Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

LDOC1 (O95751) - Overview - Molecular Target Synopsis

Protein


LDOC1, Protein LDOC1
UniProt O95751

Also Known as LDOC1_HUMAN, LDOC1, BCUR1

May have an important role in the development and/or progression of some cancers. Interacts with NOD2.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
187ENSG00000182195ENST00000370526ENSP00000359557
146O95751-1

Sub-cellular localization


UniProt: LDOC1 is active in the following subcellular-locations: nucleus.
GO terms: LDOC1 is active in the following subcellular-locations: nucleolus, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project LDOC1 has gain in 0 cell-lines, loss in 30 cell-lines and no signal in 975 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: SNB_19, PC_3, CAKI_1

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 695T, G61, G124

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, A549, IMR-90

(see details)