Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(P02077) - Overview - Molecular Target Synopsis

Protein


, Hemoglobin subunit beta-A
UniProt P02077

Also Known as HBBA_CAPHI

Involved in oxygen transport from the lung to the various peripheral tissues. Heterotetramer of two alpha chains and two beta chains.

3EU1
CRYSTAL STRUCTURE DETERMINATION OF GOAT HEMOGLOBIN (CAPRA HIRCUS) AT 3 ANGSTROM RESOLUTION
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
145P02077-1

Sub-cellular localization


GO terms: is active in the following subcellular-locations: hemoglobin complex.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
3 structures (8 chains) solved
3 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


has been screened with compounds ( bioactivities). (see details)