Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

PRKAR1A (P00514) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) AKAP10 (O43572) BOVINE 3IM4_B 100 0 2.285Å - 2010-02-02
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - CATTLE 1NE4_A 100 0 2.4Å RP1 2004-01-13
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) Prkaca (P05132) BOVINE 4X6R_B 100 0 2.4Å - 2015-07-22
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) - CATTLE 2EZW_A 100 0 - 2006-02-14
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) DNAJB1 (P25685), PRKACA (P17612) BOVINE 6BYR_D 100 0 3.66Å - 2019-04-03
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE 3IIA_A 100 0 2.7Å - 2010-08-11
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6NO7_D 100 0 3.55Å - 2019-07-24
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) DNAJB1 (P25685), PRKACA (P17612) BOVINE 6BYR_B 100 0 3.66Å - 2019-04-03
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) AKAP10 (O43572) BOVINE 3IM4_A 100 0 2.285Å - 2010-02-02
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6BYS_F 100 0 4.75Å - 2019-04-03
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6NO7_B 100 0 3.55Å - 2019-07-24
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) C2orf88 (Q9BSF0) BOVINE 5HVZ_A 100 0 2Å - 2016-04-20
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 4MX3_B 100 0 3.88Å CMP 2014-01-15
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) Prkaca (P05132) BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 3PVB_B 100 0 3.3Å - 2011-02-02
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) C2orf88 (Q9BSF0) BOVINE 5HVZ_B 100 0 2Å - 2016-04-20
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - CATTLE 1NE6_A 100 0 2.3Å SP1 2004-01-13
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 4JV4_A 100 0 2.95Å 1OR 2013-09-18
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6BYS_H 100 0 4.75Å - 2019-04-03
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) Prkaca (P05132) BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 3FHI_B 100 0 2Å - 2009-04-14
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE 3PLQ_A 100 0 2.3Å RP2 2010-12-01
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - CATTLE 1RGS_A 100 0 2.8Å CMP 1996-12-07
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) - CATTLE 2EZW_B 100 0 - 2006-02-14
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6BYS_D 100 0 4.75Å - 2019-04-03
Regulatory subunit of type II PKA R-subunit (100%) (view alignment) PRKAR1A (P00514) - BOVINE 3IM3_A 100 0 2Å - 2010-02-02
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 4MX3_A 100 0 3.88Å CMP 2014-01-15
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) Prkaca (P05132) CATTLE 2QCS_B 100 0 2.2Å - 2007-11-06
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 3PNA_A 100 0 1.5Å CMP 2011-02-09
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - BOVINE,COW,DOMESTIC CATTLE,DOMESTIC COW 3PNA_B 100 0 1.5Å CMP 2011-02-09
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6NO7_H 100 0 3.55Å - 2019-07-24
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) Prkaca (P05132) BOVINE 5JR7_B 100 0 3.56Å - 2017-03-15
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - CATTLE 1RL3_A 100 0 2.7Å PCG 2004-07-06
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) - CATTLE 1RL3_B 100 0 2.7Å PCG 2004-07-06
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6BYS_B 100 0 4.75Å - 2019-04-03
Regulatory subunit of type II PKA R-subunit (100%), Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) PRKACA (P17612) BOVINE 6NO7_F 100 0 3.55Å - 2019-07-24
Cyclic nucleotide-binding domain (100%) (view alignment) PRKAR1A (P00514) Prkaca (P05132) BOVINE 5JR7_D 100 0 3.56Å - 2017-03-15