Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

kinD (O31671) - Overview - Molecular Target Synopsis

Protein


kinD, Sporulation kinase D
Enzyme Classification 2.7.13.3
UniProt O31671

Also Known as KIND_BACSU, kinD, ykvD

Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions.

4JGO
THE CRYSTAL STRUCTURE OF SPORULATION KINASE D SENSOR DOMAIN FROM BACILLUS SUBTILIS SUBSP.
RCSB/PDB
Inspect Structure
See all 3D Structures for kinD

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
506O31671-1

Sub-cellular localization


UniProt: kinD is active in the following subcellular-locations: cell membrane.
GO terms: kinD is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project kinD has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For kinD there are:
4 structures (8 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


kinD has been screened with compounds ( bioactivities). (see details)