ornithine-binding periplasmic protein
UniProt P02911

Also Known as ARGT_SALTY, argT

Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP. The complex is composed of two ATP-binding proteins (HisP), two transmembrane proteins (HisM and HisQ) and a solute-binding protein (ArgT).

6FT2
STRUCTURE OF THE PERIPLASMIC BINDING PROTEIN LAO-Q122A IN COMPLEX WITH ARGININE.
RCSB/PDB
Inspect Structure
See all 3D Structures for argT

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
260P02911-1

Sub-cellular localization


UniProt: argT is active in the following subcellular-locations: periplasm.
GO terms: argT is active in the following subcellular-locations: outer membrane-bounded periplasmic space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project argT has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For argT there are:
7 structures (7 chains) solved
6 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis