Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

H2-D1 (P01899) - Overview - Molecular Target Synopsis

Protein


H2-D1, H-2 class I histocompatibility antigen, D-B alpha chain
UniProt P01899

Also Known as HA11_MOUSE, H2-D1

Involved in the presentation of foreign antigens to the immune system. Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with murid herpesvirus 4 protein K3 (mK3).

6G9R
MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2 DB IN COMPLEX WITH SELF-ANTIGEN DERIVED FROM DOPAMINE MONOOXYGENASE.
RCSB/PDB
Inspect Structure
See all 3D Structures for H2-D1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
362P01899-1

Sub-cellular localization


Gene Copy Number Variation


In COSMIC - Cell Lines Project H2-D1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For H2-D1 there are:
78 structures (177 chains) solved
3 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


H2-D1 has been screened with compounds ( bioactivities). (see details)