HTR3B (O95264) - Overview - Molecular Target Synopsis
HTR3B, 5-hydroxytryptamine receptor 3B
Also Known as 5HT3B_HUMAN, HTR3B
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: HTR3B is active in the following subcellular-locations: cell membrane.
GO terms: HTR3B is active in the following subcellular-locations: cell surface, integral component of plasma membrane, neuron projection, plasma membrane, postsynaptic membrane, serotonin-activated cation-selective channel complex, synapse.