Molecular Target Synopsis
Overview
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Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Interaction Network
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Gene Copy Number Variation
RNAi
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Germline Genetics

(P00974) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/04/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 23/04/2019)


Chains assessed202
Chains with at least one site assessed as druggable using the strict criteria1
Chains with at least one site assessed as druggable using the relaxed criteria20


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
3GYM_J Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 58.1 12.7 No No
2 empty 2.04 66.9 9.7 No No
3 empty 2.17 59.2 6.5 No No
4 empty 2.91 62.5 6.7 No No
5 empty 1.75 57.1 5.8 No No
6 empty 2.24 66.3 5.3 No No
7 empty 2.82 62.5 4.8 No No
4WXV_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 61.8 13.9 No No
2 bound 1.94 57.4 7.8 No No
3 empty 2.14 57.5 10.5 No No
4 bound 2.87 65.6 7.2 No No
5 empty 2.77 62.5 6.2 No No
6 empty 2.8 72.5 4 No No
7 empty 2.64 62.7 4.8 No No
4Y10_I Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 62.8 11.1 No No
2 bound 2.14 58.3 17.5 No No
3 bound 2.44 64.6 12.4 No No
4 empty 1.83 64.7 9.8 No No
5 empty 1.99 59.3 8.7 No No
6 empty 2.51 62.6 5.4 No No
7 empty 2.82 65.3 5.2 No No
8 empty 2.09 100 0 Yes No
9 empty 3.17 68.6 4.7 No No
10 empty 2.66 55.1 5.6 No No
1BHC_G Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 63.8 10.1 No No
2 empty 1.88 69.7 4.9 No No
3 empty 2.7 57.2 9.6 No No
4 empty 2.61 57.5 10.2 No No
5 empty 2.44 57.4 5.5 No No
6 empty 2.16 48.9 6.3 No No
7 empty 2.36 65 5.2 No No
8 empty 3.12 51.3 5.5 No No
9 empty 2.31 47.5 6.4 No No
2IJO_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.57 60.5 12.1 No No
2 empty 2.49 65.5 8.6 No No
3 empty 2.05 59.2 8.5 No No
4 empty 2.96 58.9 6.3 No No
5 empty 1.48 58.5 6.5 No No
6 empty 1.85 72 5.6 No No
5XX7_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 66.4 10.7 No No
2 bound 2.13 56.7 14.7 No No
3 empty 2.89 62.1 11.4 No No
4 empty 2.72 70.6 6.5 No No
5 empty 2.77 61.5 7.9 No No
6 empty 1.93 63.5 5.8 No No
7 empty 2.61 75.5 0 No No
8 empty 2.99 78.9 0 No No
1TPA_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 62.2 12.5 No No
2 empty 2.13 58.8 11.6 No No
3 empty 2.61 52.8 9.6 No No
4 empty 1.9 61.8 8.5 No No
5 empty 2.24 74.2 6.3 No No
6 empty 3.2 71.1 6.4 No No
7 empty 1.82 61.4 5.1 No No
8 empty 1.9 59.5 5.3 No No
9 empty 2.6 64.7 5.5 No No
10 empty 2.2 53.9 5.5 No No
1BHC_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 60.3 9.2 No No
2 empty 2.59 59.3 7.8 No No
3 empty 2.73 69.1 7.1 No No
4 empty 2.49 60.6 9.1 No No
5 empty 1.06 67.6 6.8 No No
6 empty 2.5 59.8 6.5 No No
7 empty 2.92 58.2 4.8 No No
8 empty 2.29 71.3 0 No No
9 empty 2.24 47.2 5.5 No No
10 empty 3.24 48.7 5.5 No No
1BTH_P Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 60.9 13 No No
2 empty 2.22 54.7 11.3 No No
3 empty 2.79 64.9 7.7 No No
4 empty 2.28 47.7 7.8 No No
5 empty 2.81 67.6 5.6 No No
6 empty 2.98 51.3 7.7 No No
7 empty 2.14 60.3 6.6 No No
8 empty 1.87 63.2 5.4 No No
9 empty 2.52 60.3 0 No No
10 empty 3.28 57.1 6 No No
5YVU_I Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 59.1 12.7 No No
2 empty 2.67 52.1 10.8 No No
3 empty 2.3 62.9 9 No No
4 empty 2.4 75.3 7 No No
5 empty 3.25 75 8.4 No No
6 empty 1.82 63.2 8.5 No No
7 empty 3.15 64.2 6 No No
8 empty 1.69 57.9 5.8 No No
9 empty 1.94 100 0 Yes No
3WNY_G Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.53 67.2 9 No No
2 empty 3.01 60 6.3 No No
3 empty 2.13 67.9 5.4 No No
3BTG_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 57.7 14.6 No No
2 empty 1.61 66.7 8.5 No No
3 bound 2.85 64 7.4 No No
4 empty 1.41 62.6 6.1 No No
5 empty 2.42 73.5 5.3 No No
6 empty 2.63 62.3 4.9 No No
5JB4_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.3 59.6 14.2 No No
2 empty 1.61 68.2 8.6 No No
3 empty 2.75 57.5 7.7 No No
4 empty 2.06 71.6 6 No No
5 empty 2.15 55.9 8.4 No No
6 empty 3.32 64.9 5.8 No No
5XX3_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.72 57.8 13.4 No No
2 bound 2.21 58.3 10.5 No No
3 empty 1.87 64.6 7.9 No No
4 empty 2.43 56.4 8.1 No No
5 empty 2.83 73 0 No No
6 empty 2.48 72.3 0 No No
7 empty 1.86 56.9 6.8 No No
8 empty 2.23 46.6 4.7 No No
2HEX_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.54 61.6 11.9 No No
2 empty 2.4 54.1 11.7 No No
3 empty 2.17 58.9 9.6 No No
4 empty 1.9 66.9 8 No No
5 bound 2.85 63 7 No No
6 empty 2.27 53.7 7.6 No No
7 empty 2.26 69.1 5.7 No No
8 empty 1.68 53.9 4.6 No No
3WNY_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.68 68 7.5 No No
2 empty 2.54 69.2 9.7 No No
3 empty 2.32 64 8.8 No No
4 empty 2.72 74.7 0 No No
5 empty 2.42 70.6 4.7 No No
6 empty 2.94 59.8 6.2 No No
1BHC_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.39 64.1 9.4 No No
2 empty 1.81 71 10.3 No No
3 empty 2.81 66.7 6.9 No No
4 empty 2.55 53.7 10.1 No No
5 empty 2.56 57.1 8.3 No No
6 empty 2.32 62.6 6.2 No No
7 empty 2.13 57.9 7 No No
8 empty 3.26 53.7 5.3 No No
9 empty 2.47 52.1 5.6 No No
10 empty 2.3 73.7 0 No No
1BZ5_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.42 55.5 12.7 No No
2 empty 2.55 65.5 9.4 No No
3 empty 1.67 74.5 6.9 No No
4 empty 2.33 54.3 6.8 No No
5 empty 1.88 58.2 5.3 No No
6 empty 1.82 73.5 5.4 No No
7 empty 3.12 55.1 6.2 No No
8 empty 2.91 58.8 4.5 No No
9 empty 1.73 53.5 5.6 No No
3TGI_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 62.6 11.2 No No
2 empty 2.44 61.7 14.1 No No
3 bound 2.78 63.9 13 No No
4 empty 2.16 61.1 8.5 No No
5 empty 2.4 75.5 0 No No
6 bound 2.59 50.6 5.6 No No
7 empty 1.51 62 5.7 No No
1P2O_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 65 11.4 No No
2 bound 2.68 55.1 12.1 No No
3 bound 2.24 56.1 15.5 No No
4 empty 2.55 62.7 7.7 No No
5 empty 3.3 79.5 0 No No
1P2O_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 63.5 12.3 No No
2 empty 2.59 54.5 11.8 No No
3 bound 2.18 57.9 10.3 No No
4 empty 2.47 64.2 7.6 No No
5 empty 1.77 58.8 5.5 No No
6 empty 1.62 71.1 4.9 No No
7 empty 2.16 58 6.4 No No
7PTI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.8 60.6 11.9 No No
2 bound 2.38 55.7 11.6 No No
3 empty 2.67 67.6 7.2 No No
4 empty 2.81 68.5 7.5 No No
5 empty 3.01 55.8 6.9 No No
6 empty 2.08 71.8 5.1 No No
7 empty 1.47 62.3 5 No No
8 empty 2.57 65.8 0 No No
9 empty 2.08 61.5 5.4 No No
5XX8_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 66.9 9 No No
2 empty 2.82 60.2 11.2 No No
3 bound 2.19 55.6 14.4 No No
4 empty 2.77 70.1 8.2 No No
5 empty 1.84 60.9 7.2 No No
6 empty 2.39 66.7 8.8 No No
7 empty 2.68 58.3 8.8 No No
8 empty 2.69 73.1 5 No No
1YKT_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.97 60.6 12.8 No No
2 bound 2.83 62.5 13.2 No No
3 bound 2.3 62.6 12.4 No No
4 empty 2.32 60.8 8.4 No No
5 empty 2.26 60.8 7.2 No No
6 empty 2.69 67.4 5.5 No No
7 empty 2.65 76.5 0 No No
1P2I_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.21 57.3 17.2 No No
2 bound 2.14 54.7 14.9 No No
3 bound 2.31 61.7 11 No No
4 empty 2.87 69.4 5.5 No No
5 empty 2.43 71.4 6.4 No No
6 empty 1.46 60.5 5.8 No No
7 empty 3.19 75.6 5.5 No No
8 empty 3.45 61.2 5.4 No No
9 empty 3.26 49.3 5.3 No No
1BPI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.63 60.2 11.8 No No
2 bound 2.38 59.1 21 No No
3 empty 2.5 62.9 10.4 No No
4 empty 2.01 73.1 8.8 No No
5 empty 2.6 52.2 11.3 No No
6 empty 2.65 63.8 7 No No
7 empty 2.47 68 6.2 No No
8 empty 2.06 40.6 8 No No
9 empty 2.34 69.2 6.3 No No
10 empty 3.14 56.8 6 No No
1BHC_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.77 63 11.2 No No
2 empty 1.85 72.1 12.7 No No
3 empty 2.72 59.3 10.3 No No
4 empty 2.83 70.2 7.6 No No
5 empty 3.2 58.3 5.6 No No
6 empty 3.1 56.2 6.6 No No
7 empty 2.4 80.5 0 No No
8 empty 3.03 58.7 5.5 No No
9 empty 2.61 40.8 6 No No
10 bound 2.65 48.1 5.7 No No
1FAN_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 68.1 11.1 No No
2 empty 2 65.9 15.2 No No
3 empty 2.63 53 10.6 No No
4 empty 2.84 48.2 9.5 No No
5 empty 2.67 65.1 6.9 No No
6 empty 2.76 59.3 8.5 No No
7 empty 1.95 74.1 5.7 No No
8 empty 3.15 60.6 5.3 No No
9 empty 2.87 57.3 0 No No
10 empty 2.81 70.4 4.3 No No
1B0C_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.63 66.1 7.9 No No
2 empty 2.63 57 9 No No
3 empty 2.4 56.8 9 No No
4 empty 1.4 66 7.8 No No
5 empty 1.15 67.6 4.8 No No
6 empty 2.18 52.3 6.3 No No
1FAK_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 58.8 18.5 No No
2 empty 1.64 61.5 12.6 No No
3 empty 2.41 56.7 11.2 No No
4 empty 2.13 62.4 7.2 No No
5 empty 2.3 65.9 4.6 No No
3LDM_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.56 57.2 12.2 No No
2 empty 2.71 60.4 11.3 No No
3 empty 2.48 61.7 9.4 No No
4 empty 1.98 69.9 10.2 No No
5 empty 2.45 54.9 9.5 No No
6 empty 2.53 54.3 6.5 No No
7 empty 1.81 63.6 5.6 No No
8 empty 2.19 61.2 6.6 No No
9 empty 2.14 57.6 7.1 No No
10 empty 2.57 82.3 0 No No
1BHC_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.74 63 12.1 No No
2 empty 2.44 60.7 8.6 No No
3 empty 2.71 63.2 7.8 No No
4 empty 2.23 52.7 7.6 No No
5 empty 2.44 56.6 6.8 No No
6 empty 1.04 65.7 6.8 No No
7 empty 2.26 70.8 4.8 No No
8 empty 3.21 46.6 5.5 No No
9 empty 2.32 43.9 5.3 No No
10 empty 2.85 60.9 5.2 No No
1T8O_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 63.9 12.2 No No
2 empty 2.75 60.1 10.7 No No
3 empty 2.42 63.4 8 No No
4 empty 2.39 64.2 8.4 No No
5 empty 2.15 55.3 10.2 No No
6 empty 2.18 68.6 5.7 No No
7 bound 2.52 54 7.6 No No
8 empty 3.32 71 5.2 No No
9 empty 1.16 71.2 0 No No
5JB7_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.75 64.4 8.1 No No
2 empty 2.73 54.3 8.2 No No
3 empty 2.79 57.3 7.2 No No
6F1F_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.75 58.6 13 No No
2 empty 2.49 63 10.9 No No
3 bound 2.98 71 7.9 No No
4 empty 3 56.7 8.5 No No
5 empty 2.1 64 5.3 No No
6 empty 2.62 71.3 5.7 No No
7 empty 1.49 63.7 7.7 No No
8 empty 2.37 62.2 6.3 No No
9 empty 2.42 61.3 6.1 No No
1K6U_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 58.9 13.9 No No
2 empty 1.54 62 9.6 No No
3 empty 2.27 62.8 9.6 No No
4 empty 2.89 58.7 9.3 No No
5 bound 2.63 63.2 10.4 No No
6 empty 2.6 74 5.5 No No
7 empty 2.39 51.5 6.3 No No
8 bound 3.89 74.6 0 No No
9 empty 3.17 64.7 5.3 No No
3BTF_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 60.1 11.7 No No
2 empty 1.65 63.3 8.2 No No
3 empty 1.83 66.2 8.1 No No
4 bound 2.67 64.2 9.6 No No
5 empty 1.43 65.1 6.5 No No
6 empty 2.17 67.8 6.4 No No
7 empty 2.5 62.2 5.8 No No
3WNY_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.44 65 13.7 No No
2 empty 1.66 68.4 7.3 No No
3 empty 2.18 72.4 4.2 No No
1AAL_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 59.3 11.6 No No
2 empty 2.7 65.9 10.4 No No
3 empty 1.91 75.4 10.2 No No
4 empty 1.81 61.1 9.6 No No
5 empty 2.9 60.8 8.2 No No
6 empty 2.18 57.8 5.9 No No
7 empty 2.27 72.2 5 No No
8 empty 2.35 53.9 6.1 No No
9 empty 3.38 65.7 5.2 No No
3WNY_A Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.69 71.7 7.7 Yes No
2 empty 2.67 57.2 7.7 No No
3 empty 2.14 76.5 0 No No
4 empty 2.48 68.5 4.5 No No
5 empty 3.02 54.8 5.7 No No
5JB5_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 70.8 8.2 No No
2 bound 2.91 68.1 8.8 No No
3 empty 2.43 65.7 6.2 No No
3TPI_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.77 56 12.4 No No
2 empty 2.13 57.3 9.9 No No
3 empty 2.57 53.7 9.9 No No
4 empty 2.18 59.9 9.1 No No
5 empty 2.19 74.5 8.3 No No
6 bound 3.06 63.3 7.3 No No
7 empty .97 59.2 5.1 No No
1T8M_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.65 65.4 12 No No
2 bound 2.67 59.9 13.1 No No
3 bound 2.26 57.1 11.2 No No
4 empty 2.44 59.3 8.6 No No
5 empty 2.58 60.6 8.4 No No
6 empty 2.59 43.1 6.7 No No
7 empty 1.45 70.7 0 No No
1B0C_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 65.3 6.9 No No
2 empty 1.94 71.3 6.7 No No
3 empty 1.65 65.6 5.7 No No
4 empty 2.09 54.6 5.8 No No
5 empty 3.07 63.2 5.2 No No
6 empty 2.79 47.1 5.8 No No
2HEX_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.52 62 11.8 No No
2 bound 2.6 65.2 11.1 No No
3 empty 2.55 52.8 8.4 No No
4 empty 2.85 58.1 7.6 No No
5 empty 1.99 58.5 7.6 No No
6 empty 1.11 62.8 7.6 No No
7 empty 2.15 58 6.3 No No
8 empty 2.2 62.5 5 No No
9 empty 2.51 49.5 6.4 No No
10 empty 3.4 60.7 0 No No
5XX2_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 57.5 16.5 No No
2 empty 1.63 68.1 12 No No
3 empty 2.68 56.3 10.5 No No
4 bound 2.74 62.2 10.8 No No
5 empty 2.73 65.7 7.2 No No
6 empty 2.15 53.4 7.4 No No
7 empty 2.78 76.8 0 No No
8 empty 2.22 60.5 5.6 No No
1T7C_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 64.7 11.5 No No
2 bound 2.68 60 12.7 No No
3 bound 2.28 60.7 9.1 No No
4 empty 2.44 59.5 9.2 No No
5 empty 1.5 72.4 0 No No
6F1F_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.6 54.7 12.7 No No
2 empty 2.54 67.8 7.6 No No
3 bound 2.81 57.3 11.3 No No
4 empty 1.57 62.9 6.7 No No
5 empty 2.2 61.2 6.3 No No
6 empty 2.58 70.1 5.9 No No
7 empty 1.86 50 6.5 No No
8 empty 2.14 50.6 6.7 No No
9 empty 1.64 98.8 0 Yes No
10 empty 2.4 44.6 7.1 No No
6F1F_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 67.1 11.8 No No
2 empty 2.44 63 9.1 No No
3 bound 2.61 65.8 7.1 No No
4 empty 1.62 58.9 6.7 No No
5 empty 2.21 52.2 5.3 No No
6 empty 1.66 63.9 7.4 No No
7 empty 2.11 50 6.5 No No
4Y0Y_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 61.1 21.2 No No
2 empty 1.77 60.5 12.3 No No
3 bound 2.08 55.8 16.3 No No
4 empty 1.57 63.6 9.2 No No
5 empty 1.88 64.6 6.3 No No
6 empty 2.71 66.1 4.4 No No
1T7C_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 65.2 11.5 No No
2 empty 2.65 58.8 11.7 No No
3 bound 2.26 62.1 11.3 No No
4 empty 2.35 61.5 9.8 No No
5 empty 2.59 60.3 5.7 No No
6 empty 3.33 75.7 5 No No
4WWY_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 58.8 12.6 No No
2 bound 2.29 62.3 12 No No
3 bound 2.79 63.9 10.2 No No
4 empty 2.3 62.5 13.9 No No
5 empty 2.51 60.5 8.5 No No
6 empty 1.92 59.2 9.3 No No
7 empty 2.52 68.1 7.2 No No
8 empty 2.75 66.3 5.9 No No
3LDM_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.59 70 12.3 No No
2 empty 2.57 62.7 7.9 No No
3 empty 2.33 55 7 No No
4 empty 2.46 59.7 10.3 No No
5 empty 3.16 60.9 5.7 No No
6 empty 2.7 47.7 7.1 No No
7 empty 3.01 65 7 No No
8 empty 1.6 57.1 7.8 No No
9 empty 2.62 76.1 5 No No
10 empty 3.38 61.2 0 No No
2KAI_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 64.6 11.7 No No
2 empty 2.36 66 9.9 No No
3 empty 2.41 57.5 8.9 No No
4 empty 2.26 58.3 8.5 No No
5 empty 2.78 55.4 8 No No
6 empty 2.07 57.7 7.6 No No
7 empty 2.02 71.1 8.4 No No
8 empty 2.45 66.3 7.3 No No
9 empty 2.94 65.1 7.3 No No
10 empty 2.49 54.5 6.2 No No
1CO7_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.27 62.7 6.4 No No
2 empty 2.57 63.9 7.8 No No
3 empty 2.65 60 8.8 No No
4 empty 2.5 61.2 7 No No
5 empty 2.18 67.4 5.3 No No
6 empty 2.98 61.2 5.1 No No
5JB7_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 65.7 7.6 No No
2 bound 3.08 64.9 9.2 No No
3 empty 2.96 68.4 4.6 No No
1BTI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 61.9 17.9 No No
2 empty 2.26 51.5 15 No No
3 empty 2.47 67.6 13.1 No No
4 empty 2.49 58.1 15.4 No No
5 empty 2.62 57.7 11.3 No No
6 empty 2.38 70.9 5.5 No No
7 empty 3.55 64.6 5.9 No No
8 empty 3.48 58.8 6.1 No No
9 empty 1.68 69.5 5.4 No No
10 empty 2.15 61.8 5.3 No No
1BZ5_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.57 65.4 9.7 No No
2 empty 2.56 57.8 10.2 No No
3 empty 1.75 66.3 8 No No
4 empty 2.41 55.4 7.2 No No
5 empty 1.91 78 0 No No
6 empty 2.26 60.3 7.6 No No
7 empty 2 55.3 6.5 No No
8 empty 3.19 65.8 5 No No
9 empty 3.08 54 6.4 No No
10 empty 1.42 57.7 4.9 No No
3LDM_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.53 64.8 9.1 No No
2 empty 2.5 64.2 6.9 No No
3 empty 2.52 53.7 12.3 No No
4 empty 2.63 56.6 7.7 No No
5 empty 2.11 68 4.1 No No
6 empty 1.74 68.2 4.6 No No
7 empty 2.81 64.5 4.8 No No
8 empty 2.24 71.8 5.8 No No
2ZVX_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 61.4 13.5 No No
2 bound 2.37 57.5 19.9 No No
3 empty 2.01 62.4 9.7 No No
4 empty 2.43 58.2 8 No No
5 empty 2.63 47.1 11 No No
6 empty 2.83 66.3 5.3 No No
7 empty 3.6 57 5.6 No No
3BTK_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 56.8 14.2 No No
2 empty 1.63 65.2 8 No No
3 empty 2.26 63.5 8.4 No No
4 bound 2.86 66.7 8.3 No No
5 empty 1.56 60 5.7 No No
6 empty 2.02 64.8 6.5 No No
7 empty 2.97 63.2 5.6 No No
3LDJ_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 69.6 11.6 No No
2 bound 2.31 54.6 11.7 No No
3 empty 2.04 71.7 6.8 No No
4 empty 3.01 62.9 5.6 No No
5 empty 2.7 41 6.4 No No
6 empty 2.81 46.7 6 No No
7 empty 2.54 64.8 5.1 No No
8 empty 1.98 58.2 5.3 No No
9 empty 1.67 98.8 0 Yes No
5YW1_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.24 57.6 12.2 No No
2 empty 2.92 50.2 11.5 No No
3 empty 2.44 63.2 8.3 No No
4 empty 1.42 66.2 6.9 No No
5 empty 3.23 70.7 6.5 No No
6 empty 1.96 80.6 0 No No
7 empty 3.2 64.6 5.4 No No
8 empty 2.85 56.3 5.5 No No
9 empty 2.38 75 5.8 No No
10 empty 2.82 63.3 5.3 No No
4Y0Z_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.69 60.4 11.4 No No
2 bound 2.48 62.8 10.4 No No
3 bound 2.18 54.4 13.1 No No
4 empty .93 62.5 6.4 No No
5 empty 2.38 69.4 0 No No
6 empty 1.69 68.5 4.9 No No
7 empty 2.43 62.3 5.7 No No
8 empty 2.59 60.8 4.3 No No
5XX5_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 67 8.7 No No
2 bound 2.24 54.3 14.9 No No
3 empty 1.73 60.7 7.8 No No
4 empty 2.73 67.4 10.1 No No
5 empty 2.9 71.7 0 No No
6 empty 2.8 56.9 7.3 No No
7 empty 2.73 71.2 5.2 No No
1T8O_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.9 68.3 10.9 No No
2 bound 2.64 59.1 12.2 No No
3 bound 2.29 58.4 10 No No
4 empty 2.44 64.5 9.4 No No
5 empty 2.08 57.2 11.2 No No
6 empty 1.52 68.4 4.2 No No
1CBW_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 65.7 11.6 No No
2 empty 2.59 54.5 11.8 No No
3 empty 2.67 50.6 8.8 No No
4 empty 2.13 62.4 7.4 No No
5 bound 2.8 77.3 7.5 No No
6 empty 2.05 63 10.2 No No
7 empty 2.64 59.8 8 No No
8 empty 1.66 63.3 7.1 No No
9 empty 3.27 58.2 5 No No
1MTN_D Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 66 11.5 No No
2 empty 2.83 60.4 10.8 No No
3 bound 2.33 59.3 12.4 No No
4 empty 2.1 64.4 7.7 No No
5 empty 2.69 65.3 8.9 No No
6 empty 3.14 65.7 6.8 No No
7 empty 2.96 50.8 7.7 No No
8 empty 2.55 60.3 5.3 No No
9 empty 2.72 73.2 6.3 No No
10 empty 2.39 98.6 0 Yes No
5JB4_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 68.2 7.4 No No
2 empty 2.34 58.8 9.5 No No
3 empty 1.93 72.5 4.9 No No
1JV9_A Pancreatic trypsin inhibitor Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 60.6 9.7 No No
2 empty 2.48 80 9.6 Yes Yes
3 empty 2.86 49.3 9.7 No No
4 empty 2.58 60.8 6.8 No No
5 empty 3.32 56 8.4 No No
6 empty 2.48 70.3 6.7 No No
7 empty 2.63 64.9 8 No No
8 empty 2.61 59.4 6.4 No No
9 empty 1.92 57.8 5.3 No No
10 empty 3.17 41.6 6 No No
1EJM_F Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 66.4 11 No No
2 empty 2.49 51.2 16.3 No No
3 bound 2.3 59.6 9.5 No No
4 empty 2.36 56.3 11.2 No No
5 empty 2.73 52.8 6.9 No No
6 empty 3.08 60.7 5.1 No No
7 empty 2.78 63.3 5.6 No No
8 empty 3.48 66.7 5.6 No No
9 empty 1.5 67.8 6.1 No No
10 empty 2.11 59 5.4 No No
1PIT_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 62.6 12.4 No No
2 empty 2.26 63.6 12.2 No No
3 empty 2.32 58.5 11.7 No No
4 empty 2.43 60.7 8.1 No No
5 empty 2.67 65.7 9 No No
6 empty 1.86 66 5.3 No No
7 empty 1.82 65.5 6.7 No No
8 empty 2.58 64.8 7.1 No No
9 empty 3.14 57.1 6.5 No No
1T8L_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 63.1 11.8 No No
2 bound 2.64 58.1 12.8 No No
3 bound 2.32 58.2 9.7 No No
4 empty 2.48 63.7 8.3 No No
5 empty 1.94 48.7 8.7 No No
6 empty 2.01 54.8 9.3 No No
7 empty 3.07 64.2 7.4 No No
8 empty 1.37 64.4 4.9 No No
9 bound 3.34 64 5.9 No No
2PTC_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 67.8 12.9 No No
2 empty 2.21 59.6 12.2 No No
3 empty 2.49 50.5 9.8 No No
4 empty 1.9 59.3 8.5 No No
5 empty 1.56 58 5.7 No No
6 empty 2.92 66.1 6.7 No No
7 empty 2.26 73.7 6.3 No No
8 empty 2.26 56.1 5.6 No No
1G6X_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.52 58.1 9.8 No No
2 bound 2.22 62.9 7 No No
3 empty 2.85 55.2 9.4 No No
4 bound 2.58 64.9 10.8 No No
5 empty 2.62 52.5 6.6 No No
6 bound 2.86 52.3 6.6 No No
7 empty 2.69 65 5.1 No No
8 empty 2.82 73 0 No No
9 empty 2.37 63 6.1 No No
10 empty 2.57 32.4 5.7 No No
5JB7_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 68.9 7.8 No No
2 bound 2.63 63 8.9 No No
3 empty 2.57 73.1 5.1 No No
2RA3_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 58.1 13.3 No No
2 empty 2.75 67.8 12.8 No No
3 bound 2.88 61.1 13 No No
4 empty 1.74 67.5 13.7 No No
5 empty 2.17 64 6.7 No No
6 empty 1.89 58.6 6.6 No No
7 empty 2.56 74 5.3 No No
8 empty 2.81 71.6 0 No No
9 empty 2.25 42.6 8.3 No No
10 empty 2.95 57.1 6.5 No No
1B0C_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 66.2 7.8 No No
2 empty 2.72 57.8 8.6 No No
3 empty 2.76 63.5 8 No No
4 empty 1.74 72 6.9 No No
5 empty 1.66 67.7 5.6 No No
6 empty 2.72 57.4 7.8 No No
7 empty 2.4 63.4 8 No No
8 empty 2.19 53.9 5.9 No No
9 empty 2.65 58.1 4.7 No No
10 empty 3.23 55.7 5.8 No No
1MTN_H Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 63.8 10.1 No No
2 empty 2.88 58.4 12.1 No No
3 empty 2.1 68.4 10.3 No No
4 empty 2.09 66.4 9.1 No No
5 empty 2.5 64.4 9.4 No No
6 empty 2.91 70.9 6.2 No No
7 empty 2.64 72.7 6.3 No No
8 empty 3.09 47.4 5.6 No No
9 empty 2.48 55.7 5.2 No No
10 empty 2.22 64.9 4.4 No No
5JB6_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.57 60.6 10.7 No No
2 empty 1.91 65.6 8.4 No No
3 empty 2.68 54.5 8.8 No No
4 empty 3.05 67.9 0 No No
5 empty 2.73 54.1 5.8 No No
6F1F_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.61 57 11.8 No No
2 empty 2.58 62.9 8.3 No No
3 bound 2.91 66.8 10 No No
4 empty 1.86 59.7 9 No No
5 empty 2.07 64.8 4.9 No No
6 empty 2.13 52.2 5.3 No No
7 empty 2.22 56.6 5.5 No No
8 empty 2.69 76 0 No No
9 empty 2.32 73.1 5.8 No No
10 empty 2.87 38.5 6.2 No No
4BNR_J Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.77 68.5 9 No No
2 empty 2.22 60.1 13.6 No No
3 empty 2.18 57.7 8.8 No No
4 bound 3.01 70.7 7.6 No No
5 empty 2.6 58.9 7.2 No No
6 empty 2.73 61 5.5 No No
7 empty 2.52 73.1 0 No No
8 empty 3.26 67.6 6.7 No No
2ZJX_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 60.6 11.2 No No
2 empty 2.72 57.8 12.7 No No
3 bound 2.33 58.5 16.7 No No
4 empty 2.96 71 0 No No
5 empty 2.47 70.8 0 No No
6 empty 2.32 50.5 5.6 No No
1YLC_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 60.3 13.1 No No
2 empty 2.25 64.2 11 No No
3 bound 2.75 70.6 9.2 No No
4 empty 2.18 58.6 7.8 No No
5 empty 2.78 58 6.7 No No
6 empty 2.12 58.2 6.8 No No
7 empty 2.61 75.3 0 No No
8 empty 1.56 60 5.6 No No
9 bound 2.57 48.6 5.6 No No
10 empty 3.24 74 0 No No
3LDI_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 56.3 12 No No
2 empty 2.5 65.3 8.5 No No
3 bound 2.76 64.1 9.3 No No
4 bound 2.44 58.5 11.2 No No
5 empty 2.39 66.4 6.4 No No
6 empty 1.95 65.1 4.6 No No
7 empty 2.3 56.5 5.4 No No
8 empty 2.58 46.9 7.5 No No
9 empty 2.24 61.3 6.6 No No
10 empty 3.12 57.9 6.1 No No
5XX3_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 57 19.2 No No
2 bound 2.45 61.3 13.7 No No
3 empty 2 61.5 10.3 No No
4 empty 2.72 54.7 8.5 No No
5 empty 2.47 61.6 8.7 No No
6 empty 2.62 56.1 7.6 No No
7 empty 2.82 41.3 9 No No
8 empty 2.65 52.3 6.9 No No
1EAW_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 63.3 10.6 No No
2 empty 2.88 62.5 10.5 No No
3 empty 1.98 54.1 10.2 No No
4 empty 2.32 61.1 7.4 No No
5 empty 2.9 51.7 8 No No
6 empty 1.91 63.1 10 No No
7 empty 2.58 72.2 0 No No
8 empty 2.56 70.7 5.6 No No
9 empty 3.46 58.7 0 No No
10 empty 3.49 63 5.5 No No
4DG4_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.8 65.1 11.2 No No
2 bound 2.75 56.1 12.8 No No
3 bound 2.17 55.1 14.3 No No
4 empty 2.52 57.6 10.6 No No
5 empty 2.34 67.3 10.1 No No
6 empty 1.19 66.4 5.6 No No
7 empty 2.06 58.3 7.3 No No
8 empty 2.4 65.8 6.2 No No
4Y11_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.54 61.9 15.4 No No
2 empty 1.73 55.9 13.2 No No
3 bound 2.12 56.3 16.7 No No
4 empty 1.58 71.9 8.2 No No
5 empty 1.96 61.7 8.1 No No
6 empty 2.31 62.9 4.3 No No
1EJM_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 64.5 11.6 No No
2 empty 2.67 50.3 17.6 No No
3 bound 2.17 59.8 11.8 No No
4 empty 1.92 69 7.5 No No
5 empty 2.66 48.6 7.2 No No
6 empty 2.38 67.4 6.7 No No
7 empty 2.84 63.9 4.3 No No
8 empty 2.86 63.3 5.1 No No
9 empty 3.4 63.9 5.1 No No
2R9P_F Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.69 59.3 12 No No
2 empty 2.42 49.5 14.7 No No
3 bound 2.67 67.9 10.6 No No
4 empty 2.26 61.1 7.6 No No
5 empty 2.55 60.7 7 No No
6 empty 1.53 58.9 6.9 No No
7 empty 2.45 66.7 5.7 No No
8 empty 2.52 62.6 4.8 No No
9 empty 2.08 54.4 7.6 No No
10 empty 3.45 62.5 6 No No
4DG4_F Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 60.7 12.5 No No
2 bound 2.79 59.9 11.1 No No
3 bound 2.23 58.6 9.3 No No
4 empty 2.33 65.7 10.3 No No
5 empty 2.71 59.5 7.4 No No
6 empty 2.27 57.5 9.3 No No
7 empty 1.15 57.4 7.6 No No
8 empty 2.35 70.7 8 No No
9 empty 3.55 60.6 5 No No
4DG4_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.42 60.6 11.9 No No
2 bound 2.73 62.3 10.9 No No
3 bound 2.39 60.9 11.3 No No
4 empty 2.35 67.5 10.3 No No
5 empty 2.56 57.2 8.3 No No
6 empty 2.33 58.5 8.8 No No
7 empty 1.41 57.4 5.5 No No
8 empty 2.65 75 5.9 No No
1F7Z_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.62 61.3 12.3 No No
2 bound 2.39 57.9 14.4 No No
3 bound 2.66 68.2 10.3 No No
4 empty 2.32 63.5 9.2 No No
5 empty 2.36 64.4 8.7 No No
6 empty 2.95 61 4.9 No No
7 empty .83 59.2 6.1 No No
8 empty 3.13 57.9 6 No No
1T8M_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.58 64.8 11.8 No No
2 empty 2.74 58.1 11.7 No No
3 bound 2.29 62.8 10.2 No No
4 empty 2.33 63.1 8.8 No No
5 empty 2.31 58.5 9.8 No No
6 empty 2.62 77.2 0 No No
1P2N_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.62 63.2 12.1 No No
2 empty 2.68 52.9 12.2 No No
3 bound 2.44 60.9 10.9 No No
4 empty 2.44 64.9 9.8 No No
5 empty 2.07 57.9 8 No No
6 empty 1.01 67.1 4.2 No No
3TGJ_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 59.2 11.2 No No
2 bound 2.85 62.3 14 No No
3 empty 2.27 63.8 11.9 No No
4 empty 2.61 59.5 8.7 No No
5 empty 2.33 62.6 7.7 No No
6 bound 2.58 54.4 6.6 No No
8PTI_A Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 71.7 10 Yes No
2 empty 2.08 63.4 8.2 No No
3 empty 1.9 55.3 12.3 No No
4 empty 1.28 65.2 5.6 No No
5 empty 2.5 67.9 5 No No
6 empty 3.11 72.4 5.2 No No
1T8L_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.71 63.9 12.2 No No
2 empty 2.63 58.2 12 No No
3 bound 2.23 59.3 10.1 No No
4 empty 2.3 58.9 12.3 No No
5 empty 2.35 62 9.6 No No
6 empty 1.93 63.1 9.6 No No
3U1J_E Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 55.9 19.3 No No
2 empty 1.64 72.3 8.5 Yes No
3 empty 2.13 57.1 10.5 No No
4 empty 2.63 70.9 5.5 No No
5 empty 3.1 58.2 6.1 No No
6 empty 2.24 66.7 6.4 No No
7 empty 2.99 64.4 5.3 No No
3BTW_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 57.3 12.2 No No
2 empty 1.69 63.3 8.1 No No
3 empty 2 62.3 9.3 No No
4 empty 2.32 47.9 8.3 No No
5 bound 3.05 62.8 8.1 No No
6 empty 1.44 60.8 5.6 No No
7 empty 2 66.7 5 No No
5XX4_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.6 61.6 16.5 No No
2 bound 2.13 59.6 14 No No
3 empty 1.74 70.1 7.8 No No
4 empty 2.87 67.6 5.1 No No
5 empty 2.5 62 7.4 No No
6 empty 1.59 62.3 5 No No
7 empty 3.12 64.9 5.9 No No
2FTM_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.21 63.4 12.8 No No
2 bound 2.35 60.1 11.2 No No
3 bound 2.66 58.4 10 No No
4 empty 1.63 67.3 7.9 No No
5 empty 1.84 58.3 8.8 No No
6 empty 1.57 62.6 6.7 No No
7 empty 2.74 68.6 5.7 No No
8 empty 1.79 75.9 5.9 No No
9 empty 2.75 100 0 Yes No
10 empty 2.41 56.5 5.4 No No
3FP8_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.74 62.2 12.6 No No
2 empty 1.61 70.3 7.8 No No
3 empty 2.32 57.5 11.4 No No
4 empty 2.28 50 8.6 No No
5 empty 2.33 62.1 8 No No
6 empty 2.22 53.3 7.3 No No
7 bound 2.64 54.7 6.9 No No
8 empty 1.15 67.1 5.5 No No
5JB6_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 70.9 8.2 No No
2 bound 2.54 68.9 9.2 No No
3 empty 2.64 64.9 0 No No
1P2K_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.62 59.5 12.4 No No
2 empty 1.81 59.3 12.3 No No
3 bound 2.13 57.8 13.8 No No
4 empty 2.85 68 5.7 No No
5 empty 2.48 70.9 5.4 No No
6 empty 3.25 50.7 5.4 No No
7 empty 1.03 63.8 4.9 No No
1LD6_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 66.1 12.4 No No
2 empty 2.49 60.4 14.5 No No
3 empty 2.48 62.2 12.7 No No
4 empty 2.51 57.3 11.2 No No
5 empty 2.11 60.9 12.4 No No
6 empty 2.57 78.8 8.8 No No
7 empty 2.7 61 8.7 No No
8 empty 2.05 63.2 6.6 No No
9 empty 2.98 53.1 7.7 No No
10 empty 2.7 65 6.9 No No
1NAG_A Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.74 59.6 11 No No
2 empty 2.77 57.9 10.4 No No
3 bound 2.47 59.4 12.6 No No
4 empty 2.61 62.3 7.7 No No
5 empty 1.88 56.3 9.4 No No
6 empty 2.4 71.5 0 No No
7 empty 3.15 46.6 6.1 No No
8 empty 2.67 91.2 3.5 Yes No
9 empty 3.35 58.6 6.1 No No
1YLD_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 60 11.1 No No
2 bound 2.7 74.4 8.2 No No
3 empty 1.5 69.8 8.2 No No
4 empty 2.25 63.8 7.1 No No
5 empty 2.54 57.1 9.5 No No
6 empty 2.7 53.1 7.2 No No
7 empty 2.66 70.7 5.6 No No
8 empty 1 68.2 5.8 No No
9 bound 2.48 56.2 7.2 No No
10 No No
3LDM_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 58.8 11.9 No No
2 empty 2.54 66.7 8.6 No No
3 empty 1.5 66.5 9.7 No No
4 empty 2.3 49.6 6.7 No No
5 empty 2.12 72.9 0 No No
6 empty 2.69 62 6 No No
7 empty 2.93 56.5 6.2 No No
8 empty 2.49 49.1 7.3 No No
9 empty 2.73 59.7 6.2 No No
10 empty 3.35 54.2 5.1 No No
5JB5_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 66.9 8.5 No No
2 bound 2.62 66.2 9.7 No No
3 empty 2.66 73.7 6.6 No No
5XX7_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 57.5 17 No No
2 empty 1.94 70.2 9.3 No No
3 bound 2.3 60.3 13 No No
4 empty 2.54 52.2 12.1 No No
5 empty 2.77 59 9.1 No No
6 empty 2.53 47.8 8.5 No No
7 empty 3.77 53.8 6.2 No No
8 empty 2.91 68.9 5.3 No No
1T8N_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.65 63.6 11.9 No No
2 bound 2.2 57.8 16.1 No No
3 bound 2.74 48.1 11.2 No No
4 empty 2.45 61.2 8.2 No No
5 bound 3.11 76.3 7.6 No No
6 empty 1.53 72.4 0 No No
7 empty 2.29 51.8 6.3 No No
1BHC_J Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.68 61.5 12.3 No No
2 empty 2.66 68.6 8 No No
3 empty 2.65 58 9.1 No No
4 empty .98 66 6.3 No No
5 empty 2.3 60.2 6.2 No No
6 empty 2.39 57.1 4.5 No No
7 empty 2.63 53.4 7 No No
8 empty 2.86 58.5 5.3 No No
9 empty 2.46 73 0 No No
10 empty 3.45 51.3 5.6 No No
1UUA_A Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 70.7 11.3 No No
2 empty 1.94 54.6 15.4 No No
3 empty 1.78 61.6 12.1 No No
4 empty 2.37 59.9 11.2 No No
5 empty 2.63 61.6 8.3 No No
6 empty 3.71 50 6.1 No No
7 empty 2.62 98.9 0 Yes No
8 empty 2.21 63.1 5.6 No No
9 empty .77 63.2 0 No No
3BTD_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 56.6 12.7 No No
2 empty 1.55 68.2 8.5 No No
3 bound 3.2 65.8 7.5 No No
4 empty 2.43 70.5 6.7 No No
5 empty .92 58.8 6 No No
6 empty 3.03 67.1 5.6 No No
7 empty 2.62 58.9 5.8 No No
8 empty 1.94 66.1 5.3 No No
9 empty 3.01 60 5.3 No No
6F1F_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 60.6 12.6 No No
2 bound 2.82 61.7 12.2 No No
3 empty 2.43 60.2 7.7 No No
4 empty 1.77 68 11.2 No No
5 bound 2.59 56.9 9.3 No No
6 empty 2.54 70.5 0 No No
7 empty 1.74 53.7 6.8 No No
8 empty 2.56 48.9 6.9 No No
1T8N_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 66.5 12.8 No No
2 bound 2.21 62.2 11 No No
3 empty 2.63 58 13.6 No No
4 empty 2.43 61.1 8.3 No No
5 empty 2.82 66.7 6.2 No No
4WXV_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.66 57.7 11 No No
2 bound 2.18 56 15 No No
3 empty 2.34 63.7 6.4 No No
4 empty 2.57 69.5 5.3 No No
5 empty 1.53 64.2 5.7 No No
6 empty 2.28 68.1 5.4 No No
7 empty 2.95 55 7.8 No No
8 empty 2.03 68.9 6.6 No No
1BRB_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 66.8 9.7 No No
2 empty 2.41 60.6 10.9 No No
3 empty 2.02 60.7 11.8 No No
4 empty 2.8 68.4 10.2 No No
5 empty 2.89 60 8 No No
6 empty 2.04 71.3 0 No No
7 empty 2.51 57.1 6.8 No No
8 empty 3.1 63.6 5.3 No No
3LDI_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.42 63.2 9.9 No No
2 empty 1.62 62.4 9.6 No No
3 empty 2.45 49.4 9.5 No No
4 bound 2.83 60.9 8.6 No No
5 empty 2.64 63.5 6.8 No No
6 empty 2.23 67 6.5 No No
7 empty 2.17 57 6.1 No No
8 empty 3.16 63.1 5.5 No No
9 bound 2.59 53 5.5 No No
10 empty 1.22 68.8 4.7 No No
2FTL_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 58.1 13.1 No No
2 bound 2.12 58.9 13.1 No No
3 bound 2.37 62.4 10.3 No No
4 empty 2.19 55.8 9.5 No No
5 empty 2.74 60.8 8.6 No No
6 empty .95 59.2 5.8 No No
7 empty 2.71 69.8 5.9 No No
8 empty 1.94 75 4.6 No No
9 empty 2.82 68.2 4.6 No No
1BHC_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 63.9 11.5 No No
2 empty 1.66 72.6 10.3 Yes No
3 empty 2.76 67.1 9.1 No No
4 empty 2.39 52.2 8.4 No No
5 empty 2.38 46.3 7 No No
6 empty 2.94 53.1 5.8 No No
7 empty 2.48 45.6 6.8 No No
8 empty 2.17 51.1 7.6 No No
9 empty 2.81 65.4 5.4 No No
10 empty 2.49 55.3 5.8 No No
3WNY_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 69.5 8.2 No No
2 empty 2.47 58.1 12.9 No No
3 empty 2.74 55.6 6.6 No No
4 empty 2.12 66.3 5.6 No No
1EJM_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.99 64 11.2 No No
2 bound 2.27 57.6 15.5 No No
3 empty 2.55 57.8 12.1 No No
4 bound 2.69 64.9 9.4 No No
5 empty 2.17 51.4 7.1 No No
6 empty 3.23 46.8 7.5 No No
7 empty 2.93 57 5.9 No No
8 empty 1.94 47.1 6.1 No No
9 empty 2.52 58.1 5.6 No No
10 bound 2.45 62.9 5.6 No No
5XX8_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.33 59.3 16.5 No No
2 empty 2.01 69.8 9.6 No No
3 empty 2.45 51.9 13.2 No No
4 empty 2.11 64.2 13.3 No No
5 empty 2.58 60.4 11.3 No No
6 empty 2.97 62.7 8 No No
7 empty 2.24 64.3 6.7 No No
8 empty 1.83 63.4 7.3 No No
9 empty 2.99 68.5 4.9 No No
10 empty 1.98 38 6.2 No No
1BHC_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 65.7 9.8 No No
2 empty 1.82 66.7 9.4 No No
3 empty 2.69 65.6 7.6 No No
4 empty 2.75 50 8.1 No No
5 empty 2.25 67.8 6.8 No No
6 empty 2.3 52 9.1 No No
7 empty 2.64 58.7 6.9 No No
8 empty 3.29 58.3 5.1 No No
9 empty 2.3 48.6 5.9 No No
10 empty 2.44 72.7 0 No No
1OA5_5 Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.56 63.9 12.6 No No
2 empty 2.34 67.6 5.9 No No
3 empty 2.67 60.5 8.9 No No
4 empty 1.7 69.3 7.9 No No
5 empty 1.81 72.4 6 No No
6 empty 2.6 42 6.4 No No
7 empty 2.39 71.9 5.9 No No
8 empty 1.44 73.8 4.7 No No
9 empty 2.83 65.5 5.8 No No
3WNY_F Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.71 70.1 8 No No
2 empty 2.27 65.3 9.9 No No
3 empty 2.01 72.4 0 No No
5XX6_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.31 57.6 14.7 No No
2 empty 1.79 69.3 8.4 No No
3 empty 2.31 61.9 13.7 No No
4 empty 2.5 49.1 10.1 No No
5 empty 2.79 43.2 7 No No
6 empty 2.82 61.9 7.6 No No
7 empty 2.2 49.2 7.6 No No
8 empty 2.56 62.4 6.6 No No
9 empty 1.85 64 7.1 No No
10 empty 2.76 65.2 5.8 No No
3BTE_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 54.9 14.2 No No
2 empty 1.6 65 8.6 No No
3 empty 2.4 62.3 8.3 No No
4 bound 3.11 69.7 8.4 No No
5 empty 1.97 63.8 6 No No
6 empty 1.84 66.7 5.8 No No
7 empty 2.53 62.2 5.8 No No
3GYM_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 58.4 11.8 No No
2 empty 2.13 64.1 15.5 No No
3 empty 2.09 61.7 9.4 No No
4 empty 1.93 60.2 5.6 No No
5 empty 2.61 64.4 0 No No
6 empty 1.78 60.5 6.6 No No
7 empty 2.97 54.7 7.1 No No
1F5R_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.63 57.2 11.6 No No
2 empty 2.5 61.5 13.3 No No
3 empty 2.72 68.2 10.3 No No
4 empty 2.27 63.8 8.1 No No
5 empty 2.99 65.5 6.1 No No
6 empty 2.48 72 5.6 No No
7 empty 2.66 50 5.3 No No
8 empty 1.61 64.2 5.6 No No
2R9P_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.99 58.1 14.7 No No
2 bound 2.15 57.3 13.1 No No
3 empty 1.59 54.9 8.2 No No
4 empty 2.23 57.1 10.1 No No
5 empty 2.64 70.5 7.1 No No
6 empty 2.99 65.6 8.1 No No
7 empty 2.28 67.5 6.9 No No
8 empty 2.23 65.7 0 No No
9 empty 3.24 63 5.1 No No
10 empty 3.29 56.5 6.1 No No
3FP6_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.79 64.5 10.6 No No
2 bound 2.27 54.2 13.3 No No
3 empty 1.6 69.7 8 No No
4 empty 2.38 53.3 8.1 No No
5 empty 2.55 58 7.1 No No
6 empty 2.05 67.9 7.3 No No
7 empty 2.05 52.6 7.4 No No
8 empty 2.51 75 0 No No
9 empty 2.58 62.5 5.4 No No
10 empty 1.18 63.9 5.8 No No
1B0C_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.65 67.9 7.9 No No
2 empty 2.61 59.4 11.4 No No
3 empty 2.31 55.5 6.6 No No
4 empty 1.89 66.7 7.1 No No
5 empty 2.54 56.3 9 No No
6 empty 2.72 54.3 6.4 No No
1BZ5_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.93 60.5 13.2 No No
2 empty 2.52 62.6 11.1 No No
3 empty 1.92 69.7 8.1 No No
4 empty 1.82 70.3 6.8 No No
5 empty 2.31 53.4 8.5 No No
6 empty 1.83 47 5.1 No No
7 empty 1.95 66.7 5.5 No No
8 empty 2.86 59.6 6.3 No No
3BTH_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 57.7 15.6 No No
2 empty 1.72 66.7 7.7 No No
3 bound 2.99 68.8 7.6 No No
4 empty 2.45 63.5 7.4 No No
5 empty 1.43 57.3 5.9 No No
6 empty 2.42 71.6 5.4 No No
7 empty 2.55 59.5 5 No No
3LDM_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.51 70.1 9.6 No No
2 empty 2.96 69.1 7.1 No No
3 empty 2.44 55.4 8.3 No No
4 empty 1.43 65.3 8.4 No No
5 empty 2.73 56.2 5.6 No No
6 empty 3.04 67.3 7 No No
7 empty 2.6 70.9 6.8 No No
8 empty 2.49 54.5 6.9 No No
9 empty 2.72 74.7 0 No No
10 empty 3.17 48.1 5.7 No No
3BTQ_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 55.5 15.5 No No
2 empty 1.64 63.9 8.2 No No
3 bound 2.74 66 9.5 No No
4 empty 2.37 64.2 8.1 No No
5 empty 1.45 61.5 6.2 No No
6 empty 2.55 75.9 5.4 No No
1P2Q_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.74 61.3 12.5 No No
2 bound 2.65 57.2 11.6 No No
3 bound 2.27 62 7.7 No No
4 empty 2.31 63.2 9.3 No No
5 empty 1.83 61 12.4 No No
6 empty 1.03 68 0 No No
7 bound 3.33 60.8 5.7 No No
2HEX_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 64.9 9.7 No No
2 bound 2.71 61.1 11.9 No No
3 empty 1.82 67.6 6.8 No No
4 empty 2.61 62.6 10.5 No No
5 empty 2.52 62.3 7.5 No No
6 empty 2.57 52.4 6.3 No No
7 empty 2.39 64.9 7.2 No No
8 empty 3.03 65.4 5 No No
9 empty 2.57 57.5 7.6 No No
10 empty 3.27 41.2 5.9 No No
2FI5_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.83 59.3 12.2 No No
2 bound 2.18 56.3 11 No No
3 bound 2.55 62.7 12.9 No No
4 bound 2.69 62.6 11.6 No No
5 empty 1.54 67.5 9.8 No No
6 empty 2.21 61.7 10 No No
7 empty 2.1 66.7 5 No No
2TGP_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 65 12.1 No No
2 empty 2.2 58.7 12.8 No No
3 empty 2.82 48.3 9.5 No No
4 empty 2.36 63.5 8.1 No No
5 bound 2.89 65.8 8.4 No No
6 empty .9 64.6 6 No No
7 empty 2.5 71.1 6 No No
8 empty 2.31 63.3 5 No No
1CBW_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.38 65 11 No No
2 empty 1.8 66.2 10.9 No No
3 empty 2.72 59.4 12.2 No No
4 empty 2.09 61.2 8.7 No No
5 empty 2.57 62.8 9.1 No No
6 empty 2.63 72.5 7 No No
7 empty 3.21 60.2 5.7 No No
1D0D_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 56.9 14.3 No No
2 bound 2.69 57.1 14.9 No No
3 empty 1.79 77 8.3 No No
4 empty 2.55 61.3 9 No No
5 empty 1.12 60.7 5.9 No No
6 empty 2.11 100 0 Yes No
7 empty 3.45 47.8 4.7 No No
3WNY_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.75 71.6 8.3 Yes No
2 empty 2.7 54.4 7.7 No No
3 empty 2.57 60.4 5.3 No No
4 empty 2.12 78.4 0 No No
5 empty 2.75 69.1 5.1 No No
4PTI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.29 55.5 17.9 No No
2 empty 1.77 68.6 11.9 No No
3 empty 2.33 63.3 8.9 No No
4 empty 2.5 49.7 9 No No
5 empty 1.65 59.4 6.6 No No
6 empty 3.56 50 5.6 No No
1P2Q_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.65 58.3 12.1 No No
2 bound 2.28 61.3 12.1 No No
3 empty 1.71 73.2 11.5 No No
4 empty 2.42 62.5 9.8 No No
5 empty 1.73 56.7 10.9 No No
3BTM_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 56.8 12.1 No No
2 empty 1.67 64.8 8.3 No No
3 bound 2.52 70.1 10.5 No No
4 empty 1.88 61.1 8.2 No No
5 empty 1.91 60.6 6.5 No No
6 empty 2.38 72.2 5.2 No No
7 empty 1.92 63.1 5.4 No No
4TPI_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 59.8 12.1 No No
2 empty 2.16 58.7 11.2 No No
3 empty 2.31 53.3 13.5 No No
4 empty 2.77 47.2 10 No No
5 empty 2.61 50.8 6.9 No No
6 bound 3.17 65.6 7 No No
7 empty 2.33 70.8 6.4 No No
8 empty 1.32 60 5.1 No No
5XX2_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 57.6 16 No No
2 empty 1.48 62.4 12.2 No No
3 empty 2.7 55.9 13.3 No No
4 bound 2.76 62.9 9.9 No No
5 empty 2.76 58.5 5.5 No No
6 empty 2.75 75.7 0 No No
7 empty 2.23 57 6.1 No No
8 empty 2.13 52 6.3 No No
3FP7_J Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.43 55.1 13.5 No No
2 empty 2.04 64.3 10 No No
3 bound 2.67 54.7 11.6 No No
4 empty 2.3 53.5 7.8 No No
5 empty 2.64 49.4 6.8 No No
6 empty 1.49 65.9 5.8 No No
2FI3_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 61.1 12.2 No No
2 bound 2.11 59.5 12.5 No No
3 bound 2.23 59.1 12.7 No No
4 bound 2.86 59.8 9.4 No No
5 empty 1.78 68.9 9.9 No No
6 empty 2.25 59.1 9 No No
7 empty 2.75 69 5.5 No No
8 empty 2.76 67.6 5 No No
1OA6_5 Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 63.2 12.6 No No
2 empty 2.4 66.9 7.6 No No
3 empty 2.16 79.8 0 No No
4 empty 1.49 72 4.6 No No
5 empty 2.87 65.3 6.7 No No
6 empty 2.94 67.5 5.7 No No
7 empty 1.86 71 5.9 No No
8 empty 1.77 42.5 6.9 No No
9 empty 2.03 96.1 0 Yes No
10 empty 1.57 67.2 4.8 No No
1EAW_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.34 57.3 16.4 No No
2 empty 1.96 65.3 9.1 No No
3 empty 2.11 65.9 6.3 No No
4 empty 2.2 54.2 8.3 No No
5 empty 2.29 69.8 7 No No
6 empty 3.08 50 8.6 No No
7 empty 2.73 67.1 5.8 No No
1AAL_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.83 55.8 11.8 No No
2 bound 2.24 58.6 11.6 No No
3 empty 2.64 60.5 9.7 No No
4 empty 2.21 59.8 12.3 No No
5 empty 2.67 57.8 8.9 No No
6 empty 2.65 48.9 8 No No
7 empty 2.7 55.2 6.8 No No
8 empty 3.34 56.2 5.2 No No
9 empty 2.19 71.2 4.6 No No
5XX6_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.63 66.8 8.8 No No
2 bound 2.79 62.6 10.5 No No
3 bound 2.33 55.5 14.4 No No
4 empty 2.7 68.8 5 No No
5 empty 2.07 61.5 9.1 No No
6 empty 2.46 72.5 0 No No
7 empty 2.83 58.7 7.5 No No
8 empty 2.6 65.8 5.4 No No
1BZX_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.76 66.1 12.1 No No
2 empty 2.32 63 11.4 No No
3 empty 2.18 65.6 14.8 No No
4 empty 2.32 57.4 10.9 No No
5 empty 2.73 55.4 7.5 No No
6 empty 3.21 62.9 5.3 No No
7 empty 2.38 71.4 5.5 No No
8 empty 3 63.8 5.2 No No
9 empty 3.04 59.8 5.6 No No
10 empty 3.55 57.5 5.6 No No
2ZVX_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.74 58.5 13.3 No No
2 empty 1.77 68.8 8.7 No No
3 empty 2.66 64.5 7.8 No No
4 empty 2.54 66.1 6.3 No No
5 empty 2.55 72.2 0 No No
6 empty 2.2 57.8 6.6 No No
1BZ5_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 64.4 8 No No
2 empty 2.76 62.4 10.5 No No
3 empty 2.83 62.4 8.9 No No
4 empty 2.39 57 7.4 No No
5 empty 2.42 75.6 6.5 No No
6 empty 1.83 81.6 0 No No
7 empty 2.26 50.5 6 No No
8 empty 1.73 63.5 0 No No
3P95_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 58.6 9.7 No No
2 empty 2.65 56.8 9.9 No No
3 empty 2.19 60.1 12.7 No No
4 empty 2.59 54.5 13.2 No No
5 empty 1.79 66.4 7.8 No No
6 empty 2.01 65 6.6 No No
7 empty 2.59 69.3 0 No No
5XX4_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 62 13.4 No No
2 empty 1.96 63 11.7 No No
3 bound 2.38 57.1 15.2 No No
4 empty 2.69 60.1 9.3 No No
5 empty 2.85 48.5 9.8 No No
6 empty 2.44 59.3 7.6 No No
7 empty 2.41 55.4 7.6 No No
8 empty 2.25 43 6.9 No No
3TGK_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 58.8 16.4 No No
2 bound 2.69 67.5 9.7 No No
3 empty 1.63 70 7.7 No No
4 empty 2.82 57.5 7.7 No No
5 empty 2.72 52.7 7.1 No No
6 empty 2.01 60.2 5.9 No No
7 empty 2.63 75 0 No No
8 empty 2.77 66.1 5.1 No No
9 empty 1.07 62.3 5.1 No No
2RA3_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 60.8 15.4 No No
2 bound 2.11 57.9 14.4 No No
3 bound 2.73 60.3 12.2 No No
4 empty 2.2 60.1 9.9 No No
5 empty 2.44 67.3 7.3 No No
6 empty 2.66 66 6 No No
7 empty 1.35 54.7 5.7 No No
8 empty 3.09 72 0 No No
9 empty 3.53 63.3 6.3 No No
3LDI_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.52 60.2 9.7 No No
2 empty 2.55 60.7 10.5 No No
3 empty 1.97 59.2 10.4 No No
4 empty 2.82 55 7.3 No No
5 empty 2 70.5 5.7 No No
6 bound 3.11 59.5 5.3 No No
7 empty 2.65 51.7 6.5 No No
8 empty 1.77 63 5 No No
9 empty 1.43 69.7 5.5 No No
3OTJ_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 59.5 12.4 No No
2 bound 2.15 57.9 14.9 No No
3 bound 2.75 66.1 8 No No
4 empty 2.23 61.1 9.1 No No
5 empty 2.91 60.8 7.1 No No
6 empty 2.53 69.7 6.5 No No
7 empty 1.6 66.3 5.8 No No
8 empty 3.13 42.4 7.4 No No
9 empty 2.91 67.4 5.6 No No
10 empty 2.92 59.2 5.8 No No
2R9P_G Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.58 53.8 12.3 No No
2 bound 2.25 57.2 8.7 No No
3 bound 2.89 69.3 8.9 No No
4 empty 2.47 67.7 9.6 No No
5 empty 2.49 64.4 7.1 No No
6 empty 2.16 58 10.4 No No
7 empty 1.37 57.6 5.6 No No
8 empty 2.37 68.5 8.6 No No
9 empty 3.01 63.6 4.5 No No
10 empty 1.91 63.5 5.1 No No
3LDI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.75 61.2 10 No No
2 bound 2.71 58.1 11.3 No No
3 empty 2.46 65.5 10.7 No No
4 empty 2.38 68.8 6.1 No No
5 bound 2.17 51.3 9.6 No No
6 empty 1.52 64.8 9 No No
7 empty 2.36 76.6 4.8 No No
8 empty 1.95 60.5 5.2 No No
9 empty 1.93 53.1 5.6 No No
2FI4_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 61.4 12.1 No No
2 bound 2.12 58 10.6 No No
3 bound 2.29 63.7 12.1 No No
4 bound 2.84 59.8 9.4 No No
5 empty 1.78 65.4 10.7 No No
6 empty 2.16 60.3 10.4 No No
7 empty 2.74 65.7 5.5 No No
8 empty 2.37 61.4 5.5 No No
2R9P_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 57.4 12.6 No No
2 bound 2.79 58.4 11.8 No No
3 bound 2.26 56.3 14.4 No No
4 empty 2.5 57.7 10.6 No No
5 empty 2.44 66.1 7.5 No No
6 empty 2.26 69.2 6.9 No No
7 empty 1.25 62.3 5.8 No No
8 empty 2.9 73.7 4.4 No No
1BTH_Q Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.56 63.3 12 No No
2 empty 2.17 57.8 12.1 No No
3 empty 2.77 66.3 9.8 No No
4 empty 2.68 65.2 6.1 No No
5 empty 3.02 52.6 7.4 No No
6 empty 2.38 41.5 8.4 No No
7 empty 1.83 65.2 5.4 No No
8 empty 1.97 51.1 6.5 No No
9 empty 2.95 52.4 6.6 No No
10 empty 2.24 59.3 7.2 No No
4BNR_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 58.3 12.7 No No
2 empty 2.14 58.2 15.7 No No
3 empty 1.95 53.6 7.8 No No
4 bound 2.72 61.3 9.5 No No
5 empty 2.59 61.7 5.6 No No
6 empty 2.54 55.8 5.7 No No
7 empty 2.67 54.7 7.5 No No
8 empty 1.78 62.5 6.6 No No
9 empty 2.78 66.7 0 No No
10 empty 3.2 66.1 4.4 No No
2HEX_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.51 63.6 9.6 No No
2 bound 2.97 64.7 10.9 No No
3 empty 2.63 67.7 10 No No
4 empty 1.75 57.3 5.9 No No
5 empty 2.21 63.5 6.2 No No
6 empty 2.14 61.5 5.4 No No
7 empty 2.11 76 0 No No
8 empty 2.68 57.8 6.1 No No
9 empty 2.82 72.3 4.5 No No
3BTT_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 59.7 15.5 No No
2 empty 1.67 63.8 8 No No
3 bound 3.21 60.4 7.5 No No
4 empty 1.4 61.3 6.3 No No
5 empty 2.54 59.7 5.8 No No
6 empty 2.4 66.2 5.7 No No
1LD5_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.69 67.3 12.5 No No
2 empty 2.5 63.1 14.1 No No
3 empty 2.93 59.6 13.3 No No
4 empty 1.7 53.4 7.7 No No
5 empty 3.25 62.9 7.4 No No
6 empty 2.71 58.5 6.6 No No
7 empty 2.31 71.4 5.7 No No
8 empty 2.09 50.4 7.5 No No
9 empty 3.52 71.6 5.5 No No
10 empty 2.57 48.9 6 No No
5JB5_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.57 69.1 7.9 No No
2 empty 2.72 51.9 8.5 No No
3 empty 2.72 62 6.5 No No
4 empty 2.05 68.9 6.7 No No
2HEX_E Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 64 11.7 No No
2 empty 2.07 57.6 11.3 No No
3 bound 2.65 68 8.9 No No
4 empty 2.67 63.8 9.1 No No
5 empty 1.89 53.8 7 No No
6 empty 2.49 73.1 5.4 No No
7 empty 3.12 73 5.5 No No
8 empty 3.53 51.8 5.7 No No
2TPI_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 57.7 12.4 No No
2 empty 2.1 55.7 9.5 No No
3 empty 2.69 67.7 7.6 No No
4 empty 1.97 59.2 7.3 No No
5 empty 3.21 52.6 7.4 No No
6 empty 1.56 62 5.3 No No
1P2M_D Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.99 63.1 12.1 No No
2 empty 2.72 62 10.7 No No
3 bound 2.35 60.9 11.5 No No
4 empty 2.38 61.9 9.8 No No
5 empty 1.69 67.6 4.9 No No
5PTI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 57.9 12.3 No No
2 bound 2.23 57.3 14.5 No No
3 empty 2.58 61.8 6.9 No No
4 empty 3.1 62.4 7.5 No No
5 empty 1.95 53.5 6.6 No No
6 empty 1.65 66.1 5.5 No No
7 empty 3.07 58.8 6.4 No No
8 empty 2.24 73.5 4.4 No No
9 empty 2.91 73.2 0 No No
1BZ5_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.76 56.5 11.2 No No
2 empty 1.73 70.6 7.2 No No
3 empty 2.68 64.9 7.1 No No
4 empty 2.42 50 7 No No
5 empty 2.23 70.6 4.5 No No
6 empty 1.87 55.1 5.5 No No
7 empty 2.78 54.1 5.8 No No
8 empty 1.82 71.6 4.3 No No
9 empty 1.46 62.1 5.6 No No
1B0C_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.63 64.6 8.2 No No
2 empty 2.12 52.8 6.8 No No
3 empty 2.28 61.8 5.4 No No
4 empty 1.83 66.7 6.6 No No
1P2J_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.59 60.2 12.3 No No
2 bound 2.76 58.8 11.2 No No
3 bound 2.14 62.3 9.9 No No
4 empty 1.92 59.1 7 No No
5 empty 2.84 69.5 5.8 No No
6 empty 2.82 55.9 5.4 No No
7 empty 2.22 61 6 No No
1JV8_A Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.52 62.3 12.4 No No
2 empty 1.62 72.5 0 Yes No
3 empty 2.81 57 6.9 No No
4 empty .76 68.9 6.9 No No
5 empty 2.67 67.4 6.3 No No
6 empty 2.91 53.3 7.9 No No
7 empty 3.11 62 6 No No
8 empty 2.42 77 0 No No
9 empty 2.36 61.4 4.3 No No
5XX5_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.56 55.5 20.9 No No
2 empty 2.58 55.2 15.3 No No
3 empty 1.94 70 9.4 No No
4 bound 2.23 60.4 12.5 No No
5 empty 3.13 67.6 5.2 No No
6 empty 2.99 68.1 4.9 No No
5JB6_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 71.5 7.8 Yes No
2 bound 2.75 64.4 8.8 No No
3 empty 2.49 68.8 5.5 No No
3LDI_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.65 69.1 8.2 No No
2 empty 2.6 65.7 9.4 No No
3 bound 2.34 55 10 No No
4 empty 1.23 67 4.9 No No
5 empty 2.93 60.7 7.9 No No
6 empty 2.14 78.3 0 No No
7 empty 2.86 65 6.4 No No
8 empty 2.59 47.2 6 No No
9 bound 2.86 59.7 5.4 No No
3LDJ_C Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 52.4 12.9 No No
2 empty 2.4 62 8.7 No No
3 empty 2.55 62.5 7.8 No No
4 empty 1.8 63.5 6.9 No No
1P2M_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.68 66 11.3 No No
2 bound 2.72 56 11.5 No No
3 bound 2.3 59.2 12.5 No No
4 empty 2.44 62.9 8.8 No No
5 empty 3.78 73 4.7 No No
1BPT_A Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.84 65.3 11.5 No No
2 empty 2.75 59.6 8.8 No No
3 empty 2.27 60.5 11.3 No No
4 empty 3.07 53.1 7.1 No No
5 empty 2.43 97.6 0 Yes No
6 empty 2.06 74 5 No No
7 empty 3.03 54.1 5 No No
1P2N_B Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.66 64.8 11.9 No No
2 bound 2.66 56.1 12.1 No No
3 bound 2.29 60.8 15 No No
4 empty 2.4 63.8 9.7 No No
5 empty 2.42 60.8 5.9 No No
6 empty 3.34 80.3 0 No No
7 empty 1.45 73.5 0 No No
8 empty 1.77 42.6 5.5 No No
1UUB_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.37 56.7 8.3 No No
2 empty 1.83 61.3 6.5 No No
3 empty 2.62 54 7.6 No No
4 empty 2.92 63.3 6.7 No No
5 empty 2.33 72.3 5.2 No No
6 empty 2.52 57 6.3 No No
7 empty 2.66 64.3 5.1 No No
8 empty 1.07 61.1 5 No No
1BHC_F Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.42 63.9 10.8 No No
2 empty 1.63 70.9 6.9 No No
3 empty 2.71 68 7.5 No No
4 empty 2.56 53.6 9.5 No No
5 empty 2.53 53.7 9.6 No No
6 empty 2.49 59 5.6 No No
7 empty 2.35 66.7 6.6 No No
8 empty 3.62 52.2 5.5 No No
9 empty 2.32 47 5.2 No No
10 bound 2.59 53.7 6.9 No No
1FY8_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.68 59.2 11 No No
2 bound 3 64.6 10.3 No No
3 empty 2.36 62 10.2 No No
4 empty 2.67 61.3 9.9 No No
5 empty 2.19 58.9 10.3 No No
6 empty 2.44 71.3 0 No No
7 empty 1.03 63.3 4.7 No No
8 bound 2.75 48.1 6.9 No No
5JB4_B Pancreatic trypsin inhibitor Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 72.4 7.7 Yes No
2 bound 2.75 65.9 8 No No
3 empty 2.51 74.7 0 No No
3WNY_H Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 57.6 12.6 No No
2 empty 2.65 65 11.9 No No
3 empty 2.09 61 7.7 No No
4 empty 2.48 70.8 5.8 No No
4DG4_H Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.74 62.5 11.4 No No
2 bound 2.79 56.8 11.9 No No
3 bound 2.3 56.6 14.3 No No
4 empty 2.37 66.3 9.2 No No
5 empty 2.57 54 8.8 No No
6 empty 2.12 60.6 7.2 No No
7 empty .96 59.5 6.5 No No
8 empty 2.72 69.3 0 No No
9 empty 1.81 61.2 5.9 No No
10 empty 2.73 60 4.2 No No
4WWY_I Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.59 58.9 12.1 No No
2 bound 2.78 59.4 12.3 No No
3 empty 2.19 66 13.2 No No
4 bound 2.36 59 11.9 No No
5 empty 2.43 56.2 9.2 No No
6 empty 2.29 61.7 10.1 No No
7 empty 2.46 61.7 7.1 No No
8 empty 2.42 62 7.7 No No
9 empty 1.98 68.3 4.3 No No
9PTI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.19 58.9 15.9 No No
2 empty 1.63 63.6 9.2 No No
3 bound 2.33 59.1 11.4 No No
4 empty 2.32 68.2 7 No No
5 empty 2.77 64.6 10 No No
6 empty 3.09 57 6.4 No No
7 empty 2.16 77 0 No No
1BHC_H Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.43 62.3 9.5 No No
2 empty 1.84 70 8.4 No No
3 empty 2.78 66.7 7.7 No No
4 empty 2.42 62.5 6.4 No No
5 empty 2.35 53.2 9.2 No No
6 empty 2.79 59.1 7 No No
7 empty 2.6 56.5 6.4 No No
8 empty 2.94 52.7 6.3 No No
9 empty 2.29 44.3 5.9 No No
10 empty 3.08 48.3 6.2 No No
6PTI_A Pancreatic trypsin inhibitor No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.65 58.6 19.7 No No
2 empty 1.71 59.6 12 No No
3 empty 2.58 59.4 7.8 No No
4 empty 1.95 57.7 9.1 No No
5 empty 2.71 50.5 6.2 No No
6 empty 2.52 75.5 0 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed137
Domains assessed as druggable using the strict criteria2
Domains assessed as druggable using the relaxed criteria5

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1AAL_B (44473) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.6Å No No
1AAL_A (44472) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.6Å No No
1B0C_A (44518) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1B0C_B (44519) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1B0C_D (44521) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1B0C_E (44522) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1B0C_C (44520) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1BHC_E (44527) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å Yes No
1BHC_F (44528) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_G (44529) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_H (44530) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_I (44531) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_A (44523) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_J (44532) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_D (44526) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BHC_B (44524) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å Yes No
1BHC_C (44525) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.63Å No No
1BPI_A (44468) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.09Å No No
1BPT_A (44495) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2Å No No
1BRB_I (44500) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
1BTH_P (44508) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.3Å No No
1BTH_Q (44509) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.3Å No No
1BTI_A (44498) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.2Å No No
1BZ5_C (44512) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.58Å No No
1BZ5_B (44511) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.58Å No No
1BZ5_A (44510) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.58Å No No
1BZ5_D (44513) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.58Å No No
1BZ5_E (44514) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.58Å No No
1BZX_I (44501) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
1CBW_D (44516) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.5Å No No
1CBW_I (44517) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.5Å No No
1CO7_I (76136) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
1D0D_B (44475) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.62Å No No
1EAW_D (64888) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.93Å No No
1EAW_B (64886) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.93Å No No
1EJM_B (59425) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
1EJM_F (59429) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
1EJM_D (59427) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
1F5R_I (59655) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.65Å No No
1F7Z_I (59682) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.55Å No No
1FAK_I (44515) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
1FAN_A (44484) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2Å No No
1FY8_I (44491) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.7Å No No
1G6X_A (60320) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins .86Å No No
1JV8_A (63305) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins Yes No
1JV9_A (63306) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No Yes
1K6U_A (68233) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1Å No No
1LD5_A (77902) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1LD6_A (77903) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1MTN_H (44535) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1MTN_D (44534) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
1NAG_A (44477) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
1OA5_5 (92696) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1OA6_5 (92697) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1P2I_I (93934) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.65Å No No
1P2J_I (93936) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.35Å No No
1P2K_I (93938) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.6Å No No
1P2M_B (93941) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
1P2M_D (93943) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
1P2N_B (93945) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
1P2N_D (93947) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
1P2O_B (93949) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2Å No No
1P2O_D (93951) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2Å No No
1P2Q_B (93953) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
1P2Q_D (93955) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
1PIT_A (44536) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1QLQ_A (44470) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.42Å No No
1T7C_B (119163) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
1T7C_D (119165) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
1T8L_B (119176) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
1T8L_D (119178) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
1T8M_D (119182) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
1T8M_B (119180) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
1T8N_B (119184) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
1T8N_D (119186) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
1T8O_B (119188) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.7Å No No
1T8O_D (119190) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.7Å No No
1TPA_I (44486) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
1UUA_A (100003) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1UUB_A (100004) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins No No
1YKT_B (123564) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.7Å No No
2FI3_I (145168) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.56Å No No
2FI4_I (145169) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.58Å No No
2FI5_I (3090230) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.58Å No No
2FTL_I (134074) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.6Å No No
2FTM_B (134075) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.65Å No No
2HEX_D (44505) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
2HEX_E (44506) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
2HEX_B (44503) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
2HEX_A (44502) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
2HEX_C (44504) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
2IJO_I (137480) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.3Å No No
2KAI_I (44533) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.5Å No No
2PTC_I (44490) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
2R9P_E (151798) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.4Å No No
2R9P_F (151799) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.4Å No No
2R9P_I (151801) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.4Å No No
2R9P_G (151800) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.4Å No No
2RA3_C (151817) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.46Å No No
2RA3_I (151818) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.46Å No No
2TGP_I (44494) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
2TPI_I (44497) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.1Å No No
2ZJX_A (4123762) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins (Homo Multimer) 1.09Å No No
2ZJX_B (4123762) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins (Homo Multimer) 1.09Å No No
2ZJX_A (3290372) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.09Å No No
2ZVX_A (3290960) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.09Å No No
2ZVX_A (4067085) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins (Homo Multimer) 1.09Å Yes Yes
2ZVX_B (4067085) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins (Homo Multimer) 1.09Å Yes Yes
3BTD_I (44485) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
3BTE_I (44489) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
3BTF_I (44482) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
3BTG_I (44492) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
3BTH_I (44479) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.75Å No No
3BTK_I (44483) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.85Å No No
3BTM_I (44481) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
3BTQ_I (44487) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
3BTT_I (44488) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
3BTW_I (44496) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.05Å No No
3FP6_I (3410727) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.49Å No No
3FP7_J (3410729) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.46Å No No
3FP8_I (3410731) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.46Å No No
3GYM_I (3440730) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.8Å No No
3LDI_A (3530088) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.2Å No No
3LDJ_A (3530089) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.5Å No No
3LDM_A (3530095) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.6Å No No
3OTJ_I (3650860) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.6Å No No
3P92_E (3660574) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.599Å No No
3P95_E (3660577) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.299Å No No
3TGI_I (44480) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å No No
3TGJ_I (44507) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.2Å No No
3TGK_I (63339) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.7Å No No
3TPI_I (44493) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.9Å No No
4PTI_A (44471) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.5Å No No
4TPI_I (44499) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 2.2Å No No
5PTI_A (44467) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1Å No No
6PTI_A (44474) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.7Å No No
7PTI_A (44476) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.6Å No No
8PTI_A (44478) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.8Å Yes No
9PTI_A (44469) Pancreatic trypsin inhibitor BPTI-like, BPTI-like, Small Kunitz-type inhibitors & BPTI-like toxins 1.22Å No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score