Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MITF (O75030) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Helix-loop-helix DNA-binding domain (100%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 4ATK_A 97.46 3.0E-64 2.95Å - 2012-12-12
Helix-loop-helix DNA-binding domain (19%), Domain of unknown function (DUF3371) (6%) (view alignment) MITF (O75030) - HUMAN 4C7N_A 100 0 1.95Å - 2014-04-02
Helix-loop-helix DNA-binding domain (78%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - MOUSE 6FX5_A 93.75 1.0E-38 2.05Å - 2019-03-20
Helix-loop-helix DNA-binding domain (78%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 4ATH_A 97.5 6.0E-42 1.95Å - 2012-12-12
Helix-loop-helix DNA-binding domain (100%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 4ATI_A 97.46 3.0E-64 2.6Å - 2012-12-12
Helix-loop-helix DNA-binding domain (100%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 4ATK_B 97.46 3.0E-64 2.95Å - 2012-12-12
Helix-loop-helix DNA-binding domain (100%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 4ATI_B 97.46 3.0E-64 2.6Å - 2012-12-12
Helix-loop-helix DNA-binding domain (78%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - MOUSE 6FX5_B 93.75 1.0E-38 2.05Å - 2019-03-20
Helix-loop-helix DNA-binding domain (78%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 4ATH_B 97.5 6.0E-42 1.95Å - 2012-12-12
Helix-loop-helix DNA-binding domain (100%), Domain of unknown function (DUF3371) (6%) (view alignment) Mitf (Q08874) - HOUSE MOUSE 6G1L_A 96.64 1.0E-64 2.4Å - 2019-02-06