Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(P00761) - Overview - Molecular Target Synopsis

Protein


, Trypsin
Enzyme Classification 3.4.21.4
UniProt P00761

Also Known as TRYP_PIG


5XW1
CRYSTAL STRUCTURE OF PORCINE PANCREATIC TRYPSIN WITH TRIPEPTIDE INHIBITOR, PRN, AT PH10
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
231P00761-1

Sub-cellular localization


UniProt: is active in the following subcellular-locations: extracellular space, secreted.
GO terms: is active in the following subcellular-locations: extracellular space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
40 structures (58 chains) solved
10 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


has been screened with 114 compounds (121 bioactivities), 36 compounds have bioactivities that show binding affinity of <= 500nM (36 bioactivities). (see details)