Molecular Target Synopsis
Overview
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Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
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Germline Genetics

FGG (P02679) - Pathways - Molecular Target Synopsis

Data acquired from 17 pathway associations found
Pathway Name Source
Common Pathway of Fibrin Clot FormationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
GRB2:SOS provides linkage to MAPK signaling for IntegrinsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Integrin alphaIIb beta3 signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Integrin cell surface interactionsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
MAP2K and MAPK activationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
p130Cas linkage to MAPK signaling for integrinsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Paradoxical activation of RAF signaling by kinase inactive BRAFReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Platelet degranulationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Post-translational protein phosphorylationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Regulation of IGF Activity by IGFBPReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Regulation of TLR by endogenous ligandReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Signaling by BRAF and RAF fusionsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Signaling by high-kinase activity BRAF mutantsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Signaling by moderate kinase activity BRAF mutantsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Signaling by RAS mutantsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Blood coagulationPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Plasminogen activating cascadePANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)