Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(P00323) - Overview - Molecular Target Synopsis

Protein


, Flavodoxin
UniProt P00323

Also Known as FLAV_DESVH

Low-potential electron donor to a number of redox enzymes.

5ZKP
CRYSTAL STRUCTURE OF THE HUMAN PLATELET-ACTIVATING FACTOR RECEPTOR IN COMPLEX WITH SR 27417
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
148P00323-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
35 structures (40 chains) solved
35 are solved in complex with at least one small molecule ligand
35 are solved with an approved drug

is solved in complex with the approved drug(s):

FMN/RIBOFLAVIN 5'-PHOSPHATE (1AKQ_A, 1AKR_A, 1AKT_A, 1AKU_A, 1AKV_A, 1AKW_A, 1AZL_A, 1C7E_A, 1C7E_B, 1C7F_A, 1C7F_B, 1F4P_A, 1FX1_A, 1I1O_A, 1J8Q_A, 1J9E_A, 1J9G_A, 1WSB_A, 1WSW_A, 1XT6_A, 1XYV_A, 1XYY_A, 2FX2_A, 3FX2_A, 4FX2_A, 5FX2_A, 5TGZ_A, 5V56_A, 5V56_B, 5V57_A, 5V57_B, 5XR8_A, 5XRA_A, 5YOB_A, 5YOC_A, 5YOE_A, 5YOG_A, 5ZKP_A),
CLR/CHOLESTEROL (5XR8_A, 5XRA_A),
RBF/RIBOFLAVIN (1BU5_A, 1BU5_B).

(see details)
Molecular Target 3D Synopsis