Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

glpK (O34153) - Overview - Molecular Target Synopsis

Protein


glpK, Glycerol kinase
Enzyme Classification 2.7.1.30
UniProt O34153

Also Known as GLPK_ENTCA, glpK

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. Homotetramer and homodimer (in equilibrium).

3H3N
GLYCEROL KINASE H232R WITH GLYCEROL
RCSB/PDB
Inspect Structure
See all 3D Structures for glpK

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
506O34153-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project glpK has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For glpK there are:
8 structures (20 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


glpK has been screened with compounds ( bioactivities). (see details)