Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MAP3K13 (O43283) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
(view alignment) BRAF (P15056) - 5JSM_C 37.41 2.0E-40 6NB
(view alignment) BRAF (P15056) - 5CSW_B 37.04 1.0E-39 P06
(view alignment) BRAF (P15056) - 3TV6_A 36.69 7.0E-38 B0R
(view alignment) BRAF (P15056) - 4WO5_B 37.04 9.0E-40 324
(view alignment) BRAF (P15056) - 5HIE_C 37.73 8.0E-39 P06
(view alignment) BRAF (P15056) - 5ITA_A 37.04 2.0E-39 6DC
(view alignment) BRAF (P15056) - 4KSQ_A 36.69 1.0E-37 1SW
(view alignment) BRAF (P15056) - 3PPK_A 36.69 7.0E-38 FNI
(view alignment) CTR1 (Q05609) - 3PPZ_A 36.36 3.0E-42 STU
(view alignment) BRAF (P15056) - 4E4X_B 36.69 7.0E-38 T1Q
(view alignment) BRAF (P15056) - 6CAD_A 37.04 1.0E-39 EU4
(view alignment) BRAF (P15056) - 3Q4C_B 36.69 7.0E-38 -
(view alignment) BRAF (P15056) - 5JT2_C 37.41 2.0E-40 6NC
(view alignment) BRAF (P15056) - 3PRF_A 36.69 7.0E-38 FP3
(view alignment) BRAF (P15056) - 5JSM_D 37.41 2.0E-40 -
(view alignment) MAP3K20 (Q9NYL2) - 5X5O_A 38.41 4.0E-54 7Z0
(view alignment) MAP3K12 (Q12852) - 5VO2_A 86.94 0 9FV
(view alignment) MAP3K12 (Q12852) - 5CEN_A 86.94 0 -
(view alignment) BRAF (P15056) - 3C4C_A 37.04 1.0E-39 324
(view alignment) BRAF (P15056) - 4FC0_A 36.69 1.0E-37 0T2
(view alignment) BRAF (P15056) - 4JVG_D 37.04 1.0E-39 B96
(view alignment) CTR1 (Q05609) - 3P86_B 35.98 8.0E-42 -
(view alignment) BRAF (P15056) - 5CT7_B 36.69 1.0E-37 55J
(view alignment) BRAF (P15056) - 5HIE_A 37.73 8.0E-39 P06
(view alignment) BRAF (P15056) - 5C9C_B 37.05 1.0E-38 4Z5
(view alignment) - 4CSV_A 38.26 2.0E-45 STI
(view alignment) BRAF (P15056) - 3PPJ_B 36.69 7.0E-38 FOI
(view alignment) BRAF (P15056) - 4MNF_A 36.21 6.0E-39 29L
(view alignment) BRAF (P15056) - 3IDP_A 37.05 1.0E-38 L1E
(view alignment) BRAF (P15056) - 3TV6_B 36.69 7.0E-38 B0R
(view alignment) BRAF (P15056) - 4CQE_A 37.41 2.0E-40 CQE
(view alignment) BRAF (P15056) - 4G9C_B 36.69 7.0E-38 0WP
(view alignment) BRAF (P15056) - 4RZV_B 37.04 2.0E-39 032
(view alignment) BRAF (P15056) - 5C9C_A 37.05 1.0E-38 4Z5
(view alignment) BRAF (P15056) - 3PPJ_A 36.69 7.0E-38 FOI
(view alignment) BRAF (P15056) - 1UWJ_A 37.05 3.0E-38 BAX
(view alignment) BRAF (P15056) - 1UWH_B 37.05 8.0E-38 BAX
(view alignment) FES (P07332) - 3CD3_A 36.29 7.0E-36 STU
(view alignment) BRAF (P15056) - 4FK3_B 37.41 1.0E-40 -
(view alignment) BRAF (P15056) - 5HI2_A 38.11 1.0E-40 BAX
(view alignment) BRAF (P15056) - 5VAL_B 36.69 1.0E-37 92D
(view alignment) BRAF (P15056) - 4XV1_B 37.41 1.0E-40 -
(view alignment) BRAF (P15056) - 5HID_B 38.11 1.0E-40 B1E
(view alignment) MAP3K20 (Q9NYL2) - 5HES_B 38.41 4.0E-54 032
(view alignment) BRAF (P15056) - 3PRI_A 36.69 7.0E-38 FP4
(view alignment) BRAF (P15056) - 4EHE_A 36.69 7.0E-38 RI8
(view alignment) BMX (P51813) - 3SXR_B 35.55 4.0E-36 1N1
(view alignment) BRAF (P15056) - 3OG7_A 37.78 6.0E-41 032
(view alignment) BRAF (P15056) - 3PSD_B 36.69 7.0E-38 SM7
(view alignment) BRAF (P15056) - 5JT2_A 37.41 2.0E-40 BEN 6NC
(view alignment) BRAF (P15056) - 3PSB_A 36.69 7.0E-38 SM6
(view alignment) BRAF (P15056) - 4MBJ_A 36.69 8.0E-38 DFS
(view alignment) MAP3K12 (Q12852) - 5CEQ_A 86.94 0 50F
(view alignment) BRAF (P15056) - 4EHG_A 37.05 1.0E-38 RI9
(view alignment) BRAF (P15056) - 3OG7_B 37.78 6.0E-41 -
(view alignment) BRAF (P15056) - 4PP7_B 36.69 7.0E-38 2VX
(view alignment) BRAF (P15056) - 3SKC_A 36.69 7.0E-38 BR2
(view alignment) BRAF (P15056) - 4G9R_A 37.05 1.0E-38 B1E
(view alignment) BRAF (P15056) - 4XV3_B 37.41 1.0E-40 -
(view alignment) BRAF (P15056) - 5JSM_A 37.41 2.0E-40 BEN
(view alignment) BRAF (P15056) - 3D4Q_A 36.69 7.0E-38 SM5
(view alignment) BRAF (P15056) - 3II5_A 36.69 7.0E-38 831
(view alignment) BRAF (P15056) - 6B8U_A 36.69 1.0E-37 8EN
(view alignment) BRAF (P15056) MAP2K1 (Q02750) 4MNE_C 36.69 8.0E-38 -
(view alignment) BRAF (P15056) - 4JVG_A 37.04 1.0E-39 B96
(view alignment) BRAF (P15056) - 6CAD_B 37.04 1.0E-39 EU4
(view alignment) BRAF (P15056) - 4DBN_A 36.69 1.0E-37 0JA
(view alignment) BRAF (P15056) - 4JVG_C 37.04 1.0E-39 B96
(view alignment) BRAF (P15056) - 3TV4_B 36.69 7.0E-38 TV4
(view alignment) BRAF (P15056) - 4E26_B 36.69 7.0E-38 734
(view alignment) BRAF (P15056) - 3PRF_B 36.69 7.0E-38 FP3
(view alignment) MAP3K12 (Q12852) - 5CEO_A 86.94 0 50D
(view alignment) BRAF (P15056) - 3Q4C_A 36.69 7.0E-38 RSW
(view alignment) BRAF (P15056) - 4R5Y_A 37.41 1.0E-40 3K3
(view alignment) BRAF (P15056) - 5ITA_B 37.04 2.0E-39 6DC
(view alignment) BRAF (P15056) - 4JVG_B 37.04 1.0E-39 B96
(view alignment) BRAF (P15056) - 4MBJ_B 36.69 8.0E-38 DFS
(view alignment) CTR1 (Q05609) - 3P86_A 35.98 8.0E-42 STU
(view alignment) BRAF (P15056) - 4G9C_A 36.69 7.0E-38 0WP
(view alignment) BRAF (P15056) MAP2K1 (Q02750) 4MNE_F 36.69 8.0E-38 -
(view alignment) BRAF (P15056) - 4YHT_B 36.59 6.0E-38 4EF
(view alignment) BRAF (P15056) - 4KSP_B 36.69 1.0E-37 1SU
(view alignment) BMX (P51813) - 3SXS_A 35.55 4.0E-36 PP2
(view alignment) BRAF (P15056) - 5HIE_B 37.73 8.0E-39 P06
(view alignment) BRAF (P15056) - 4FC0_B 36.69 1.0E-37 0T2
(view alignment) BRAF (P15056) - 5JRQ_B 37.41 2.0E-40 6N9
(view alignment) BRAF (P15056) - 3PPK_B 36.69 7.0E-38 FNI
(view alignment) BRAF (P15056) - 4XV2_B 37.41 1.0E-40 P06
(view alignment) BRAF (P15056) - 4WO5_A 37.04 9.0E-40 324
(view alignment) MAP3K9 (P80192) - 3DTC_A 44.03 9.0E-60 VIN
(view alignment) MAP3K21 (Q5TCX8) - 4UYA_A 41.78 2.0E-65 AGS
(view alignment) BRAF (P15056) - 3C4C_B 37.04 1.0E-39 324
(view alignment) BRAF (P15056) - 1UWJ_B 37.05 3.0E-38 BAX
(view alignment) BRAF (P15056) - 4XV1_A 37.41 1.0E-40 904
(view alignment) FES (P07332) - 3BKB_A 36.29 7.0E-36 STU
(view alignment) BRAF (P15056) - 5FD2_B 36.69 9.0E-38 5XJ
(view alignment) BRAF (P15056) - 4XV3_A 37.41 1.0E-40 P02
(view alignment) BRAF (P15056) - 3PSB_B 36.69 7.0E-38 SM6
(view alignment) MAP3K20 (Q9NYL2) - 5HES_A 38.41 4.0E-54 032
(view alignment) BRAF (P15056) - 4H58_C 36.69 2.0E-37 -
(view alignment) BRAF (P15056) - 3SKC_B 36.69 7.0E-38 BR2
(view alignment) BRAF (P15056) - 3TV4_A 36.69 7.0E-38 TV4
(view alignment) BRAF (P15056) - 4E4X_A 36.69 7.0E-38 T1Q
(view alignment) BRAF (P15056) - 4RZW_A 37.04 2.0E-39 B1E
(view alignment) BRAF (P15056) - 4XV9_A 37.04 9.0E-40 1OO
(view alignment) BRAF (P15056) - 5HID_A 38.11 1.0E-40 B1E
(view alignment) FES (P07332) - 4E93_A 36.29 7.0E-36 GUI
(view alignment) BRAF (P15056) - 4KSQ_B 36.69 1.0E-37 1SW
(view alignment) MAP3K9 (P80192) - 4UY9_B 40.98 2.0E-64 -
(view alignment) BRAF (P15056) - 4DBN_B 36.69 1.0E-37 0JA
(view alignment) BRAF (P15056) - 4FK3_A 37.41 1.0E-40 325
(view alignment) BRAF (P15056) - 5CSW_A 37.04 1.0E-39 P06
(view alignment) BRAF (P15056) - 5JT2_D 37.41 2.0E-40 -
(view alignment) BRAF (P15056) - 4MNF_B 36.21 6.0E-39 29L
(view alignment) BRAF (P15056) - 1UWH_A 37.05 8.0E-38 BAX
(view alignment) MAP3K12 (Q12852) - 5CEP_A 86.94 0 50E
(view alignment) BRAF (P15056) - 5CSX_A 37.04 1.0E-39 54J GLC
(view alignment) BRAF (P15056) - 5CT7_A 36.69 1.0E-37 55J
(view alignment) BRAF (P15056) - 5VAL_A 36.69 1.0E-37 92D
(view alignment) FES (P07332) - 3CBL_A 36.29 7.0E-36 STU
(view alignment) CTR1 (Q05609) - 3PPZ_B 36.36 3.0E-42 -
(view alignment) BRAF (P15056) - 4H58_A 36.69 2.0E-37 10Z
(view alignment) BRAF (P15056) - 4E26_A 36.69 7.0E-38 734
(view alignment) MAP3K9 (P80192) - 4UY9_A 40.98 2.0E-64 -
(view alignment) BRAF (P15056) - 6B8U_B 36.69 1.0E-37 8EN
(view alignment) BRAF (P15056) - 4PP7_A 36.69 7.0E-38 2VX
(view alignment) BRAF (P15056) - 4R5Y_B 37.41 1.0E-40 3K3
(view alignment) BRAF (P15056) - 3Q96_B 36.69 1.0E-37 0NF
(view alignment) BRAF (P15056) - 5FD2_A 36.69 9.0E-38 5XJ
(view alignment) BRAF (P15056) - 4YHT_A 36.59 6.0E-38 4EF
(view alignment) BRAF (P15056) - 5VAM_B 36.69 1.0E-37 92J
(view alignment) BRAF (P15056) - 5JT2_B 37.41 2.0E-40 BEN
(view alignment) BRAF (P15056) - 3Q96_A 36.69 1.0E-37 0NF
(view alignment) BRAF (P15056) - 4H58_B 36.69 2.0E-37 -
(view alignment) BRAF (P15056) - 3D4Q_B 36.69 7.0E-38 SM5
(view alignment) BRAF (P15056) - 5JRQ_A 37.41 2.0E-40 6N9
(view alignment) MAP3K12 (Q12852) - 5VO1_A 86.94 0 9FS
(view alignment) BRAF (P15056) - 2FB8_B 36.69 1.0E-37 215
(view alignment) BRAF (P15056) - 5VAM_A 36.69 1.0E-37 92J
(view alignment) BRAF (P15056) - 4CQE_B 37.41 2.0E-40 CQE
(view alignment) BRAF (P15056) - 3II5_B 36.69 7.0E-38 831
(view alignment) BRAF (P15056) MAP2K1 (Q02750) 4MNE_G 36.69 8.0E-38 -
(view alignment) BRAF (P15056) - 3PRI_B 36.69 7.0E-38 FP4
(view alignment) BRAF (P15056) - 4RZW_B 37.04 2.0E-39 B1E
(view alignment) BRAF (P15056) - 2FB8_A 36.69 1.0E-37 215
(view alignment) BRAF (P15056) - 4RZV_A 37.04 2.0E-39 032
(view alignment) BRAF (P15056) - 4KSP_A 36.69 1.0E-37 1SU
(view alignment) BRAF (P15056) - 4EHG_B 37.05 1.0E-38 RI9
(view alignment) BRAF (P15056) - 4XV2_A 37.41 1.0E-40 P06
(view alignment) BRAF (P15056) - 3IDP_B 37.05 1.0E-38 L1E
(view alignment) BRAF (P15056) - 3PSD_A 36.69 7.0E-38 SM7
(view alignment) BRAF (P15056) - 4G9R_B 37.05 1.0E-38 B1E
(view alignment) BRAF (P15056) MAP2K1 (Q02750) 4MNE_B 36.69 8.0E-38 -
(view alignment) BMX (P51813) - 3SXR_A 35.55 4.0E-36 1N1
(view alignment) BRAF (P15056) - 5JSM_B 37.41 2.0E-40 6NB BEN
(view alignment) BRAF (P15056) - 5HIE_D 37.73 8.0E-39 P06
(view alignment) - 4UEU_A 38.26 2.0E-45 ACP
(view alignment) BRAF (P15056) - 4EHE_B 36.69 7.0E-38 RI8