Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(P00974) - Overview - Molecular Target Synopsis

Protein


, Pancreatic trypsin inhibitor
UniProt P00974

Also Known as BPT1_BOVIN

Inhibits trypsin, kallikrein, chymotrypsin, and plasmin.

5YVU
CRYSTAL STRUCTURES OF UNLINKED FULL LENGTH NS3 FROM DENGUE VIRUS PROVIDE INSIGHTS INTO DYNAMICS OF PROTEASE DOMAIN
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
100P00974-1

Sub-cellular localization


UniProt: is active in the following subcellular-locations: secreted.
GO terms: is active in the following subcellular-locations: extracellular space, serine protease inhibitor complex.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
120 structures (208 chains) solved
8 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


has been screened with compounds ( bioactivities). (see details)