Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ttrD (O30077) - Overview - Molecular Target Synopsis

Protein


ttrD, Tat proofreading chaperone TtrD
UniProt O30077

Also Known as TTRD_ARCFU, ttrD

Binds specifically to the Tat signal peptide of the TtrA subunit of the tetrathionate reductase. Monomer.

2Y6Y
CRYSTAL STRUCTURE OF TTRD FROM ARCHAEOGLOBUS FULGIDUS
RCSB/PDB
Inspect Structure
See all 3D Structures for ttrD

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
174O30077-1

Sub-cellular localization


UniProt: ttrD is active in the following subcellular-locations: cytoplasm.
GO terms: ttrD is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ttrD has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For ttrD there are:
4 structures (7 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis