Molecular Target Synopsis
Overview
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Drugs and Clinical Candidates
Druggability
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RNAi
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npr (P00800) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/07/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 23/07/2019)


Chains assessed188
Chains with at least one site assessed as druggable using the strict criteria6
Chains with at least one site assessed as druggable using the relaxed criteria182


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
5N3V_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 68.2 32.7 Yes No
2 empty 2.26 70.3 22.5 No No
3 empty 2.18 60.3 24.5 No No
4 empty 2.26 65.8 22.3 No No
5 empty 2.43 63.7 18.1 No No
6 empty 1.99 60.9 22.1 No No
7 empty 2.49 69.4 12.3 No No
8 bound 2.32 58.4 12.3 No No
9 empty 2.42 64.9 9.5 No No
10 empty 2.63 73.3 10 No No
5TAE_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 66.8 35.2 Yes No
2 empty 2.56 64.8 31.2 No No
3 empty 2.3 69.6 24.5 No No
4 empty 2.24 59.3 20.4 No No
5 empty 2.05 64.8 14.5 No No
6 empty 2.04 61.3 18.2 No No
7 empty 2.47 57.4 13.1 No No
8 empty 2.62 76.8 9.1 No No
9 empty 2.53 64.6 9.1 No No
10 empty 2.3 59.2 11.9 No No
1LND_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 69.6 29 Yes No
2 empty 2.16 62.7 18.7 No No
3 empty 2.44 60.1 16.7 No No
4 empty 2.1 64.7 18 No No
5 empty 1.93 60.7 18.4 No No
6 empty 2.14 69.3 17.2 No No
7 empty 2.47 73.4 11.8 No No
8 empty 2.85 70.5 15.4 No No
9 empty 2.57 58 11.6 No No
10 empty 2.06 59.4 11.9 No No
5TAD_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.75 66.5 35.7 Yes No
2 empty 2.33 68.1 30.2 No No
3 empty 2.63 66.4 31.1 No No
4 empty 1.92 63.9 14.5 No No
5 empty 2.13 64.1 17.9 No No
6 empty 2.82 72.9 15.1 No No
7 empty 2.36 57.4 16.6 No No
8 empty 2.48 66.8 10.3 No No
9 empty 2.65 68.9 6.9 No No
10 empty 2.28 60.8 12.7 No No
6D5N_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 67.9 35.9 Yes No
2 empty 2.21 62.2 18.8 No No
3 bound 1.96 65.8 15.8 No No
4 empty 2.01 59.8 23.8 No No
5 empty 2.26 67.4 17.7 No No
6 empty 2.46 63.5 18.1 No No
7 empty 2.42 55 13.7 No No
8 empty 2 77.9 11.2 No No
9 empty 2.57 71.2 10.3 No No
10 empty 2.62 68 6.8 No No
5MNR_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 68.3 32.6 Yes No
2 empty 2.38 71.9 20.6 No No
3 empty 2.2 61.2 18.7 No No
4 empty 2.5 63 16.7 No No
5 empty 2.2 64.3 19.8 No No
6 empty 1.91 61.1 21.6 No No
7 empty 2.46 71.2 12.3 No No
8 bound 2.21 56.9 11.3 No No
9 empty 2.46 64.7 12.1 No No
10 empty 2.57 71.3 10.3 No No
3T2I_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 65.2 33 Yes No
2 empty 2.08 64.5 15.2 No No
3 empty 1.86 63.7 17.6 No No
4 empty 2.57 63.6 19 No No
5 empty 2.01 61.9 18.8 No No
6 bound 2.18 71.3 11.2 No No
7 empty 2.38 72.2 10 No No
8 empty 2.31 54.3 13.3 No No
9 empty 2.33 64.9 14.5 No No
10 empty 2.68 72.6 8.2 No No
5N2X_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 67.3 32.7 Yes No
2 empty 2.31 69.6 21.3 No No
3 empty 2.2 60.4 17.9 No No
4 empty 2.18 64 21.9 No No
5 empty 2.39 65.4 15.6 No No
6 empty 1.95 60.9 21.6 No No
7 empty 2.38 70 12.7 No No
8 bound 2.22 57.5 11.3 No No
9 empty 2.46 64.1 11.8 No No
10 empty 2.36 75 10.8 No No
6D5S_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 71.6 23.1 Yes No
2 empty 2.24 62.1 18.5 No No
3 empty 2.12 68.3 14 No No
4 empty 1.97 60.4 24.3 No No
5 empty 2.45 62.8 16.3 No No
6 empty 2.18 68.8 12 No No
7 empty 2.22 53.7 12.4 No No
8 empty 2.44 69.3 12.4 No No
9 empty 2.12 76.5 11.4 No No
10 empty 2.52 68.4 9.3 No No
1TMN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 69 35.3 Yes No
2 empty 2.25 62.8 18 No No
3 empty 2.31 66.7 21.8 No No
4 empty 2.08 66.8 15.1 No No
5 empty 2.48 60.8 17.1 No No
6 empty 2.17 64.6 20 No No
7 empty 2.45 75.1 11.3 No No
8 empty 2.36 58.2 16.4 No No
9 empty 2.18 60.4 17.2 No No
10 empty 2.49 71.5 11.2 No No
3ZI6_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 69.9 30.6 Yes No
2 empty 2.23 67.1 21.1 No No
3 empty 1.94 64.4 16.4 No No
4 empty 2.04 63.7 20.8 No No
5 empty 2.48 64.2 16.6 No No
6 empty 2.28 71.1 14.3 No No
7 empty 2.45 69.8 14.9 No No
8 empty 2.75 73.4 8.6 No No
9 empty 2.43 62.3 7.9 No No
10 empty 2.41 67.6 7.6 No No
3MS3_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.81 67.9 31.1 Yes No
2 empty 2.16 56.4 19.5 No No
3 empty 2.11 60.5 18.4 No No
4 empty 1.74 61.6 15.3 No No
5 empty 2.33 58.5 16.4 No No
6 empty 1.9 54.9 16 No No
7 empty 2.28 62.6 13.4 No No
8 bound 2.12 54 11.4 No No
9 empty 2.69 66.8 9.3 No No
10 bound 2.52 67.2 9.9 No No
2TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 69.4 30.1 Yes No
2 empty 2.13 64.3 32.3 No No
3 empty 2.41 60.2 18.3 No No
4 empty 2.04 65.4 21.9 No No
5 empty 1.96 60.9 20 No No
6 empty 2.38 69.8 15.2 No No
7 empty 2.52 59.4 11.4 No No
8 empty 2.59 72 8.3 No No
9 empty 2.41 62.7 10.2 No No
10 empty 2.38 63.8 8.8 No No
6FJ2_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 69 30.7 Yes No
2 empty 2.25 57.7 18.7 No No
3 bound 1.86 66.1 16 No No
4 empty 2.33 60.7 15.7 No No
5 empty 1.9 57.3 18.3 No No
6 empty 2.37 64.1 13.6 No No
7 empty 2.01 60.5 13.2 No No
8 empty 2.41 49.4 9.5 No No
9 empty 2.27 55.1 9.7 No No
10 empty 2.63 76.2 8.5 No No
5L41_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 62.5 30 Yes No
2 empty 2.24 64.6 20.7 No No
3 empty 2.19 57.9 19.8 No No
4 empty 2.51 59.9 17.3 No No
5 empty 2.12 63.1 20.2 No No
6 empty 1.86 53.1 16.1 No No
7 empty 2.32 65.2 11.6 No No
8 bound 2.12 56.6 11.8 No No
9 bound 2.06 98.8 0 Yes No
10 empty 2.44 67.9 10.4 No No
4MZN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 62.7 28 Yes No
2 empty 2.13 59.5 19 No No
3 empty 2.09 63.8 18.7 No No
4 empty 2.43 60.8 17.3 No No
5 empty 1.89 56.4 16.1 No No
6 empty 2.24 73.9 11.5 No No
7 bound 2.11 52.8 11.7 No No
8 bound 2.16 96.1 0 Yes No
9 empty 2.31 61.6 8.9 No No
10 empty 2.27 60.2 10.5 No No
5UN3_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 66.4 27.9 Yes No
2 empty 2.19 61.7 17.4 No No
3 empty 2.3 60.6 20.2 No No
4 empty 2.17 66.1 22.4 No No
5 empty 1.95 65.5 20.7 No No
6 empty 2.01 60.5 22.1 No No
7 bound 2.29 71.6 13.7 No No
8 bound 2.74 66.4 14.9 No No
9 empty 2.39 57.4 16.8 No No
10 empty 2.25 62.1 9.1 No No
1KL6_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 70 29.5 Yes No
2 empty 2.14 61 19.9 No No
3 empty 2.45 60.4 17.4 No No
4 empty 2.3 65 21.4 No No
5 empty 2.02 65.4 19.4 No No
6 empty 2.08 64.7 17 No No
7 empty 2.48 71.8 15.7 No No
8 empty 2.07 57.5 17.3 No No
9 empty 2.38 56.7 13.4 No No
10 empty 2.99 72.2 7.2 No No
6D5T_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 70.2 30.8 Yes No
2 empty 2.18 61.1 16.9 No No
3 empty 2.12 67.9 20.7 No No
4 empty 2.49 59.3 19.1 No No
5 empty 2.02 60.9 21.3 No No
6 empty 2.2 70.8 14.4 No No
7 empty 2.33 69.2 10.4 No No
8 empty 2.51 55.5 14.3 No No
9 empty 2.37 62.7 12.4 No No
10 empty 2.58 69.9 8.8 No No
1LNF_E Thermolysin No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 70.3 23 No No
2 empty 2.17 62.9 18.6 No No
3 empty 2.41 61.4 16.8 No No
4 empty 2.06 65.4 16.8 No No
5 empty 1.89 61.3 19.1 No No
6 empty 2.12 68.5 19.1 No No
7 empty 2.44 69.4 17 No No
8 empty 2.86 70.8 8.9 No No
9 empty 2.55 57.2 11.6 No No
10 empty 2.02 58.1 11.9 No No
3QH5_A Thermolysin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.74 69.9 25.7 Yes Yes
2 empty 2.24 58.5 19.7 No No
3 bound 2.12 64.2 15.3 No No
4 empty 2.2 58.7 14.3 No No
5 empty 1.74 55.3 16.8 No No
6 empty 2.25 67.2 11.5 No No
7 empty 2.49 63.4 12 No No
8 bound 2.19 53.5 10.9 No No
9 empty 2.52 71.1 8.7 No No
10 empty 2.17 56.7 9.7 No No
5N3Y_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 68.8 30.2 Yes No
2 empty 2.28 70.9 20.6 No No
3 empty 2.29 60.9 18.6 No No
4 empty 2.35 66.5 15.9 No No
5 bound 2.21 65.7 19.8 No No
6 empty 1.96 60.4 22.4 No No
7 empty 2.38 69.1 14.9 No No
8 bound 2.21 58.4 11.3 No No
9 empty 2.45 63.8 10.2 No No
10 empty 2.29 73.2 11.9 No No
5FXN_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 68.5 28.1 Yes No
2 empty 2.22 60.4 18.1 No No
3 empty 2.16 64.1 17.8 No No
4 empty 1.93 63.3 21.8 No No
5 empty 2.54 64.2 16.4 No No
6 empty 2.27 71.5 16.5 No No
7 empty 2.37 57.6 17.6 No No
8 empty 2.37 66.9 13 No No
9 empty 2.59 71.4 11.4 No No
10 empty 2.53 65.4 14.3 No No
1Z9G_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.83 71.4 32.7 Yes No
2 empty 2.22 68.5 22 No No
3 empty 2.23 65 16.4 No No
4 empty 2.08 64.3 17.7 No No
5 empty 2.01 62.8 16.7 No No
6 empty 2.46 61.6 16.6 No No
7 empty 2.46 73.5 10.8 No No
8 empty 2.45 60.9 16.2 No No
9 empty 2.12 58.8 10.7 No No
10 empty 2.51 65.1 9.2 No No
5TAJ_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 70.7 24.4 Yes No
2 empty 2.24 62.4 19.6 No No
3 empty 2.21 66 21.8 No No
4 empty 2.09 65.3 13.9 No No
5 empty 2.43 57.4 18.3 No No
6 empty 2.11 62.7 20.7 No No
7 empty 2.02 75.2 9.3 No No
8 empty 2.95 73.2 8.6 No No
9 empty 2.81 65.1 10.9 No No
10 empty 2.55 60.2 10 No No
5TAK_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.84 68.8 25.3 Yes No
2 empty 2.09 63.3 19.8 No No
3 empty 2.46 65.3 15 No No
4 empty 1.92 63.4 18.9 No No
5 empty 1.97 61.9 19.2 No No
6 empty 2.07 72.5 11.6 No No
7 empty 2.54 68.3 10.8 No No
8 empty 2.38 57.6 16.7 No No
9 empty 2.33 62.6 12.8 No No
10 empty 2.64 73.6 9.2 No No
3T87_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 63.4 28.7 Yes No
2 empty 2.24 60.1 19.8 No No
3 empty 1.86 63.3 19.7 No No
4 empty 2.33 60.9 15.9 No No
5 empty 1.89 56.6 16.5 No No
6 empty 2.21 69.7 11.6 No No
7 empty 2.34 63.9 11.6 No No
8 bound 2.11 55.5 11.8 No No
9 bound 2.1 98.2 0 Yes No
10 empty 2.22 57.8 9.5 No No
4OW3_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.81 69.8 29.9 Yes No
2 empty 2.23 64.4 22.9 No No
3 empty 2.47 58.6 19.4 No No
4 empty 2.09 62.9 17.8 No No
5 empty 2.03 63.1 17.3 No No
6 empty 2.35 56 16.3 No No
7 empty 2.39 74.1 10.8 No No
8 empty 2.46 67.1 9 No No
9 empty 2.24 72.6 12.7 No No
10 empty 1.98 52.6 11.6 No No
1FJW_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 69.7 29.4 Yes No
2 empty 2.21 62.8 21.8 No No
3 empty 2.41 61.7 19.7 No No
4 empty 1.96 61.9 17.2 No No
5 empty 2.03 65.3 14.3 No No
6 empty 2.37 63 21.1 No No
7 empty 2.39 70 15.4 No No
8 empty 2.81 65.1 12.2 No No
9 empty 2.48 59.7 10.7 No No
10 empty 2.35 66.3 11.9 No No
3DNZ_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 68.2 34.3 Yes No
2 empty 2.39 62.7 19.1 No No
3 empty 2.17 59.7 19.4 No No
4 empty 2.26 67.4 21.4 No No
5 empty 1.99 59.7 21 No No
6 empty 2.08 64.7 13.6 No No
7 empty 2.39 71.1 14.5 No No
8 empty 2.89 75.3 10.3 No No
9 empty 2.47 59 12.4 No No
10 empty 2.53 63.7 8.9 No No
6TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 66.3 28.9 Yes No
2 empty 2.07 59.8 19 No No
3 empty 2.38 61.7 17.3 No No
4 empty 2.02 66.7 16.8 No No
5 empty 1.91 54.9 16.4 No No
6 empty 2.1 56 17.5 No No
7 empty 2.06 73.3 9.1 No No
8 empty 2.44 70 9.2 No No
9 empty 2.4 58 10.8 No No
10 empty 2.31 64.1 8.8 No No
5JSS_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 60.3 29.5 Yes No
2 empty 2.2 60 19.8 No No
3 empty 2.24 64.2 21.4 No No
4 empty 1.94 62.1 18.8 No No
5 empty 2.4 60.2 17.3 No No
6 empty 1.9 55.7 16.3 No No
7 bound 2.11 54.8 11.8 No No
8 bound 2.05 98.9 0 Yes No
9 empty 2.26 68.1 12.2 No No
10 empty 2.46 66.5 9.8 No No
3FXS_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 66.3 30.6 Yes No
2 empty 2.37 71.5 21.9 No No
3 empty 2.21 62.6 20.9 No No
4 empty 2.25 64.4 18.7 No No
5 empty 1.91 59.9 22.6 No No
6 empty 2.36 62.4 13.9 No No
7 empty 2.35 67.4 13.5 No No
8 empty 2.38 55.4 13 No No
9 empty 2.25 58.8 14.2 No No
10 empty 2.32 65.1 11.8 No No
3TMN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 69.1 29.2 Yes No
2 empty 2.51 66.1 26 No No
3 empty 2.27 66.5 24.5 No No
4 empty 2.26 63.2 17.1 No No
5 empty 2.06 65.7 15 No No
6 empty 1.98 65 17 No No
7 empty 2.87 68.9 14.6 No No
8 empty 2.43 56.9 11.5 No No
9 empty 2.5 66.5 9.2 No No
10 empty 2.09 67.6 8.4 No No
4H57_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 67.9 30.2 Yes No
2 empty 2.35 72.4 24.1 No No
3 empty 2.17 61 18.8 No No
4 empty 2.14 65.4 22.4 No No
5 empty 2.31 62.4 16.5 No No
6 empty 2.18 64.8 19 No No
7 empty 2.3 71.6 13.9 No No
8 bound 2.18 59 10.8 No No
9 empty 2.66 63.8 10.6 No No
10 empty 2.5 71.8 11.6 No No
8TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.81 68.2 25.9 Yes No
2 empty 2.38 62.4 19.6 No No
3 empty 2.22 62.8 19.4 No No
4 empty 2.09 65.8 22.8 No No
5 empty 1.95 60.6 21.1 No No
6 empty 2.01 65.8 17.1 No No
7 empty 2.04 82.7 8.6 No No
8 empty 2.59 52.8 10.9 No No
9 empty 2.54 70.3 9.8 No No
10 empty 2.32 67.8 7.8 No No
4MXJ_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 63.9 27.1 Yes No
2 empty 2.16 58.5 19.5 No No
3 empty 2.1 62.7 17.2 No No
4 empty 2.44 60.8 17.4 No No
5 empty 1.86 54.8 16.3 No No
6 empty 2.21 68.2 11.6 No No
7 bound 2.12 54.7 11.5 No No
8 bound 2.12 97.3 0 Yes No
9 empty 2.25 65.8 11 No No
10 empty 2.45 67.8 9.8 No No
3P7U_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 66.9 28.3 Yes No
2 empty 2.33 73.2 22 No No
3 empty 2.2 61 20.4 No No
4 empty 2.46 61.9 17.1 No No
5 empty 2.04 63.4 14.4 No No
6 empty 2.04 63.6 22.1 No No
7 empty 2.48 70.8 16 No No
8 empty 2.28 59.7 15.9 No No
9 empty 2.69 70.6 8.3 No No
10 empty 2.28 65.5 10.7 No No
4OI5_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 68.1 29 Yes No
2 empty 2.18 60.3 21.1 No No
3 empty 2.26 66.7 15.7 No No
4 empty 2.44 73.2 15.8 No No
5 empty 2.14 61.4 22.3 No No
6 empty 2.59 60.4 17.9 No No
7 empty 2.26 68.9 12.7 No No
8 bound 2.37 56.5 12.8 No No
9 empty 2.81 70.4 15.4 No No
10 empty 2.45 64.1 12.5 No No
2TMN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 67.8 33.8 Yes No
2 empty 2.29 63.2 17.8 No No
3 empty 2.43 61 17.5 No No
4 empty 2.3 64.1 22.4 No No
5 empty 2.12 66 13.6 No No
6 empty 1.98 64 19.6 No No
7 empty 2.48 76.4 12.7 No No
8 empty 2.45 54.1 10.8 No No
9 empty 2.32 71.7 11.8 No No
10 empty 2.79 73 8.5 No No
5N34_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 69.1 30.4 Yes No
2 empty 2.45 70.7 23.9 No No
3 empty 2.19 58.8 23.6 No No
4 empty 2.41 60.9 18.1 No No
5 empty 2.27 66.9 16.1 No No
6 empty 2.04 62 19.9 No No
7 empty 2.32 70.3 11.1 No No
8 bound 2.34 58.8 12.4 No No
9 empty 2.42 64.9 9.1 No No
10 empty 2.53 71 10.6 No No
5UUA_A Thermolysin No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.83 68.6 22.6 No No
2 empty 2.05 64.1 17.9 No No
3 empty 2.17 66 20.7 No No
4 empty 1.94 60.8 22.3 No No
5 empty 2.32 64.1 14 No No
6 empty 2.43 76.5 15.3 No No
7 bound 2.34 71.7 9.9 No No
8 empty 2.45 64.3 19 No No
9 bound 2.46 53.5 12.9 No No
10 empty 2.29 74.8 11.8 No No
5UUB_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.69 65.6 35.4 Yes No
2 empty 2.4 58.7 21.4 No No
3 empty 2.06 63 17.9 No No
4 empty 2.21 65.8 15.8 No No
5 empty 1.99 61.2 21.9 No No
6 empty 2.35 68.6 19.6 No No
7 empty 2.26 67.2 17.2 No No
8 bound 2.31 68.4 12.9 No No
9 empty 2.59 57.2 11.3 No No
10 bound 2.46 77.6 9 No No
3T8C_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 69.4 29.3 Yes No
2 empty 2.3 71.8 20.2 No No
3 empty 2.28 62.2 18.5 No No
4 empty 2.24 67.6 15.7 No No
5 empty 2.5 63.8 16.4 No No
6 empty 2.1 61.7 22.5 No No
7 empty 2.29 70.5 13 No No
8 bound 2.32 59.4 11.6 No No
9 empty 2.29 74.9 11.9 No No
10 empty 2.51 66.8 9.8 No No
5A3Y_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 70.4 28.2 Yes No
2 empty 2.39 67.2 20.7 No No
3 empty 2.24 59.5 17.8 No No
4 empty 2.13 67.4 15.3 No No
5 empty 1.96 61.2 22.6 No No
6 empty 2.61 61.6 15.8 No No
7 empty 2.35 68.6 13.2 No No
8 empty 2.37 56.1 16 No No
9 empty 2.93 71.5 14 No No
10 bound 2.53 64.7 11.2 No No
1KJO_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.72 70 28.5 Yes No
2 empty 2.15 62 19.2 No No
3 empty 2.37 60.1 20.6 No No
4 empty 2.29 65.7 21.5 No No
5 empty 2 60.8 19.2 No No
6 empty 2.06 62.4 19.1 No No
7 empty 2.29 56.3 18 No No
8 empty 2.45 70.9 14.7 No No
9 empty 2.49 55.5 12.3 No No
10 empty 2.29 76.7 12.5 No No
1HYT_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 72 26.1 Yes No
2 empty 2.18 60.9 18.7 No No
3 empty 2.38 60.8 16.4 No No
4 empty 2.18 64.1 22 No No
5 empty 2 61.9 16.3 No No
6 empty 2.11 67 18.8 No No
7 empty 2.38 68.9 17.3 No No
8 empty 2.87 71.1 10.2 No No
9 empty 2.45 52.6 12.1 No No
10 empty 2.05 59.6 11.7 No No
1KTO_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.81 72.4 27.7 Yes No
2 empty 2.32 67.6 21.4 No No
3 empty 2.16 63.7 18.3 No No
4 empty 2.44 58.8 18.4 No No
5 empty 2.05 68.1 12.7 No No
6 empty 1.97 65.5 19.4 No No
7 empty 2.4 57.6 18.4 No No
8 empty 2.5 68.4 13.7 No No
9 empty 2.3 56.2 16.5 No No
10 empty 2.5 77.3 10 No No
1L3F_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 67.5 32.8 Yes No
2 empty 1.96 64.4 16 No No
3 empty 2.44 61 20.8 No No
4 empty 1.73 63 20.8 No No
5 empty 1.98 58.8 17.4 No No
6 empty 2.33 54.3 18.6 No No
7 empty 2.2 64.4 12.6 No No
8 empty 2.28 78 11.1 No No
9 empty 2.28 82.9 8.2 No No
10 empty 2.34 64 7.8 No No
5FSP_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.46 68.2 30 Yes No
2 bound 1.75 67.8 27.4 No No
3 empty 2.03 66.3 19.5 No No
4 empty 2.42 60.1 17.9 No No
5 empty 2.13 62.4 22.6 No No
6 empty 2.26 70.4 12.9 No No
7 empty 2.47 56.4 13.6 No No
8 empty 2.49 65.6 8.4 No No
9 empty 2.53 77 11.7 No No
10 empty 2.54 70.6 8.4 No No
5TAC_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 66.8 34.9 Yes No
2 empty 2.3 71.5 24 No No
3 empty 2.32 61.2 19.4 No No
4 empty 2.49 59.9 16.4 No No
5 empty 2.05 65.2 17.5 No No
6 empty 2.12 61.7 14 No No
7 empty 2.46 71.6 15.4 No No
8 empty 2.48 55.8 13 No No
9 empty 2.8 63.1 10.6 No No
10 empty 2.72 74.2 8 No No
6QF2_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 67.9 29.9 Yes No
2 bound 2.13 62 16.7 No No
3 bound 2.11 65.9 16.6 No No
4 empty 2.49 65.1 18.2 No No
5 empty 2.22 73.7 15.3 No No
6 empty 2.18 60.9 21.9 No No
7 empty 2.28 71.3 11.8 No No
8 empty 2.15 75.5 11.5 No No
9 bound 2.21 55.7 10.3 No No
10 empty 2.78 63.5 12.1 No No
3QGO_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 64.6 28.6 Yes No
2 empty 2.2 58.1 19.4 No No
3 empty 2.32 58.4 16.4 No No
4 empty 1.84 56.4 21.3 No No
5 empty 1.77 61.3 16.9 No No
6 bound 1.86 98.8 0 Yes No
7 bound 2.36 53.9 10.7 No No
8 empty 2.57 57.9 9.3 No No
9 empty 2.59 68.2 9.6 No No
10 empty 2.46 68 9.9 No No
6D5U_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.84 70.6 24.1 Yes No
2 empty 2.17 61.9 18.1 No No
3 empty 2.4 72.8 20.7 No No
4 empty 2.15 68 18.3 No No
5 bound 1.98 60.1 24.4 No No
6 empty 2.33 63.3 15 No No
7 empty 2.4 66.6 14.5 No No
8 empty 2.22 54 12.2 No No
9 empty 2.29 66.2 12.1 No No
10 empty 2.54 72.2 10.1 No No
5M5F_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 68 27.3 Yes No
2 empty 2.43 72.5 21.9 No No
3 empty 2.3 60.4 23.5 No No
4 empty 2.12 67.1 14.9 No No
5 empty 2.39 60.3 16.9 No No
6 empty 1.95 60.8 21.9 No No
7 empty 2.28 70.9 10.4 No No
8 bound 2.2 61.8 11.3 No No
9 empty 2.49 64.9 14 No No
10 empty 2.6 75.9 9.4 No No
3T8H_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 70 29.6 Yes No
2 empty 2.42 71.3 23.5 No No
3 empty 2.2 61.9 16.9 No No
4 empty 2.25 69.2 20.9 No No
5 empty 2.36 62.6 17.3 No No
6 empty 2.08 61.7 22.5 No No
7 empty 2.14 66.6 15.4 No No
8 bound 2.34 57.8 12.4 No No
9 empty 2.48 64.6 11.7 No No
10 empty 2.62 72.5 9.1 No No
3LS7_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 68 31.3 Yes No
2 empty 2.25 69.8 21.9 No No
3 empty 2.25 61.4 18.7 No No
4 empty 1.97 63.3 23.5 No No
5 empty 2.41 67.2 13.9 No No
6 empty 1.92 63 19.4 No No
7 empty 2.44 70.9 14.6 No No
8 empty 2.4 56.1 11 No No
9 empty 2.53 71.6 9.3 No No
10 empty 2.58 63.2 11.1 No No
5M9W_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 68.5 30.4 Yes No
2 empty 2.32 71 20.5 No No
3 empty 2.25 59.5 18.5 No No
4 empty 2.17 66.9 20.9 No No
5 empty 2.37 60.2 18.4 No No
6 empty 2.01 64.7 20.2 No No
7 empty 2.32 69.2 11.7 No No
8 bound 2.29 54.5 16.3 No No
9 empty 2.26 76.7 11.4 No No
10 empty 2.57 69.1 9.4 No No
2G4Z_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 70.4 27.9 Yes No
2 empty 2.28 63.3 20.5 No No
3 empty 2.48 61.1 18.4 No No
4 empty 1.95 64.1 17.7 No No
5 empty 2.01 60.6 18.9 No No
6 empty 2.53 70.6 16.4 No No
7 empty 2.45 69 12.1 No No
8 empty 2.27 56.1 10.6 No No
9 empty 2.33 74.9 11.3 No No
10 empty 2.1 65.9 9.5 No No
3F28_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.81 69.7 24 Yes No
2 empty 2.38 73.1 22.7 No No
3 empty 2.19 63.1 17.5 No No
4 empty 2.05 65.3 18.6 No No
5 empty 2.1 63.3 18.3 No No
6 empty 2.24 67.5 11.4 No No
7 empty 2.09 73.8 14.6 No No
8 empty 2.21 55 10.8 No No
9 empty 2.58 75.2 9.5 No No
10 empty 2.31 62.7 10.8 No No
1PE7_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 68.8 30.3 Yes No
2 empty 2.14 66.1 29.3 No No
3 empty 2.46 61.7 18.3 No No
4 empty 1.94 63.9 22.2 No No
5 empty 2.08 61.8 19.4 No No
6 empty 2.44 68.6 15.4 No No
7 empty 2.34 57.9 15.5 No No
8 empty 2.48 76.8 10 No No
9 empty 2.5 63.8 8 No No
10 empty 2.24 69.5 7.6 No No
1KKK_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.75 70.1 29.5 Yes No
2 empty 2.22 62.4 18 No No
3 empty 2.44 60.8 18.7 No No
4 empty 2.31 64.7 21.5 No No
5 empty 1.99 63.4 19.2 No No
6 empty 2.05 63.7 18.1 No No
7 empty 2.47 68.9 15.9 No No
8 empty 2.47 59.1 18.6 No No
9 empty 2.42 56.2 12 No No
10 empty 2.57 71.8 8 No No
2WHZ_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 66 34.9 Yes No
2 empty 2.22 67.6 21.9 No No
3 empty 2.19 62.6 18.3 No No
4 empty 2.39 62.8 18.1 No No
5 empty 2.09 63.1 17.5 No No
6 empty 2.03 63.3 20.2 No No
7 empty 2.24 67.6 18 No No
8 empty 2.38 57.8 14.9 No No
9 empty 2.82 67.8 16.2 No No
10 empty 2.65 66.9 8.2 No No
6IG7_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 68.9 28.8 Yes No
2 empty 2.26 61 19.5 No No
3 empty 2.47 62.9 17.3 No No
4 empty 2.07 64.2 21.3 No No
5 empty 2.29 67.5 21.5 No No
6 empty 2.12 61.9 20.6 No No
7 empty 2.38 69.1 11.8 No No
8 empty 2.44 53.6 13.4 No No
9 empty 2.03 57.2 12 No No
10 empty 2.51 74 9.3 No No
1QF0_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 71.5 31.3 Yes No
2 empty 2.21 62.1 19.7 No No
3 empty 2.1 64.4 18.5 No No
4 empty 2.44 60.4 16.6 No No
5 empty 2.03 63.9 18.3 No No
6 empty 2.35 62.9 20.8 No No
7 empty 2.31 57.6 16 No No
8 empty 2.15 67.7 11.5 No No
9 empty 2.56 72.4 7.8 No No
10 empty 2.32 73.6 10.8 No No
5TLN_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 69.7 30.5 Yes No
2 empty 2.52 63.2 32.2 No No
3 empty 2.43 66.9 24.2 No No
4 empty 2.26 64.2 16.5 No No
5 empty 2.04 63.2 20.3 No No
6 empty 2.17 64.7 14.6 No No
7 empty 2.73 73.5 11.5 No No
8 empty 2.56 56.7 10.7 No No
9 empty 2.25 66 9.3 No No
10 empty 2.37 60.4 11.6 No No
4TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 67.6 35.3 Yes No
2 empty 2.33 63.8 32.3 No No
3 empty 2.4 61.7 16.9 No No
4 empty 2.01 65.6 15.7 No No
5 empty 2.03 64.2 18.2 No No
6 empty 2.43 69.4 15.4 No No
7 empty 2.53 61.5 11.3 No No
8 empty 2.59 73.3 7.6 No No
9 empty 2.35 66.1 12.9 No No
10 empty 2.5 68.4 9.5 No No
5DPF_E Thermolysin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 68.3 29.5 Yes Yes
2 empty 2.16 59.4 19.1 No No
3 empty 2.08 64.9 18.1 No No
4 empty 2.07 66 20.8 No No
5 empty 2.36 59.3 16.9 No No
6 empty 1.95 58 20.9 No No
7 empty 2.22 57.1 13.6 No No
8 bound 2.12 56.3 11.7 No No
9 empty 2.47 70.1 9.2 No No
10 empty 2.15 65.1 10.3 No No
1OS0_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 69.2 35.2 Yes No
2 empty 2.19 63.5 16.9 No No
3 empty 2.18 66 22.4 No No
4 empty 2.48 61.6 17.5 No No
5 empty 2.16 62.1 23.9 No No
6 empty 2.16 61.1 19.4 No No
7 empty 2.53 70.9 12.7 No No
8 empty 2.47 61.9 10 No No
9 empty 2.56 72.4 8.6 No No
10 empty 2.42 65.3 10.5 No No
7TLN_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 69 30.7 Yes No
2 empty 2.48 64.8 26.5 No No
3 empty 2.25 63.2 18.9 No No
4 empty 2.26 64.4 22.5 No No
5 empty 2.07 65.1 14 No No
6 empty 1.98 65.1 17.2 No No
7 empty 2.42 51.3 11.3 No No
8 empty 2.76 73.5 9.6 No No
9 empty 2.34 70.4 11 No No
10 empty 2.49 67.6 7.6 No No
3P7S_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 67.1 28.1 Yes No
2 empty 2.35 73 22.3 No No
3 empty 2.2 58.1 19.2 No No
4 empty 2.42 59.3 18.2 No No
5 empty 2.05 65.9 12.9 No No
6 empty 2 64.1 18 No No
7 empty 2.44 67.1 16.4 No No
8 empty 2.4 55.6 11.4 No No
9 empty 2.38 64.4 7.6 No No
10 empty 2.75 76.3 8.9 No No
3MSA_A Thermolysin No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.67 68.2 23.4 No No
2 bound 2.14 58.6 20.1 No No
3 empty 2.14 62.6 18.4 No No
4 bound 2.17 63.6 16.7 No No
5 empty 1.74 54.4 14.7 No No
6 empty 2.23 61.4 12.2 No No
7 empty 2.36 62.8 13.9 No No
8 empty 2.4 53.4 11.3 No No
9 empty 2.59 71.1 8.3 No No
10 empty 2.54 63.5 9.4 No No
3T8D_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 65.4 30.2 Yes No
2 empty 2.15 60 19 No No
3 empty 2.08 63.6 18.4 No No
4 empty 2.07 66 20.7 No No
5 empty 2.33 58.5 15.8 No No
6 empty 1.88 58 17.2 No No
7 bound 2.27 55.4 10.9 No No
8 empty 2.52 69 9 No No
9 empty 2.41 60.6 10.1 No No
10 empty 2.29 66 8.1 No No
5JT9_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 60 25.9 Yes No
2 empty 2.27 65.2 21.4 No No
3 empty 2.18 59.4 19.8 No No
4 empty 2.07 63.5 21.5 No No
5 empty 2.35 60.9 16 No No
6 empty 1.88 55.1 17.2 No No
7 empty 2.45 64.9 12.2 No No
8 bound 2.11 54.5 11.8 No No
9 bound 2.05 97.8 0 Yes No
10 empty 2.59 74.4 8.6 No No
5ONR_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 66.3 32.9 Yes No
2 empty 2.19 62.1 16.3 No No
3 empty 2.05 63.7 18.9 No No
4 empty 2.51 64.3 16.4 No No
5 empty 1.9 59.1 22.9 No No
6 empty 2.33 68 15.2 No No
7 empty 2.39 55.6 13.4 No No
8 empty 2.12 71 11.3 No No
9 empty 2.46 67.1 10 No No
10 empty 2.3 71.7 11.9 No No
5L8P_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 68.1 30.4 Yes No
2 empty 2.23 61.6 18.9 No No
3 empty 2.33 66 15 No No
4 empty 2.32 71 14.3 No No
5 empty 1.95 62 22.3 No No
6 empty 2.39 63 15.6 No No
7 empty 2.42 70.6 11.9 No No
8 empty 2.27 70.2 13.6 No No
9 bound 2.48 54.7 14.6 No No
10 empty 2.81 69.3 15.6 No No
3T73_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 69.7 30.7 Yes No
2 empty 2.47 70.7 21.8 No No
3 empty 2.21 61.2 17 No No
4 bound 2.22 68.4 15.5 No No
5 empty 2.41 62.2 16.4 No No
6 empty 2.04 61.4 23.3 No No
7 empty 2.26 69.8 15.4 No No
8 bound 2.38 55.7 11.7 No No
9 empty 2.52 65.2 14.3 No No
10 empty 2.55 65.9 7.9 No No
5FSJ_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 70.2 29 Yes No
2 empty 2.16 60 19.4 No No
3 empty 1.94 62.9 20.3 No No
4 empty 2.41 60 16.6 No No
5 empty 1.94 62.1 22.7 No No
6 empty 2.3 67.7 15.4 No No
7 empty 2.36 67.5 13.6 No No
8 empty 2.44 54.4 10.6 No No
9 empty 2.49 64.2 7.9 No No
10 empty 2.51 78.7 10.3 No No
5L3U_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 63.2 30.1 Yes No
2 empty 2.17 62.2 18.1 No No
3 empty 2.18 58.5 20 No No
4 empty 2.24 64.5 13.9 No No
5 empty 2.39 60.2 17.3 No No
6 empty 1.76 55.9 15.9 No No
7 empty 2.38 63 11.6 No No
8 bound 2.06 57.9 11.8 No No
9 bound 2.06 98.8 0 Yes No
10 empty 2.43 66.4 10.4 No No
5DPE_E Thermolysin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 66.9 31.1 Yes Yes
2 empty 2.11 59.8 19 No No
3 empty 2.14 64.8 18.1 No No
4 empty 2.08 66.4 14.2 No No
5 empty 2.34 59.1 16.3 No No
6 empty 1.97 58.2 19.8 No No
7 empty 2.26 58 13.5 No No
8 bound 2.1 56.2 11.6 No No
9 empty 2.52 66.3 9.8 No No
10 empty 2.69 73.4 8.5 No No
1ZDP_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 67.7 34.8 Yes No
2 empty 2.07 67.9 23.7 No No
3 empty 2.21 63.5 19.9 No No
4 empty 2.46 60.8 18.4 No No
5 empty 2.19 64.6 15.7 No No
6 empty 2.04 61.7 19.5 No No
7 empty 2.5 75.1 13.7 No No
8 empty 2.49 59.8 14.5 No No
9 empty 2.82 75.1 7.8 No No
10 empty 2.59 65.1 7.9 No No
4N4E_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 70.2 29.2 Yes No
2 empty 2.26 63 20 No No
3 empty 2.37 70.9 15.8 No No
4 empty 1.91 67.2 18.6 No No
5 empty 2.41 62.5 17.3 No No
6 empty 1.95 60.8 21.2 No No
7 empty 2.27 69.9 11.3 No No
8 bound 2.23 55.2 12 No No
9 empty 2.48 66.5 12 No No
10 empty 2.29 71.9 11.6 No No
3DO0_A Thermolysin No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 69.9 22.9 No No
2 empty 2.17 66.9 22.6 No No
3 empty 2.19 60.9 17.3 No No
4 empty 2.38 61.1 17.8 No No
5 empty 1.99 64.6 21.7 No No
6 empty 2.03 62.2 20.7 No No
7 empty 2.24 70.1 17 No No
8 empty 2.35 59.4 15.5 No No
9 empty 2.54 67.1 8.7 No No
10 empty 2.54 67.6 9.9 No No
5JXN_E Thermolysin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 68.2 28.9 Yes Yes
2 empty 2.18 57.4 20.4 No No
3 empty 2.16 63.8 18.6 No No
4 empty 2.06 63 18.4 No No
5 empty 2.3 59.7 15.9 No No
6 empty 1.91 53.3 18.4 No No
7 empty 2.43 65 10.6 No No
8 bound 2.11 53.7 11.7 No No
9 empty 2.49 69.8 8.8 No No
10 empty 2.33 68.9 7.7 No No
5T9K_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 65.1 35.2 Yes No
2 empty 2.24 61.3 19.2 No No
3 empty 2.48 63 17.1 No No
4 empty 2.22 66.3 23.2 No No
5 empty 2.1 65.3 14.2 No No
6 empty 2.12 62.2 16.2 No No
7 empty 2.54 67.8 14.6 No No
8 empty 2.41 58.3 16.7 No No
9 empty 2.95 70 15.2 No No
10 empty 2.91 61.6 11.8 No No
3FB0_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 67.7 30 Yes No
2 empty 2.31 69.6 20.4 No No
3 empty 2.28 60.8 19.3 No No
4 empty 2.18 66.4 15.8 No No
5 empty 1.86 62.6 19.5 No No
6 empty 2.39 65.6 14.5 No No
7 empty 2.42 68.5 12.8 No No
8 empty 2.88 71.6 13.9 No No
9 empty 2.47 54.3 10.2 No No
10 empty 2.38 71.5 11.2 No No
1KR6_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 70 26.6 Yes No
2 empty 2.31 69.9 21.6 No No
3 empty 2.17 62.8 18.5 No No
4 empty 2.48 61.6 18.4 No No
5 empty 2.02 62.2 19.4 No No
6 empty 2.06 64 17.5 No No
7 empty 2.45 70.4 15.7 No No
8 empty 2.36 57.6 18.1 No No
9 empty 2.3 59.4 10.2 No No
10 empty 2.59 74.2 9.1 No No
5T9I_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 67.7 35.7 Yes No
2 empty 2.3 60.7 16.8 No No
3 empty 2.37 69.7 22.7 No No
4 empty 2.47 65.5 17.2 No No
5 empty 2.07 64 22.1 No No
6 empty 2.02 60.6 22.2 No No
7 empty 2.37 73.3 13.6 No No
8 empty 2.93 69.6 15.7 No No
9 empty 2.46 54.8 12.6 No No
10 empty 2.47 65.2 10.4 No No
6TMN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.83 67.5 35.8 Yes No
2 empty 2.26 64.8 16.6 No No
3 empty 2.27 66.2 22.4 No No
4 empty 2.43 59.4 17.7 No No
5 empty 2.07 65.8 14.2 No No
6 empty 1.96 63.5 19.6 No No
7 empty 2.6 72.9 13.6 No No
8 empty 2.51 54 12.2 No No
9 empty 2.66 72.7 8.2 No No
10 empty 2.36 69.4 11.8 No No
1PE5_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 69.2 24.9 Yes No
2 empty 2.06 69.6 23.5 No No
3 empty 2.2 62.3 19.5 No No
4 empty 2.41 58.9 17.7 No No
5 empty 2.3 65.8 19.8 No No
6 empty 2.1 61.7 18.7 No No
7 empty 2.56 76.1 14.6 No No
8 empty 2.39 55.5 11.2 No No
9 empty 2.86 70 12.2 No No
10 empty 2.56 64.5 8.1 No No
3P7W_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 70.5 24.5 Yes No
2 empty 2.35 72.1 23.7 No No
3 empty 2.24 61.4 17.9 No No
4 empty 2.51 57.7 16.9 No No
5 empty 2.03 64.7 17.2 No No
6 empty 2.05 64.2 18.7 No No
7 empty 2.47 67.8 14.7 No No
8 empty 2.43 58.9 10.6 No No
9 empty 2.52 76.4 9.7 No No
10 empty 2.11 66.7 10.3 No No
5T9Q_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.76 65.3 35.2 Yes No
2 empty 2.44 66.2 29.8 No No
3 empty 2.24 61.8 22.2 No No
4 empty 2.54 63.3 18.7 No No
5 empty 2.12 62.6 18.7 No No
6 empty 2.42 70.5 14.7 No No
7 empty 2.5 54.3 12.4 No No
8 empty 2.54 75 9.6 No No
9 empty 2.61 68.2 7.7 No No
10 empty 2.15 61.3 8.7 No No
4D91_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 68 29.1 Yes No
2 empty 2.33 69.7 20.9 No No
3 empty 2.19 62 17.4 No No
4 empty 1.99 63.6 21.4 No No
5 empty 2.45 67.6 14.8 No No
6 empty 2 59.8 19.3 No No
7 empty 2.39 70.6 14.5 No No
8 bound 2.42 55.4 12.3 No No
9 empty 2.3 78.1 11.5 No No
10 empty 2.52 74.2 10.3 No No
3FOR_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 70.9 27.4 Yes No
2 empty 2.2 60.9 19.4 No No
3 empty 2.08 64.5 15.8 No No
4 empty 1.87 63.3 19.4 No No
5 empty 2.36 65.9 21.4 No No
6 empty 2.35 65.7 14.6 No No
7 empty 2.48 63.2 13.6 No No
8 empty 2.22 56.8 10.7 No No
9 empty 2.44 63.3 10.9 No No
10 empty 2.55 73.9 7.8 No No
3FGD_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 68.9 29.3 Yes No
2 empty 2.34 73.1 20.2 No No
3 empty 2.17 61.5 18.2 No No
4 empty 2.45 66.8 15.2 No No
5 empty 2.17 66.5 18.5 No No
6 empty 2.06 64.5 19.2 No No
7 empty 2.36 66 12.6 No No
8 empty 2.43 57.1 12.2 No No
9 empty 2.32 66.7 12.1 No No
10 empty 2.27 73.9 11 No No
5O8N_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 67.3 32.1 Yes No
2 empty 2.18 62.2 18.2 No No
3 empty 2.31 72.1 21.6 No No
4 empty 2 65.4 16.2 No No
5 empty 2.49 60 17.6 No No
6 empty 1.94 60.7 23.1 No No
7 empty 2.31 57.6 16.3 No No
8 empty 2.36 53.3 12.3 No No
9 empty 2.45 74.1 11 No No
10 empty 2.38 74.9 9 No No
3N21_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 68.6 35.2 Yes No
2 empty 2.31 71 24 No No
3 empty 2.14 58.8 21.9 No No
4 empty 2.18 66 17.4 No No
5 empty 2 62.4 20.6 No No
6 empty 2.25 63.5 14.5 No No
7 empty 2.25 66.8 16.1 No No
8 empty 2.47 55.7 12.6 No No
9 empty 2.75 72.9 7.9 No No
10 empty 2.41 63.5 9.8 No No
3FCQ_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.75 68.3 34.7 Yes No
2 empty 2.33 69.9 22.9 No No
3 empty 2.29 61.6 19.5 No No
4 empty 2.46 61.6 18 No No
5 empty 2.17 67.5 14.2 No No
6 empty 2.07 63 17.7 No No
7 empty 2.36 71.7 15.3 No No
8 empty 2.32 55.7 10.7 No No
9 empty 2.48 67.1 11.7 No No
10 empty 2.49 64.6 9.7 No No
5N2T_E Thermolysin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 67.7 31.1 Yes Yes
2 empty 2.11 57.7 18.8 No No
3 empty 2.17 64.5 18.3 No No
4 empty 2.25 63.9 18.4 No No
5 empty 2.36 61.2 16.2 No No
6 empty 1.88 52.6 16.2 No No
7 bound 2.26 52.9 11.1 No No
8 empty 2.41 63.8 10.2 No No
9 empty 2.43 67.3 9.5 No No
10 empty 2.39 67.8 8.2 No No
1KS7_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 71.7 29.5 Yes No
2 empty 2.15 62.3 18.3 No No
3 empty 2.44 60.2 18.2 No No
4 empty 2.29 65.1 21.5 No No
5 empty 1.99 62 19.4 No No
6 empty 2.05 64 18 No No
7 empty 2.36 58.1 17.2 No No
8 empty 2.45 69.5 17.5 No No
9 empty 2.42 56.9 11.6 No No
10 empty 2.99 73.1 9.9 No No
5K7T_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 66.4 34.4 Yes No
2 empty 2.43 65.7 29.1 No No
3 empty 2.42 63.2 18.9 No No
4 empty 2.14 65.2 20.8 No No
5 empty 2.1 61 22.8 No No
6 empty 2.41 71.5 10.7 No No
7 empty 2.41 57.5 15.8 No No
8 empty 2.84 73.9 14.6 No No
9 empty 2.5 62.7 12 No No
10 empty 2.17 56.8 12.2 No No
3NN7_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.39 68 31.2 Yes No
2 bound 1.92 67.9 24.8 No No
3 empty 2.01 67.5 14.1 No No
4 empty 2 61.9 19.4 No No
5 empty 2.27 61.9 12.2 No No
6 empty 2.44 71.4 14 No No
7 empty 2.31 58.6 12.5 No No
8 empty 2.47 67.8 8 No No
9 empty 2.55 76.2 8.6 No No
10 empty 2.27 59.6 12.2 No No
4TLN_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 69 36.3 Yes No
2 empty 2.48 66.7 24.8 No No
3 empty 2.25 63.9 19.9 No No
4 empty 2.56 58.8 18.3 No No
5 empty 2 64.2 18.4 No No
6 empty 2.15 63.9 15 No No
7 empty 2.56 71.5 11.7 No No
8 empty 2.48 53.3 11.1 No No
9 empty 2.08 53.2 12.8 No No
10 empty 2.74 74.3 9.3 No No
5TAI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 67 28.4 Yes No
2 empty 2.37 65.5 28.8 No No
3 empty 2.46 58.3 18.8 No No
4 empty 2.07 65.2 14.8 No No
5 empty 2.12 63.2 18.8 No No
6 empty 2.39 56.4 17.5 No No
7 empty 2.85 71.6 12.2 No No
8 empty 2.2 72.7 10.9 No No
9 empty 2.52 66.4 8 No No
10 empty 2.6 69.1 8.6 No No
2A7G_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 68.3 33.7 Yes No
2 empty 2.41 74.8 22.8 No No
3 empty 2.17 61.6 18.5 No No
4 empty 2.1 66.1 14.1 No No
5 empty 2.52 63.7 16.5 No No
6 empty 2.02 61.4 19.5 No No
7 empty 2.46 68 17.6 No No
8 empty 2.26 58.4 10.8 No No
9 empty 2.79 76.3 8.5 No No
10 empty 2.4 58 12.1 No No
5MA7_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 68.1 30.4 Yes No
2 empty 2.39 70.1 22.5 No No
3 empty 2.16 59.2 19.9 No No
4 empty 2.18 65.4 19.8 No No
5 empty 2.36 60.6 16.9 No No
6 empty 1.97 61.8 22.5 No No
7 empty 2.33 70.6 12 No No
8 bound 2.24 56.9 11.4 No No
9 empty 2.44 63.2 12.8 No No
10 empty 2.46 76.7 9.1 No No
3QH1_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.74 69.8 27.8 Yes No
2 empty 2.23 63 18.7 No No
3 empty 2.34 74.7 23.3 No No
4 empty 2.16 63.2 16.5 No No
5 empty 2.37 61 17.2 No No
6 empty 2.08 61.6 20.2 No No
7 empty 2.28 70.4 14.8 No No
8 empty 2.34 58 11.5 No No
9 empty 2.4 75 10.3 No No
10 empty 2.47 63.9 9 No No
1TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 69.2 29 Yes No
2 empty 2.33 64.3 30.9 No No
3 empty 2.35 62.2 16.1 No No
4 empty 2.01 66.4 15.4 No No
5 empty 1.97 61.9 17.1 No No
6 empty 2.38 70.4 12 No No
7 empty 2.46 65 11.7 No No
8 empty 2.5 73.4 9.4 No No
9 empty 2.56 59.4 10 No No
10 empty 2.24 68.4 8.4 No No
1THL_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 68 29.8 Yes No
2 empty 2.18 61.9 19.2 No No
3 empty 2.28 65.8 22.6 No No
4 empty 2.09 66 16.6 No No
5 empty 2.41 61.1 17.4 No No
6 empty 2.13 61.8 18.5 No No
7 empty 2.32 72.4 11.3 No No
8 empty 2.52 57 13 No No
9 empty 2.11 59 12.2 No No
10 empty 2.46 65.1 10.1 No No
1LNB_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 66.3 35.8 Yes No
2 empty 2.23 65.9 28.7 No No
3 empty 2.41 61.4 19.3 No No
4 empty 1.95 64.4 16.9 No No
5 empty 2.01 61 18.7 No No
6 empty 2.53 69.2 15.8 No No
7 empty 2.39 61 16 No No
8 empty 2.8 70.6 13.4 No No
9 empty 2.46 62.8 9.5 No No
10 empty 2.22 68.5 8 No No
1Y3G_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 70.4 30.1 Yes No
2 empty 2.28 61.9 18 No No
3 empty 2.27 66.9 23.2 No No
4 empty 2.46 60.2 17.9 No No
5 empty 2.05 66.4 15.2 No No
6 empty 1.99 61.2 18.9 No No
7 empty 2.47 66.6 15.5 No No
8 empty 2.42 57.9 11.2 No No
9 empty 2.41 74.9 9.8 No No
10 empty 2.51 63.5 10.1 No No
4MWP_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 62 27.1 Yes No
2 empty 2.14 58.1 19.8 No No
3 empty 2.07 64.7 20.4 No No
4 empty 2.48 60.2 17.4 No No
5 empty 1.88 54.8 15.7 No No
6 empty 2.24 70.5 11.5 No No
7 bound 2.11 55.2 11.8 No No
8 bound 2.03 98.3 0 Yes No
9 empty 2.32 62.3 11 No No
10 empty 2.23 58.1 12.2 No No
3P7V_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.87 66.7 28.2 Yes No
2 empty 2.33 73.2 23.1 No No
3 empty 2.2 61 20.1 No No
4 empty 2.46 59.9 17.6 No No
5 empty 2.08 64.1 19.6 No No
6 empty 1.92 64.7 15 No No
7 empty 2.29 69.3 17.4 No No
8 empty 2.37 59.3 16.9 No No
9 empty 2.41 76.7 10 No No
10 empty 2.39 68.4 9.1 No No
3FBO_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.29 66.2 29.5 Yes No
2 empty 1.98 68.3 29.7 No No
3 empty 2.16 64.3 21 No No
4 empty 2.38 61.4 16.9 No No
5 empty 2.09 64.1 16.9 No No
6 empty 2.28 68.7 12.7 No No
7 empty 2.34 57.5 15.1 No No
8 empty 2.6 73.4 8.3 No No
9 empty 2.37 62 13 No No
10 empty 2.19 64.3 9.5 No No
5N31_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 68.9 30.8 Yes No
2 empty 2.21 59.8 23.9 No No
3 empty 2.3 69.6 20.8 No No
4 empty 2.5 62.5 16.5 No No
5 empty 2.06 65.3 15.8 No No
6 empty 1.95 62.8 18.7 No No
7 empty 2.43 68.8 16.4 No No
8 bound 2.19 56.3 10.7 No No
9 empty 2.47 65.9 8 No No
10 empty 2.3 72.2 11.6 No No
5UU7_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 69.6 30.9 Yes No
2 empty 2.17 61.8 18.8 No No
3 empty 2.51 57.3 21.5 No No
4 empty 2.17 66.8 21.7 No No
5 empty 2.16 67.7 13.9 No No
6 empty 1.94 61.3 22.5 No No
7 empty 2.08 72.3 12.1 No No
8 empty 2.88 67.6 14.3 No No
9 empty 2.38 52.6 12.4 No No
10 empty 2.42 61.5 8.6 No No
3P7Q_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 66.2 34.9 Yes No
2 empty 2.33 73.9 22.8 No No
3 empty 2.21 59.3 17.2 No No
4 empty 2.42 60.1 18.2 No No
5 empty 2.05 63.3 16.1 No No
6 empty 2 63.5 19.3 No No
7 empty 2.34 67.1 14.2 No No
8 empty 2.37 54.8 11.9 No No
9 empty 2.55 75.8 8.6 No No
10 empty 2.38 65.8 6.7 No No
1QF1_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 71.7 30.3 Yes No
2 empty 2.12 61.5 19 No No
3 empty 2.27 66.6 23.7 No No
4 empty 2.41 58.8 17.1 No No
5 empty 2.07 65.9 18.5 No No
6 empty 1.97 65 18.3 No No
7 empty 2.24 69.1 11.5 No No
8 empty 2.27 55.7 10.4 No No
9 empty 2.4 66.4 6.9 No No
10 empty 2.63 73.8 7.7 No No
3MSN_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 69.6 33.9 Yes No
2 empty 2.21 62.3 18.2 No No
3 empty 2.32 67.8 21.1 No No
4 bound 2.14 64.7 17.4 No No
5 empty 2.32 62.9 14.6 No No
6 empty 1.96 64.5 19 No No
7 empty 2.4 69.2 15.3 No No
8 empty 2.28 58.3 16.6 No No
9 empty 2.72 63.5 11.2 No No
10 empty 2.2 74.5 11.9 No No
1FJ3_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 69.1 29.4 Yes No
2 empty 2.21 62.8 17.6 No No
3 empty 2.17 66.4 24.4 No No
4 empty 2.41 61.2 17 No No
5 empty 1.87 61.9 19.1 No No
6 empty 2.02 68.6 13.5 No No
7 empty 2.49 68.8 14.7 No No
8 empty 2.79 72.3 15.7 No No
9 empty 2.52 58.6 10.5 No No
10 empty 2.49 64 11.7 No No
1GXW_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 66.9 29.8 Yes No
2 empty 2.38 68.1 22.4 No No
3 empty 2.23 61.6 17 No No
4 empty 2.2 60.3 25.8 No No
5 empty 2.4 60.6 17.8 No No
6 empty 2.03 64.3 18 No No
7 empty 2.36 71.7 13.7 No No
8 empty 2.47 55.9 9.9 No No
9 empty 2.44 67.4 8.4 No No
10 empty 2.55 73.9 8.6 No No
2WI0_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 66.9 34.7 Yes No
2 empty 2.32 70 22.6 No No
3 empty 2.28 61.2 18.3 No No
4 empty 2.45 59.9 18 No No
5 empty 2.13 65.5 17.1 No No
6 empty 2.03 62.9 18.1 No No
7 empty 2.34 68.2 14.2 No No
8 empty 2.41 58.2 13.9 No No
9 empty 2.38 68.9 9.4 No No
10 empty 2.5 73.2 9.7 No No
1TLP_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 68.8 32.6 Yes No
2 empty 2.27 63.4 19.5 No No
3 empty 2.42 60.6 17 No No
4 empty 2.27 64.3 22.4 No No
5 empty 2.09 65.8 16.4 No No
6 empty 1.98 64.8 18.3 No No
7 empty 2.47 74.1 11.6 No No
8 empty 2.42 52.4 10.6 No No
9 empty 2.64 74.1 8.5 No No
10 empty 2.35 70.5 11 No No
1FJU_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 68.9 30.1 Yes No
2 empty 2.19 64.9 29.9 No No
3 empty 2.42 63.2 15.2 No No
4 empty 2.05 64.6 21.9 No No
5 empty 1.91 62.4 15.4 No No
6 empty 2.41 71.4 15.4 No No
7 empty 2.91 69.3 14.6 No No
8 empty 2.5 58.6 9.8 No No
9 empty 2.42 65.4 9.4 No No
10 empty 2.41 68.2 7.8 No No
4D9W_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 69.2 28.4 Yes No
2 empty 2.37 72.6 20.9 No No
3 empty 2.23 62.4 17.4 No No
4 empty 1.96 64.5 21.9 No No
5 empty 2.47 64.4 16.3 No No
6 empty 1.97 59.7 21.8 No No
7 empty 2.29 70.5 13.2 No No
8 bound 2.37 53.9 11.2 No No
9 empty 2.31 76.4 11.3 No No
10 empty 2.63 70.3 10.7 No No
1QF2_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 69.7 24.2 Yes No
2 empty 2.22 60.5 17 No No
3 empty 2.39 62.6 18 No No
4 empty 2.23 66.3 23.1 No No
5 empty 2.08 64.1 19 No No
6 empty 2.04 61.5 19.1 No No
7 empty 2.37 69.3 14.5 No No
8 empty 2.43 59.7 10.7 No No
9 empty 2.56 71.2 8.5 No No
10 empty 2.44 65.1 10.5 No No
6D5P_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 69.5 30.3 Yes No
2 empty 2.16 63.5 19.2 No No
3 empty 2.57 59.8 15.7 No No
4 bound 2.12 65.5 19.1 No No
5 empty 2.16 71.3 12.4 No No
6 empty 2.07 60.5 22.4 No No
7 empty 2.31 67 12.9 No No
8 empty 2.35 58.9 16.7 No No
9 empty 2.14 75.8 11.3 No No
10 empty 2.52 72.8 8.8 No No
5UUC_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.73 66.5 28.7 Yes No
2 empty 2.4 57.2 20.2 No No
3 empty 2.06 60.4 18.5 No No
4 empty 2.3 66.2 21.7 No No
5 empty 2.16 65.4 19.8 No No
6 empty 1.95 60.2 20.8 No No
7 empty 2.31 71 11.5 No No
8 bound 2.42 60.3 11.9 No No
9 empty 2.52 73.5 8.1 No No
10 bound 2.25 68.9 8.5 No No
3SSB_B Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 67.5 29 Yes No
2 empty 2.08 63 18.6 No No
3 empty 2.41 76.7 23.5 No No
4 empty 2.54 61.9 18.7 No No
5 empty 2.12 64.3 17.6 No No
6 empty 2.17 60.4 21.1 No No
7 empty 2.31 71.5 10.6 No No
8 empty 2.44 60.7 12.4 No No
9 empty 2.62 70.7 10.4 No No
10 empty 2.55 73.7 9.4 No No
5TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 68.1 35.3 Yes No
2 empty 2.2 64.8 33 No No
3 empty 2.44 63 17.9 No No
4 empty 2.07 62.5 22.2 No No
5 empty 1.99 64.9 13.1 No No
6 empty 2.44 73.7 12.4 No No
7 empty 2.8 66.2 10.7 No No
8 empty 2.61 60.1 10.8 No No
9 empty 2.42 67.1 12.8 No No
10 empty 2.22 59.7 11.7 No No
3P7R_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.84 65.9 34.3 Yes No
2 empty 2.37 72.5 22.5 No No
3 empty 2.22 58.9 19.3 No No
4 empty 2.42 60.4 18.2 No No
5 empty 2.06 64.4 16.1 No No
6 empty 2 63.5 19.3 No No
7 empty 2.36 67 16.6 No No
8 empty 2.42 57.2 11.4 No No
9 empty 2.62 74 9 No No
10 empty 2.36 67.4 7.9 No No
3MSF_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 67.9 34.8 Yes No
2 empty 2.29 60.8 24.5 No No
3 empty 2.28 71.8 20.4 No No
4 empty 2.15 66.7 17.4 No No
5 empty 2.38 60.5 16.3 No No
6 empty 2.11 61.4 19.6 No No
7 empty 2.35 59.4 11.5 No No
8 empty 2.45 69.7 11.3 No No
9 empty 2.72 63.9 15.2 No No
10 empty 2.34 78 12.1 No No
1LNE_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 68.1 29.9 Yes No
2 empty 2.53 64.2 30.9 No No
3 empty 2.24 63.6 19.2 No No
4 empty 2.24 66.4 22.6 No No
5 empty 2.07 66.9 15.4 No No
6 empty 2.11 63.2 18.1 No No
7 empty 2.33 58.2 17.5 No No
8 empty 2.55 64.7 7.4 No No
9 empty 2.54 72.5 8.1 No No
10 empty 2.36 65.2 9 No No
5LIF_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 67 29.5 Yes No
2 empty 2.32 73.9 22 No No
3 empty 2.17 59.7 17.5 No No
4 empty 2.11 64.5 20.6 No No
5 empty 2.49 64.7 15 No No
6 empty 1.93 62.6 21.3 No No
7 empty 2.28 71.1 10.9 No No
8 bound 2.26 58.4 9.8 No No
9 empty 2.59 70.8 9.3 No No
10 empty 2.61 72.8 8.2 No No
4MTW_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.98 60.2 27.8 Yes No
2 empty 2.21 58 19.8 No No
3 empty 1.9 63.9 15.6 No No
4 empty 2.38 60.8 16.2 No No
5 empty 1.86 55.5 16.3 No No
6 empty 2.23 69.4 11.6 No No
7 bound 2.1 55.1 11.8 No No
8 bound 2.03 98.9 0 Yes No
9 empty 2.28 66.5 9.4 No No
10 empty 2.45 67.4 9.8 No No
1LNC_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 68.5 35.4 Yes No
2 empty 2.22 62.8 19.2 No No
3 empty 2.4 60.9 17.5 No No
4 empty 2.22 64.6 16.5 No No
5 empty 2.02 64.1 17.1 No No
6 empty 2.25 69.5 18.8 No No
7 empty 2.44 69.9 15.9 No No
8 empty 2.8 70.9 13.3 No No
9 empty 2.58 56.2 12.3 No No
10 empty 2.48 66 10.2 No No
5LWD_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 63.4 29 Yes No
2 empty 2.15 57.5 20.6 No No
3 empty 2.09 63.1 17.6 No No
4 empty 2.09 65.4 14.9 No No
5 empty 2.31 59.1 15.9 No No
6 empty 1.89 57 16.5 No No
7 empty 2.35 64.1 10.6 No No
8 bound 2.11 52.9 11.2 No No
9 bound 2.1 99.4 0 Yes No
10 empty 2.51 70 8.9 No No
1FJT_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 69.6 24.7 Yes No
2 empty 2.21 61.4 19.5 No No
3 empty 2.41 63.8 17.7 No No
4 empty 2.25 66.3 22.9 No No
5 empty 2.03 65.5 21.6 No No
6 empty 1.95 62.3 19.6 No No
7 empty 2.39 72.5 14.8 No No
8 empty 2.45 66.3 7.9 No No
9 empty 2.54 56.9 9.9 No No
10 empty 2.44 72.7 8.9 No No
1TRL_B Thermolysin No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.05 58.9 17.6 No No
2 empty 1.85 56.4 10.6 No No
3 empty 2.2 54.8 10.5 No No
4 empty 2.01 62.6 6.6 No No
5 empty .69 71.7 6.6 No No
6 empty 2.23 61.4 6.2 No No
7 empty 2.63 65.5 5 No No
8 empty 2.7 63 0 No No
9 empty 2.98 63.6 5.9 No No
10 empty 2.56 62 5.9 No No
1LNA_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 70 31.1 Yes No
2 empty 2.22 62.6 19.9 No No
3 empty 2.45 60.5 19.3 No No
4 empty 2.17 66.8 21.8 No No
5 empty 2.1 63.8 19.4 No No
6 empty 2.06 68.8 18.8 No No
7 empty 2.51 72.6 13.8 No No
8 empty 2.45 60.9 12.1 No No
9 empty 2.05 54.5 12 No No
10 empty 2.03 57.5 9.8 No No
1FJQ_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 68.2 34.3 Yes No
2 empty 2.17 61.9 19.1 No No
3 empty 2.16 66.3 23.6 No No
4 empty 2.44 61.9 16.6 No No
5 bound 2.03 61.9 18.6 No No
6 bound 2.03 65.4 19.4 No No
7 empty 2.47 70 15.9 No No
8 empty 2.44 60.8 11.4 No No
9 empty 2.54 73.9 8 No No
10 empty 2.46 64 8.2 No No
3P7P_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.84 67 35.7 Yes No
2 empty 2.36 74.1 21.7 No No
3 empty 2.19 59.6 18.4 No No
4 empty 2.41 60.4 18.3 No No
5 empty 2.04 64.6 16.6 No No
6 empty 1.99 61.9 22.8 No No
7 empty 2.49 70.3 13.2 No No
8 empty 2.4 56.9 11.9 No No
9 empty 2.65 74.3 8.6 No No
10 empty 2.45 66.5 6.9 No No
3EIM_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 66.4 34.4 Yes No
2 empty 2.34 72 24 No No
3 empty 2.19 61 18.2 No No
4 empty 2.12 64.3 19.9 No No
5 empty 2.38 66.8 13.6 No No
6 empty 1.98 63 19.4 No No
7 empty 2.4 70.6 14.5 No No
8 empty 2.3 55.7 15.1 No No
9 empty 2.59 71.1 8.6 No No
10 empty 2.42 63.7 7.9 No No
6D5Q_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 66.5 36.1 Yes No
2 empty 2.26 60.3 17.4 No No
3 bound 2.16 64.2 21.8 No No
4 empty 2.47 64.8 15 No No
5 bound 2 62.2 23 No No
6 empty 2.54 66.5 13.2 No No
7 empty 2.19 72.1 11.4 No No
8 empty 2.81 66.7 13.1 No No
9 empty 2.28 54.5 15.9 No No
10 empty 2.21 73.6 11 No No
1KRO_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 69.1 30.6 Yes No
2 empty 2.29 69.2 21.4 No No
3 empty 2.23 63.1 17.4 No No
4 empty 2.45 59.5 20.5 No No
5 empty 2.06 62.4 14 No No
6 empty 2.03 60.9 19.4 No No
7 empty 2.48 70.8 15 No No
8 empty 2.23 55.5 18.4 No No
9 empty 2.42 56.8 11.5 No No
10 empty 2.36 67 11.4 No No
1PE8_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.73 68.9 30.3 Yes No
2 empty 2.19 66.1 30.8 No No
3 empty 2.45 61.9 19.3 No No
4 empty 2.09 60.4 19.1 No No
5 empty 1.91 65.5 19.1 No No
6 empty 2.39 69.7 14.7 No No
7 empty 2.39 59.8 15.4 No No
8 empty 2.44 72.4 8.5 No No
9 empty 2.52 61.1 11 No No
10 empty 2.22 63.8 8.8 No No
3T8F_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 68.1 29.8 Yes No
2 empty 2.16 60.3 19.7 No No
3 empty 2.46 70.2 16 No No
4 bound 2.13 67 14.8 No No
5 empty 2.5 64.4 15.6 No No
6 empty 1.99 60.5 22.5 No No
7 empty 2.33 69.2 12.9 No No
8 bound 2.35 59.4 11.9 No No
9 empty 2.5 67.9 10.1 No No
10 empty 2.26 71.5 10.6 No No
1FJO_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 67.8 35.3 Yes No
2 empty 2.1 64.7 30.4 No No
3 empty 2.39 63 17.9 No No
4 bound 1.97 65.2 17.6 No No
5 empty 2.06 67.8 13.5 No No
6 empty 2.41 72.5 15.4 No No
7 empty 2.55 71.4 7.6 No No
8 empty 2.55 57.8 10.4 No No
9 empty 2.47 65.8 7.6 No No
10 empty 2.31 59.3 12.5 No No
4N5P_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 62.4 28.4 Yes No
2 empty 2.13 59.3 19 No No
3 empty 2.07 66.1 19.3 No No
4 empty 2.41 61 17.2 No No
5 empty 1.88 56.3 16.4 No No
6 empty 2.25 72.4 11.5 No No
7 bound 2.09 55.1 11.9 No No
8 bound 2.04 100 0 Yes No
9 empty 2.26 56.5 10 No No
10 empty 2.48 68 8.5 No No
5UU8_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 67.2 25.2 Yes No
2 empty 2.41 61.1 20.3 No No
3 empty 1.94 63.9 14.2 No No
4 empty 1.99 60.5 22.1 No No
5 empty 1.96 64.3 15.5 No No
6 empty 2.33 74 18 No No
7 empty 2.28 68.7 12.2 No No
8 empty 2.16 63.3 18.1 No No
9 empty 2.44 55.3 18.2 No No
10 bound 2.7 70.3 9.2 No No
6QF3_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 68.4 24.6 Yes No
2 bound 2.02 60.2 20.5 No No
3 bound 2.05 64.7 20.4 No No
4 bound 2.41 59.7 17.7 No No
5 bound 1.89 57.2 22 No No
6 empty 1.93 65.6 12.9 No No
7 bound 2.09 56.3 10.5 No No
8 empty 1.83 59.2 11.2 No No
9 empty 2.61 69.2 8.8 No No
10 empty 2.1 66.5 8.8 No No
5JS3_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 69.6 29.4 Yes No
2 empty 2.37 73 21.2 No No
3 empty 2.29 62.4 18.7 No No
4 empty 1.94 66.7 16.5 No No
5 empty 2.46 63.4 16 No No
6 empty 1.95 60.1 21.2 No No
7 empty 2.42 70.2 11.2 No No
8 bound 2.22 60.7 12 No No
9 empty 2.47 65.7 8.9 No No
10 empty 2.59 73.2 8.2 No No
3SSB_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 69.3 26.6 Yes No
2 empty 2.55 63.5 20.7 No No
3 empty 2.08 63.6 17.9 No No
4 empty 1.88 65.5 14.4 No No
5 empty 2.04 62 18.3 No No
6 empty 2.31 71.3 16.2 No No
7 empty 2.43 56.4 13 No No
8 empty 2.12 66.3 12.8 No No
9 empty 2.26 73.1 11.6 No No
10 empty 2.42 67.6 12 No No
3T2J_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 66.7 29.6 Yes No
2 empty 2.03 66 17.8 No No
3 empty 1.9 63.8 16.1 No No
4 empty 2.1 61.6 19.6 No No
5 empty 2.56 64.6 17 No No
6 empty 2.22 69.8 14.6 No No
7 empty 2.17 72.3 11 No No
8 empty 2.51 54.6 12 No No
9 bound 2.22 76.6 12.1 No No
10 empty 2.68 70 8.4 No No
5TMN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.81 67.2 35.7 Yes No
2 empty 2.26 64.5 17.7 No No
3 empty 2.27 64.6 22.3 No No
4 empty 2.45 61.2 17.1 No No
5 empty 2.12 65.7 13.7 No No
6 empty 1.95 64.5 19.6 No No
7 empty 2.49 76.6 12.2 No No
8 empty 2.39 57.4 11.5 No No
9 empty 2.67 75.1 8 No No
10 empty 2.39 71 12.3 No No
6D5O_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 68.6 35.4 Yes No
2 empty 2.24 63.7 16.8 No No
3 empty 2.14 67.5 22.3 No No
4 empty 2.44 62.1 17.8 No No
5 bound 2 60.2 24.1 No No
6 bound 2.24 68.3 18.5 No No
7 empty 2.29 56.3 15.9 No No
8 empty 2.82 68.6 15.2 No No
9 empty 2 76 9.3 No No
10 empty 2.38 66.2 14 No No
3FXP_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 67.4 33.9 Yes No
2 empty 2.25 71.7 21.9 No No
3 empty 2.17 63 19.1 No No
4 empty 2.1 69.2 14 No No
5 empty 2.39 60 18.5 No No
6 empty 2.06 61.6 25.8 No No
7 empty 2.45 72.6 12 No No
8 empty 2.19 60.5 10 No No
9 empty 2.57 73.1 8.9 No No
10 empty 2.56 63.5 6.3 No No
5N2Z_E Thermolysin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 67.3 31.1 Yes Yes
2 empty 2.19 61.1 19.1 No No
3 empty 2.15 63.7 18.7 No No
4 empty 2.26 64.2 17.6 No No
5 empty 2.36 59 16.2 No No
6 empty 1.79 54.2 16.1 No No
7 bound 2.25 52.4 11.7 No No
8 empty 2.38 60.5 10.6 No No
9 empty 2.18 65.9 9.1 No No
10 empty 2.29 67.4 8.1 No No
3DO1_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 70.1 30.7 Yes No
2 empty 2.11 65.8 30.8 No No
3 empty 2.49 64.3 31.5 No No
4 empty 2.01 63.4 19 No No
5 empty 2.04 64.4 16.9 No No
6 empty 2.41 59.9 15.1 No No
7 empty 2.62 74.6 7.9 No No
8 empty 2.43 66.5 6.6 No No
9 empty 2.63 71.1 10.4 No No
10 empty 2.07 53.3 8.7 No No
4TNL_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 69.7 30.7 Yes No
2 empty 2.33 71.1 21.1 No No
3 empty 2.18 61.9 16.6 No No
4 empty 2.45 58.9 18.1 No No
5 empty 1.98 66.1 18.4 No No
6 empty 2.12 61.9 21.3 No No
7 empty 2.41 72.8 10.6 No No
8 empty 2.83 67.5 14.1 No No
9 empty 2.44 54.4 11.7 No No
10 empty 2.56 67.3 9.8 No No
1TLX_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 69.4 29.4 Yes No
2 empty 2.19 64.9 30.4 No No
3 empty 2.39 61.8 17.9 No No
4 empty 2.02 66.3 15.5 No No
5 empty 1.95 62.9 17.1 No No
6 empty 2.44 72.4 15.4 No No
7 empty 2.34 66.3 13.4 No No
8 empty 2.36 59.2 9.6 No No
9 empty 2.56 72.2 9.4 No No
10 empty 2.75 64.2 7.8 No No
5UUE_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 65.6 30.3 Yes No
2 empty 2.04 62.1 17.7 No No
3 empty 2.46 63.3 20.9 No No
4 bound 1.94 67.2 13.6 No No
5 empty 2.03 60.6 23.1 No No
6 empty 2.54 67.7 20.1 No No
7 empty 2.16 69.2 13.6 No No
8 empty 2.3 54.6 10.7 No No
9 bound 2.39 67.3 11.6 No No
10 empty 2.59 72.7 8.5 No No
8TLN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 70.5 28.6 Yes No
2 empty 2.16 61.5 16.5 No No
3 empty 2.42 61 17.4 No No
4 empty 2.24 66.3 21.9 No No
5 empty 2.02 62.4 18.6 No No
6 empty 2.11 66.6 13.5 No No
7 empty 2.41 68.9 13.6 No No
8 empty 2.81 69 13 No No
9 empty 2.53 55.5 11.9 No No
10 empty 2.01 53.5 9.9 No No
3T2H_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 67.4 29.8 Yes No
2 empty 1.96 63 14.6 No No
3 empty 2.5 62.1 19.6 No No
4 empty 1.84 64.4 18.7 No No
5 empty 2.07 61 22.8 No No
6 empty 2.29 73.9 8.5 No No
7 empty 2.39 66.8 10.3 No No
8 empty 2.64 71.8 8.4 No No
9 empty 2.26 74.4 11.4 No No
10 empty 2.52 51.8 12.9 No No
1TRL_A Thermolysin No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.7 56.3 21.3 No No
2 empty 1.84 58.6 9.2 No No
3 empty 2.2 62 8.4 No No
4 empty 2.24 57.9 11.5 No No
5 empty 2.01 49 7.5 No No
6 empty 2.41 73.2 7 No No
7 empty 2.39 71.6 5.2 No No
4TMN_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 68.4 35.5 Yes No
2 empty 2.5 66.5 25.7 No No
3 empty 2.29 61.8 17.1 No No
4 empty 2.31 64.2 22.4 No No
5 empty 2.05 64.5 20.2 No No
6 empty 2.1 64.3 19.9 No No
7 empty 2.39 53.4 12.9 No No
8 empty 2.31 73.1 12.2 No No
9 empty 2.62 68.8 8.5 No No
10 empty 2.51 69.9 7.5 No No
5FSS_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 70.2 27.5 Yes No
2 empty 2.32 70.8 23.9 No No
3 empty 2.16 61.4 17.7 No No
4 empty 2.12 66.7 22 No No
5 empty 2.48 66.8 14 No No
6 empty 2.18 62.4 21.3 No No
7 empty 2.34 66.8 12.5 No No
8 empty 2.4 55 14 No No
9 empty 2.62 76.9 11.9 No No
10 empty 2.44 65.5 10.1 No No
5JVI_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 61.3 29.3 Yes No
2 empty 2.15 58.8 19.2 No No
3 empty 2.28 63.9 21.4 No No
4 empty 1.94 63.6 16.3 No No
5 empty 2.37 59.9 16.5 No No
6 empty 1.91 53.4 15.8 No No
7 empty 2.35 65.4 11.9 No No
8 bound 2.14 56.8 11.8 No No
9 bound 2.06 98.9 0 Yes No
10 empty 2.48 67 9.8 No No
1FJV_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 69.3 29.4 Yes No
2 empty 2.25 64.9 30.4 No No
3 empty 2.41 63.2 16.7 No No
4 empty 2.04 64.5 15.9 No No
5 empty 1.98 63.2 19.2 No No
6 empty 2.39 68.1 14.9 No No
7 empty 2.53 63.9 11.1 No No
8 empty 2.55 59.5 9.7 No No
9 empty 2.56 69.7 8 No No
10 empty 2.32 62.9 9.1 No No
7TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.84 66.9 31.8 Yes No
2 empty 2.16 59.6 19.8 No No
3 empty 2.31 62.4 17.6 No No
4 empty 1.99 65.1 17.5 No No
5 empty 1.89 55.2 16.8 No No
6 empty 1.88 56.3 14.1 No No
7 empty 2.12 77.8 9.2 No No
8 empty 2.45 47.9 12.4 No No
9 empty 2.52 71.4 8.9 No No
10 empty 2.24 63.2 9.3 No No
3FLF_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.98 66.5 33.7 Yes No
2 empty 2.42 69.5 22.4 No No
3 empty 2.16 63 19.6 No No
4 empty 1.9 65.9 22.9 No No
5 empty 1.92 60.7 18.1 No No
6 empty 2.36 65.8 12 No No
7 empty 2.42 71.6 15.3 No No
8 empty 2.33 59.5 10.7 No No
9 empty 2.44 65.2 9.1 No No
10 empty 2.57 69.8 9.7 No No
2TLX_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 70.2 29.8 Yes No
2 empty 2.27 62 19 No No
3 empty 2.47 65 16.4 No No
4 empty 2.03 63.5 15.9 No No
5 empty 2.2 65 15.8 No No
6 empty 2.35 62 19.9 No No
7 empty 2.41 68.3 13.6 No No
8 empty 2.5 55.2 12.5 No No
9 empty 2.5 73.2 9.4 No No
10 empty 2.25 75.3 12.4 No No
3FV4_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 68.5 27.3 Yes No
2 empty 2.3 64.5 18.6 No No
3 empty 2.23 71.1 21 No No
4 empty 2.02 64.8 16.2 No No
5 empty 2.38 66.9 15.3 No No
6 empty 1.95 63.1 19.3 No No
7 empty 2.4 72.4 14.6 No No
8 empty 2.24 56.1 10.5 No No
9 empty 2.45 66.6 8.4 No No
10 empty 2.32 74 11.4 No No
3T8G_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 68.9 26.8 Yes No
2 empty 2.34 71.4 20.2 No No
3 empty 2.23 59.7 18.5 No No
4 bound 2.27 65.8 21.7 No No
5 empty 2.38 62.5 16.4 No No
6 empty 2.02 59.1 23 No No
7 empty 2.25 71.4 14.2 No No
8 bound 2.22 57.5 10.8 No No
9 empty 2.47 67.4 9.8 No No
10 empty 2.28 73.5 11.9 No No
3F2P_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 67.8 28.1 Yes No
2 empty 2.4 66.5 24.3 No No
3 empty 1.93 64.7 18.8 No No
4 empty 2.37 65.9 15.5 No No
5 empty 1.78 59 14.6 No No
6 empty 2.37 70.5 13.7 No No
7 empty 2.2 54.4 10.5 No No
8 empty 2.31 71.6 11.4 No No
9 empty 2.53 67.1 10.2 No No
10 empty 2.58 77.8 10.1 No No
1KJP_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.68 71 27.9 Yes No
2 empty 2.31 68.1 21.9 No No
3 empty 2.14 62.4 18.4 No No
4 empty 2.5 59.8 17.9 No No
5 empty 1.99 61.7 21.4 No No
6 empty 2.07 62.9 19.1 No No
7 empty 2.45 69.2 17.5 No No
8 empty 2.25 57.5 18.4 No No
9 empty 2.43 55.9 12 No No
10 empty 2.78 64.2 10.8 No No
5UUD_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.73 65.9 24.9 Yes No
2 empty 2.42 60.6 22.2 No No
3 empty 2.03 62.6 19.4 No No
4 empty 1.99 60 22.5 No No
5 empty 1.82 64.5 21 No No
6 bound 2.35 69.6 16.8 No No
7 empty 2.11 74 9.7 No No
8 empty 2.66 71.7 8.6 No No
9 empty 2.22 58.3 11.7 No No
10 empty 2.2 61.2 10.2 No No
4N66_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 67.7 29.5 Yes No
2 empty 2.36 70.9 20.7 No No
3 empty 2.24 60.6 17.8 No No
4 empty 2.08 66.5 21.1 No No
5 empty 2.11 60.8 21.9 No No
6 empty 2.42 62.6 15.6 No No
7 bound 2.28 55.2 17.3 No No
8 empty 2.39 70.1 12.4 No No
9 empty 2.3 72.4 11.8 No No
10 empty 2.6 75.5 8.2 No No
3P7T_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.83 66.4 28.5 Yes No
2 empty 2.33 72.9 22.5 No No
3 empty 2.18 60.5 21.2 No No
4 empty 2.47 60.4 18.2 No No
5 empty 2.04 64.2 12.9 No No
6 empty 1.96 62.7 15.3 No No
7 empty 2.36 68.6 14.1 No No
8 empty 2.36 55.8 9.8 No No
9 empty 2.92 72 13.1 No No
10 empty 2.41 62.7 11.3 No No
5LVD_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 67 34.6 Yes No
2 empty 2.45 73.1 20.6 No No
3 empty 2.18 59.7 18.5 No No
4 empty 2.14 66.2 21.1 No No
5 empty 2.37 60.9 16.9 No No
6 empty 1.95 59.9 21.6 No No
7 empty 2.3 69.1 10.8 No No
8 empty 2.39 53 11.3 No No
9 empty 2.44 64.8 12.1 No No
10 empty 2.58 68.6 8.4 No No
6D5R_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.85 68.8 29.8 Yes No
2 empty 2.22 62.7 16.4 No No
3 bound 2.01 64.8 16.7 No No
4 empty 1.93 62.6 23.1 No No
5 empty 2.44 61.1 15.5 No No
6 empty 2.2 72.1 14.1 No No
7 empty 2.35 67.6 12.7 No No
8 empty 2.3 55.2 16.2 No No
9 empty 2.76 65.9 15.7 No No
10 empty 2.43 63.9 15 No No
3TLI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 70.3 28.9 Yes No
2 empty 2.13 64.3 31.7 No No
3 empty 2.38 61.5 17 No No
4 empty 2.05 66.2 15.8 No No
5 empty 1.98 61.4 18.6 No No
6 empty 2.43 70.7 15 No No
7 empty 2.87 70.7 13.4 No No
8 empty 2.53 57 10.3 No No
9 empty 2.43 62.5 11.1 No No
10 empty 2.26 62.7 12.5 No No
1KEI_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 68.8 29 Yes No
2 empty 2.14 64.1 17.7 No No
3 empty 2.44 60.9 19.3 No No
4 empty 2.21 66.1 23.4 No No
5 empty 2.14 62.3 17.1 No No
6 empty 2.03 64.3 19.2 No No
7 empty 2.47 69.9 15 No No
8 empty 2.33 58 10.7 No No
9 empty 2.5 72.5 9.5 No No
10 empty 2.62 69.7 7.3 No No
3FVP_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 66.4 29.9 Yes No
2 empty 2.24 70.4 20.6 No No
3 empty 2.18 61.4 16.3 No No
4 empty 2.48 60.9 17.3 No No
5 empty 2.14 64.9 23.1 No No
6 empty 2.15 62.1 18.2 No No
7 empty 2.47 74.1 9.6 No No
8 empty 2.21 56.8 11 No No
9 empty 2.24 74.3 11.2 No No
10 empty 2.54 72.8 12.3 No No
5UU9_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.9 68.5 26.2 Yes No
2 empty 1.98 61.4 17.7 No No
3 bound 2.15 66.7 15.5 No No
4 empty 1.98 61.3 22.6 No No
5 empty 2.26 62.5 13.3 No No
6 empty 2.5 76.7 16.2 No No
7 empty 2.14 63.2 15.1 No No
8 bound 2.32 72.2 10.3 No No
9 bound 2.81 66.8 15.4 No No
10 bound 2.43 56.5 16.6 No No
3DO2_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 68.4 28.4 Yes No
2 empty 2.35 62 20.3 No No
3 empty 2.19 59.9 19.4 No No
4 empty 2.24 68.7 23.7 No No
5 empty 2 60.5 20.9 No No
6 empty 2.06 63.3 14.1 No No
7 empty 2.38 72.7 14.5 No No
8 empty 2.35 60.2 15.9 No No
9 empty 2.96 72.6 8.2 No No
10 empty 2.53 63.4 9.3 No No
5M69_E Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 66.1 33.5 Yes No
2 empty 2.35 71.4 23.6 No No
3 empty 2.23 60 23.5 No No
4 empty 2.12 66.3 20 No No
5 empty 2.38 63.2 17.2 No No
6 empty 1.91 60.7 22.5 No No
7 empty 2.37 70.8 10.5 No No
8 bound 2.32 58.9 12.3 No No
9 empty 2.52 75.8 8.9 No No
10 empty 2.54 67.5 8.8 No No
3T74_A Thermolysin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 70.2 29.7 Yes No
2 empty 2.2 60.3 17.9 No No
3 bound 2.15 68.5 16.3 No No
4 empty 2.38 62.1 17.3 No No
5 empty 1.95 60.9 24.3 No No
6 empty 2.29 72.4 15.7 No No
7 empty 2.28 66.4 12.2 No No
8 bound 2.32 58.9 11.9 No No
9 empty 2.44 66.9 12.9 No No
10 empty 2.25 72.2 11.7 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed98
Domains assessed as druggable using the strict criteria0
Domains assessed as druggable using the relaxed criteria92

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1FJ3_A (59850) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2Å Yes No
1FJO_A (59853) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2Å Yes No
1FJQ_A (59854) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1FJT_A (59857) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.15Å Yes No
1FJU_A (59858) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2Å Yes No
1FJV_A (59859) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2Å Yes No
1FJW_A (59860) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.87Å Yes No
1GXW_A (76379) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.18Å Yes No
1HYT_A (59005) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1KEI_A (77349) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
1KJO_A (77419) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
1KJP_A (77420) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
1KKK_A (77433) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
1KL6_A (77434) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.8Å Yes No
1KR6_A (77512) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.8Å Yes No
1KRO_A (77514) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
1KS7_A (77518) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1KTO_A (77542) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.9Å Yes No
1L3F_E (73537) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.3Å Yes No
1LNA_E (59006) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.9Å Yes No
1LNB_E (59007) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.8Å Yes No
1LNC_E (59008) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.8Å Yes No
1LND_E (59009) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1LNE_E (59010) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1LNF_E (59011) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å No No
1OS0_A (87371) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.1Å Yes No
1PE5_A (104123) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.65Å Yes No
1PE7_A (104124) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.82Å Yes No
1PE8_A (104125) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.8Å Yes No
1QF0_A (59029) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
1QF1_A (59030) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2Å Yes No
1QF2_A (59031) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.06Å Yes No
1THL_A (59044) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.58Å Yes No
1TLI_A (59045) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.05Å Yes No
1TLP_E (59046) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.3Å Yes No
1TLX_A (59047) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.1Å Yes No
1TMN_E (59048) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1TRL_A (4229527) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like (Homo Multimer) No No
1TRL_A (18263) Thermolysin C-terminal fragment of thermolysin, C-terminal fragment of thermolysin, C-terminal fragment of thermolysin No No
1TRL_B (18264) Thermolysin C-terminal fragment of thermolysin, C-terminal fragment of thermolysin, C-terminal fragment of thermolysin No No
1TRL_B (4229527) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like (Homo Multimer) No No
1Y3G_E (122594) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.1Å Yes No
1Z9G_E (124757) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
1ZDP_E (124945) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
2A7G_E (126337) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.85Å Yes No
2G4Z_A (134617) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.98Å Yes No
2TLI_A (59053) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.95Å Yes No
2TLX_A (59054) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.65Å Yes No
2TMN_E (59055) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
2WHZ_A (3240817) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.75Å Yes No
2WI0_A (3240818) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.95Å Yes No
3DNZ_A (4265537) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.18Å Yes No
3DO0_A (4055174) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.31Å No No
3DO1_A (4103084) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.31Å Yes No
3DO2_A (4144445) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.18Å Yes No
3EIM_A (3380648) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.88Å Yes No
3F28_A (3400060) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.68Å Yes No
3F2P_A (3400108) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.95Å Yes No
3FB0_A (3400600) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.59Å Yes No
3FBO_A (3400655) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.92Å Yes No
3FCQ_A (3400738) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.75Å Yes No
3FGD_A (3410001) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.33Å Yes No
3FLF_A (3410480) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.97Å Yes No
3FOR_A (3410711) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.93Å Yes No
3FV4_A (3420049) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.56Å Yes No
3FVP_A (3420075) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.41Å Yes No
3FWD_A (3420121) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.56Å Yes No
3FXP_A (3420205) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.05Å Yes No
3FXS_A (3420210) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.55Å Yes No
3LS7_A (3630113) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.98Å Yes No
3MS3_A (3630536) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.54Å Yes No
3MSA_A (4141045) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.66Å No No
3MSF_A (4267174) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.09Å Yes No
3MSN_A (4220867) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.97Å Yes No
3N21_A (4045238) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.87Å Yes No
3NN7_A (4212542) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.05Å Yes No
3P7P_E (3660509) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7Q_E (3660510) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7R_E (3660511) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7S_E (3660512) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7T_E (3660513) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7U_E (3660514) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7V_E (3660515) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3P7W_E (3660516) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
3SSB_A (3710473) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.8Å Yes No
3TLI_A (59062) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.95Å Yes No
3TMN_E (59063) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
4TLI_A (59064) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.95Å Yes No
4TLN_A (59065) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.3Å Yes No
4TMN_E (59066) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.7Å Yes No
5TLI_A (59067) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.1Å Yes No
5TLN_A (59068) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.3Å Yes No
5TMN_E (59069) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
6TLI_A (59070) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.1Å Yes No
6TMN_E (59071) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
7TLI_A (59072) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.95Å Yes No
7TLN_A (59073) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.3Å Yes No
8TLI_A (59074) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 2.2Å Yes No
8TLN_E (59075) Thermolysin Zincin-like, Metalloproteases ( zincins ) catalytic domain, Thermolysin-like 1.6Å Yes No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score