Molecular Target Synopsis
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KRAS (P01116) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 08/10/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 08/10/2019)


Chains assessed307
Chains with at least one site assessed as druggable using the strict criteria132
Chains with at least one site assessed as druggable using the relaxed criteria271


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
6GOM_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.48 70.1 36.1 Yes Yes
2 empty 2.32 62.6 20.4 No No
3 empty 2.32 68 17.7 No No
4 empty 2.29 48.4 15 No No
5 empty 2.16 72.7 10.5 No No
6 empty 2.11 69 7.1 No No
7 empty 2.54 57.8 14.6 No No
8 empty 1.96 66.3 11.3 No No
9 empty 2.2 61.4 7.8 No No
10 empty 2.61 57.5 6.8 No No
6P8W_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.47 79.9 30.1 Yes Yes
2 empty 2.31 64.8 24.3 No No
3 empty 2.38 62 17.3 No No
4 empty 2.14 65.6 9.2 No No
5 empty 1.95 56.8 11.4 No No
6 empty 2.33 65 7.4 No No
7 empty 2.13 63.8 7.5 No No
8 empty 2.85 68.8 8.3 No No
9 empty 2.57 61.7 8.4 No No
10 empty 3.02 51.2 10.4 No No
4Q03_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 63 31.3 Yes No
2 bound 2.17 77.7 15.7 No No
3 empty 2.18 62.9 17.5 No No
4 empty 2.74 56.6 11.9 No No
5 empty 2.04 53.7 10.3 No No
6 empty 2.02 59.7 8.7 No No
7 empty 2.17 56.3 9.9 No No
8 empty 2.12 56.1 9.2 No No
9 empty 2.95 58.8 10.6 No No
10 empty 1.71 58.2 7.9 No No
4PZY_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 70.1 25.7 Yes No
2 empty 2.45 67.7 19.2 No No
3 bound 2.29 68.1 19.2 No No
4 empty 2.38 63 17.5 No No
5 empty 1.91 72.8 8.1 No No
6 empty 2.26 66.9 11.1 No No
7 empty 2.12 58.1 8.8 No No
8 empty 2.84 64.7 7.2 No No
9 empty 2.6 50.8 10 No No
10 empty 2.13 56.8 8.5 No No
5TB5_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 40.6 14.2 No No
2 empty 2.22 67.2 21.9 No No
3 empty 2.1 66.7 17.4 No No
4 empty 2.13 75.2 11.7 No No
5 empty 2.33 61.6 17.6 No No
6 empty 2.17 48.2 14.9 No No
7 empty 2.35 70.8 9.2 No No
8 empty 2.51 68.1 8.5 No No
9 bound 1.67 71 9.5 No No
10 empty 2.16 68.8 8 No No
4OBE_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 70.4 39.9 Yes Yes
2 empty 2.67 69.2 17.1 No No
3 empty 2.22 66.5 17.6 No No
4 empty 1.94 72.2 6.4 No No
5 empty 2.87 63 8.8 No No
6 empty 2.28 59.9 7.7 No No
7 empty 3.12 55.6 6.7 No No
8 empty 2.36 58 6.6 No No
9 empty 2.29 68.3 5.3 No No
10 empty 2.63 57.5 6.1 No No
6OB3_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.54 77.2 22 Yes No
2 empty 2.2 71.2 11.5 No No
3 empty 1.95 65.3 13.7 No No
4 empty 2.45 70.5 10.8 No No
5 empty 2.21 73.1 9.5 No No
6 empty 2.23 72.8 6.6 No No
7 empty 2.24 59.6 9.6 No No
8 empty 3.04 71.9 6.4 No No
9 empty 2.43 56.5 9.3 No No
10 empty 3.08 64.6 5.6 No No
6BOF_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.55 61.6 27.2 Yes No
2 empty 2.37 57.5 30.6 No No
3 empty 2.58 64.1 27.7 No No
4 empty 2.61 62.1 10.2 No No
5 empty 2.28 76.2 9.8 No No
6 empty 1.82 61.5 11.3 No No
7 bound 1.9 70.7 7.5 No No
8 empty 2.83 67.5 5.8 No No
9 empty 1.83 61.7 8.2 No No
10 empty 2.7 72.9 7.5 No No
6F76_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.44 72.8 26.3 Yes No
2 empty 2.18 55 26.7 No No
3 bound 2.22 70.4 22 No No
4 empty 2.53 62.6 20.7 No No
5 empty 2.01 73.4 9.2 No No
6 empty 2.12 65.3 9.8 No No
7 empty 1.11 66.1 6.7 No No
8 empty 2.81 58.6 7.9 No No
9 empty 2.35 65.4 7.6 No No
10 empty 2.91 52.6 6.8 No No
4M1Y_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.3 63.6 14.3 No No
2 empty 2.48 66.2 15.7 No No
3 bound 1.87 73.5 12.9 No No
4 empty 1.89 66.2 13.8 No No
5 empty 2.03 69.1 10.2 No No
6 empty 2.51 67.1 7.2 No No
7 empty 2.24 67.9 9.1 No No
8 empty 2.3 58.4 9 No No
9 empty 2.97 68.5 7.3 No No
10 empty 2.59 53.7 7.6 No No
5V9U_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 80.5 30.3 Yes Yes
2 empty 2.27 61 15.3 No No
3 empty 2.19 64 15.2 No No
4 empty 2.4 63.7 12.8 No No
5 empty 1.63 55.2 10.7 No No
6 empty 2.04 60.7 8.9 No No
7 empty 2.16 64.1 7 No No
8 empty 1.96 59.9 9.4 No No
9 empty 2.57 58 7.7 No No
10 empty 2.84 60 9.3 No No
4LYF_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 75.9 22.3 Yes Yes
2 empty 2.45 68.7 12.9 No No
3 bound 1.84 72.9 13.1 No No
4 empty 2.46 63 9.5 No No
5 empty 1.97 62.6 10.2 No No
6 empty 2.04 73.4 7.7 No No
7 empty 2.87 56.2 10.2 No No
8 empty 2.7 62.2 7.2 No No
9 empty 2.37 54.3 9.7 No No
10 empty 2.29 57 8.7 No No
6FA3_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 69.7 37.5 Yes Yes
2 empty 2.39 61.8 19.5 No No
3 empty 2.29 49.4 18.8 No No
4 bound 2.13 71.9 13.2 No No
5 empty 2.32 65.2 13.4 No No
6 empty 2.83 61.1 11.7 No No
7 empty 2.13 61 9.5 No No
8 empty 1.92 72 9.7 No No
9 empty 2.78 62.2 9.5 No No
10 empty 2.82 69.6 6.3 No No
6FA2_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.57 82.2 20.5 Yes Yes
2 empty 2.54 69 23.6 No No
3 empty 2.24 52.3 20.4 No No
4 empty 2.68 66.9 18 No No
5 bound 2.23 72.1 13.5 No No
6 empty 2.54 71.3 8.5 No No
7 empty 1.98 69.7 7.8 No No
8 empty 2.32 54.3 9.8 No No
9 empty 1.91 66.2 6.3 No No
10 empty 2.24 61.3 6 No No
6GQY_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 71.1 28.5 Yes No
2 empty 2.33 72.1 18.5 No No
3 empty 2.32 55.4 19.7 No No
4 empty 2.62 67.6 18.6 No No
5 empty 2.08 72.9 5.8 No No
6 empty 2.18 69.2 8.5 No No
7 empty 2.19 59.4 10 No No
8 empty 2.5 65.2 6.8 No No
9 empty 2.24 62.9 6.3 No No
10 empty 2.48 52.4 9.8 No No
5VQ2_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.27 66 31.7 Yes No
2 empty 2.16 65.4 11.9 No No
3 empty 2.28 57.2 15.7 No No
4 empty 2.56 74.6 15.6 No No
5 empty 2.49 58 21.2 No No
6 empty 2.46 61.3 10.8 No No
7 empty 2.12 72 7.3 No No
8 empty 1.81 74.6 7 No No
9 empty 3.01 66.4 6.8 No No
10 empty 2.01 65.9 9 No No
6GOF_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 77 23.9 Yes No
2 empty 2.69 66.1 24.6 No No
3 empty 2.6 69.2 16 No No
4 empty 2.07 52.3 17.4 No No
5 empty 2.08 70.9 12.7 No No
6 empty 1.96 69.1 14.9 No No
7 empty 2.28 65.7 8.5 No No
8 empty 2.02 66.3 7 No No
9 empty 2.77 64.2 8.3 No No
10 empty 2.53 66.7 5.4 No No
3GFT_F GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 67.5 20.8 No No
2 empty 2.22 54.5 19.6 No No
3 empty 2.59 63.5 21.4 No No
4 empty 1.92 70.4 8.6 No No
5 empty 2.15 68.8 10.1 No No
6 empty 2.19 55.5 6.9 No No
7 empty 1.88 73.3 8.7 No No
8 empty 2.47 64.8 7.3 No No
9 empty 1.94 74.2 5.8 No No
10 empty 2.78 60.8 5.7 No No
4LUC_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 78.4 34.6 Yes Yes
2 empty 2.28 62.3 20.7 No No
3 empty 2.37 72 14.4 No No
4 empty 2.67 68.5 11.4 No No
5 empty 2.16 67.8 7.9 No No
6 empty 2.18 66.1 7.3 No No
7 empty 2.22 67.6 6.9 No No
8 empty 2.04 72.3 6.9 No No
9 empty 2.82 67.7 8.2 No No
10 empty 2.25 61.8 4.7 No No
4WA7_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 76.3 21 Yes No
2 empty 2.59 63.6 23.3 No No
3 empty 2.35 64.8 14.5 No No
4 empty 2.03 61.5 16 No No
5 empty 2.24 72.8 13.7 No No
6 empty 2.13 56.6 10.4 No No
7 empty 2.57 73 8.1 No No
8 empty 2.03 60.3 7.8 No No
9 empty 2.22 62.9 9.2 No No
10 empty 2.63 67.8 7.1 No No
4LYH_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 71.7 21.9 Yes No
2 empty 2.6 67.3 17.9 No No
3 bound 2.51 73.1 10.4 No No
4 empty 1.84 68.8 10.5 No No
5 empty 2.58 53.3 11 No No
6 empty 2.22 68.6 8.1 No No
7 empty 2.11 69.5 7.9 No No
8 empty 2.29 65.5 9.6 No No
9 empty 2.06 64.2 7.2 No No
10 empty 2.45 58.4 9.3 No No
5V6V_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 78.6 35.6 Yes Yes
2 empty 2.51 63.2 27.2 No No
3 empty 2.06 54.6 15.1 No No
4 empty 2.08 68.7 8.8 No No
5 empty 2.19 68.3 7.9 No No
6 empty 2.07 61.2 8.2 No No
7 empty 2.9 68.4 6.6 No No
8 empty 2.82 70.1 5.5 No No
9 empty 2.96 65.4 6.7 No No
10 empty 2.23 64.7 7.6 No No
4LPK_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 73.4 19.6 Yes No
2 empty 2.2 66.3 13.7 No No
3 empty 2.73 72.9 14.3 No No
4 empty 2.44 70.1 13.4 No No
5 empty 2.28 64 12 No No
6 empty 2.42 64.8 14.1 No No
7 empty 2.58 58.6 10.2 No No
8 empty 1.98 66.2 9.9 No No
9 empty 2.68 62.9 6.4 No No
10 empty 2.33 57 7.5 No No
6FA1_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.52 68.4 32.8 Yes Yes
2 empty 2.32 61.4 18.7 No No
3 empty 2.63 68.3 17.8 No No
4 empty 2.31 49.6 16.3 No No
5 bound 1.9 76.2 11 No No
6 empty 1.97 73.4 7 No No
7 empty 2.45 56.7 8.8 No No
8 empty 2.88 66.9 6.3 No No
9 empty 2.92 78.1 0 No No
10 empty 2.64 58.8 6.4 No No
5W22_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.47 70.4 40.3 Yes Yes
2 empty 2.68 64.4 16.4 No No
3 empty 1.94 66.8 13 No No
4 empty 2.26 55.7 12.9 No No
5 empty 1.74 64 12.2 No No
6 empty 2.38 54.9 12.3 No No
7 empty 2.38 70.5 10.4 No No
8 empty 2.81 56.6 9.8 No No
9 empty 2.5 51.2 12.3 No No
10 empty 2.49 52.3 7 No No
6EPN_R GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 68.4 20.8 No No
2 empty 2.28 63.3 24.9 No No
3 bound 2.48 65.3 20.8 No No
4 empty 1.97 64.3 20 No No
5 empty 2.17 61.1 16.4 No No
6 empty 2.3 69.7 19.2 No No
7 empty 2.4 58.6 12.8 No No
8 empty 2.33 58.6 13 No No
9 empty 2 99.6 0 Yes No
10 empty 2.21 69.1 7.1 No No
6E6G_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 71.2 25 Yes No
2 empty 2.24 62.2 12.6 No No
3 empty 2.24 69.9 15.9 No No
4 empty 2.34 67.4 9.5 No No
5 empty 2.7 67.7 9.8 No No
6 empty 2.5 65.3 9 No No
7 empty 1.84 65.3 9.8 No No
8 empty 2.16 58.9 11 No No
9 empty 2.58 69.4 5.8 No No
10 empty 2.08 68.6 7.9 No No
6GQW_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 73.2 34.6 Yes No
2 empty 2.66 64.9 22.8 No No
3 bound 2.29 65.1 22.4 No No
4 empty 2.65 50.8 19.6 No No
5 empty 2.08 70.1 9.3 No No
6 empty 1.63 66.7 9.7 No No
7 empty 2.28 61.9 6.6 No No
8 empty 2.51 51.8 9.9 No No
9 empty 2.63 65.8 6.8 No No
10 empty 2.08 62.2 5.8 No No
5OCG_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 72.7 27.5 Yes No
2 empty 2.24 65.4 22 No No
3 bound 2.3 65.1 25.3 No No
4 bound 2 77.5 13.6 No No
5 empty 2.08 56.7 16 No No
6 empty 2.05 65.5 15.3 No No
7 empty 2.82 61.2 7.3 No No
8 bound 1.94 60.2 7.6 No No
9 empty 2.32 64.3 5.3 No No
10 empty 2.93 56.3 7 No No
5WHA_J GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.32 70.4 31.9 Yes Yes
2 empty 2.14 62 18.4 No No
3 empty 2.51 64.2 15.9 No No
4 bound 2.11 69.2 8.3 No No
5 empty 2.5 64.8 10.2 No No
6 bound 1.35 73.4 7.9 No No
7 empty 2.48 74 8.5 No No
8 empty 2.69 71.5 6.8 No No
9 empty 2.85 66 6.6 No No
10 empty 3.1 65 6.2 No No
5VP7_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 71.7 30.8 Yes Yes
2 empty 2.58 70.4 19.2 No No
3 empty 2.57 72.3 10.1 No No
4 empty 1.81 66.7 10.7 No No
5 empty 2.42 57.8 18.8 No No
6 empty 2.32 61.2 10.4 No No
7 empty 2.39 56.1 10.6 No No
8 empty 1.8 70.8 6.9 No No
9 empty 3.26 57.7 9.9 No No
10 empty 2.74 56.3 8.2 No No
5OCO_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.5 70.6 30.8 Yes No
2 empty 2.28 54.3 18.3 No No
3 empty 2.28 68.1 17.6 No No
4 empty 2.34 64.2 15.1 No No
5 bound 2.01 72.5 12.2 No No
6 empty 1.96 71.9 6.6 No No
7 empty 2.1 69.8 6.2 No No
8 empty 2.52 54.5 8.1 No No
9 empty 2.98 62.9 5.6 No No
10 empty 1.95 58.9 7.8 No No
6CU6_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 75.8 24.6 Yes No
2 empty 1.98 73.2 15.9 No No
3 empty 2.16 67.7 18.7 No No
4 empty 1.97 64.1 14.7 No No
5 empty 2.17 61.3 12.8 No No
6 empty 2.22 60.3 10.4 No No
7 empty 2.12 70.6 7.6 No No
8 empty 2.77 64.3 8.8 No No
9 empty 2.04 61.5 8.3 No No
10 empty 2.4 56 9 No No
5O2S_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 61.3 32 Yes No
2 bound 1.94 76.2 19.6 No No
3 empty 2.28 63.7 17.5 No No
4 empty 2.39 61.8 10.8 No No
5 empty 2.6 57.2 12.2 No No
6 empty 2 61.8 8.5 No No
7 empty 2.74 61.4 10.2 No No
8 empty 2.04 70.5 6.1 No No
9 empty 2.61 62.1 7.1 No No
10 empty 2.6 66 8.8 No No
6ASE_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 70.6 23.9 Yes Yes
2 empty 1.99 69.2 21.3 No No
3 empty 2.54 69.9 19.7 No No
4 empty 2.27 62.9 15.7 No No
5 empty 2.37 69.4 14.1 No No
6 empty 2.27 61.1 16.8 No No
7 empty 2.25 67.7 10.4 No No
8 empty 2.16 69.8 7.6 No No
9 empty 2.49 75.7 4.5 No No
10 empty 2.85 56.7 13 No No
4M1S_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 65.7 21.6 No No
2 empty 2.39 66.9 17 No No
3 empty 2.1 69.8 12.3 No No
4 empty 1.95 62.5 14.6 No No
5 empty 1.69 68.4 11.6 No No
6 empty 2.37 81.1 11.2 No No
7 empty 2.06 63.9 10.6 No No
8 empty 2.01 73.2 9 No No
9 empty 2.54 64.8 6.1 No No
10 empty 1.43 66.9 7 No No
6GQT_D GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 69.8 20.7 No No
2 empty 2.67 64.2 26.4 No No
3 empty 2.27 52.4 18.5 No No
4 bound 2.08 69.5 10.8 No No
5 empty 2.31 68.6 10.6 No No
6 empty 2.04 65.8 10.4 No No
7 empty 2.05 60.1 11.4 No No
8 empty 2.91 63.2 9.2 No No
9 empty 2.14 55 8.7 No No
10 empty 1.72 73.7 6.9 No No
4EPW_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 62.3 24.8 Yes No
2 bound 2.14 74 17.8 No No
3 empty 2.3 63.2 18 No No
4 empty 2.32 66.3 13.3 No No
5 empty 2.61 56.5 16.6 No No
6 empty 2.13 55.6 15.7 No No
7 empty 1.87 64.3 7.2 No No
8 empty 2.89 58.9 9.4 No No
9 empty 1.73 74.8 7.2 No No
10 empty 2.06 49.3 10.4 No No
3GFT_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 70 25.9 Yes No
2 empty 1.99 70.2 18.2 No No
3 empty 2.57 53.8 21.2 No No
4 empty 2.16 63.2 16.8 No No
5 empty 2.06 55.2 9.8 No No
6 empty 2.2 69.9 8.2 No No
7 empty 1.87 61.7 8.5 No No
8 empty 2.58 62.7 8.1 No No
9 empty 2.45 59.9 7.5 No No
10 empty 2.47 63.6 7 No No
6FA2_F GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 64.1 25.5 Yes No
2 empty 2.59 64.6 19.4 No No
3 empty 2.47 54.2 14.3 No No
4 bound 2.21 73.9 13.3 No No
5 empty 2 69.1 12 No No
6 empty 2 52.7 11 No No
7 empty 2.38 60.3 13.7 No No
8 empty 1.95 73.4 7 No No
9 empty 2.07 66.7 8.6 No No
10 empty 1.84 54.6 8.1 No No
4M1O_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 72.8 29.3 Yes Yes
2 empty 2.42 71.1 14 No No
3 bound 1.83 74.4 12.8 No No
4 empty 2.55 55.6 19.5 No No
5 empty 2.23 63.4 15.6 No No
6 empty 2.05 68.8 6.8 No No
7 empty 2.29 57.1 9.5 No No
8 empty 1.87 66.9 7.4 No No
9 empty 2.44 62 6.9 No No
10 empty 2.35 57.3 6.2 No No
6GQX_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 73 32.6 Yes No
2 empty 2.09 67.5 20.8 No No
3 empty 2.69 65 25.7 No No
4 empty 2.53 50.4 19.5 No No
5 bound 2.23 63.6 23.7 No No
6 empty 2.32 75.7 6.7 No No
7 empty 2.28 58.4 7.8 No No
8 empty 2.71 60.2 7 No No
9 empty 2.3 62 5.5 No No
10 empty 1.61 67.7 5.6 No No
6MQG_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.31 63.4 23.6 No No
2 bound 2.12 62.5 22 No No
3 empty 2.44 69.9 18 No No
4 empty 2.22 58.8 24.7 No No
5 bound 2.02 67 15.2 No No
6 empty 2.53 58.3 11.2 No No
7 empty 2.28 74.4 9.9 No No
8 empty 2.08 66.7 8.2 No No
9 empty 2.52 57.7 10 No No
10 empty 2.71 53.2 11.7 No No
5OCO_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 82.5 19.7 Yes Yes
2 empty 2.23 64.6 16.9 No No
3 empty 2.46 47.4 18.6 No No
4 empty 2.38 71.9 9.3 No No
5 empty 2.31 55.8 13.1 No No
6 empty 2.13 58.9 11.3 No No
7 empty 1.75 63 10.2 No No
8 empty 1.41 52.8 8.9 No No
9 empty 2 58.4 8.4 No No
10 bound 2.2 67.5 8.9 No No
6B0V_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 78.9 30.8 Yes Yes
2 empty 2.36 66.8 13.6 No No
3 empty 2.28 62.8 18.3 No No
4 empty 2.47 58.1 12.3 No No
5 empty 2.69 59.8 8.4 No No
6 empty 2.33 61.5 10.9 No No
7 empty 2.11 60.9 8.6 No No
8 empty 2.58 68.5 9.4 No No
9 empty 2.4 64.5 8.8 No No
10 empty 2.94 65.4 5.9 No No
4M1T_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 71.8 35.6 Yes Yes
2 empty 2.36 66.2 17.2 No No
3 empty 2.32 71.8 7.9 No No
4 empty 2.34 61.7 7.9 No No
5 empty 2.56 70.1 8.7 No No
6 empty 2.34 56.8 8.4 No No
7 empty 2.31 61.8 5.5 No No
8 empty 1.06 61.6 7.8 No No
9 empty 3.33 65.3 6.7 No No
10 empty 2.4 66.1 7.1 No No
5OCT_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 72.4 31.6 Yes No
2 empty 2.56 63.1 19.2 No No
3 empty 2.23 51.9 15.3 No No
4 empty 2.22 60.9 14.3 No No
5 bound 1.96 77.6 10.3 No No
6 empty 2.22 57.4 9.6 No No
7 empty 2.81 63.8 10.5 No No
8 empty 2.02 71.2 6.9 No No
9 empty 2.41 55.1 9.2 No No
10 empty 2.99 64.2 9.5 No No
4M22_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 81.8 15.5 Yes Yes
2 empty 2.14 65.7 16.9 No No
3 empty 2.17 71.5 10.9 No No
4 empty 2.14 78.4 10.7 No No
5 empty 1.97 70 7.8 No No
6 empty 2.17 63.6 8.6 No No
7 empty 2.53 62 13.6 No No
8 empty 1.79 54.5 13 No No
9 empty 2.17 59.8 7.3 No No
10 empty 1.7 66 6.8 No No
5OCT_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.42 73.5 23.9 Yes Yes
2 empty 2.26 53.5 19 No No
3 empty 2.28 64.9 17.7 No No
4 bound 1.89 72.5 14.8 No No
5 empty 2.26 66.2 12.2 No No
6 bound 2.44 58.2 16.3 No No
7 empty 2.39 61.5 10.2 No No
8 empty 2.09 75 6.4 No No
9 bound 2.5 67.3 7.8 No No
10 empty 2.5 72 5.4 No No
4M21_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.57 65.5 19.8 No No
2 bound 1.81 69.9 15.5 No No
3 empty 2.04 67.5 10.6 No No
4 bound 1.63 73 10.3 No No
5 empty 2.01 70.8 7.9 No No
6 empty 1.99 57.5 8.2 No No
7 empty 2.38 54.6 8.6 No No
8 empty 2.25 69.5 7.9 No No
9 empty 1.02 75 5.6 No No
10 empty 1.7 62.7 6.9 No No
6GQX_E GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 64.9 20.4 No No
2 empty 2.27 69.2 20.2 No No
3 empty 2.37 65.3 18.2 No No
4 empty 2.48 47.3 16.1 No No
5 empty 2.41 63.7 13.6 No No
6 empty 2.5 58.8 9.6 No No
7 empty 2.21 72.2 6.2 No No
8 empty 2.29 62.6 8.7 No No
9 empty 1.96 67.8 6.7 No No
10 empty 2.02 58.9 9.5 No No
5V71_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 62.5 27.2 Yes No
2 bound 1.96 79.8 16.4 Yes Yes
3 empty 2.45 63.2 19 No No
4 empty 2.41 57.9 14.9 No No
5 empty 2.23 57.6 13.6 No No
6 empty 2.16 68.4 10.6 No No
7 empty 2.77 63.3 10.5 No No
8 empty 2.58 57.6 8.3 No No
9 empty 2.59 70.8 6.8 No No
10 empty 2.16 61 9.3 No No
5WHB_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 71.4 31.2 Yes Yes
2 bound 1.71 71.5 15.6 Yes No
3 empty 2.42 69.6 17.8 No No
4 empty 2.32 71.3 9.9 No No
5 empty 2.39 59.4 12.2 No No
6 empty 2.43 63.9 11.9 No No
7 empty 2.84 63.7 12.5 No No
8 empty 2.47 57.4 10.1 No No
9 empty 2.33 62.9 9 No No
10 empty 2.53 63.2 8.1 No No
6QUV_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 74.3 34.9 Yes No
2 bound 2.13 69.5 10.6 No No
3 empty 2.56 77.4 9.7 No No
4 empty 2.17 65 7.5 No No
5 empty 1.97 69.3 10.4 No No
6 empty 2.3 59.4 13.6 No No
7 empty 2.35 63.7 9.3 No No
8 empty 2.63 51.9 9.2 No No
9 empty 3.02 62.1 11 No No
10 empty 2.54 51.4 9.1 No No
5VQ8_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 69.3 22.7 No No
2 empty 2.43 64 19.9 No No
3 empty 2.43 70.4 13.8 No No
4 empty 2.3 66.4 12.3 No No
5 empty 2.22 53.4 9.8 No No
6 empty 2.75 67.3 11.1 No No
7 empty 2.42 56 11.8 No No
8 empty 2.22 63.4 12.1 No No
9 empty 2.53 63.4 7.7 No No
10 empty 2.81 61.2 7.6 No No
5V6S_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 82.4 18.9 Yes Yes
2 empty 2.63 60 29.9 No No
3 empty 2.38 72.7 17.7 No No
4 empty 2.14 60.5 13.4 No No
5 empty 2.22 64.5 12.7 No No
6 empty 2.46 56.9 13.7 No No
7 empty 2.29 63.9 8.4 No No
8 empty 2.55 63.2 8.3 No No
9 empty 2.62 65.6 9.3 No No
10 empty 2.8 57.5 10.8 No No
5KYK_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 67.6 34.7 Yes Yes
2 empty 2.58 63.1 22.8 No No
3 empty 2.01 66.8 13 No No
4 empty 2.06 64.8 11.4 No No
5 empty 2.58 59.3 10.9 No No
6 empty 2.79 57.6 11 No No
7 empty 2.51 73.7 8.5 No No
8 empty 2.77 61.1 6.7 No No
9 empty 2.7 65.9 7.1 No No
10 empty 2.3 57.9 7.5 No No
6MBU_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 69 33 Yes No
2 empty 2.36 69.4 11.1 No No
3 empty 2.17 58 13.7 No No
4 empty 2.37 60.2 15.2 No No
5 empty 2.13 73 10.6 No No
6 empty 2.64 70.1 10.1 No No
7 empty 2.95 59.5 10 No No
8 empty 2.64 52.1 8.4 No No
9 empty 1.91 98.2 0 Yes No
10 empty 1.55 70.3 5.2 No No
5WHD_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 64.4 26.1 Yes No
2 empty 2.32 64.6 20.2 No No
3 empty 2.56 68.9 16.8 No No
4 empty 2.35 69.1 10.8 No No
5 empty 2.41 64.1 8.5 No No
6 empty 2.21 60.7 8 No No
7 empty 1.93 66.4 7.3 No No
8 empty 2.31 57.4 11.5 No No
9 empty 2.94 61.6 6.9 No No
10 bound 1.6 72 6.8 No No
6P8Y_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 72.5 36.5 Yes No
2 empty 2.27 66.8 19.9 No No
3 empty 2.6 61.6 18 No No
4 empty 2.16 69.4 12 No No
5 empty 2.3 67.1 12.4 No No
6 empty 2.27 58.1 14.6 No No
7 empty 2.5 55.5 11.6 No No
8 empty 3.04 68.6 7.8 No No
9 empty 3.34 60.7 6.3 No No
10 empty 2.46 59.1 9.8 No No
5VPI_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 73.8 23.1 Yes No
2 empty 2.18 64 12.3 No No
3 empty 2.25 67.2 18.4 No No
4 empty 2.53 75.1 10.4 No No
5 empty 2.44 57.7 11.4 No No
6 empty 2.89 50.7 8.3 No No
7 empty 2 53.8 8.4 No No
8 empty 2.6 57.7 9.3 No No
9 empty 2.34 65.6 7.3 No No
10 empty 2.78 69.7 5.8 No No
5WLB_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 70.7 37.7 Yes Yes
2 empty 2.46 63.4 25.8 No No
3 empty 2.27 63.8 13.6 No No
4 empty 2.48 61 13.3 No No
5 empty 2.38 59.8 8.4 No No
6 empty 2.43 56.4 10.2 No No
7 empty 2.29 71.1 11.5 No No
8 empty 2.97 67.4 7.2 No No
9 empty 3.18 74.5 9.7 No No
10 empty 2.56 59 7.2 No No
6GOG_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.47 71.7 32.8 Yes No
2 empty 2.52 61.2 27.8 No No
3 empty 2.28 60.8 20.6 No No
4 empty 2.22 50 15.6 No No
5 empty 1.76 74.3 9.7 No No
6 empty 2.09 75 7 No No
7 empty 2.9 52.7 10.2 No No
8 empty 1.91 59.3 7.6 No No
9 empty 2.73 66.7 6.4 No No
10 empty 2.58 62.2 6.3 No No
6N2J_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 77.5 30.5 Yes No
2 empty 2.58 66.2 18.4 No No
3 empty 2.03 69.9 16.5 No No
4 empty 2.16 60.5 14 No No
5 empty 2.13 72.7 6.5 No No
6 empty 2.36 65.1 8.8 No No
7 empty 2.66 64.4 8.1 No No
8 empty 1.91 56.7 6.3 No No
9 empty 2.07 66.1 6.2 No No
10 empty 2.48 60.7 5.9 No No
4M1W_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 68.7 20.9 No No
2 empty 2.3 68.8 20.7 No No
3 empty 1.78 70.3 12.6 No No
4 empty 2.59 69.8 16.3 No No
5 empty 2.6 85.9 7.5 Yes No
6 empty 1.94 68.6 8.1 No No
7 empty 2.03 53.3 14.3 No No
8 empty 2.21 63.3 8.8 No No
9 empty 2.51 63.9 6.7 No No
10 empty 1.5 68.8 5.9 No No
5O2T_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 74.1 23.8 Yes Yes
2 empty 2.75 62.1 20.8 No No
3 empty 2.56 62.3 14 No No
4 empty 2.44 65.9 14.5 No No
5 empty 2.16 71.5 11.5 No No
6 empty 2.06 76.8 10.6 No No
7 empty 2.16 60.9 11.2 No No
8 empty 2.88 64.4 7.6 No No
9 empty 2.22 51.6 8.7 No No
10 empty 2.42 57.1 8 No No
3GFT_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 75.5 20.1 Yes Yes
2 empty 2 65.2 22.9 No No
3 empty 2.18 50.9 19.3 No No
4 empty 2.4 63.8 21.4 No No
5 empty 1.82 67.7 9.9 No No
6 empty 2.34 64.2 13.5 No No
7 empty 1.73 59.4 14.4 No No
8 empty 2.41 60 9.9 No No
9 empty 2 60.4 6.2 No No
10 empty 1.52 70.8 6.4 No No
6FA4_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.42 69.6 35.1 Yes Yes
2 empty 2.2 48.3 18.1 No No
3 empty 2.5 64.2 20.8 No No
4 empty 2.06 68.8 12.1 No No
5 empty 2.47 61.9 10.6 No No
6 empty 2.15 59.2 8.5 No No
7 empty 1.91 70.8 11.7 No No
8 empty 1.81 59.5 8.7 No No
9 empty 2.7 61 8.2 No No
10 empty 1.77 68.4 8.2 No No
6FA1_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.3 72.1 34.8 Yes Yes
2 empty 2.74 64.4 24.1 No No
3 empty 2.22 51.8 18.3 No No
4 bound 1.88 72.6 11.9 No No
5 empty 2.21 63.3 13.9 No No
6 empty 2.06 68.4 12.9 No No
7 empty 1.91 75.7 6.9 No No
8 empty 2.92 70.8 6.2 No No
9 empty 3.43 68.3 0 No No
10 empty 2.68 66 6.8 No No
5USJ_D GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 73.9 24.7 Yes No
2 empty 2.53 62.9 23 No No
3 empty 2.58 68.6 16.9 No No
4 empty 2.85 69.4 15.9 No No
5 empty 2.36 55.2 12.1 No No
6 empty 2.2 61.6 17.2 No No
7 empty 2.71 65 15.8 No No
8 empty 1.94 72.4 9.8 No No
9 empty 2.25 63.2 9.4 No No
10 empty 2.48 49.3 8.2 No No
6GQT_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 80.8 14.1 Yes Yes
2 empty 2.16 64.3 15.6 No No
3 empty 2.4 51.2 19.2 No No
4 empty 2.51 58.8 11.9 No No
5 empty 2.43 71.4 9 No No
6 empty 2.24 65.2 10.8 No No
7 empty 2.04 72.6 8.9 No No
8 bound 2.17 67.8 10.1 No No
9 empty 1.63 55.1 8.9 No No
10 empty 1.75 59.1 7.9 No No
5YY1_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 79.3 29.6 Yes Yes
2 bound 2.45 68.6 20 No No
3 empty 1.79 62.6 15.9 No No
4 empty 2.19 60.1 13.9 No No
5 empty 2.01 72.6 6.5 No No
6 empty 1.85 82.7 9.5 No No
7 empty 2.15 60.4 8.6 No No
8 empty 1.98 69.6 6.7 No No
9 empty 2.06 59.6 8.5 No No
10 empty 2.72 64.5 7.1 No No
6GQW_F GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 75.3 24 Yes No
2 empty 2.33 54 18.6 No No
3 empty 2.45 65.2 18.6 No No
4 bound 2.24 69.5 12.6 No No
5 empty 2.31 63.6 12.7 No No
6 empty 2.09 65 11.4 No No
7 empty 1.98 71.7 8.1 No No
8 empty 2.46 63.3 9.8 No No
9 empty 2.44 62.3 8.4 No No
10 empty 2.32 58.8 5.4 No No
6FA3_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 71 30.8 Yes Yes
2 empty 2.63 62.6 30.3 No No
3 empty 2.4 52.8 20.3 No No
4 empty 2.14 61.4 16.5 No No
5 empty 2.11 74.5 11 No No
6 empty 2 68.8 11.3 No No
7 empty 2.8 62.9 10.1 No No
8 empty 1.56 70.9 6 No No
9 empty 2.71 61.8 5 No No
10 empty 2.46 64.5 7.4 No No
6P8Z_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 75.4 21.8 Yes No
2 bound 2.19 72.8 16.5 No No
3 empty 2.14 66.3 15.8 No No
4 empty 2.36 67.7 19.5 No No
5 empty 2.38 64 15 No No
6 empty 2.12 65.8 9.2 No No
7 empty 2.46 53.7 14.5 No No
8 empty 2.91 62.7 10 No No
9 empty 2.55 74.5 9.4 No No
10 empty 2.22 65.4 6 No No
5VQ0_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 77.3 19.9 Yes No
2 empty 2.33 65.7 27.9 No No
3 empty 2.03 66.2 11.1 No No
4 empty 2.92 52.3 18.9 No No
5 empty 2.66 74.8 15.4 No No
6 empty 2.99 53.8 14.1 No No
7 empty 2.53 60.6 11.2 No No
8 empty 1.69 66.7 8.6 No No
9 empty 2.42 57 11.5 No No
10 empty 2.29 57.1 8.6 No No
6GOM_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 74.3 26.4 Yes No
2 empty 2.13 53.9 22.5 No No
3 empty 2.33 64.3 18.3 No No
4 empty 2.03 69.7 8.7 No No
5 empty 2.14 73.5 7.1 No No
6 empty 2.02 62.6 10.4 No No
7 empty 2.17 61.3 9.7 No No
8 empty 2.43 54 8.9 No No
9 empty 2.07 65.9 6.2 No No
10 empty 2.12 64.6 7.2 No No
6H46_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 66.4 23.5 No No
2 empty 2.62 63.7 25.5 No No
3 empty 2.46 67.8 22.7 No No
4 bound 1.6 71.5 15.2 No No
5 empty 2.64 59.6 9.1 No No
6 empty 2.09 60.9 12.3 No No
7 empty 2.55 58 8.8 No No
8 empty 2.76 62.1 11 No No
9 empty 2.89 60.6 8 No No
10 empty 2.42 63.9 9.8 No No
4DST_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 54.8 22.2 No No
2 bound 2.3 85.2 15.5 Yes Yes
3 bound 2.32 65.7 17.2 No No
4 bound 2.19 68.8 17.4 No No
5 bound 2 67 13.2 No No
6 empty 2.19 65 10 No No
7 empty 1.98 53 17.1 No No
8 empty 2.08 62 9.9 No No
9 empty 2.28 57.2 12.8 No No
10 empty 2.22 64.3 7.4 No No
6MBQ_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 70.9 25.8 Yes No
2 empty 2.62 63.6 31.1 No No
3 empty 1.94 65.4 14.9 No No
4 empty 2.51 64.9 10.5 No No
5 bound 2.43 70.3 14.3 No No
6 empty 2.72 53.2 8.8 No No
7 empty 2.52 61.3 8.9 No No
8 empty 2.85 61.8 6.8 No No
9 empty 2.48 70.2 5.9 No No
10 empty 2.89 80.4 0 No No
5O2S_G GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 68.4 22.5 No No
2 bound 1.91 76.5 20.8 No No
3 empty 2.4 76.7 11.7 No No
4 empty 2.19 65.6 12.8 No No
5 empty 2.56 71 12.4 No No
6 empty 2.27 61.5 10 No No
7 empty 2.31 71.6 8.7 No No
8 empty 1.93 58.8 11 No No
9 empty 2.42 50.6 13.6 No No
10 empty 2.25 64.4 8.8 No No
4M1T_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 71.3 22.5 Yes No
2 empty 2.14 61.5 18.6 No No
3 empty 2.61 67.5 26.5 No No
4 empty 2.41 71.6 15.3 No No
5 empty 2.14 62.6 8.8 No No
6 empty 2.05 73.3 7.5 No No
7 empty 2.54 65.8 5.5 No No
8 empty 1.83 64 7.5 No No
9 empty 2.03 62 7.1 No No
10 empty 2.95 68.1 6 No No
4M22_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 70.7 32.1 Yes Yes
2 empty 2.5 67 16.6 No No
3 empty 2.32 60.4 19.9 No No
4 empty 2.12 64 11.2 No No
5 empty 2.44 60.1 12.6 No No
6 empty 2.01 71.7 9.3 No No
7 empty 1.81 62.5 8.3 No No
8 empty 2.25 57.1 7.5 No No
9 empty 2.4 57.9 7.8 No No
10 empty 3.39 62.1 6.7 No No
6MQN_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 68.1 19.1 No No
2 empty 2.4 69.1 17.1 No No
3 empty 2.1 80 12.4 No No
4 empty 2 75 12 No No
5 empty 2.57 63.8 12.1 No No
6 empty 1.87 75.8 5.2 No No
7 empty 2.55 65.8 7.9 No No
8 empty 2.62 62 10.7 No No
9 empty 2.49 72.9 5.8 No No
10 empty 2.48 56.2 9.7 No No
6GQY_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.5 77.6 22.5 Yes No
2 empty 2.19 64 26.3 No No
3 empty 2.74 64.7 26.2 No No
4 bound 2.24 71.7 13.5 No No
5 empty 2.56 56.1 14.2 No No
6 empty 1.95 71.8 12.3 No No
7 empty 2.14 58.3 10.1 No No
8 empty 2.16 55.7 11.2 No No
9 empty 2.07 72.5 7.1 No No
10 empty 2.08 67 7 No No
6CC9_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.44 67.9 26 Yes Yes
2 bound 2.19 80.9 20.8 Yes Yes
3 empty 2.17 67.1 18.2 No No
4 empty 2.48 54.5 18 No No
5 bound 2.38 56.7 15.9 No No
6 bound 2.07 45 13.5 No No
7 empty 2.21 51.8 12.3 No No
8 empty 2.23 58.7 12.7 No No
9 bound 1.69 72.8 8.3 No No
10 empty 2.7 62.4 9.5 No No
4M21_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 70.9 27.7 Yes No
2 empty 2.37 66.9 16 No No
3 bound 1.81 71.7 13.3 No No
4 empty 1.97 72.4 8.8 No No
5 empty 2.2 56.1 9.1 No No
6 empty 2.18 56.3 9.5 No No
7 empty 2.1 52.9 8.8 No No
8 empty 1.87 63.6 5.9 No No
9 empty 2.51 58.7 7 No No
10 empty 1.07 62.7 6.6 No No
6QUW_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 72.7 31.6 Yes No
2 bound 2.14 66.9 13.7 No No
3 empty 2.59 57.6 21.5 No No
4 empty 2.47 79.5 7.3 No No
5 empty 2.19 70.4 10.6 No No
6 empty 2.38 67.9 7.6 No No
7 empty 2.36 63.1 8.4 No No
8 empty 2.08 100 0 Yes No
9 empty 3.04 54.7 10.9 No No
10 empty 2.74 61.2 7.3 No No
6OB2_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 73.7 28.7 Yes No
2 empty 1.83 66.7 19.1 No No
3 empty 1.68 67.1 22.8 No No
4 empty 2.21 68.9 10.5 No No
5 empty 2.44 60.6 12.3 No No
6 empty 1.48 86.7 13.2 Yes No
7 empty 2.62 62.3 9.2 No No
8 empty 2.74 66.1 7.7 No No
9 empty 1.18 95.8 0 Yes No
10 empty 2.73 74.8 0 No No
4LYF_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 69.1 22.1 No No
2 empty 2.49 68.9 16.9 No No
3 empty 1.97 61.2 15.6 No No
4 empty 2.71 76.3 14.4 No No
5 empty 2.01 60.8 14.4 No No
6 empty 1.96 73.9 7.2 No No
7 empty 2.15 62.8 8.7 No No
8 empty 1.63 64 7.4 No No
9 empty 2.58 53.3 8.9 No No
10 empty 2.81 61.1 5.9 No No
5V71_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 69.8 38.9 Yes No
2 empty 2.3 63.3 23.1 No No
3 empty 2.52 63 14.5 No No
4 empty 2.16 60.5 11.9 No No
5 empty 2.36 62.8 15.4 No No
6 empty 1.88 72.9 8.7 No No
7 empty 2.07 57.6 7.5 No No
8 empty 2.53 67.2 5.6 No No
9 empty 2.58 70.9 7.7 No No
10 empty 2.41 63.4 7.8 No No
6FA4_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 70 31.1 Yes Yes
2 empty 2.73 61.9 34.2 No No
3 empty 2.36 51.7 18.6 No No
4 bound 2.18 72.6 10.9 No No
5 empty 1.98 67.8 10.8 No No
6 empty 2.04 60.5 11.2 No No
7 empty 2.14 58 7.4 No No
8 empty 1.64 77.1 6.4 No No
9 empty 2.65 64.9 7.6 No No
10 empty 3.26 45.3 5.6 No No
5WHD_D GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.39 68.3 14.9 No No
2 empty 2.65 71.5 13 No No
3 empty 2.1 65.4 12.6 No No
4 empty 2.45 53.6 12.5 No No
5 bound 1.77 65.5 10 No No
6 empty 2.81 73.2 8.6 No No
7 empty 2.94 58.8 10.2 No No
8 empty 2.58 70.2 6.4 No No
9 empty 2.21 62.1 8.9 No No
10 bound 1.52 67.2 7.8 No No
4LYJ_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 75 29.5 Yes No
2 empty 2.38 65.7 20.6 No No
3 empty 1.89 65.4 13.3 No No
4 empty 2.34 80.7 18.4 No No
5 empty 2.28 67.1 13.6 No No
6 empty 2.37 59.3 15.9 No No
7 empty 2.07 69.5 8.6 No No
8 empty 2.88 71.9 9 No No
9 empty 2.44 64.5 6.8 No No
10 empty 2.37 70.7 6.5 No No
6F76_D GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 72 30.1 Yes No
2 empty 2.25 52.2 19.8 No No
3 empty 2.47 65.3 18.7 No No
4 empty 2.31 74.5 8.5 No No
5 empty 2.55 55 8.7 No No
6 empty 2.22 72.6 8.1 No No
7 empty 1.93 66.4 12.8 No No
8 empty 2.25 55.9 9.3 No No
9 empty 2.78 61 10.3 No No
10 empty 2.73 72 6.5 No No
6CU6_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 77.1 24.1 Yes No
2 empty 2.51 61 22.3 No No
3 empty 2.21 60.9 18.4 No No
4 empty 2.25 71.7 14.6 No No
5 empty 2.18 69.8 15.8 No No
6 empty 2.24 69.4 10.8 No No
7 empty 2.22 66.8 12.6 No No
8 empty 2.41 57.7 8 No No
9 empty 2.2 54.1 6.3 No No
10 empty 2.09 61.8 6.5 No No
3GFT_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 72.1 32.1 Yes No
2 empty 2.5 62.2 21.5 No No
3 empty 2.2 65.6 20.6 No No
4 empty 2.15 71.9 10 No No
5 empty 2.44 63.1 12.7 No No
6 empty 2.13 75 6.7 No No
7 empty 1.9 65.8 12.4 No No
8 empty 2.91 65.1 7 No No
9 empty 2.53 60.5 7.6 No No
10 empty 2.54 75.3 6.1 No No
6FA2_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 70.9 27.9 Yes No
2 empty 2.46 64.9 16.9 No No
3 bound 2.09 73.8 10 No No
4 empty 2.47 50.6 16 No No
5 empty 2.16 73.8 9.3 No No
6 empty 1.98 59.8 9.5 No No
7 empty 2.02 72.7 8.1 No No
8 empty 1.94 59.6 11.5 No No
9 empty 2.49 63.1 11.8 No No
10 empty 2.15 65.4 8 No No
4PZY_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.46 70.1 30.8 Yes Yes
2 bound 2 75.9 20.7 No No
3 empty 2.31 71.2 16.1 No No
4 empty 2.35 57.1 16.8 No No
5 empty 2.06 54.5 13.6 No No
6 empty 2.41 54.6 12.3 No No
7 empty 1.98 67.3 10.5 No No
8 empty 2.95 44.8 8.8 No No
9 empty 2.83 63 10.6 No No
10 empty 2.8 57.6 11.4 No No
5F2E_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.3 79.3 28.9 Yes Yes
2 bound 2.37 59.5 20.3 No No
3 empty 2.41 60.7 21 No No
4 empty 2.26 72.9 13.1 No No
5 empty 2.55 63.8 10 No No
6 empty 2.32 58.4 12.1 No No
7 empty 2.47 64.1 11.7 No No
8 bound 2.09 68.1 7.3 No No
9 bound 2.33 59.3 7.6 No No
10 empty 2.69 75.5 6.1 No No
5V6V_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 75.9 34.6 Yes Yes
2 empty 2.22 66.7 14.1 No No
3 empty 2.25 65.6 11.9 No No
4 empty 2.75 58.8 9.8 No No
5 empty 2.14 60.8 7.6 No No
6 empty 2.55 62.2 7.9 No No
7 empty 2.22 58 7.2 No No
8 empty 2.75 58.9 8.7 No No
9 empty 2.83 74.3 6.9 No No
10 empty 1.93 64.9 7.9 No No
4LRW_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 72.1 25 Yes No
2 empty 2.37 67 14.1 No No
3 empty 2.21 68.3 11.7 No No
4 empty 1.92 69.9 10.5 No No
5 empty 2.52 59 11.4 No No
6 empty 2.14 67.6 7.9 No No
7 empty 2.33 59.2 9.1 No No
8 empty 2.11 59.2 12.2 No No
9 empty 2.84 70.5 7.8 No No
10 empty 2.94 72 8.4 No No
5WPM_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 68.6 31.9 Yes Yes
2 empty 2.54 65.8 12.9 No No
3 bound 1.55 75.9 9.5 No No
4 empty 2.51 56.8 11.4 No No
5 empty 1.91 63.5 8.5 No No
6 empty 2.38 89.6 9 Yes No
7 empty 2.31 61.2 9.4 No No
8 empty 1.49 71.3 5.6 No No
9 empty 2.25 57.3 7.4 No No
10 empty 3.23 72.7 7.9 No No
6F76_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 70.2 38.1 Yes No
2 empty 2.47 67.6 18.6 No No
3 empty 2.37 49.9 19.4 No No
4 bound 2.31 65.9 21 No No
5 empty 2.01 69.3 8.1 No No
6 empty 1.5 64.5 9.9 No No
7 empty 1.78 59.3 6.4 No No
8 empty 1.89 63.1 8.2 No No
9 empty 2.34 56.8 7.6 No No
10 empty 2.56 69.9 6.3 No No
5VBM_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 80.4 19.1 Yes Yes
2 bound 2.29 66.9 23.9 No No
3 empty 2.3 64 20.5 No No
4 empty 1.93 66.6 16.2 No No
5 empty 2.32 65.1 13.7 No No
6 empty 2.45 64.9 11.3 No No
7 empty 2.33 66.5 8.2 No No
8 empty 2.87 58.6 10.7 No No
9 empty 2.56 69.1 7.2 No No
10 empty 2.03 71 7.3 No No
4DSU_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 74.8 23 Yes Yes
2 empty 2.1 66.4 23.2 No No
3 bound 2.22 65.3 14.3 No No
4 empty 2.04 56.3 13.5 No No
5 empty 2.49 63 15.9 No No
6 empty 2.29 68.3 11.9 No No
7 empty 2.62 56.2 7.6 No No
8 empty 2.24 67.5 6.7 No No
9 empty 2.33 57.5 6.6 No No
10 empty 2.75 64 6.9 No No
5VQ1_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 70.2 31.7 Yes No
2 empty 2.47 68.1 18.3 No No
3 empty 2.92 63.2 17.2 No No
4 empty 2.06 64.7 11.5 No No
5 empty 2.34 57.1 17.4 No No
6 empty 2.44 61 13.6 No No
7 empty 2.37 62.6 12.2 No No
8 empty 1.61 69.1 8.6 No No
9 empty 3.11 59.4 8.5 No No
10 empty 2.25 56.2 7.8 No No
6P8W_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 79.2 30.8 Yes Yes
2 empty 2.34 61.1 18.6 No No
3 empty 2.31 61.7 20.4 No No
4 empty 2.56 63.9 14.9 No No
5 empty 2.28 72.6 10.4 No No
6 empty 2.42 60.7 13 No No
7 empty 2.28 64.8 12.9 No No
8 empty 2.85 85.5 9.2 Yes No
9 empty 2.77 57.3 8.4 No No
10 empty 2.76 69.9 7.3 No No
6B0Y_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 84.7 18 Yes Yes
2 bound 2 74.9 19.3 No No
3 empty 2.39 64.7 16.5 No No
4 empty 2.32 69.9 10 No No
5 empty 1.94 52.5 10.8 No No
6 empty 2.19 61.6 9.9 No No
7 empty 2.79 66.4 8.1 No No
8 empty 2.41 60.5 8.9 No No
9 empty 2.22 57.9 7.9 No No
10 empty 1.78 62.6 8.3 No No
5UFQ_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 67 31.1 Yes No
2 empty 2.58 68.3 17.5 No No
3 empty 1.92 58.4 18 No No
4 empty 2.27 72.8 14.4 No No
5 empty 1.93 75.2 9 No No
6 empty 2.36 68.2 13.8 No No
7 empty 2.44 57.6 8 No No
8 empty 2.28 55 7.1 No No
9 empty 1.73 58 8.6 No No
10 empty 3.01 61.7 6.9 No No
6B0Y_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 80.8 19.7 Yes Yes
2 bound 1.9 78.9 19.1 Yes Yes
3 empty 2.49 67 21.4 No No
4 empty 2.24 64.3 15 No No
5 empty 2.24 60.2 10.9 No No
6 empty 1.86 67.6 12.9 No No
7 empty 2.21 71.3 8.4 No No
8 empty 2 61.5 10.9 No No
9 empty 2.98 54.9 7.7 No No
10 empty 2.13 61 8.6 No No
5OCT_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 70.4 25.3 Yes No
2 empty 2.58 63.7 18 No No
3 empty 2.21 61.9 20 No No
4 bound 2.28 72.1 16.8 No No
5 empty 2.51 55.4 15.4 No No
6 bound 2.39 62 10.7 No No
7 empty 1.88 72.8 8 No No
8 empty 2.42 60.4 13.3 No No
9 empty 2.35 53.7 9.3 No No
10 empty 3.02 67.7 5.7 No No
6GQY_F GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 73.6 29.2 Yes No
2 empty 2.43 65.4 24.4 No No
3 empty 2.64 65 23.5 No No
4 empty 2.3 54.8 18.3 No No
5 empty 2.02 68.3 12.3 No No
6 empty 2.08 71.6 7.4 No No
7 empty 2.27 53 9 No No
8 empty 2.13 62.5 7.3 No No
9 empty 2.82 63.5 8 No No
10 empty 1.98 62.8 6.2 No No
6GQX_F GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 65.9 21.9 No No
2 empty 2.28 65.7 24.7 No No
3 empty 2.64 62.7 25.7 No No
4 empty 2.38 50.9 18.2 No No
5 empty 2.16 67.1 10.3 No No
6 empty 2.33 62.5 13.2 No No
7 empty 2.19 72.4 6.4 No No
8 empty 2.86 63.4 7.7 No No
9 empty 2.98 69.2 6.2 No No
10 empty 2.17 64.8 5.4 No No
5WHB_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.3 69.6 31.5 Yes Yes
2 empty 2.69 67.7 20.5 No No
3 bound 1.77 71.2 14.3 No No
4 empty 2.33 63.8 17.5 No No
5 empty 2.39 80.1 9.5 No No
6 empty 2.34 61.1 14 No No
7 empty 2.22 59.7 12 No No
8 empty 2.31 73.3 6.7 No No
9 empty 2.52 58.1 10.6 No No
10 empty 2.84 57.1 9.9 No No
6MBT_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 71.5 32.4 Yes Yes
2 empty 2.48 63.4 25.3 No No
3 empty 2.63 62.2 15.1 No No
4 empty 3.01 61.7 7.9 No No
5 empty 1.9 69.9 8.9 No No
6 empty 2.95 65.5 8.1 No No
7 empty 2.58 65.4 7.2 No No
8 empty 2.19 54.7 8 No No
9 empty 2.37 62.2 5.5 No No
10 empty 2.49 81.4 0 No No
5USJ_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 73.1 24.4 Yes No
2 empty 2.59 64.8 23.3 No No
3 empty 2.15 54.2 13.7 No No
4 empty 2.16 70.4 17.9 No No
5 empty 2.22 68 11.4 No No
6 empty 2.03 56.9 17.3 No No
7 empty 1.76 69.3 8 No No
8 empty 2.56 71 7.6 No No
9 empty 2.43 59.9 9.2 No No
10 empty 1.78 65.4 7.8 No No
6GQW_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 71.8 29 Yes No
2 empty 2.57 62.2 26.5 No No
3 bound 2.31 72.4 11 No No
4 empty 2.52 51.4 12.6 No No
5 empty 2.09 58.1 11 No No
6 empty 2.24 52.6 10.3 No No
7 empty 2.06 73.8 8.3 No No
8 empty 2.49 68.9 8 No No
9 empty 3.05 70.3 5 No No
10 empty 2.08 61.6 7.9 No No
5OCO_F GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.41 72.2 27.1 Yes No
2 empty 2.24 67.3 16.9 No No
3 empty 2.67 65.6 18.1 No No
4 empty 2.32 52.3 18.2 No No
5 bound 1.94 69.5 9.8 No No
6 empty 2.36 64.3 10.8 No No
7 empty 2.11 67.3 12.9 No No
8 empty 1.93 73.9 6.9 No No
9 empty 2.49 54.4 7.1 No No
10 empty 3.09 67.6 4.8 No No
6EPP_R GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 68.8 20.6 No No
2 empty 2.3 60.7 26 No No
3 bound 2.42 64.4 20.6 No No
4 empty 2.6 64.8 21.5 No No
5 empty 1.93 59.7 20.1 No No
6 empty 2.14 59.7 16 No No
7 empty 2.1 98.8 0 Yes No
8 empty 2.42 59.9 11.6 No No
9 empty 2.21 69.1 8.6 No No
10 empty 1.8 70.8 10.7 No No
6GQT_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 70.8 36.2 Yes Yes
2 empty 2.56 62.4 24.8 No No
3 empty 2.53 52.2 18.5 No No
4 bound 2.03 76 12 No No
5 empty 2.16 58.6 18.7 No No
6 empty 2.04 71.5 6.9 No No
7 empty 2.06 65.4 7.8 No No
8 empty 3.13 60.7 6.8 No No
9 empty 3.2 62.2 6.9 No No
10 empty 2.83 57.4 5.6 No No
6MQN_B GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 69.2 23.6 No No
2 empty 2.35 65.3 18.1 No No
3 empty 2.26 74.8 10.1 No No
4 empty 2.34 63.4 9.4 No No
5 empty 2.25 63.5 9.1 No No
6 empty 2.3 63.5 12.3 No No
7 empty 2.07 69.3 6.6 No No
8 empty 2.48 55.1 10.6 No No
9 empty 2.92 55.8 9.1 No No
10 empty 2.6 67.1 7.7 No No
5UK9_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 68.5 29.2 Yes Yes
2 empty 2.48 66.7 26.2 No No
3 empty 2.25 68.1 9 No No
4 empty 2.27 71.6 10.2 No No
5 empty 2.4 60.9 12.4 No No
6 empty 2.04 63.6 9.6 No No
7 empty 2.61 71.2 8.7 No No
8 empty 2.33 58.7 9.6 No No
9 empty 2.71 58.7 7.7 No No
10 empty 2.55 55.4 8 No No
4M1O_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.27 66.8 21.2 No No
2 empty 2.52 66.6 30.2 No No
3 empty 2.52 71.2 13.8 No No
4 empty 1.96 64.3 14.5 No No
5 empty 2.01 71.2 8.1 No No
6 empty 2.15 63.6 9.3 No No
7 empty 2.58 64.4 5.6 No No
8 empty 2.84 64.3 5.4 No No
9 empty 2.11 60.1 8.1 No No
10 empty 1.52 72.2 6.3 No No
3GFT_D GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.41 65.4 20.4 No No
2 empty 2.34 67.2 16 No No
3 empty 2.57 62.5 12.9 No No
4 empty 1.98 68.2 10.9 No No
5 empty 2.05 69.5 11.2 No No
6 empty 2.17 79.2 9 No No
7 empty 2.49 63.6 9.5 No No
8 empty 2.54 69.8 6.6 No No
9 empty 2.74 56.2 9.8 No No
10 empty 2.11 55.2 9.1 No No
4LYH_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 75.1 19.5 Yes No
2 bound 2.1 75.5 17.9 No No
3 empty 2.24 66.2 17.6 No No
4 empty 2.3 62.8 8.5 No No
5 empty 2.04 74.3 7.6 No No
6 empty 2.47 59 14.5 No No
7 empty 2.59 72.7 5.6 No No
8 empty 1.39 67.2 6.5 No No
9 empty 2.54 51.8 6 No No
10 empty 2.36 56.8 6.2 No No
5VP7_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 71.6 30.6 Yes Yes
2 empty 2.58 71 12.7 No No
3 empty 2.71 68.6 19.4 No No
4 empty 1.86 66.2 12.8 No No
5 empty 2.37 59.4 16.6 No No
6 empty 2.32 60.4 10.4 No No
7 empty 1.83 70.7 8 No No
8 empty 2.76 57.5 7.7 No No
9 empty 3.27 56.8 8.1 No No
10 empty 2.95 54.9 10.3 No No
5OCO_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 73.3 21.4 Yes No
2 empty 2.45 63.1 22.2 No No
3 empty 2.29 60.9 21.2 No No
4 empty 2.38 67.1 17.3 No No
5 empty 2.34 50.9 13.3 No No
6 bound 1.91 75.9 10.1 No No
7 empty 2.46 56.7 10.9 No No
8 empty 2.08 75.5 9.5 No No
9 empty 2.89 57.6 7.9 No No
10 empty 3.07 68.5 5.8 No No
4DSO_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.47 78.9 23.6 Yes Yes
2 empty 2.29 64.5 18.2 No No
3 bound 2.43 64.1 18.1 No No
4 empty 2.15 56.2 16.7 No No
5 empty 1.87 52.5 13.7 No No
6 bound 2.4 67.6 10.4 No No
7 empty 1.72 69.5 11 No No
8 empty 2.4 58.5 17.9 No No
9 empty 2.56 71.3 8.1 No No
10 empty 2.8 64.1 7.6 No No
4LUC_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 76.5 39.2 Yes Yes
2 empty 2.27 71.3 11.2 No No
3 empty 1.63 77.6 8.7 No No
4 empty 2.46 67.4 11.5 No No
5 empty 1.89 60.1 10.7 No No
6 empty 2.26 57.7 10.4 No No
7 empty 2.75 62.7 6.9 No No
8 empty 2.26 61.6 7.3 No No
9 empty 2.56 65.1 7.4 No No
10 empty 2.43 58.9 7.8 No No
6FA1_E GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.55 71.5 37.5 Yes Yes
2 empty 2.57 67.9 17.3 No No
3 empty 2.13 48.7 17.6 No No
4 empty 2.3 62.9 15.8 No No
5 empty 2.54 56.8 9.5 No No
6 empty 1.92 72.9 6 No No
7 empty 2.77 65.9 5.2 No No
8 empty 2.36 52.1 8.5 No No
9 empty 1.93 68.9 6.6 No No
10 empty 2.16 55.6 6.5 No No
6EPL_R GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.77 68 21.2 No No
2 empty 2.28 60.8 21.4 No No
3 empty 2.53 65.5 22.3 No No
4 empty 2.09 62.4 20 No No
5 empty 2.45 69 16.8 No No
6 empty 2.41 62.3 18.7 No No
7 empty 2.15 59.4 16.1 No No
8 empty 2.2 99.6 0 Yes No
9 empty 1.79 71.2 11.5 No No
10 empty 2.35 64.4 11.3 No No
4M1O_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 69.5 16.2 No No
2 bound 1.69 70.9 12.4 No No
3 empty 2.54 69.7 20.3 No No
4 empty 2.18 65.3 11.8 No No
5 empty 2.11 70.4 10 No No
6 empty 2.55 55.7 13.9 No No
7 empty 1.84 61.9 10.2 No No
8 empty 2.58 53.5 8.5 No No
9 empty 2.21 69.6 6.6 No No
10 empty 2.07 68.2 7.5 No No
6BP1_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 69.6 23.6 Yes Yes
2 empty 2.63 68.3 20.3 No No
3 empty 2.24 58.1 18.7 No No
4 empty 1.91 71.9 14.2 No No
5 empty 2.31 59.5 16.5 No No
6 empty 2.5 82 14.8 No No
7 empty 2.49 71.7 9.4 No No
8 empty 2.21 67.1 9.8 No No
9 empty 2.09 73.7 10 No No
10 empty 2.86 64.3 6.6 No No
4Q02_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 65.4 31.9 Yes No
2 bound 2.17 76.4 15.4 No No
3 empty 2.27 60.8 20.7 No No
4 empty 2.04 55.9 16.4 No No
5 empty 2.85 53.9 9.8 No No
6 empty 1.98 60.7 9.1 No No
7 empty 2.46 52.2 12.6 No No
8 empty 2.85 63.9 8.5 No No
9 empty 1.7 65.4 6.8 No No
10 empty 1.98 57.4 7.6 No No
6P0Z_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.29 71.5 35.3 Yes Yes
2 empty 2.19 63 15.3 No No
3 empty 2.38 70.5 17.1 No No
4 empty 2.69 59.6 17 No No
5 empty 1.9 72.1 6.9 No No
6 empty 2.91 63.4 9.4 No No
7 bound 2.59 57.1 12.4 No No
8 empty 2.31 66.5 7 No No
9 empty 2.55 73.7 6.4 No No
10 empty 2.75 67.9 9.6 No No
5MLB_G GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 68.4 22.5 No No
2 bound 1.91 76.5 20.8 No No
3 empty 2.4 76.7 11.7 No No
4 empty 2.19 65.6 12.8 No No
5 empty 2.56 71 12.4 No No
6 empty 2.27 61.5 10 No No
7 empty 2.31 71.6 8.7 No No
8 empty 1.93 58.8 11 No No
9 empty 2.42 50.6 13.6 No No
10 empty 2.25 64.4 8.8 No No
6BOF_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.36 59 27.9 Yes No
2 empty 2.19 64.3 23.7 No No
3 empty 2.63 62.9 27.4 No No
4 bound 2.19 64.4 20.8 No No
5 empty 2.35 58.4 12.9 No No
6 empty 2.74 58.9 13.1 No No
7 empty 1.99 68.1 10.2 No No
8 empty 2.24 69.4 9.1 No No
9 bound 2.13 70.8 8.3 No No
10 empty 2.49 60.8 8.5 No No
6MBU_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 65.9 24 Yes No
2 bound 2.01 77 18.5 No No
3 empty 2.31 62.6 18.6 No No
4 empty 2.24 59.8 13.3 No No
5 empty 2 69.2 9.1 No No
6 empty 2.15 57.2 12.2 No No
7 empty 2.33 68.2 9.2 No No
8 empty 2.59 57.5 15.5 No No
9 empty 2.58 62.8 8.8 No No
10 empty 2.64 59 7.6 No No
6GOM_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 80.9 21.1 Yes Yes
2 empty 2.14 59.6 16.7 No No
3 empty 2.44 46.9 16.6 No No
4 empty 2.49 57.6 14.1 No No
5 bound 2.22 68.1 14.6 No No
6 empty 2.31 69.9 9.2 No No
7 empty 1.51 57 9.1 No No
8 empty 2 52.6 11.9 No No
9 empty 1.89 52.1 10.4 No No
10 bound 2.18 64.9 8.3 No No
4M21_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 67.7 34.8 Yes No
2 empty 2.33 72.4 15.2 No No
3 empty 1.96 59.9 13.7 No No
4 empty 2.03 71.1 8.3 No No
5 empty 2.17 65.9 10 No No
6 empty 2.77 62.5 5.6 No No
7 empty 1.63 64.4 7.1 No No
8 empty 2.36 68.6 7.9 No No
9 empty 2.47 60.3 7.7 No No
10 empty 2.55 62.3 6.6 No No
6GQX_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 77.6 19.9 Yes No
2 empty 2.67 65.7 18.2 No No
3 bound 2.16 73.8 11.1 No No
4 empty 2.23 62 16.3 No No
5 empty 2.45 52.6 15 No No
6 empty 2.18 56.7 9.4 No No
7 empty 2.03 73.4 10.4 No No
8 empty 2.16 63.3 10.5 No No
9 empty 2.17 72.8 6.4 No No
10 empty 2.82 60.4 8.8 No No
5WLB_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 71.9 27.3 Yes No
2 bound 2.07 68.6 20 No No
3 empty 2.38 60.7 13.2 No No
4 empty 2.58 71.5 16.6 No No
5 empty 2.56 62.1 15.3 No No
6 empty 2.41 64.3 12 No No
7 empty 2.39 66 13.2 No No
8 empty 2.97 68.9 6.9 No No
9 empty 2.56 60.4 9.1 No No
10 empty 2.4 45 6.5 No No
5USJ_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.62 69.6 37 Yes Yes
2 empty 2.41 57.5 20.5 No No
3 empty 2.55 69.3 16.1 No No
4 empty 2.18 68 14.3 No No
5 empty 2.01 75.2 6.1 No No
6 empty 2.4 59.2 11.1 No No
7 empty 2.37 62 8 No No
8 empty 2.68 59 7.6 No No
9 empty 2.28 60.4 8.1 No No
10 empty 2.65 65.4 7.4 No No
4L8G_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 78.3 17.7 Yes No
2 empty 2.2 69.9 12.8 No No
3 empty 2.35 67.3 15.3 No No
4 empty 2.08 69.8 11 No No
5 empty 1.97 74.5 7.9 No No
6 empty 2.42 55.2 11.7 No No
7 empty 2.29 58.8 11.8 No No
8 empty 2.6 70.8 8.7 No No
9 empty 2.62 66 8.5 No No
10 empty 2.37 61.8 7.4 No No
5WHE_J GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 73 30.7 Yes Yes
2 empty 2.64 65.2 18.3 No No
3 empty 2.25 66.2 12.1 No No
4 bound 1.58 73 9.3 No No
5 empty 2.65 59.3 13.4 No No
6 empty 2.43 68.4 10.8 No No
7 empty 2.57 61.5 7.1 No No
8 empty 2.33 61.8 10.9 No No
9 empty 2.24 77.4 8.8 No No
10 empty 2.15 56 8.1 No No
6FA4_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 70.2 30.7 Yes No
2 empty 2.23 68.2 18.6 No No
3 empty 2.63 65.5 25.8 No No
4 bound 2.07 65.6 23.8 No No
5 bound 2.18 51.6 18.2 No No
6 empty 2.1 64.2 11.1 No No
7 empty 1.94 69.8 8.8 No No
8 empty 2.89 63.9 7.9 No No
9 empty 2.64 57.4 7.9 No No
10 empty 1.87 69.1 6 No No
6GQY_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 76.6 24.3 Yes Yes
2 bound 2.41 63.2 31.3 No No
3 empty 2.64 65.8 23.6 No No
4 empty 2.47 49.1 15.8 No No
5 empty 1.79 61.4 11.7 No No
6 empty 1.93 72.5 7.9 No No
7 empty 2.46 56.5 7.5 No No
8 empty 1.67 70.2 7.4 No No
9 empty 2.26 61.8 6.2 No No
10 empty 2.31 71.2 5.7 No No
5VPZ_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 68.6 25.9 Yes No
2 empty 1.87 66.7 14.5 No No
3 empty 2.29 67.1 17.3 No No
4 empty 2.58 71.4 17.3 No No
5 empty 2.59 58.7 15.8 No No
6 empty 2.54 55.1 9.7 No No
7 empty 2.97 60.2 11.2 No No
8 empty 2.21 60.7 9.7 No No
9 empty 1.68 62.4 7.2 No No
10 empty 2.5 59.4 6.8 No No
5VQ8_B GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 70.4 23.7 No No
2 empty 2.37 60.9 25 No No
3 empty 2.13 72.1 10.8 No No
4 empty 2.35 64.9 17.3 No No
5 empty 2.78 69.6 10.3 No No
6 empty 2.63 63.5 8.2 No No
7 empty 2.46 53.5 11.1 No No
8 empty 2.24 61.5 9.1 No No
9 empty 2.5 66.9 8.4 No No
10 empty 3.06 63.2 5.5 No No
6GOD_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 83.5 19.5 Yes Yes
2 empty 2.25 69.5 19 No No
3 bound 2.38 65.1 15.8 No No
4 empty 2.14 61 15.6 No No
5 empty 1.93 57.4 13.9 No No
6 empty 2.41 71.6 10.6 No No
7 empty 2.21 73.3 10.5 No No
8 empty 1.67 65.4 10.3 No No
9 empty 2.42 65.8 8.4 No No
10 empty 1.84 48.3 8 No No
6GOG_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.45 74.1 31.1 Yes No
2 bound 2.29 67.2 21.3 No No
3 empty 2.36 66.7 17.7 No No
4 empty 2.68 51 20.3 No No
5 empty 2.35 69.6 15.7 No No
6 empty 1.82 62.6 12.9 No No
7 empty 2.25 63.1 8.9 No No
8 empty 2.07 74.9 6.7 No No
9 empty 2.12 65 9.3 No No
10 empty 2.2 65.2 5.9 No No
4LV6_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 79.3 28 Yes Yes
2 empty 2.3 63.7 23.4 No No
3 empty 2.34 69.6 11.9 No No
4 empty 1.95 78.2 9 No No
5 empty 1.81 56.5 10.3 No No
6 empty 2.58 62.2 8.5 No No
7 empty 2.27 61.5 8.4 No No
8 empty 2.05 60.7 8.2 No No
9 empty 2.46 69.2 7.3 No No
10 empty 2.52 61.4 5.1 No No
6GQW_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 72 23.2 Yes Yes
2 empty 2.61 62.7 26.9 No No
3 empty 2.49 55.2 19 No No
4 empty 2.42 67.5 12.6 No No
5 empty 2.19 56.1 11 No No
6 empty 1.91 69.4 9.8 No No
7 empty 2.83 59 11.9 No No
8 empty 2.24 66.2 5.6 No No
9 empty 1.83 59.4 8.8 No No
10 empty 2 57.6 7 No No
6QUV_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.44 76.6 23.2 Yes Yes
2 empty 2.19 70.1 12.5 No No
3 empty 2.17 62.7 12.5 No No
4 empty 2.48 62.7 14 No No
5 empty 2.24 62 11.9 No No
6 empty 2.34 62.5 11.2 No No
7 empty 2.57 56.1 16.4 No No
8 empty 2.33 65 12.9 No No
9 empty 2.26 66.3 12.1 No No
10 empty 2.68 63.7 9.4 No No
6FA1_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 69 32.4 Yes No
2 empty 2.64 66.7 26.2 No No
3 bound 2.31 65.4 19.7 No No
4 empty 2.16 53 19.1 No No
5 empty 2.37 68.9 14 No No
6 empty 1.86 73.5 10.1 No No
7 empty 1.42 61.8 12.3 No No
8 empty 2.11 78.3 6.7 No No
9 empty 2.7 63.6 6.2 No No
10 empty 2.28 67.3 7.6 No No
6ARK_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 83.1 13.9 Yes Yes
2 empty 2.32 55.4 17.9 No No
3 empty 1.98 64.9 17.3 No No
4 empty 2.64 74.8 8.9 No No
5 empty 1.93 68.9 8.6 No No
6 empty 2.21 61.1 9.4 No No
7 empty 2.53 66.4 8.7 No No
8 empty 2.4 63.8 7.8 No No
9 empty 2.46 62.4 5.8 No No
10 empty 2.72 71.1 4.8 No No
6GJ5_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.54 76.1 23.6 Yes Yes
2 bound 2.4 67.6 28.5 No No
3 empty 2.47 61.2 18.6 No No
4 empty 1.97 58.3 17 No No
5 empty 2.45 58.5 15.2 No No
6 empty 2.09 60.2 9.5 No No
7 empty 2.9 48.6 7.7 No No
8 empty 1.92 70.7 6.1 No No
9 empty 2.76 67.8 5.6 No No
10 empty 2.67 54.5 7.7 No No
6E6F_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 72.7 26 Yes No
2 empty 1.92 61.7 18.9 No No
3 empty 2.43 68.4 15 No No
4 empty 2.33 62.8 14 No No
5 empty 2.63 64.3 8.6 No No
6 empty 2.2 76 0 No No
7 empty 2.8 57.4 7.8 No No
8 empty 2.43 51.1 10.1 No No
9 empty 2.68 63.7 10.2 No No
10 empty 2.56 68.2 5.6 No No
5WHA_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.97 74.4 20.2 Yes No
2 empty 2.7 65.4 22.5 No No
3 empty 2.33 55.9 13.5 No No
4 bound 1.74 66.2 11.6 No No
5 empty 2.33 63.2 13.7 No No
6 empty 1.91 65.9 7.7 No No
7 empty 2.36 75.2 8.2 No No
8 bound 1.99 73 9.2 No No
9 empty 2.52 59.2 7 No No
10 empty 2.81 59 11.3 No No
5WHD_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.61 62.9 22.9 No No
2 empty 2.32 63.1 14.5 No No
3 empty 2.23 61.6 16.5 No No
4 bound 1.24 72.2 8.1 No No
5 empty 1.88 60.4 8.4 No No
6 bound 1.73 73.2 5.4 No No
7 empty 2.6 57.5 9.4 No No
8 empty 3.05 65.5 9.9 No No
9 empty 2.3 56.5 7.3 No No
10 empty 2.74 62.8 6.7 No No
4EPX_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 65.1 31.4 Yes No
2 bound 2.06 76.4 15.6 No No
3 empty 2.22 67.8 17.3 No No
4 empty 2.62 60.2 15.2 No No
5 empty 2.24 60.2 11.5 No No
6 empty 1.99 59.7 8.7 No No
7 empty 2.75 59.1 10.1 No No
8 empty 1.76 60.2 8.5 No No
9 empty 2.49 47.1 9.1 No No
10 empty 2.27 53 6.8 No No
5WHB_G GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 74.1 28.9 Yes No
2 empty 2.52 67.1 18 No No
3 bound 1.89 70.2 13.1 No No
4 empty 2.42 66.6 15.2 No No
5 empty 2.37 59.2 20 No No
6 empty 2.29 61.6 8.4 No No
7 empty 2.51 64.2 6.5 No No
8 empty 2.29 65.4 9.7 No No
9 empty 2.26 60.7 7.9 No No
10 empty 2.94 58.4 9.7 No No
4M1S_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 62.5 20.3 No No
2 empty 2.67 65.1 18.6 No No
3 empty 2.14 63.7 14.3 No No
4 bound 1.62 74.2 9.3 No No
5 empty 2.17 65.6 8.4 No No
6 empty 1.76 73.8 9.3 No No
7 empty 2.36 56 8.7 No No
8 empty 2.11 68.6 6.9 No No
9 empty 1.54 72.2 6 No No
10 empty 1.87 58.3 6.8 No No
5VPY_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.3 71.4 23.9 Yes No
2 empty 2.54 68.2 19 No No
3 empty 1.85 66.2 13.7 No No
4 empty 2.38 60.7 13.5 No No
5 empty 2.98 57.2 10.9 No No
6 empty 2.31 70.5 11.1 No No
7 empty 2.33 46.6 9.3 No No
8 empty 2.92 60.6 7.1 No No
9 empty 1.93 67.3 7.8 No No
10 empty 2.69 59.1 7.1 No No
4M22_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 76.9 30.1 Yes No
2 empty 2.23 63.8 18.8 No No
3 empty 2.35 72.9 17.9 No No
4 empty 2.23 65.7 17.2 No No
5 empty 2.45 56.7 17.3 No No
6 empty 2.19 65.8 6.7 No No
7 empty 1.73 66.9 7.2 No No
8 empty 2.74 65.7 6.8 No No
9 empty 2.31 56.1 8.2 No No
10 empty 2.41 73.1 6.8 No No
4LPK_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 67.4 39.2 Yes No
2 empty 2.71 64.4 25.4 No No
3 empty 2.4 59.6 11.8 No No
4 empty 2.19 67.8 8.4 No No
5 empty 2.11 63.4 8.7 No No
6 empty 2.25 67 7.4 No No
7 empty 2.51 60.9 8.1 No No
8 empty 2.48 57.1 7.3 No No
9 empty 2.93 71.3 7.5 No No
10 empty 2.07 66.1 6.4 No No
6P8X_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 77.6 33 Yes Yes
2 empty 2.33 68 17.1 No No
3 empty 2.52 66.4 21.1 No No
4 empty 1.91 70.9 8.9 No No
5 empty 2.57 64.2 9 No No
6 empty 2.05 58.6 8.9 No No
7 empty 2 60.2 7.1 No No
8 empty 2.39 64.7 6.3 No No
9 empty 2.74 68.2 7 No No
10 empty 2.49 60.2 7.2 No No
4TQA_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.52 70.9 35.7 Yes Yes
2 empty 2.61 64.5 16 No No
3 empty 2.43 65.1 20.4 No No
4 empty 2.77 59.8 11.2 No No
5 empty 1.87 66.4 8.6 No No
6 empty 2.96 62.2 9 No No
7 empty 2.51 62.7 8.2 No No
8 empty 2.18 59.8 6.7 No No
9 empty 2.42 63.5 6.2 No No
10 empty 2.79 59 5.5 No No
6GOG_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 70.3 33.1 Yes Yes
2 empty 2.55 62.9 24.3 No No
3 empty 2.17 54.1 18.3 No No
4 empty 1.92 68.2 11.1 No No
5 empty 2.11 66.9 11.9 No No
6 empty 2.07 61.3 10.3 No No
7 empty 1.94 72.7 6.7 No No
8 empty 2.93 66.1 5.6 No No
9 empty 2.45 71.4 5.4 No No
10 empty 3.2 63.8 5 No No
5WHE_G GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 74.1 29.1 Yes Yes
2 empty 2.54 67 20.9 No No
3 empty 2.28 61.1 20.3 No No
4 bound 1.87 65.2 12.7 No No
5 bound 1.89 71.2 8.4 No No
6 empty 2.63 65.5 8.7 No No
7 empty 2.52 60.7 9 No No
8 empty 2.03 60 9.5 No No
9 empty 2.26 77.8 9.2 No No
10 empty 2.39 54.5 8.3 No No
4M1S_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 78.7 18.1 Yes Yes
2 empty 2.19 80.7 12.9 Yes Yes
3 empty 2.39 70.8 17.6 No No
4 bound 1.88 72.2 11.9 No No
5 empty 2.63 57.4 21.9 No No
6 empty 2.32 61.6 11.6 No No
7 empty 2.17 56.2 10.5 No No
8 empty 1.9 71.3 7.6 No No
9 empty 2.5 66.3 6.8 No No
10 empty 1.37 60 7.8 No No
4TQA_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 71.7 33.8 Yes Yes
2 empty 2.37 67.8 17.2 No No
3 empty 2.57 63 16.4 No No
4 empty 2.5 57 15.9 No No
5 empty 2.74 58.9 12.9 No No
6 empty 1.82 70 10.4 No No
7 empty 2.91 65.1 8.3 No No
8 empty 2.36 69.6 5.2 No No
9 empty 2.21 53.8 7.7 No No
10 empty 2.91 72.3 6.1 No No
6F76_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 69.6 36.4 Yes No
2 empty 2.75 65.9 19 No No
3 empty 2.33 46.9 16.6 No No
4 empty 2.18 69.8 13.6 No No
5 empty 2.27 62.1 15.1 No No
6 empty 2.13 57.5 10.9 No No
7 empty 2.15 58.8 10.5 No No
8 empty 2.43 59.4 11.8 No No
9 empty 2.85 67.9 5.7 No No
10 empty 1.43 70.3 6.5 No No
5OCT_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 61.7 25 Yes No
2 bound 2.15 85 16.7 Yes Yes
3 empty 2.47 59.5 14.7 No No
4 bound 2.15 65.7 13.8 No No
5 empty 2.06 44.7 15.1 No No
6 empty 2.42 70.4 10 No No
7 empty 1.96 68.5 9.8 No No
8 empty 2.21 53.6 9.2 No No
9 empty 2.37 60.5 8 No No
10 empty 1.95 54.3 8.2 No No
6FA3_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.59 71.8 33.3 Yes No
2 empty 2.12 50.1 19.3 No No
3 empty 2.79 66.5 18.8 No No
4 empty 1.98 66.9 18 No No
5 empty 2.3 63.1 14 No No
6 empty 2.05 71.9 6.1 No No
7 empty 2.67 65.9 7.3 No No
8 empty 2.3 63.5 7.1 No No
9 empty 2.55 47.7 10.4 No No
10 empty 2.91 64.2 5.8 No No
4EPT_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 74.1 32.9 Yes Yes
2 bound 2.32 72.3 10.7 No No
3 empty 2.5 69.1 17.3 No No
4 empty 2.78 66.3 11.4 No No
5 empty 2.16 67.8 9.6 No No
6 empty 1.98 60.7 8.1 No No
7 empty 2.51 69.9 6.5 No No
8 empty 2.5 52.2 11.2 No No
9 empty 2.47 57.7 8.3 No No
10 empty 2.48 60.4 9.9 No No
6GOM_D GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 70.4 23.4 No No
2 empty 2.72 62.3 24.7 No No
3 empty 2.45 52.5 20.7 No No
4 empty 1.91 67 18.4 No No
5 empty 2.18 69.1 10.6 No No
6 empty 2.23 62.6 11.7 No No
7 empty 2.85 58.8 11 No No
8 empty 2.3 59 9.1 No No
9 empty 2.02 60.3 8.5 No No
10 empty 1.69 70.1 5.7 No No
5TAR_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.05 64.2 23.3 No No
2 empty 2.26 70.6 17 No No
3 empty 2.13 63.6 17.9 No No
4 bound 1.72 72.6 12 No No
5 empty 1.79 60.2 13.7 No No
6 empty 2.38 64.5 15.4 No No
7 empty 2.24 58.4 15.8 No No
8 empty 2.58 62.8 9.2 No No
9 empty 2.38 45.3 12 No No
10 empty 2.49 55.7 14.6 No No
5USJ_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 75.5 23.8 Yes Yes
2 empty 2.5 66.4 32.4 No No
3 empty 2.57 50.8 22 No No
4 empty 2.79 65.8 18.1 No No
5 empty 2.16 71.1 11.1 No No
6 empty 2.51 50.2 13 No No
7 empty 2.03 69.2 6.7 No No
8 empty 2.08 69.9 8.5 No No
9 empty 2.55 71.7 5.6 No No
10 empty 2.04 69.6 8.2 No No
5UFQ_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 68.5 28 Yes No
2 empty 2.82 76.7 19.6 No No
3 empty 2.27 62.2 21.2 No No
4 empty 2.12 59.2 18.5 No No
5 empty 2.34 71.9 13.8 No No
6 empty 1.73 76.9 8.9 No No
7 empty 2.67 63 7.6 No No
8 empty 2.31 57.9 7.8 No No
9 empty 2.63 55.7 9.9 No No
10 empty 2.21 61.9 6.5 No No
6FA3_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 70.1 37.9 Yes No
2 empty 2.72 65.5 31.2 No No
3 empty 2.4 51.6 18.7 No No
4 bound 2.1 64.5 17.4 No No
5 empty 2.13 61.4 14.8 No No
6 empty 1.52 65.5 9.3 No No
7 empty 1.91 71.5 7 No No
8 empty 1.99 65.7 5.9 No No
9 empty 2.68 56 6.9 No No
10 empty 3.1 50 6.2 No No
4M1Y_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 68.8 22.1 Yes Yes
2 empty 2.3 64.7 15.1 No No
3 empty 2.41 72.9 10.5 No No
4 empty 2.58 78.7 12.9 No No
5 empty 2.3 61.9 10.4 No No
6 empty 2.09 66.5 9.8 No No
7 empty 1.98 73 7.8 No No
8 empty 1.81 60 13 No No
9 empty 2.75 61.7 6.6 No No
10 empty 2.08 64.5 6.3 No No
6OB3_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 77 24.4 Yes Yes
2 empty 2.31 67.6 15.6 No No
3 empty 2.53 71.7 12.7 No No
4 empty 2.52 69.5 11 No No
5 empty 2.2 71.9 10.2 No No
6 empty 2.63 66.8 8 No No
7 empty 2.1 70 11.5 No No
8 empty 2.18 64.3 7.7 No No
9 empty 2.51 67.3 8.4 No No
10 empty 2.81 60.4 5.9 No No
5VQ0_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 74.5 20.2 Yes No
2 empty 2.34 64.6 29 No No
3 empty 2.31 63.8 23.4 No No
4 empty 2.61 74.8 15.7 No No
5 empty 3.01 55.3 14.3 No No
6 empty 1.65 68.1 9 No No
7 empty 2.65 55.6 13.4 No No
8 empty 3 56.4 9.7 No No
9 empty 2.81 56.5 9.8 No No
10 empty 2.3 57.4 10.6 No No
5XCO_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 69.2 39.4 Yes Yes
2 empty 2.28 77 8.2 No No
3 empty 2.07 70.3 12.8 No No
4 empty 2.33 59.5 13.9 No No
5 empty 2.28 57.9 10.6 No No
6 empty 2.65 63.9 6.7 No No
7 empty 2.88 47.4 8.6 No No
8 empty 2.06 59.4 7.5 No No
9 empty 2.45 61.3 7.6 No No
10 bound 1.66 62.3 7.5 No No
4EPV_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 60.7 26.2 Yes No
2 bound 2.17 71.8 18.4 No No
3 empty 2.34 67.5 13.8 No No
4 empty 2.33 64.7 17.8 No No
5 empty 2.63 59.6 15 No No
6 empty 2.12 57.5 9.1 No No
7 empty 2.1 59.9 9.1 No No
8 empty 1.82 66.9 8.3 No No
9 empty 2.91 60.7 10.3 No No
10 empty 2.12 58 7.9 No No
6GQW_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.45 76.7 26.5 Yes Yes
2 empty 2.58 63.1 22.5 No No
3 empty 2.25 52.4 17.8 No No
4 bound 2.27 68.9 11.5 No No
5 empty 2.44 63.5 22.4 No No
6 empty 1.97 69.8 10.8 No No
7 empty 1.85 72.1 9.4 No No
8 empty 2.1 57.2 8.8 No No
9 empty 1.83 57.7 7.7 No No
10 empty 3.07 67.7 7 No No
6E6F_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 65 32.6 Yes No
2 empty 2.01 71.4 14.4 No No
3 empty 2.12 69.1 13.3 No No
4 empty 2.14 66.5 10.5 No No
5 empty 1.84 65.7 10.6 No No
6 empty 1.98 67.8 10 No No
7 empty 2.54 67.3 12.5 No No
8 empty 2 60.6 8.8 No No
9 empty 1.65 76.5 7.2 No No
10 empty 2.13 44.3 8.7 No No
5YXZ_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 76.9 40.5 Yes No
2 empty 2.31 63 22.5 No No
3 empty 2.15 67.2 14.5 No No
4 empty 2.26 66 9.3 No No
5 empty 2.23 59.8 13.1 No No
6 empty 2.12 74.4 8.3 No No
7 empty 2.67 59.4 12.8 No No
8 empty 2.04 66.2 7.3 No No
9 empty 2.33 57 7.1 No No
10 empty 2.29 65.3 6.6 No No
6F76_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 74 35.3 Yes No
2 empty 2.3 51.2 19.4 No No
3 empty 2.28 68 14.7 No No
4 empty 2.42 63.8 18.4 No No
5 bound 2.22 73.6 12.9 No No
6 empty 1.98 58.8 14 No No
7 empty 1.93 71.6 6.8 No No
8 empty 2.36 55.9 9.1 No No
9 empty 1.74 65.1 6.5 No No
10 empty 2.83 66.2 4.9 No No
4M1W_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 71.5 37.9 Yes No
2 empty 2.61 63.6 17.9 No No
3 empty 2.27 66.9 11.6 No No
4 empty 2.03 73.9 7.8 No No
5 empty 2.36 55.7 11.6 No No
6 empty 2.52 66.1 7 No No
7 empty 2.03 76.9 7.3 No No
8 empty 1.98 59.9 8.2 No No
9 empty 2.44 58.7 9.4 No No
10 empty 1.63 71.6 6.5 No No
4QL3_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.36 67.8 30.8 Yes Yes
2 bound 2.21 72.4 18.3 No No
3 empty 2.43 63.8 20.3 No No
4 empty 2.17 61.3 15.1 No No
5 empty 2.78 61.5 13.3 No No
6 empty 1.93 66.5 11.5 No No
7 empty 2.28 55.7 13.1 No No
8 empty 3.08 63.8 10.4 No No
9 empty 2.37 52.6 8.4 No No
10 empty 3.35 77.1 7 No No
4LYF_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 72.8 23.2 Yes No
2 empty 2.32 69.1 15.2 No No
3 empty 2.21 66.8 11.9 No No
4 empty 1.96 67.1 11.3 No No
5 empty 2.49 56.7 9.8 No No
6 empty 1.96 56.3 10.3 No No
7 empty 2.54 64.7 6.6 No No
8 empty 2.71 57.4 8.3 No No
9 empty 2.46 52.5 10 No No
10 empty 2.29 66.9 8.4 No No
5VQ6_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 69.1 22.5 No No
2 empty 2.51 63.1 20.1 No No
3 empty 1.94 64.2 12.8 No No
4 empty 2.41 73.3 16.2 No No
5 empty 1.87 55.9 10.2 No No
6 empty 2.21 68.1 8.2 No No
7 empty 2.57 54.1 8.7 No No
8 empty 2.86 62.4 9.9 No No
9 empty 1.9 75.6 6.2 No No
10 empty 2.46 67.4 6.5 No No
6FA2_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.45 75 23.8 Yes Yes
2 bound 2.18 66.1 28 No No
3 empty 2.62 64.2 25.3 No No
4 empty 2.46 51.9 16.9 No No
5 empty 2.28 58.6 12.2 No No
6 empty 2.07 69.9 10 No No
7 empty 1.84 57 9.1 No No
8 empty 2.25 57.2 9.6 No No
9 empty 1.85 57.4 5.7 No No
10 empty 2.2 58.3 7 No No
5WHA_D GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 65.1 19.2 No No
2 empty 2.4 64.5 17.6 No No
3 empty 2.59 69.3 17.9 No No
4 empty 2.38 65.6 12.7 No No
5 empty 2.23 70.8 13 No No
6 empty 2.35 66.5 8.7 No No
7 bound 1.14 73.3 10.8 No No
8 empty 2.39 41.8 9 No No
9 bound 2.02 72.1 8.7 No No
10 empty 2.32 66.9 7.3 No No
4Q01_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 82.3 13.4 Yes Yes
2 empty 2.64 62.9 28.8 No No
3 bound 2.27 71.7 16.5 No No
4 empty 2.23 65.4 17.3 No No
5 empty 2.11 62.2 15.9 No No
6 empty 2.11 71.2 9 No No
7 empty 2 97.2 0 Yes No
8 empty 2.52 83.2 7.2 No No
9 empty 2.71 66.9 8.6 No No
10 empty 3.14 61.3 7.4 No No
5OCT_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 72.4 26.2 Yes Yes
2 empty 2.79 63.1 28 No No
3 empty 2.31 53 15.5 No No
4 bound 1.89 69.5 10.3 No No
5 empty 1.94 59.3 10.8 No No
6 empty 2.32 66.8 11.1 No No
7 bound 2.49 60.6 15.1 No No
8 empty 1.99 68.1 11.6 No No
9 empty 2.08 63.9 11.7 No No
10 empty 2.87 62.4 10 No No
4LV6_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 78.8 34.2 Yes Yes
2 empty 2.39 66.3 17.4 No No
3 empty 2.78 68.1 14.8 No No
4 empty 2.2 75.5 10.5 No No
5 empty 2.11 71.3 7.5 No No
6 empty 2.7 75.1 7.9 No No
7 empty 2.02 68.8 7.4 No No
8 empty 2 68.9 5.4 No No
9 empty 2.06 65.6 5.9 No No
10 empty 3.09 52.7 8.6 No No
4LDJ_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.5 67.2 28.4 Yes Yes
2 bound 2.13 75.8 19.5 No No
3 empty 2.53 62.8 23.8 No No
4 empty 2.19 57.2 14.5 No No
5 empty 1.86 68.6 10.7 No No
6 empty 2.55 55.1 8.2 No No
7 empty 2.31 58.2 6.2 No No
8 empty 2.38 58.2 6.1 No No
9 empty 2.06 66.2 6.1 No No
10 empty 1.94 53.5 6.2 No No
5VPI_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.27 77.8 23.2 Yes No
2 empty 2.34 67.3 18.3 No No
3 empty 2.09 66.6 14.4 No No
4 empty 2.36 70.5 9.5 No No
5 empty 1.88 59.7 11.3 No No
6 empty 2.51 59.9 12.2 No No
7 empty 2.8 55.2 10.5 No No
8 empty 2.36 69.8 7.8 No No
9 empty 2.66 57 7.9 No No
10 empty 2.62 64.4 7.1 No No
4LYH_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 71.2 29.7 Yes No
2 empty 2.38 60.3 25.9 No No
3 empty 2.47 69.6 14 No No
4 empty 2.17 63.5 9.6 No No
5 empty 2.05 74.6 7.5 No No
6 empty 2.13 64.7 8.9 No No
7 empty 1.88 55.4 8.7 No No
8 empty 2.77 63.6 5.8 No No
9 empty 3.02 67.3 5.2 No No
10 empty 2.4 58.1 8.2 No No
4DSN_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 82.1 12.3 Yes Yes
2 empty 2.13 53.6 20.1 No No
3 empty 2.3 66.4 16.4 No No
4 empty 2.19 69.1 19.3 No No
5 empty 1.92 52.1 16.5 No No
6 empty 2.22 64.5 10.7 No No
7 empty 2.18 65.6 11.7 No No
8 empty 2.24 65.6 9.3 No No
9 empty 2.1 51.5 9 No No
10 empty 2.61 59.1 7.4 No No
6F76_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 68.9 37.7 Yes Yes
2 empty 2.56 62.4 18.8 No No
3 empty 2.26 51.4 18.9 No No
4 bound 2.16 72.9 14.5 No No
5 empty 2.12 63.2 13.8 No No
6 empty 1.99 70.8 6.8 No No
7 empty 2.14 65.8 11.1 No No
8 empty 2.43 56.2 7.3 No No
9 empty 1.61 71.2 6.9 No No
10 empty 3.24 74 6.5 No No
6P8X_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 76.2 38 Yes Yes
2 empty 2.43 66.1 20.7 No No
3 empty 2.42 68.1 18 No No
4 empty 2.33 63.3 14.2 No No
5 empty 2.24 64 14 No No
6 empty 2.28 80.2 5.7 No No
7 empty 2.42 70.2 6.5 No No
8 empty 2.58 64.8 8.2 No No
9 empty 3.11 65.3 0 No No
10 empty 2.5 57.9 8.6 No No
6GOG_E GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 71 34.1 Yes Yes
2 empty 2.31 52.9 19 No No
3 empty 2.37 68.6 14.6 No No
4 empty 2.28 60.6 16 No No
5 empty 2.15 73.2 6.1 No No
6 empty 1.88 66.9 6.6 No No
7 empty 2.46 57.8 6.7 No No
8 empty 1.92 59.6 7.9 No No
9 empty 2.19 47.6 6.2 No No
10 empty 2.09 56.3 6.2 No No
5MLA_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 74.1 23.8 Yes Yes
2 empty 2.75 62.1 20.8 No No
3 empty 2.56 62.3 14 No No
4 empty 2.44 65.9 14.5 No No
5 empty 2.16 71.5 11.5 No No
6 empty 2.06 76.8 10.6 No No
7 empty 2.16 60.9 11.2 No No
8 empty 2.88 64.4 7.6 No No
9 empty 2.22 51.6 8.7 No No
10 empty 2.42 57.1 8 No No
5UK9_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 70.6 34.4 Yes No
2 empty 2.54 67.8 17.7 No No
3 empty 2.02 64.5 12.4 No No
4 empty 2.26 64.9 16 No No
5 empty 2.48 58.4 17 No No
6 empty 2.93 63.3 9.9 No No
7 empty 2.42 47.3 11 No No
8 bound 2.74 73.1 8.3 No No
9 empty 2.7 70.3 7.6 No No
10 empty 2.7 61.6 8.4 No No
5MLB_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 61.3 32 Yes No
2 bound 1.94 76.2 19.6 No No
3 empty 2.28 63.7 17.5 No No
4 empty 2.39 61.8 10.8 No No
5 empty 2.6 57.2 12.2 No No
6 empty 2 61.8 8.5 No No
7 empty 2.74 61.4 10.2 No No
8 empty 2.04 70.5 6.1 No No
9 empty 2.61 62.1 7.1 No No
10 empty 2.6 66 8.8 No No
6GQT_F GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 67.4 24.2 Yes No
2 empty 2.59 64.4 24.1 No No
3 empty 2.4 54.1 18.7 No No
4 empty 2.05 63.9 21.6 No No
5 bound 1.89 70 14.1 No No
6 empty 2.28 70.4 9.5 No No
7 empty 2.49 65.8 9.1 No No
8 empty 1.98 63.8 11.4 No No
9 empty 2.06 64 6.5 No No
10 empty 1.56 71.3 8.1 No No
6P8Y_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 69.4 36 Yes Yes
2 empty 2.48 65.4 21.5 No No
3 empty 2.06 60.5 14.7 No No
4 empty 1.97 60.9 10 No No
5 empty 1.9 74.1 7.8 No No
6 empty 2.52 57.9 11.8 No No
7 empty 2.26 55 8.4 No No
8 empty 3.09 63.1 5.9 No No
9 empty 2.37 50 8.3 No No
10 empty 2.17 69.5 6.2 No No
6GOM_F GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 70.8 23.3 No No
2 empty 2.29 67.1 21.9 No No
3 empty 2.37 66.3 12.7 No No
4 empty 2.2 52.3 14.9 No No
5 empty 2.27 65 12.3 No No
6 empty 1.94 71.8 8.1 No No
7 empty 2.23 59.3 11 No No
8 empty 2.33 56.4 7.1 No No
9 empty 2.89 76.9 6.8 No No
10 empty 2.03 67.7 6 No No
6GQT_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 70 25.5 Yes No
2 empty 2.59 62.7 26.6 No No
3 empty 2.49 49.8 19.2 No No
4 empty 2 66.7 18.7 No No
5 bound 2.02 75.8 9.8 No No
6 empty 1.83 71.4 9 No No
7 empty 1.93 68.1 8.2 No No
8 empty 1.74 62.5 6.1 No No
9 empty 2.15 60 7.2 No No
10 empty 2.16 56.7 7 No No
5V71_F GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 66.8 22.2 No No
2 bound 1.99 77.7 17.5 No No
3 empty 2.35 65.5 18.2 No No
4 empty 2.48 62.1 14.1 No No
5 empty 2.33 56.7 14 No No
6 empty 1.96 69.4 12 No No
7 empty 2.44 64 11.4 No No
8 empty 2.21 66.7 11.6 No No
9 empty 2.52 60.1 11.4 No No
10 empty 3.02 61.9 8 No No
6GOG_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 84.5 19.4 Yes Yes
2 bound 2.24 63.1 23.7 No No
3 empty 2.16 63.2 14.2 No No
4 empty 2.46 61.7 12.4 No No
5 empty 2.33 47.1 17.3 No No
6 empty 2 69.1 12.3 No No
7 empty 2.09 52.4 10.2 No No
8 empty 2.37 67.6 9 No No
9 empty 2.23 54.7 10.2 No No
10 empty 2.02 54 8.3 No No
6GJ6_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.39 72.1 30.1 Yes No
2 bound 2.18 69.6 20.9 No No
3 empty 2.34 66.1 16.6 No No
4 empty 2.53 61.7 12.8 No No
5 empty 2.15 68.5 10.3 No No
6 empty 2.26 60.5 8.1 No No
7 empty 2.8 59.9 6.6 No No
8 empty 2.62 59.4 7.3 No No
9 empty 2.29 59.8 8.9 No No
10 empty 1.54 72.3 5.1 No No
6P0Z_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 71.2 32.9 Yes No
2 empty 2.08 70.4 17.1 No No
3 empty 2.53 59.1 24.3 No No
4 empty 2.01 62.2 16.4 No No
5 empty 2.74 62.8 12.4 No No
6 empty 2.05 67.9 11.8 No No
7 empty 2.4 64.1 9.3 No No
8 empty 2.16 72.1 5 No No
9 empty 2.79 54.4 10.8 No No
10 empty 2.59 60.1 9.6 No No
5VQ1_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.53 67.3 44 Yes No
2 empty 2.08 66.2 12.7 No No
3 empty 2.78 71 16.4 No No
4 empty 2.25 61.1 17.9 No No
5 empty 2.37 57.5 12.8 No No
6 empty 1.61 68.3 10.6 No No
7 empty 2.16 59.7 12.1 No No
8 empty 2.97 60.2 9.9 No No
9 empty 2.1 60.2 8.5 No No
10 empty 2.72 57.1 6.5 No No
5V9L_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 64.5 26.2 Yes No
2 bound 1.96 78.5 13.2 No No
3 empty 2.71 62 27 No No
4 empty 2.35 62.8 12.8 No No
5 empty 2.5 72.5 11.4 No No
6 empty 1.78 72.3 7.9 No No
7 empty 2.15 55.2 11.9 No No
8 empty 2.83 67.5 6.1 No No
9 empty 2.46 81 8.1 No No
10 empty 1.46 65.5 7.9 No No
6QUU_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 76.7 22.5 Yes Yes
2 empty 2.09 67.9 16 No No
3 empty 2.02 71.7 13.6 No No
4 empty 2.53 75.4 9.7 No No
5 empty 2.17 70.9 8.3 No No
6 empty 2.24 66.7 8.8 No No
7 empty 2.44 66.7 8.9 No No
8 empty 2.38 62.4 8.5 No No
9 empty 2.93 53.9 9.9 No No
10 empty 2.3 49.7 9.7 No No
5VQ2_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 65.3 33 Yes No
2 empty 2.08 64 13.6 No No
3 empty 2.28 59.4 15.8 No No
4 empty 2.63 71.9 14.9 No No
5 empty 2.55 56.7 19 No No
6 empty 2.39 62.5 10.2 No No
7 empty 2.15 76.8 8.3 No No
8 empty 1.79 72.5 8.4 No No
9 empty 2.96 62 5.1 No No
10 empty 3.22 64.5 5.8 No No
5KYK_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 67.3 37.4 Yes Yes
2 empty 2.06 64.9 17 No No
3 empty 2.3 66.1 18.2 No No
4 empty 2.35 57.5 13.8 No No
5 empty 2.73 61.5 11.1 No No
6 empty 2.93 61.3 13.4 No No
7 empty 2.53 56.7 10.7 No No
8 empty 2.23 58.5 12.1 No No
9 empty 2.47 63.5 8.6 No No
10 empty 2.3 66 7.4 No No
6GOM_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 76.1 20.3 Yes No
2 empty 2.43 51 19.2 No No
3 empty 2.53 66.2 18.3 No No
4 empty 1.89 62.2 12.4 No No
5 empty 2.32 65.2 17 No No
6 empty 2.16 71.6 9.7 No No
7 empty 2.13 68.1 7.6 No No
8 empty 2.58 56 10.3 No No
9 empty 2.24 59.6 7.9 No No
10 empty 1.64 65.4 7.8 No No
6CCH_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 72.9 30.6 Yes Yes
2 empty 2.35 65.3 22.9 No No
3 empty 2.22 59.9 20.9 No No
4 empty 2.08 77.5 11.6 No No
5 empty 2.19 60 16.2 No No
6 empty 2.03 73.4 11.3 No No
7 empty 2.06 50.8 9.7 No No
8 empty 2.09 71.5 9.4 No No
9 empty 1.75 73.4 8.2 No No
10 empty 2.29 62.7 8.4 No No
6QUX_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 79.8 22.1 Yes Yes
2 empty 2.19 69 12.7 No No
3 empty 1.92 67.8 8.4 No No
4 empty 2.38 67.2 11.2 No No
5 empty 2.56 64.5 18.8 No No
6 empty 2.15 75.3 11 No No
7 empty 2.46 65.2 11.4 No No
8 empty 2.46 61.2 11.9 No No
9 empty 3.11 67.5 7.7 No No
10 empty 2.47 69 7.2 No No
5OCO_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.3 72.4 30.1 Yes No
2 empty 2.42 52.2 20.1 No No
3 empty 2.3 65.8 14.2 No No
4 empty 2.47 66.2 17.6 No No
5 bound 2.1 73.1 10.5 No No
6 empty 2.04 71.3 10 No No
7 empty 2.44 56.4 11 No No
8 empty 2.84 61.8 8.2 No No
9 empty 3.01 66.3 11 No No
10 empty 2.75 70 5.9 No No
6FA4_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 80.5 21 Yes Yes
2 empty 2.31 62.1 17.9 No No
3 empty 2.21 51.9 19.1 No No
4 bound 1.95 68.6 16 No No
5 empty 2 56.9 15.4 No No
6 empty 2.28 57 11.7 No No
7 empty 2.2 55.8 12.1 No No
8 empty 2.27 72.6 8.7 No No
9 empty 2.16 52.7 9.7 No No
10 empty 2.02 58.3 9.2 No No
6GQX_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 71.4 37.7 Yes No
2 empty 2.43 63.3 20.6 No No
3 empty 2.41 50.6 17.8 No No
4 bound 2.07 68.7 13.3 No No
5 empty 2.11 74.5 7.8 No No
6 empty 2.36 62.1 14.5 No No
7 empty 1.99 71.2 9.9 No No
8 empty 2.88 58.3 11.2 No No
9 empty 2.12 66.1 5.3 No No
10 empty 2.23 58.5 7.6 No No
5WHB_J GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.48 71.4 30.5 Yes Yes
2 empty 2.4 67.8 20 No No
3 empty 2.3 66.7 9.3 No No
4 bound 1.64 73.2 9.3 No No
5 empty 2.82 62.7 13.4 No No
6 empty 2.42 71.9 8.7 No No
7 empty 2.32 61.3 14.1 No No
8 bound 1.93 72.1 8.1 No No
9 empty 2.5 70.5 10.9 No No
10 empty 2.82 78.2 7 No No
3GFT_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 73.4 23.1 Yes Yes
2 empty 2.28 68.9 23 No No
3 empty 2.5 64 18.9 No No
4 empty 2.55 54.7 17.8 No No
5 empty 2.18 56.7 10.3 No No
6 empty 2.08 73.3 7 No No
7 empty 2.05 52.8 9.9 No No
8 empty 2.32 63.7 7.9 No No
9 empty 2.42 57.7 8 No No
10 empty 3.02 57.9 9.1 No No
6FA3_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 70.7 31.3 Yes Yes
2 empty 2.34 55.8 25.8 No No
3 empty 2.73 66.9 17.7 No No
4 bound 2.22 72.9 12 No No
5 empty 1.96 73.4 6.8 No No
6 empty 2.36 55.7 9.3 No No
7 empty 2.9 72.7 5.3 No No
8 empty 2.77 52.4 9.1 No No
9 empty 1.39 71 5.9 No No
10 empty 2.19 60.8 5.3 No No
6GQY_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 78 22.2 Yes Yes
2 empty 2.73 62.7 25.7 No No
3 empty 2.58 54.4 18.8 No No
4 bound 2.33 68 18.8 No No
5 empty 2.31 63.6 13.6 No No
6 empty 2.14 59.5 8.6 No No
7 empty 1.97 70 10.7 No No
8 empty 2.19 62.6 9.5 No No
9 empty 2.82 61.9 10.2 No No
10 empty 1.98 57.4 7.1 No No
5VPZ_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 71.3 25.8 Yes No
2 empty 1.88 67.1 15 No No
3 empty 2.33 68.7 12.6 No No
4 empty 2.6 71.1 18 No No
5 empty 2.54 52.8 9.1 No No
6 empty 2.54 53.2 10.6 No No
7 empty 3.08 62.5 12.8 No No
8 empty 2.66 62 6.6 No No
9 empty 2.18 61 8 No No
10 empty 2.81 59.4 7.7 No No
4EPR_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 81.4 12.6 Yes Yes
2 empty 2.39 67.5 17.1 No No
3 empty 2.09 63.1 13.3 No No
4 empty 2.31 76.5 10.9 No No
5 empty 2.37 60.5 17.7 No No
6 empty 2.45 75.9 10.5 No No
7 empty 2.19 63.7 11.3 No No
8 empty 2.55 64.4 11.1 No No
9 empty 1.68 67.9 12.1 No No
10 empty 2.5 68.3 6.6 No No
4OBE_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 71.1 33.2 Yes Yes
2 empty 2.27 66.2 14.7 No No
3 empty 2.16 69.7 12.2 No No
4 empty 2.61 57 16.1 No No
5 empty 1.88 70.7 10.7 No No
6 empty 2.91 65.7 8.3 No No
7 empty 2.91 54.4 6.3 No No
8 empty 2.25 65 5.2 No No
9 empty 2.43 48.5 6.6 No No
10 empty 2.18 67.3 5.1 No No
6MBT_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 71.7 37.2 Yes No
2 empty 2.33 72.2 15.2 No No
3 empty 2.68 63.8 19.3 No No
4 empty 2.28 63.5 19.5 No No
5 empty 2.71 58.9 12.1 No No
6 empty 2 71.2 7.4 No No
7 empty 2.84 60.7 9.9 No No
8 empty 2.2 64.4 8.6 No No
9 empty 2.43 65.4 5.8 No No
10 empty 2.52 62.1 6.5 No No
5VPY_A GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.29 69.6 21.3 No No
2 empty 2.71 70.6 18.3 No No
3 empty 1.81 64.1 9.8 No No
4 empty 2.91 58.8 13.3 No No
5 empty 2.42 57.9 15.4 No No
6 empty 2.53 55.9 11.5 No No
7 empty 2.16 60.8 7.6 No No
8 empty 2.86 59.5 7.4 No No
9 empty 2.58 65.2 9.3 No No
10 empty 1.68 69.9 6.6 No No
6GJ5_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.58 70.6 35.5 Yes Yes
2 empty 2.38 60.9 27.1 No No
3 bound 2.05 76.5 9.5 No No
4 empty 2.28 75.4 11.6 No No
5 empty 1.93 69.5 10 No No
6 empty 2.56 65.4 9 No No
7 empty 2.61 57.6 12.7 No No
8 empty 2.78 64.3 6.6 No No
9 empty 2.94 62.5 6.6 No No
10 empty 2.33 72.9 5.1 No No
4NMM_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.35 66.8 29.6 Yes Yes
2 bound 2.11 73.1 18.3 No No
3 empty 2.43 67.6 17 No No
4 empty 2.16 58.1 15.2 No No
5 empty 2.65 58.9 15 No No
6 empty 1.84 67.4 11 No No
7 empty 2.11 62.7 7.8 No No
8 empty 2.37 58.1 12.1 No No
9 empty 3.1 68.6 9.9 No No
10 empty 2.32 63.9 7.6 No No
4LRW_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 75.8 31.5 Yes No
2 empty 2.53 71 14.8 No No
3 empty 2.34 67.7 13.6 No No
4 empty 2.12 72.9 7.1 No No
5 empty 2.05 61.5 11.8 No No
6 empty 2.48 70.9 11.5 No No
7 empty 2.95 51.8 8 No No
8 empty 2.44 65.1 8.4 No No
9 empty 2.65 64.1 6.2 No No
10 empty 2.9 64.9 8.3 No No
5UFE_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.63 72.6 30.5 Yes No
2 empty 2.41 66.8 22.9 No No
3 empty 2.46 78.5 13.2 No No
4 empty 2.37 61.5 17 No No
5 empty 2.05 74.6 9.6 No No
6 empty 2.17 57.7 12.3 No No
7 empty 2.16 59.9 8.9 No No
8 empty 1.47 66.4 5.6 No No
9 empty 2.53 65.2 0 No No
10 empty 2.08 50.9 9.1 No No
5O2S_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 80.9 12 Yes Yes
2 empty 2.25 68.2 14.3 No No
3 empty 2.39 66.7 18.4 No No
4 empty 2.6 56.8 27.9 No No
5 empty 2.49 55.9 10.7 No No
6 empty 2.04 69.4 8.9 No No
7 empty 2.32 57.1 7.8 No No
8 empty 2.39 57.6 8.4 No No
9 empty 2.55 51.6 7.4 No No
10 empty 1.43 72.5 5.4 No No
5USJ_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 73 23.7 Yes Yes
2 empty 2.38 64.5 20.5 No No
3 empty 2.41 49.6 20.7 No No
4 empty 2.61 63.1 21.5 No No
5 empty 2.02 71.8 11 No No
6 empty 3 66 7.1 No No
7 empty 2.5 58.4 8.3 No No
8 empty 2.44 55.1 9.3 No No
9 empty 2.23 64.5 7.6 No No
10 empty 2.09 62.4 8.8 No No
5MLB_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 80.9 12 Yes Yes
2 empty 2.25 68.2 14.3 No No
3 empty 2.39 66.7 18.4 No No
4 empty 2.6 56.8 27.9 No No
5 empty 2.49 55.9 10.7 No No
6 empty 2.04 69.4 8.9 No No
7 empty 2.32 57.1 7.8 No No
8 empty 2.39 57.6 8.4 No No
9 empty 2.55 51.6 7.4 No No
10 empty 1.43 72.5 5.4 No No
6CCX_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 60.7 34.6 Yes No
2 bound 2.15 75.1 26.1 No No
3 empty 2.49 69 22.1 No No
4 bound 2 63.5 17.4 No No
5 empty 2.43 68.8 14.3 No No
6 bound 2.33 76.8 10.4 No No
7 bound 2.79 56.4 14.3 No No
8 empty 2.01 61.3 13.1 No No
9 empty 2.17 50.5 15.2 No No
10 empty 2.41 47.6 8.4 No No
6FA2_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 75.1 33.4 Yes No
2 empty 2.11 66.5 23.8 No No
3 empty 2.65 63.2 22.5 No No
4 bound 2.3 66.9 15.9 No No
5 empty 2.31 70.8 11.1 No No
6 empty 1.63 69.6 8.9 No No
7 empty 2.23 63.4 5.8 No No
8 empty 2.27 64 10.1 No No
9 empty 2.84 62.7 5.9 No No
10 empty 2.21 57.7 7.3 No No
5V9U_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 80.9 19.7 Yes Yes
2 bound 2.05 77.8 20 No No
3 empty 2.29 70.7 16.9 No No
4 empty 2.2 61.9 11.6 No No
5 empty 2.5 72.9 8 No No
6 empty 2.05 68.6 8.7 No No
7 empty 2.24 59.7 9.6 No No
8 empty 1.89 50 11 No No
9 empty 2.1 59.9 9.9 No No
10 empty 2.2 61.9 12.7 No No
6GJ8_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.55 78.4 22.7 Yes No
2 empty 2.27 67.8 17.4 No No
3 empty 2.58 64.4 16.5 No No
4 empty 2.72 63.2 13.4 No No
5 bound 2.1 73.8 9.1 No No
6 empty 2.52 61.2 16.3 No No
7 empty 2.77 55.8 13.6 No No
8 empty 2.52 61.4 11.9 No No
9 empty 1.96 69.6 7.8 No No
10 empty 2.72 65.3 11.4 No No
5UQW_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 72.4 20.3 Yes No
2 empty 2.24 63.6 21.1 No No
3 empty 2.31 67.4 18.1 No No
4 empty 2.12 73.6 10.6 No No
5 empty 2.43 59.1 10.8 No No
6 empty 1.69 68 8.1 No No
7 empty 1.41 61.3 8.7 No No
8 empty 2.15 62.7 6.8 No No
9 empty 2.2 65.1 6.8 No No
10 empty 2.51 56 11.5 No No
5O2S_E GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 68.5 23 No No
2 bound 2.05 79.6 19 Yes Yes
3 empty 2.44 66.4 19.1 No No
4 empty 2.08 60.6 10.8 No No
5 empty 2.41 54.4 21.7 No No
6 empty 2.05 62.4 9.8 No No
7 empty 2.35 68 6.9 No No
8 empty 2.37 65.6 8.6 No No
9 empty 2.93 60.8 7.5 No No
10 empty 2.88 55.8 8.3 No No
6GQT_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 73.7 26.1 Yes No
2 empty 2.85 66.7 18.8 No No
3 empty 2.3 67.5 18 No No
4 empty 2.6 53.1 12.8 No No
5 empty 1.98 72.9 8.6 No No
6 empty 1.53 69 11.3 No No
7 empty 2.4 59.2 13.3 No No
8 empty 2.24 61.9 11.8 No No
9 empty 2.31 58.3 6.6 No No
10 empty 2.24 67.8 5.9 No No
6FA1_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.48 70.1 34.9 Yes No
2 empty 2.29 55.2 26.7 No No
3 empty 2.65 63.4 24.5 No No
4 empty 1.89 73.9 9.8 No No
5 empty 2.04 73.5 9.8 No No
6 empty 2.89 66 12.4 No No
7 empty 2.3 57.7 7.9 No No
8 empty 1.98 65.5 7.6 No No
9 empty 3.03 67.9 6.1 No No
10 empty 2.98 60.4 6 No No
6P8X_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 78 31.4 Yes Yes
2 empty 2.38 67 16.8 No No
3 empty 2.44 64.5 15 No No
4 empty 2.25 68.6 9.8 No No
5 empty 2.54 63.1 10.9 No No
6 empty 2.07 60.6 7.7 No No
7 empty 2.75 67.2 10.3 No No
8 empty 2.04 57.8 8.2 No No
9 empty 2.04 66.7 7.7 No No
10 empty 2.44 66.9 9.4 No No
5MLB_E GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 68.5 23 No No
2 bound 2.05 79.6 19 Yes Yes
3 empty 2.44 66.4 19.1 No No
4 empty 2.08 60.6 10.8 No No
5 empty 2.41 54.4 21.7 No No
6 empty 2.05 62.4 9.8 No No
7 empty 2.35 68 6.9 No No
8 empty 2.37 65.6 8.6 No No
9 empty 2.93 60.8 7.5 No No
10 empty 2.88 55.8 8.3 No No
6MQN_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 55.8 24.1 Yes No
2 empty 2.55 67.2 17.4 No No
3 bound 2.37 66.6 10.6 No No
4 empty 2.33 64.6 16.2 No No
5 empty 2.37 66.1 15.8 No No
6 bound 1.8 72.1 13.1 No No
7 empty 2.12 69.2 11.3 No No
8 empty 2.49 58.7 9.9 No No
9 empty 2.28 51.5 7.8 No No
10 empty 1.45 69.4 5.9 No No
6B0V_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.39 76.6 33.9 Yes Yes
2 empty 2.51 69.3 15.6 No No
3 empty 2.01 64.6 14 No No
4 empty 2.07 59.8 11.1 No No
5 empty 2.36 67.5 7.7 No No
6 empty 1.97 54.2 9.4 No No
7 empty 2.82 59.7 6.3 No No
8 empty 2.3 64.8 5.6 No No
9 empty 2.27 59 5.2 No No
10 empty 2.07 68.4 7.3 No No
5TB5_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 63.8 21.4 No No
2 empty 2.45 65.4 24 No No
3 empty 1.81 62.9 18.8 No No
4 empty 1.9 64.9 12.2 No No
5 empty 2.24 76.8 11.5 No No
6 empty 2.19 46.4 15.4 No No
7 bound 2.25 60.7 17.7 No No
8 empty 2.18 70.7 11.6 No No
9 empty 2.82 66.9 11.1 No No
10 empty 2.56 71.2 10.1 No No
4M1W_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 74.1 20 Yes Yes
2 empty 2.63 62.6 27.5 No No
3 bound 1.91 70.1 12.9 No No
4 empty 2.41 80.9 12.3 No No
5 empty 2.26 63.2 11 No No
6 empty 2.12 71.7 7.5 No No
7 empty 1.33 69.2 6.6 No No
8 empty 2.37 62.3 6 No No
9 empty 2.27 59.6 5.4 No No
10 empty 2.44 64.3 6.6 No No
6FA3_F GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.41 68.9 33.4 Yes Yes
2 empty 2.3 52 18.8 No No
3 bound 2.14 72.9 14.2 No No
4 empty 2.54 70.1 17.7 No No
5 empty 2.49 60.1 16.6 No No
6 empty 1.68 71.6 6.6 No No
7 empty 2.24 66.3 8.6 No No
8 bound 2.53 70.2 7.9 No No
9 empty 2.95 66.5 6.8 No No
10 empty 2.09 61.1 5.9 No No
5WHA_G GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.35 70.4 33 Yes Yes
2 empty 2.61 67.7 19.2 No No
3 bound 2.54 72.9 25.9 No No
4 empty 2.36 68.1 8.3 No No
5 bound 2.01 77.9 9.3 No No
6 empty 2.62 49.6 12.5 No No
7 empty 2.21 55.7 10.7 No No
8 empty 2.51 61.3 10.9 No No
9 empty 3.19 49.2 7.6 No No
10 empty 2.37 61 7 No No
4TQ9_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 66.9 28.7 Yes Yes
2 bound 2.19 80.2 14.5 Yes Yes
3 empty 2.49 59.7 19.8 No No
4 empty 2.46 70.5 17.2 No No
5 empty 2.45 55 15.4 No No
6 empty 2.71 58 12.9 No No
7 empty 1.97 67.7 8.9 No No
8 empty 2.93 52 11 No No
9 empty 2.91 61.5 8.1 No No
10 empty 2.18 74.2 6.3 No No
4Q01_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 79.6 17.7 Yes Yes
2 empty 2.33 71.7 18.7 No No
3 bound 2.23 70.4 16.8 No No
4 empty 2.21 60.1 13.1 No No
5 empty 2.07 73.9 14.6 No No
6 empty 2.13 71.1 12 No No
7 empty 2.61 73.9 11.5 No No
8 empty 2.14 66.9 13.5 No No
9 empty 2.33 66.4 13 No No
10 empty 2.69 65.3 5.3 No No
6H47_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.47 62.8 29.7 Yes No
2 empty 2.22 70.8 13.6 No No
3 empty 1.99 61.6 19.6 No No
4 empty 2.1 66 13.7 No No
5 empty 2.19 66 13.7 No No
6 empty 2.71 68.6 16.4 No No
7 empty 2.31 55.1 13.1 No No
8 empty 1.58 72.3 8.3 No No
9 empty 2.99 78 0 No No
10 empty 2.86 58.8 9.8 No No
5WHE_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 65.3 30.6 Yes No
2 bound 2.07 71.1 27 No No
3 empty 2.62 66.2 22.6 No No
4 empty 2.37 66.1 18 No No
5 empty 2.26 65.8 13.2 No No
6 empty 2.43 46.8 11.4 No No
7 empty 2.65 69.7 9.9 No No
8 empty 2.46 66.2 6.4 No No
9 empty 3.41 70.1 5.4 No No
10 empty 1.55 71.4 5.9 No No
4M1Y_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 73.7 28.5 Yes No
2 empty 2.55 65 18.4 No No
3 empty 2.49 74.6 18.6 No No
4 empty 2.43 65.8 10.2 No No
5 empty 2.15 71.6 8 No No
6 empty 2.87 52.6 10.1 No No
7 empty 1.89 65.4 7.7 No No
8 empty 2.44 50.4 8.2 No No
9 empty 2.35 57.6 8 No No
10 empty 2.27 58.7 9.2 No No
6FA4_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 71.3 31.9 Yes No
2 empty 2.63 63.4 27.8 No No
3 bound 2.08 75.1 11.9 No No
4 empty 2.32 64.2 15.3 No No
5 empty 2.61 59.1 13.8 No No
6 empty 2.25 58.4 10.5 No No
7 empty 1.86 73.6 7 No No
8 empty 2 65.5 8 No No
9 empty 3.13 73.3 5.5 No No
10 empty 2.75 45.4 6.3 No No
5OCT_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.44 72.7 30.7 Yes No
2 empty 2.31 56.8 26.9 No No
3 bound 2.36 68.3 19.8 No No
4 empty 2.43 61.6 20.8 No No
5 empty 2.46 63.3 9.6 No No
6 empty 1.99 67.9 10.8 No No
7 empty 2.98 63.1 9.8 No No
8 empty 2.13 60.8 8.4 No No
9 empty 2.78 59 7.9 No No
10 empty 2.07 64.6 4.7 No No
5W22_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.41 70.3 38.6 Yes Yes
2 empty 2.53 66.7 17.7 No No
3 empty 2 65.6 11.8 No No
4 empty 2.32 56.9 13.8 No No
5 empty 2.32 58.9 10.5 No No
6 empty 2.24 76.4 9.2 No No
7 empty 1.61 70.1 8.8 No No
8 empty 2.66 60.5 7.4 No No
9 empty 2.78 57.8 9.4 No No
10 empty 2.53 53.8 7.7 No No
6QUW_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.44 78.3 23.8 Yes No
2 empty 2.09 72.7 13.9 No No
3 empty 2.28 66.1 10.2 No No
4 empty 2.03 64.7 9.4 No No
5 empty 2.19 63.8 10.6 No No
6 empty 2.29 63.4 11.2 No No
7 empty 2.31 54.3 13.2 No No
8 empty 2.29 65.2 9.6 No No
9 empty 2.41 60.5 10 No No
10 empty 2.56 59.4 12 No No
6P8Z_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 75.3 17.8 Yes No
2 bound 2.26 75.3 17.2 No No
3 empty 2.21 63.9 19.4 No No
4 empty 2.38 64.9 15.5 No No
5 empty 2.33 62.9 16.3 No No
6 empty 1.83 70.9 9.9 No No
7 empty 1.72 60.9 11.2 No No
8 empty 2.25 55.1 15.3 No No
9 empty 2.28 65.6 7.8 No No
10 empty 2.27 53.4 8.2 No No
6N2K_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 77.6 29.3 Yes No
2 empty 2.56 70.3 21 No No
3 empty 2.14 68.7 18 No No
4 empty 2.39 66.9 12.8 No No
5 empty 2.41 61.8 14.2 No No
6 empty 2.26 64.3 7.2 No No
7 empty 2.63 69.5 7.5 No No
8 empty 1.96 65.6 7.2 No No
9 empty 1.68 60.3 7 No No
10 empty 2.72 61.3 7.6 No No
6EPM_R GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.83 67.8 20.3 No No
2 empty 2.35 62.8 24.2 No No
3 bound 2.48 66.4 20.8 No No
4 empty 2.45 65.7 23.3 No No
5 empty 2.1 61.1 22.2 No No
6 empty 2.2 59.7 15.9 No No
7 empty 1.91 62.8 15.3 No No
8 empty 2.23 71.8 10.8 No No
9 empty 2.21 58.9 10.7 No No
10 empty 1.98 100 0 Yes No
6EPO_R GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 67.1 20.8 No No
2 bound 2.31 72.5 21.9 No No
3 empty 2.35 61.2 24.9 No No
4 empty 2.45 63.1 21.7 No No
5 empty 2.2 62.1 16.1 No No
6 empty 2.17 65.4 12.2 No No
7 empty 2.23 62.2 11.4 No No
8 empty 2.31 64.5 14.5 No No
9 empty 2.29 70 9.5 No No
10 empty 1.75 71.3 10.5 No No
6OB2_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 76.1 23.4 Yes No
2 empty 2.18 74.3 10.8 No No
3 empty 2.07 70.6 12.8 No No
4 empty 2.32 74.9 9.2 No No
5 empty 1.86 49.8 12.2 No No
6 empty 2.49 46.6 11.4 No No
7 empty 2.28 80.8 8.1 No No
8 empty 2.62 58.4 11.8 No No
9 empty 2.69 63.4 10.4 No No
10 empty 2.4 69.9 10.1 No No
4M1T_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.35 70.4 14.8 No No
2 empty 2.63 64.8 25.1 No No
3 empty 2.41 64.4 15.1 No No
4 bound 1.88 71.7 12.3 No No
5 empty 2.25 60.7 17.3 No No
6 empty 2.03 68.6 11.5 No No
7 empty 2.6 59.1 6.9 No No
8 empty 2.19 64.2 8.1 No No
9 empty 2.18 68.5 5.9 No No
10 empty 2.08 57.9 6.7 No No
5UQW_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 71.4 38.4 Yes Yes
2 empty 2.39 72.2 16.9 No No
3 empty 2.23 57.3 13.5 No No
4 empty 2.2 57.5 11.6 No No
5 empty 2.07 70.8 7.3 No No
6 empty 2.37 57 10.6 No No
7 empty 2.18 63.7 7.2 No No
8 empty 2.4 57.6 7.1 No No
9 empty 2.15 55.9 8.6 No No
10 empty 2.26 66.2 7.6 No No
5VQ6_B GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 65.5 23.6 No No
2 empty 2.55 59.8 18.2 No No
3 empty 1.97 67.4 9.7 No No
4 empty 2.52 69.1 16 No No
5 empty 1.9 57.6 9.7 No No
6 empty 2.56 74.8 10 No No
7 empty 2.57 57.3 11 No No
8 empty 2.85 56.6 9.7 No No
9 empty 2.37 62.2 7.7 No No
10 empty 2.51 66.7 6.9 No No
6M9W_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.39 60.5 26.5 Yes No
2 empty 2.38 63.8 24.8 No No
3 empty 2.34 68.3 17.6 No No
4 bound 2.21 66.1 14.4 No No
5 empty 2.46 56.1 10.9 No No
6 empty 2.38 73.5 10.5 No No
7 empty 2.21 69.5 8.7 No No
8 bound 1.66 68.2 8.7 No No
9 empty 2.51 52.1 13.1 No No
10 empty 2.48 51.5 9.3 No No
4PZZ_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 65.9 29.6 Yes No
2 bound 2.14 77.6 16.2 No No
3 empty 2.36 61.1 17.4 No No
4 empty 2.87 57.4 11.4 No No
5 empty 2.16 54.8 9 No No
6 empty 2.29 58.7 8.2 No No
7 empty 2.68 60.5 8.1 No No
8 empty 2.58 46.5 9.8 No No
9 empty 1.86 70.7 6.6 No No
10 empty 2.12 58 7.3 No No
4EPY_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 68.1 27.9 Yes Yes
2 bound 2.06 77 17.7 No No
3 empty 2.49 63.6 24.3 No No
4 empty 2.17 60.3 15.3 No No
5 empty 1.85 68.6 11.7 No No
6 empty 3.01 64.7 11.7 No No
7 empty 2.54 55.1 10.7 No No
8 empty 2.35 70.3 7.6 No No
9 empty 2.18 55.4 6.9 No No
10 empty 2.24 57.9 6.9 No No
4TQ9_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 69.2 28 Yes Yes
2 bound 2.11 79.2 19.4 Yes Yes
3 empty 2.51 62.9 15.8 No No
4 empty 2.4 66.1 17 No No
5 empty 2.79 59.7 17.5 No No
6 empty 2.65 59.2 14.2 No No
7 empty 2.08 72.9 7.9 No No
8 empty 3 62.2 8.7 No No
9 empty 2.41 66.3 7.6 No No
10 empty 2.15 68.9 6.6 No No
6GQY_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.38 73.1 37.2 Yes No
2 empty 2.65 65.7 18.2 No No
3 bound 2.34 64.9 25.9 No No
4 empty 2.47 51.8 19.5 No No
5 empty 2.08 70.6 7.5 No No
6 empty 2.25 58.1 8.6 No No
7 empty 2.78 63.7 7.4 No No
8 empty 2.27 64.4 5.3 No No
9 empty 2.52 57.1 6.8 No No
10 empty 1.52 65.7 6.1 No No
5V9O_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 73.3 34.4 Yes Yes
2 empty 2.38 65 13.2 No No
3 empty 2.44 55.5 19.1 No No
4 empty 2.35 71 11.4 No No
5 empty 2.37 72.7 14.8 No No
6 empty 2.53 59 10.2 No No
7 empty 1.72 64.3 10 No No
8 empty 2.76 60.9 8.7 No No
9 empty 2.51 50.9 12.7 No No
10 empty 2.66 60.6 9.4 No No
6FA2_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 71.4 22.6 Yes Yes
2 empty 2.72 64 25.4 No No
3 empty 2.38 52 18.4 No No
4 bound 2.44 64.7 14.4 No No
5 empty 2.19 65.4 10.1 No No
6 empty 1.95 68.6 10.7 No No
7 empty 2.23 62.7 9.5 No No
8 empty 2.87 65.7 11.3 No No
9 empty 2.12 58 9.7 No No
10 empty 2.48 69.6 6.7 No No
5V71_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 69.2 41.3 Yes No
2 empty 2.71 62.2 29.1 No No
3 empty 2.1 54.3 14.5 No No
4 empty 2.59 59.2 19.1 No No
5 empty 2.13 69.4 8.3 No No
6 empty 2.14 49.4 15.2 No No
7 empty 2.37 65.4 11.7 No No
8 empty 2.98 65.1 10.9 No No
9 empty 2.77 57.9 7.7 No No
10 empty 2.39 67.4 7.6 No No
6FA1_D GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 72.9 24.3 Yes No
2 empty 2.63 62.1 27.9 No No
3 empty 2.47 52.4 18.9 No No
4 empty 2.28 64.3 17.3 No No
5 empty 2.32 66.7 12.2 No No
6 empty 1.9 78.4 9.7 No No
7 empty 1.87 64.9 10 No No
8 empty 2.9 67.9 10.5 No No
9 empty 1.96 65.2 7.2 No No
10 empty 2.53 63.6 5.8 No No
5KYK_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.36 67.7 24.5 Yes Yes
2 empty 2.57 69.5 26.1 No No
3 empty 2.23 61.9 22.3 No No
4 empty 1.92 64.7 11.9 No No
5 empty 2.16 59.8 15.4 No No
6 empty 2.26 75.1 9.9 No No
7 empty 2.56 53.9 11.1 No No
8 empty 2.87 56.6 11.2 No No
9 empty 2.56 67.9 8.4 No No
10 empty 3.07 62.7 11.2 No No
5USJ_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 74.9 22.3 Yes No
2 empty 2.18 67.9 17.2 No No
3 empty 2.53 66.7 19.3 No No
4 empty 2.31 52 13 No No
5 empty 2.28 72.8 10.9 No No
6 empty 2.62 56.7 20.2 No No
7 empty 1.98 64.8 10.9 No No
8 empty 2.25 61.3 7.2 No No
9 empty 2.12 63.9 15.1 No No
10 empty 2.79 62 12.3 No No
5V9L_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 68.4 42 Yes Yes
2 empty 2.66 64.8 23.2 No No
3 empty 2.33 61.1 13.2 No No
4 empty 2.2 67.5 17 No No
5 empty 2.46 65 12.6 No No
6 empty 2.7 58.3 10.3 No No
7 empty 2.1 64.6 6.8 No No
8 empty 2.53 63.2 8.4 No No
9 empty 2.55 64.6 7.6 No No
10 empty 1.2 69.4 6.6 No No
6QUX_B GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 76.8 23.5 Yes Yes
2 empty 2.4 64.2 17.3 No No
3 empty 2.58 73.8 13.4 No No
4 bound 2.11 68 14.6 No No
5 empty 2.2 72.5 9.5 No No
6 empty 2.29 59.3 15.5 No No
7 empty 2.33 71.6 8.5 No No
8 empty 3.14 57.2 11.1 No No
9 empty 3.17 65.4 4.9 No No
10 empty 2.31 99 0 Yes No
5WHE_D GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 73.8 29.1 Yes Yes
2 empty 2.44 63.5 19.4 No No
3 bound 2.09 69 15 No No
4 empty 2.24 63.4 12 No No
5 empty 2.34 67.9 18.4 No No
6 empty 2.55 67.6 14.9 No No
7 empty 2.39 84.4 8.3 Yes No
8 empty 2.45 61.9 8.5 No No
9 empty 2.48 59.1 6.3 No No
10 empty 2.77 58.8 9.2 No No
6GOE_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 72.2 32.2 Yes Yes
2 empty 2.61 67.5 20.4 No No
3 empty 2.35 66.9 13.3 No No
4 empty 2.28 76.4 9 No No
5 empty 2.07 59.9 13.6 No No
6 empty 1.66 65.7 11.3 No No
7 empty 2.62 62.8 10.1 No No
8 empty 2.73 53.4 12.8 No No
9 empty 2.56 68.6 7.2 No No
10 empty 3.06 61.2 8.3 No No
6CU6_C GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.4 64.6 18.7 No No
2 bound 1.67 70.4 16.7 No No
3 empty 1.66 66.8 14.2 No No
4 empty 2.58 72.7 11.1 No No
5 empty 2.3 58.3 13.3 No No
6 empty 2.25 62.1 8.9 No No
7 empty 2.71 67.3 10.6 No No
8 empty 2.94 59.8 10.6 No No
9 empty 1.8 74.8 6.9 No No
10 empty 2.71 57.4 9 No No
6QUU_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.42 78.1 25.5 Yes No
2 empty 2.01 70.9 12.4 No No
3 empty 2.34 65.9 11.3 No No
4 empty 2.69 65.4 18.9 No No
5 empty 2.08 66 7.6 No No
6 empty 2.22 62.7 12 No No
7 empty 2.11 59.3 9.4 No No
8 empty 1.96 62.8 9.4 No No
9 empty 2.63 65.1 8.5 No No
10 empty 2.82 64.2 9.5 No No
6P8X_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 78.2 33.2 Yes Yes
2 empty 2.2 64.9 18.8 No No
3 empty 2.39 68.1 18.3 No No
4 empty 2.19 62.8 12.6 No No
5 empty 1.94 59.7 9 No No
6 empty 2.47 65.5 10.8 No No
7 empty 2.06 73.4 8.7 No No
8 empty 2.87 54.8 8.3 No No
9 empty 2.66 72.7 7.9 No No
10 empty 2.93 65.9 6.3 No No
5US4_B GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 72.4 21.3 Yes No
2 empty 2.63 59.3 15.9 No No
3 empty 2.38 76.5 8.6 No No
4 empty 2.07 65.4 8.4 No No
5 empty 2.43 73.1 9.2 No No
6 empty 1.87 69.3 8.9 No No
7 empty 2.8 61.6 11.1 No No
8 empty 2.23 63.2 7.9 No No
9 empty 2.19 55.5 10.1 No No
10 empty 2.55 63.4 8.4 No No
5V71_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 70.2 39.3 Yes No
2 empty 2.39 67.9 18.2 No No
3 empty 1.9 73 8.6 No No
4 empty 2.3 70.9 12.8 No No
5 empty 2.57 58.7 13.6 No No
6 empty 2.55 60.1 10.6 No No
7 empty 2.16 62.7 8.3 No No
8 empty 2.9 58.2 10.1 No No
9 empty 2.45 54.4 9.2 No No
10 empty 2.23 47.1 8.4 No No
5V71_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 66 30.9 Yes No
2 bound 2.14 77.1 19 No No
3 empty 2.41 67.3 22.9 No No
4 empty 2.25 62 13.9 No No
5 empty 2.07 66.3 11.3 No No
6 empty 2.5 60.5 12.1 No No
7 empty 2.79 60.5 11.1 No No
8 empty 1.88 66.5 9.4 No No
9 empty 2.04 70.5 8.2 No No
10 empty 2.86 62 10 No No
6GJ7_A GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.52 73.9 26.2 Yes Yes
2 empty 2.55 61.3 17.5 No No
3 empty 2.52 69 17.7 No No
4 empty 2.26 67.8 15.8 No No
5 bound 1.9 72.9 9.3 No No
6 empty 2.99 66.8 6.6 No No
7 empty 2.31 68.4 7.5 No No
8 empty 2.31 57.1 12.3 No No
9 empty 2.44 69 7 No No
10 empty 1.9 73.2 5.3 No No
5OCO_D GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.39 72.9 24.5 Yes No
2 empty 2.29 52.8 19.1 No No
3 empty 2.4 66.6 17.3 No No
4 empty 2.19 70.3 14.6 No No
5 empty 2.3 62.4 17.8 No No
6 bound 2.1 71.2 10.6 No No
7 empty 2.31 63.3 14.5 No No
8 empty 1.84 68.5 10.3 No No
9 empty 3 56.9 7.1 No No
10 empty 2.44 51.9 8.2 No No
6ASA_A GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 72.7 23.8 Yes No
2 empty 2.42 64.5 22.5 No No
3 empty 2.59 66.5 21.1 No No
4 empty 2.14 61.6 15.6 No No
5 empty 2.55 62.7 17.1 No No
6 empty 2.24 71.8 13.9 No No
7 empty 1.72 58.9 12.2 No No
8 empty 2.56 63 12.7 No No
9 empty 2.53 81.4 5.6 No No
10 empty 2.87 57.5 9.2 No No
6GQX_D GTPase KRas No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 66.4 19.3 No No
2 empty 2.39 66.6 17.5 No No
3 empty 2.52 50.8 19.9 No No
4 empty 2.53 63.5 19 No No
5 empty 2.39 62.7 12.5 No No
6 empty 2.21 71.8 10.3 No No
7 empty 2.17 62.1 9.4 No No
8 empty 2.14 61.8 6.8 No No
9 empty 2.8 66.7 8.3 No No
10 empty 2.07 57.8 6.9 No No
6FA4_E GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.53 70.6 32.1 Yes Yes
2 empty 2.55 51.4 19.7 No No
3 empty 2.68 64.7 19 No No
4 empty 2.27 61 16.9 No No
5 empty 2.04 70.7 10.8 No No
6 empty 2.09 75.6 6 No No
7 empty 2.38 56.8 12.1 No No
8 empty 2.09 65.2 7.2 No No
9 empty 2.97 66.9 5.7 No No
10 empty 2.43 67.5 5.4 No No
5V9L_C GTPase KRas Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 69 40.7 Yes Yes
2 empty 2.81 64.2 23.9 No No
3 empty 2.17 62.2 14 No No
4 empty 1.78 71.1 9.4 No No
5 empty 2.05 51.8 12.3 No No
6 empty 2.53 61.2 11 No No
7 empty 2.32 58.7 8.3 No No
8 empty 1.72 65 6.3 No No
9 empty 2.21 58.8 8.3 No No
10 empty 2.78 57.8 7.5 No No
6GQW_E GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.32 74.3 23 Yes No
2 empty 2.4 53.5 19.2 No No
3 empty 2.68 66.6 21.7 No No
4 empty 2.4 68 13.7 No No
5 empty 2.58 67.3 16 No No
6 empty 1.97 72.5 7.6 No No
7 empty 2.18 62.8 10.3 No No
8 empty 2.39 52.6 8.7 No No
9 empty 2.09 61.5 7.5 No No
10 empty 2.66 58.9 6 No No
6GOG_C GTPase KRas Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 73.5 33.7 Yes No
2 empty 2.22 67.8 21.7 No No
3 empty 2.33 50.1 18.7 No No
4 empty 2.43 65 16 No No
5 empty 1.89 56.1 13.7 No No
6 empty 1.92 72.1 11 No No
7 empty 2.4 58.3 10.2 No No
8 empty 2.23 55.2 10 No No
9 empty 1.15 74.6 7.6 No No
10 empty 2.59 66.7 6.6 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed1
Domains assessed as druggable using the strict criteria0
Domains assessed as druggable using the relaxed criteria1

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
3GFT_A (3430462) GTPase KRas P-loop containing nucleoside triphosphate hydrolases, P-loop containing nucleoside triphosphate hydrolases, UNMATCHED 2.1Å Yes No
Ligand-based Druggability Score: -3
Ligand-based Druggability Score Percentile: 59%
Ligand-based Druggability Help: Help




		
Number of proteins in the network : 13346


KRAS is involved in 36 interactions in the network.


Druggability
Overall Druggability Percentile: 69.10
Druggability for Cancer Therapeutics: 70.70
Druggability for Other Therapeutics: 68.52
Cancer-Associated
Cancer-associated percentile : 84.24
Network Articulation Point
Is KRAS critical for communication in the network?


Detailed Graph Legend:Help