Molecular Target Synopsis
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TRPA1 (O75762) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 03/09/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 03/09/2019)


Chains assessed4
Chains with at least one site assessed as druggable using the strict criteria4
Chains with at least one site assessed as druggable using the relaxed criteria4


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
3J9P_D Transient receptor potential cation channel subfamily A member 1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.8 67.2 106.1 Yes Yes
2 empty 1.87 77 31.9 No No
3 empty 1.21 66.2 19.8 No No
4 empty 2.05 72.4 20.4 No No
5 empty 1.49 62 27.3 No No
6 empty 2.29 75 12.7 No No
7 empty 2.1 85.6 15.3 Yes No
8 empty 2.43 71.3 15.6 No No
9 empty 2.26 71.2 13.8 No No
10 empty 1.62 57.9 14.2 No No
3J9P_C Transient receptor potential cation channel subfamily A member 1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 67.6 107.4 Yes Yes
2 empty 1.87 77.6 32 No No
3 empty 1.21 65.4 25.6 No No
4 empty 2.23 73.3 20.5 No No
5 empty 1.49 60.3 24 No No
6 empty 2.28 74.2 13.3 No No
7 empty 2.12 85.1 19.6 Yes No
8 empty 2.42 70.6 13.8 No No
9 empty 2.26 70 14 No No
10 empty 1.61 58 14.6 No No
3J9P_A Transient receptor potential cation channel subfamily A member 1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 66.9 107.4 Yes Yes
2 empty 1.87 77.6 31.3 No No
3 empty 2.21 71.1 22.3 No No
4 empty 1.49 60.6 23 No No
5 empty 2.28 74.4 14.6 No No
6 empty 2.11 85 13.1 Yes No
7 empty 2.42 72.2 11.9 No No
8 empty 2.27 71.5 13.8 No No
9 empty 1.61 58.3 15 No No
10 empty 2.41 76.9 15.5 No No
3J9P_B Transient receptor potential cation channel subfamily A member 1 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 67.4 106.9 Yes Yes
2 empty 1.87 77.1 32.3 No No
3 empty 1.21 66.5 22.7 No No
4 empty 2.04 72.6 19 No No
5 empty 1.49 60.5 28.1 No No
6 empty 2.3 74.4 14.5 No No
7 empty 2.13 84.3 14 Yes No
8 empty 2.42 71.2 12.9 No No
9 empty 2.26 70.7 13.5 No No
10 empty 1.61 56.5 15.1 No No
Ligand-based Druggability Score: 0.95
Ligand-based Druggability Score Percentile: 90%
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score